Clinical Oncology Week articles from July 2003

Clinical Oncology Week archives from July 2003

Diet high in nutrients such as antioxidant vitamins or calcium may be protective.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Diet high in nutrients such as antioxidant vitamins or calcium may be protective. According to a study from the United States, "Primary prevention of colonic adenomas and cancer through dietary...

Clinical signs, symptoms indicate disease severity.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- If a patient has the skin cancer melanoma, clinical signs and symptoms can be used by the physician to better assess the extent of disease, prognosis, and appropriate therapy, according to a study...

Quality of evidence supporting myeloma treatment recommendations is modest.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- The quality of evidence supporting treatment recommendations for multiple myeloma is modest, at best. "We have done a systematic review of all randomized studies in myeloma, identified through a...

Interactive multiplanar review may improve detection of peritoneal metastases.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Interactive multiplanar review may improve detection of peritoneal metastases in ovarian cancer. "Ovarian cancer is usually in an advanced stage at diagnosis due to the presence of peritoneal...

All forms of pancreatitis increase the risk of pancreatic cancer.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- All forms of pancreatitis increase the risk of pancreatic cancer. "Pancreatic cancer remains one of the most recalcitrant of all cancers," scientists writing in the journal Hematology-Oncology...

Future therapies based on AKT inhibition may help control invasion, metastasis.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Future therapies based on AKT inhibition may help control invasion and metastasis. According to recent research published in the journal Cancer Research, "Epithelial-mesenchymal transition (EMT) is...

Adrenal carcinoma can cause secondary amyloidosis.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Adrenal carcinoma can cause secondary amyloidosis. According to a study from Turkey, "In a 53-year-old male patient with metastatic adrenal carcinoma, treatment with mitotane was instituted but he...

Cytotoxic T-cell lymphoma development may result in internal bleeding.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Cytotoxic T-cell lymphoma and other cancers can occur in Behcet disease patients; may not have a good prognosis. According to recent research published in the International Journal of Hematology,...

Clear cell myomelanocytic tumor is histologically distinctive.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Clear cell myelomelanocytic tumors may be ubiquitous and will be easy to characterize histologically. "Clear cell myomelanocytic tumors are a recently described neoplastic growth considered to be a...

Arsenic trioxide may be an effective chemotherapeutic agent for malignant glioma.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Arsenic trioxide may be an effective chemotherapeutic agent for malignant glioma. According to published research from the United States, "Recent clinical data show that arsenic trioxide...

4-CE and quinone conjugates were highly significant predictors of breast cancer.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- 4-CE and quinone conjugates were highly significant predictors of breast cancer. According to recent research from the United States, "Exposure to estrogens has been associated with an increased...

Isoflavones may not exert an estrogenic effect on mammographic density.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Isoflavones may not exert an estrogenic effect on mammographic density. "The estrogenic and antiestrogenic effects of isoflavones, phytoestrogens contained in soy foods, have been proposed as...

Psychosocial interventions should be integrated into disease management programs.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Psychosocial interventions should be integrated into disease management programs for breast cancer. According to published research from Germany, "Breast cancer patients are subject not only to...

Upper lobe pulmonary fibrosis can be associated with high-dose chemotherapy.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Upper lobe pulmonary fibrosis can be associated with high-dose chemotherapy. According to recent research published in the journal Mayo Clinic Proceedings, "Upper lobe fibrotic lung disease is most...

Pain management poorer in advanced cancer than terminal cancer patients.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Pain was managed more poorly in advanced cancer than terminal cancer patients. "The aim of this study was to evaluate the prevalence, severity, and management of pain in Korean patients with...

Frequent raw/cooked fish intake may decrease the risk of colorectal cancer.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Frequent raw/cooked fish intake may decrease the risk of colorectal cancer. "Several clinical studies have suggested that supplementation with fish oils can suppress the proliferation of colorectal...

Olanzapine was well tolerated and may reduce the incidence of delayed emesis.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Olanzapine was well tolerated and may reduce the incidence of delayed emesis. According to recent research from the United States, "Chemotherapy-induced delayed emesis (DE) affects approximately...

Increase in serum CA125 is a possible marker for epithelioid sarcoma.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Increasing serum CA125 measurements appear to be a marker for epithelioid sarcoma. According to a study from Japan, "Epithelioid sarcoma (ES) is a musculoskeletal malignant tumor with epithelioid...

Study links common indicator of early puberty to obesity and breast cancer.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- A new Cincinnati Children's Hospital Medical Center study underscores the link between early onset of puberty and obesity, and it provides the first suggestion of an increased risk of breast cancer for...

Current screening programs have significant uncertainties.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Current screening programs have significant uncertainties. "Our goal is to eliminate gastrointestinal cancer," researchers in the United States report. "This may be achieved by the prevention...

H pylori infection should be eradicated early in high-risk groups.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- H pylori infection should be eradicated early in high-risk groups. "Gastric carcinoma is a worldwide disease with widely variable incidence in different geographic areas. In contrast to an overall...

Barrett metaplasia is the no. 1 risk factor for esophageal adenocarcinoma.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Barrett metaplasia is the No. 1 risk factor for esophageal adenocarcinoma. According to a study from the United States, "Barrett's metaplasia is found in approximately 12% to 18% of patients...

Dedicated multidetector CT is valuable in evaluating gastric wall disease.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Dedicated multidetector CT is valuable in evaluating gastric wall disease. According to a study from Austria, "Multidetector computed tomography (CT) offers new opportunities in imaging of the...

A new grading system should help reduce severe therapy-related side effects.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- A new grading system should help reduce severe therapy-related side effects. "The prognostic value of histologic classification and single histomorphologic parameters in Hodgkin disease has been...

Cell cycle proteins are altered, cyclin 1 is of prognostic value.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- The cell cycle protein cyclin D1 appears to be prognostic for survival in laryngeal squamous cell carcinoma. "Alterations of cell cycle proteins contribute to the development and biological...

Acute renal failure can develop secondary to imatinib mesylate treatment.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Acute renal failure can develop secondary to imatinib mesylate treatment. According to recent research published in the journal Leukemia & Lymphoma, "A 58-year-old woman with chronic myeloid...

Atypical hemophagocytic lymphohistiocytosis may occur in leukemia patients.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Atypical hemophagocytic lymphohistiocytosis may occur in leukemia patients. According to recent research published in the journal Leukemia & Lymphoma, "We report a rare case of acute lymphoblastic...

Patients receiving i.v. 6-mercaptopurine had decreased survival after ALL relapse.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Patients assigned to i.v. 6-mercaptopurine had decreased survival after ALL relapse. "Conventional therapy for childhood acute lymphoblastic leukemia (ALL) includes prednisone and oral...

Pediatric ALL patients regain most lymphocyte populations, have abnormal NK, TS.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Following chemotherapy, children who had acute lymphoblastic leukemia regain a balance of most lymphocyte populations, with the exception of NK and TS cells. "The immunosuppressive effect of...

p57KIP2 is frequently methylated in adult patients with ALL.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- p57KIP2 is frequently methylated in adult patients with ALL. "P57KIP2 is a cyclin-dependent kinase inhibitor silenced in a variety of human malignancies. DNA methylation of a region surrounding the...

Ceramide accumulation precedes caspase-3 activation during apoptosis.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Ceramide accumulation precedes caspase-3 activation during apoptosis. "Ceramide, the basic structural unit of sphingolipids, controls the balance between cell growth and death by inducing...

Dietary fruit, vegetables protect against somatic lung cancer mutation in vivo.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Dietary fruit and vegetables protect against somatic lung cancer mutation in vivo. According to recent research published in the journal Carcinogenesis, "Epidemiological studies have demonstrated...

PET scan, endoscopic ultrasound show promise in staging for lung cancer surgery.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- PET scanning and endoscopic ultrasound show promise in staging for lung cancer surgery. According to published research from the United States, "Non-small cell lung cancer (NSCLC) in the United...

A specific degree of neural differentiation isn't present in medulloblastoma.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Medulloblastoma can have all degrees of neural differentiation, but all stain for neuron specific enolase and also glial fibrillary acidic protein in reactive astrocytes. "Electron microscopy was...

Pap smear often finds many high-grade epithelial malignant cells.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Pap smear often finds many high-grade epithelial malignant cells. According to a study from the United States, "Malignant mixed Mullerian tumor is a rare neoplasm that occurs most frequently in...

Bisphosphonates are treatment of choice for patients with MM, bone complications.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Bisphosphonates are the treatment of choice for patients with bone complications in multiple myeloma. "Osteolytic bone disease is a major cause of morbidity in patients with multiple myeloma. Our...

Tc-99m MIBI SPECT effective in detecting recurrent nasopharyngeal carcinoma.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Tc-99m MIBI SPECT may be effective in detecting recurrent nasopharyngeal carcinoma. "The aim of this study was to evaluate the effectiveness of technetium-99m methoxyisobutylisonitrile (Tc-99m MIBI)...

Hypercalcemia can result from calcium, vitamin D, and shark cartilage.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Hypercalcemia can result from calcium, vitamin D, and shark cartilage. "The use of nutritional supplements in the general population and in cancer patients has become very popular," scientists in...

Risk of oral cancer was increased among subjects consuming meat.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Risk of oral cancer was increased among subjects consuming meat. According to recent research published in the European Journal of Cancer Prevention, "Between 1996 and 1999, we carried out a study...

Chronic pancreatitis may be linked to pancreatic cancer.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Chronic pancreatitis may be linked to pancreatic cancer. "Pancreatic adenocarcinoma is a disease with high mortality for which chronic pancreatitis confers a markedly increased risk," scientists...

Chemotherapy should include CNS prophylaxis in localized primary breast lymphoma.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Chemotherapy should include CNS prophylaxis in localized primary breast lymphoma. "Primary breast lymphoma (PBL) is a rare form of localized extranodal lymphoma. Few reports are available in the...

C-11-acetate/F-18-FDG PET may be valuable in prostate cancer patient follow-up.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- C-11-acetate/F-18-FDG PET may be valuable in prostate cancer patient follow-up. According to a study from Germany, "Visualization of primary prostate cancer, its relapse and its metastases is a...

Genetic test shows promise for early prostate cancer detection.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Results of a study in the July 2003 issue of European Urology suggest that a non-invasive genetic test could soon aid the diagnosis of prostate cancer. Early detection of prostate cancer, the second...

Study supports lengthening screening interval.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- A new study estimates that one half of the cancers detected by an annual screening program for prostate cancer among men between the ages of 55 and 67 would not have been diagnosed in the absence of...

Intraoral sebaceous carcinoma can be treated with a wide surgical excision.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Intraoral sebaceous carcinoma can be treated with a wide surgical excision. According to recent research from Germany, "Sebaceous carcinoma in the oral cavity is extremely rare, and we have found...

In U.S.A., nosocomial infections of cancer patients are mostly staphylococcal.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- In the United States, nosocomial infections of cancer patients are mostly due to Staphylococci. According to published research from Germany, "A total of 2340 patients with underlying malignancy...

Celiac disease and other GI diseases are risk factors for small-bowel malignancy.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Celiac disease and other GI diseases are risk factors for small-bowel malignancy. According to recent research published in the journal Hematology-Oncology Clinics of North America, "Malignancies of...

Stent deployment is successful for peripheral stenosis after radiation therapy.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Stent deployment is successful for peripheral stenosis after radiation therapy. "Arterial occlusive disease is a well-known complication of radiation therapy, but venous thrombosis and occlusion...

Xerostomia and hypofunction of the salivary glands may occur in cancer therapy.
July 7, 2003... 2003 JUL 7 - (NewsRx.com & NewsRx.net) -- Xerostomia and hypofunction of the salivary glands may occur in cancer therapy. According to recent research from Denmark, "This review presents data from the literature on oral adverse reactions...

Imaging glioblastoma multiforme is improved by recent advances.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Imaging glioblastoma multiforme is improved by recent advances. "Glioblastoma multiforme are infiltrative lesions that have a high degree of heterogeneity, both within and between different...

MR-compatible probe allows ablation of liver tumors under MR guidance.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- MR-compatible probe allows ablation of liver tumors under MR guidance. According to published research from Switzerland, "Percutaneous radio-frequency (RF) ablation of liver tumors is usually...

A questionnaire may triage breast cancer risk based on family history.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- A questionnaire may triage breast cancer risk based on family history. "Family history of breast cancer is a more important aspect of clinical management following the discovery of the genes BRCA1...

Beta Pix-alpha, protein involved in cell motility, overexpressed in breast cancer.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Beta Pix-alpha, a protein involved in cell motility, is expressed much more in most breast cancer tissues. According to published research from South Korea, "Interacting exchange factor (betaPix)...

Precancers now categorized and in a comprehensive list.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- The first comprehensive listing and classification of precancers, drawn from the medical literature, has been created. Using this classification, the precancers have been organized into groups...

Irradiation of the spleen can be used to treat splenomegaly.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Splenic irradiation can be used to treat splenomegaly in cancer, polycythemia, and myelofibrosis patients. According to published research from the United States, "We analyzed the efficacy of...

PET and SPECT imaging of gliomas can evaluate treatment response.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- PET and SPECT imaging of gliomas can evaluate treatment response. According to a study from Belgium, "Over the last two decades the large volume of research involving various brain tracers has shed...

Bilateral breast cancer patients have a higher rate of distant metastases.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Bilateral breast cancer patients have a higher rate of distant metastases. "The purpose of this study was to address the question whether patients with bilateral breast cancer (BBC) have a worse...

Combined tamoxifen and 2-methoxyestradiol showed an additive inhibitory effect.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Combined tamoxifen and 2-methoxyestradiol showed an additive inhibitory effect in breast cancer. According to a study from Germany, "Endocrine therapy is widely accepted for the treatment of...

Docetaxel-ifosfamide combination is encouraging after phase II trial.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Docetaxel-ifosfamide combination is encouraging after phase II trial. According to published research from Greece, "Given the established individual activity of docetaxel and ifosfamide in...

Prognostic indices in breast cancer are related to race.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Prognostic indices in breast cancer are related to race. "African-American (AA) women have a higher mortality from breast cancer than Caucasians (C). This may be attributed to stage of disease at...

Quality of life seems to be better after conservative treatment of breast cancer.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Quality of life seems to be better after conservative treatment of breast cancer. According to recent research from the Netherlands, "Mastectomy and breast-conserving treatment have proven equally...

Research suggests the importance of spiritual belief systems for health.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Research suggests the importance of spiritual belief systems for health. According to recent research from the United States, "Spirituality has been shown to be associated with health, and is an...

Vitamin D-3 analogs represent a novel treatment approach for human cancer.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Vitamin D-3 analogs represent a novel treatment approach for human cancer. According to a study from the United States, "1,25-dihydroxyvitamin D-3 (1,25(OH)[subscript]2D-3), a steroid hormone...

Papillary endothelial hyperplasia is often diagnosed as angiosarcoma.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Papillary endothelial hyperplasia is often diagnosed as angiosarcoma. According to published research from the United States, "Seventeen cases of papillary endothelial hyperplasia (PEH, Masson's...

Intraoperative frozen sections in neurosurgery are diagnostically reliable.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Intraoperative frozen sections in neurosurgery are diagnostically reliable. "Clinicians order neurosurgery frozen sections in order to answer three questions: is the specimen tumor tissue? Is it...

HRT increases risk of gallbladder, breast, endometrial, and bladder cancer.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- HRT increases risk of gallbladder, breast, endometrial, and bladder cancer. "To provide comprehensive and quantitative information on the benefits and risks of hormone replacement therapy (HRT) on...

Researchers develop age-conditional probabilities of developing cancer.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Researchers develop age-conditional probabilities of developing cancer. "We propose an estimator of the probability of developing a disease in a given age range, conditional on never having...

FGF-2 acts to inhibit versus potentiate chemotherapeutic drug action.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- FGF-2 acts to inhibit versus potentiate chemotherapeutic drug action. "The development of resistance to chemotherapy by tumor cells remains a constant limitation to the treatment of cancer."...

Short-term carcinogen exposures in early life may yield a greater tumor response.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Short-term carcinogen exposures in early life may yield a greater tumor response. According to a study from the United States, "For the vast majority of chemicals that have cancer potency estimates...

Solid variants of extraskeletal myxoid chondrosarcoma may exist.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Solid variants of extraskeletal myxoid chondrosarcoma may exist. According to a study from Scotland, "Extraskeletal myxoid chondrosarcoma (EMC) is a rare soft tissue tumor associated with the...

Fecal tagging in MR colonography obviates the need for bowel cleansing.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Fecal tagging in MR colonography obviates the need for bowel cleansing. According to a study from Germany, "Colorectal cancer screening has vast potential. Beyond considerations for cost and...

Granulomatous eccrinotropic lymphomatoid papulosis can be misdiagnosed.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Granulomatous eccrinotropic lymphomatoid papulosis is a disease that can be confused with other dermatological, cancerous, and immunological conditions, but does not lead to development of lymphoma....

Chromoscopy with advanced endoscopic technology have great diagnostic potential.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Chromoscopy with advanced endoscopic technology have great diagnostic potential. "In the past few years, optical magnification endoscopy and chromoscopy have gained renewed interest in the West as...

Extrapelvic, extraperitoneal spread of recurrent stomach cancer is rare.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Extrapelvic and extraperitoneal spread of recurrent stomach cancer is rare. According to a study from South Korea, "We report two cases of unusual combined extrapelvic and extraperitoneal extension...

PET scan reliably rules out the presence of disease in staging and restaging.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- PET scan reliably rules out the presence of disease in staging and restaging. According to published research from Switzerland, "The purpose of this study was to calculate disease probabilities...

Researchers suggest that raising coverage rates will improve cancer treatment.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Researchers suggest that raising coverage rates will improve cancer treatment. According to recent research from the United States, "Over 1.3 million new cancer cases are diagnosed each year. ...

Lymphoma associated disease of B or T origin have different cytokine profiles.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Serum cytokine profiles differ between B and T cell lymphomas in hemophagocytic syndrome patients. "To elucidate the differences in pathogenesis between lymphoma-associated hemophagocytic...

Methotrexate conjugated to human serum albumin exhibits antitumor activity.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Methotrexate conjugated to human serum albumin exhibits antitumor activity. "To avoid systemic toxicity of the cytotoxic drug methotrexate (MTX) and to improve tumor selectivity, MTX was bound to...

Inflammatory myofibroblastic tumors, once removed, do not appear to recur.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Inflammatory myofibroblastic tumors of the kidney, once removed, do not appear to recur or metastasize. "Inflammatory myofibroblastic tumor is a rare entity composed of spindle cells admixed with...

Cholesterol-modulating agents kill acute myeloid leukemia cells.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Cholesterol-modulating agents kill acute myeloid leukemia cells. "The mevalonate pathway produces many critical substances in cells, including sterols essential for membrane structure and...

Infections complicate cases of acute promyelocytic leukemia treated with AIDA regimen.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Infections complicate cases of acute promyelocytic leukemia with AIDA regimen. According to recent research from Italy, "Infections represent a frequent complication of chemotherapy used for acute...

PML/RARa expression is not a determinant of arsenic sensitivity in leukemia.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- PML/RARa expression is not a determinant of arsenic sensitivity in leukemia. "Arsenic trioxide (AS[subscript]2O[subscript]3) is an effective treatment for acute promyelocytic leukemia (APL), but is...

Linear spiradenoma can undergo rapid, focal malignant transformation.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Linear spiradenoma can undergo rapid, focal malignant transformation. According to recent research from Germany, "Malignant spiradenoma is an exceedingly rare adnexal tumor clinically...

Study does not support using intra-arterial administration of I-131-Lipiodol.
July 14, 2003... 2003 JUL 14 - (NewsRx.com & NewsRx.net) -- Study does not support using intra-arterial administration of I-131-Lipiodol. According to recent research from the Netherlands, "Several authors have demonstrated the good tolerance of hepatic...