Clinical Oncology Week articles from January 2009

Clinical Oncology Week archives from January 2009

Research from University of Sydney, Department of Surgery in the area of cancer gene therapy published.
January 5, 2009... Fresh data on cancer gene therapy are presented in the report 'Cytosolic phospholipase A2-alpha: a potential therapeutic target for prostate cancer.' "Cytosolic phospholipase A2-alpha (cPLA2-alpha) provides intracellular arachidonic acid to...

Researchers at West Virginia University, Mary Babb Randolph Cancer Center have published new data on cancer gene therapy.(Report)
January 5, 2009... New research, 'Confirmation of gene expression-based prediction of survival in non-small cell lung cancer,' is the subject of a report. "It is a critical challenge to determine the risk of recurrence in early stage non-small cell lung cancer...

Researchers from Kyoto University discuss findings in cancer gene therapy.
January 5, 2009... New investigation results, 'Adenovirus vectors with chimeric type 5 and 35 fiber proteins exhibit enhanced transfection of human pancreatic cancer cells,' are detailed in a study published in International Journal of Oncology. "Adenovirus (Ad)...

Scientists at University of Texas, M. D. Anderson Cancer Center publish research in cancer gene therapy.
January 5, 2009... Scientists discuss in '1,1-Bis(3'-indolyl)-1-(p-chlorophenyl)methane activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth' new findings in cancer gene therapy. "Nurr1 is an orphan nuclear receptor and a member of the...

Researchers from Medical University of Vienna report on findings in cancer therapy vaccines.
January 5, 2009... Researchers detail in 'Reduction of human melanoma tumor growth in severe combined immunodeficient mice by passive transfer of antibodies induced by a high molecular weight melanoma-associated antigen mimotope vaccine,' new data in cancer...

Studies from University of Heidelberg, Department of Urology in the area of cancer gene therapy published.
January 12, 2009... Current study results from the report, 'Evaluation of cytotoxic effects induced by bcl-2 and bcl-xL antisense-oligodeoxynucleotides in normal urothelium and transitional cell carcinoma,' have been published. "We report on cytotoxic effects of...

Study data from Sun Yat-Sen University, Department of Gastroenterology update understanding of cancer gene therapy.
January 12, 2009... Data detailed in 'Specific reversal of MDR1/P-gp-dependent multidrug resistance by RNA interference in colon cancer cells' have been presented. According to a study from Guangzhou, People's Republic of China, "No control cell line was available...

New acute leukaemia findings from M. Mosor and co-authors described.(Report)
January 12, 2009... "DNA repair gene polymorphisms and mutations may influence cancer risk. The product of the NBS1 gene, nibrin, is functionally involved in the double-strand DNA break repair system," researchers in Poznan, Poland report (see also Acute...

Data from University of Bologna advance knowledge in acute myelogenous leukemia.
January 12, 2009... "To potentiate the response of acute myelogenous leukemia (AML) cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) cytotoxicity, we have examined the efficacy of a combination with perifosine, a novel...

New findings from J.E. Carter and co-authors describe advances in adenocarcinoma.
January 12, 2009... " The diagnosis of linitis plastica-type adenocarcinomas of the stomach has traditionally been made by brush cytology, and mucosal biopsy. These techniques may yield false negative results due to the often submucosal location of these lesions,"...

Few DNA repair genes maintain association with cancer in field synopsis.
January 19, 2009... Variants of numerous DNA repair genes initially appeared to be statistically significantly associated with cancer risk in epidemiological studies. When the data from individual studies are pooled, however, few DNA repair gene variants appear...

New insight into aggressive childhood cancer.
January 19, 2009... A new study reveals critical molecular mechanisms associated with the development and progression of human neuroblastoma, the most common cancer in young children. The research, published by Cell Press in the January 6th issue of the journal...

Research from University of Manchester broadens understanding of immunization.
January 19, 2009... According to a study from the United Kingdom, "We sent a questionnaire to 38% (1084) of 2817 parents whose daughters had been offered human papillomavirus vaccination and who had agreed to participate." "Of these, 60% (651) returned a...

Research results from G. Verdeil and colleagues update understanding of life sciences.
January 19, 2009... According to a study from the United States, "Because of mechanisms of self-tolerance, many tumor-specific CD8 T cells exhibit low avidity for tumor antigens and would benefit from strategies that enhance their numbers and effector function....

Riley Hospital Ranked Among Top Children's Hospitals in the Nation by Parents Magazine.
January 19, 2009... Parents magazine has released its annual ranking of children's hospitals recognizing Riley Hospital for Children's neonatal and pulmonary care departments in the top five nationally (see also Pediatrics). Riley Hospital was ranked among...

McGill researchers discover gene that increases susceptibility to Crohn's disease.
January 26, 2009... This release is available in French (see also McGill University). Researchers at McGill University, the Research Institute of the McGill University Health Centre (RI MUHC) and the McGill University and Genome Quebec Innovation Centre, along...

Research reports on cancer vaccines from Y.M. Saenger and colleagues provide new insights.
January 26, 2009... "Passive immunization with monoclonal antibody TA99 targeting melanoma differentiation antigen tyrosinase-related protein-1 (Tyrp1; gp75) and active immunization with plasmid DNA encoding altered Tyrp1 both mediate tumor immunity in the 1316...

Researchers at University of Notre Dame have published new data on cancer vaccines.(Report)
January 26, 2009... "Immunotherapy by vaccination represents a novel method for treatment of cancer. In this regard, vaccines with the broadest possible menu of relevant antigens stand the greatest chance of success," scientists in the United States report (see...

Researchers from University of Lubeck, Medical Department describe findings in cancer vaccines.
January 26, 2009... According to recent research from Lubeck, Germany, "Wood and colleagues present the results from a randomized phase III trial comparing adjuvant vitespen therapy with observation alone following nephrectomy for the treatment of kidney cancer....

Studies from University of Manchester further understanding of cancer vaccines.
January 26, 2009... According to recent research from Manchester, the United Kingdom, "We investigated the use of a therapeutic vaccine, TroVax in patients undergoing surgical resection of colorectal cancer liver metastases. Systemic immunity generated by...

How do cells count?
January 26, 2009... In the 13th January print edition of the journal Current Biology, Instituto Gubenkian de Ciencia researchers provide insight into an old mystery in cell biology, and offer up new clues to understanding cancer. Ines Cunha Ferreira and Monica...

Mobile phone use not associated with melanoma of the eye.
January 26, 2009... Mobile phone use is not associated with the risk of melanoma of the eye, researchers report in the January 13 online issue of the Journal of the National Cancer Institute (see also Journal of the National Cancer Institute). Although there...