Clinical Oncology Week articles from January 2003

Clinical Oncology Week archives from January 2003

Early resection appears to be appropriate treatment for extrahepatic cysts.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- Researchers in the Netherlands sought "to compare presentation, complications, diagnosis, and treatment of choledochal cysts in pediatric and adult patients. "Forty-two patients were analyzed...

Granulocyte colony-stimulating factor use may not affect survival.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- In a recent report, researchers in the United States sought "to determine whether granulocyte colony-stimulating factor (G-CSF) administered during acute myelogenous leukemia (AML) induction affects...

Pelvic lymph node debulking can benefit some patients with advanced disease.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- Researchers in Canada sought "to determine if a survival advantage exists from surgical debulking of enlarged pelvic lymph nodes in advanced cervical cancer. "Using information from studies...

Stromal invasion is most prognostic factor in survival.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- Researchers in Spain analyzed "the influence of tumor size and anatomopathological characteristics in the prognosis of patients with early-stage cancer of the uterine cervix treated with radical...

Two cases found after insertion of a Mirena IUCD.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from England, "the case histories of two patients who developed endometrial adenocarcinoma with a Mirena intrauterine system (IUS) in place are reported. "Two patients...

Isoverbascoside-treated gastric cancer cells show decreased proliferation.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- In a recent report, researchers in China investigated "the effects of phenylpropanoid glycoside antioxidant isoverbascoside on cell proliferation and differentiation of human gastric cancer cell line...

Laboratory studies in gynecologic oncology patients important.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "Arterial thrombosis is an extremely rare complication in gynecologic oncology with only two cases previously reported in the literature. Presentation, evaluation, and treatment varied considerably in...

Conservative management with primary chemoradiation may be successful.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "optimal management of carcinoma of the Bartholin gland is not yet defined. Patients with locally advanced disease have historically been managed...

Cellular differentiation important for diagnosis in rare disease.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from Japan, "the cytologic appearance of basaloid squamous carcinoma (BSC) arising in the lower respiratory tract has not been described very well because of its rarity. This...

Researchers make case for eliminating term "Incidentaloma".
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "The concept of the incidentaloma, a totally asymptomatic nonfunctional tumor that is clinically and biochemically silent and discovered incidentally in a totally asymptomatic patient, is a byproduct...

Second transurethral resection often finds residual disease.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- Researchers in the United States evaluated "the impact of a second transurethral resection (TUR) on the pathologic stage in a unique patient population with T1 tumors. "Seventy-one patients with...

Smoking, not consumption of fruits, vegetables associated with disease.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, researchers "examined the relation between dietary fruit and vegetables, carotenoids and vitamin intakes, and the risk of bladder cancer among male...

Recombinant human melanotransferrin may work as drug delivery to brain.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from Canada, "the blood-brain barrier (BBB) performs a neuroprotective function by tightly controlling access to the brain; consequently it also impedes access of proteins...

Analysis of cognitive deficits in children help identify interventions.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- In a recent study, researchers in Denmark sought to described "cognitive function and to evaluate the association between potentially predictive factors and cognitive outcome in an unselected...

Progesterone may be involved in regulation of neurogenic tumors.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from Japan, "progesterone has been suggested to be involved in the functions of the nervous system, but it has yet to be examined in humans. "Progesterone has also...

Cytology may help identify patients in need of aggressive treatment.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- In a recent report, researchers in Italy described "the cytologic features of invasive micropapillary carcinoma of the breast, a distinct, unusual variant of infiltrating duct carcinoma. "It is...

Immunocytochemical staining for receptors shows promise.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- In a recent report, researchers in Japan investigated "estrogen receptor (ER) and progesterone receptor (PR) levels in imprint specimens obtained at breast surgery and to compare their correlation with...

Lymphedema can impact quality of life in survivors of early-stage disease.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "the standard of care for early-stage breast cancer includes surgical removal of the tumor and axillary lymph node dissection (ALND). Despite...

Oxidative stress gives tumor cells growth advantage over normal cells.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from India, "the increasing global incidence of breast cancer emphasizes the need to understand the various mechanisms involved in breast tumorigenesis. The present study...

Trends indicate westernization of lifestyles increases incidence.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from the Peoples Republic of China, "Hong Kong has the highest breast cancer incidence in Asia and studying secular changes in its rates may lead to hypotheses regarding...

Smoking enhances asbestos-induced genotoxicity.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "Several experimental and epidemiological studies have indicated augmentation of asbestos-induced diseases by cigarette smoke by mechanisms which are still unknown. To determine whether smoking...

Bone marrow stromal cell line assesses p53 responses to genotoxic stress.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "the p53 protein is widely regarded as an important sensor of genotoxic damage in cells, and mutations in p53 are the most frequent observed in human...

Whole-body PET scan can help determine primary tumor.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- In a recent study, researchers in Denmark sought "to demonstrate the efficacy of whole-body 18F-fluoro-2-deoxy-D-glucose positron emission tomography (18F-FDG PET) in the detection of a carcinoma of...

Fine needle aspiration important when used with color Doppler findings.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- Recently, researchers in Iran described "the cytologic findings in 13 cases of carotid body tumors (CBTs) and discuss the differential diagnoses. "Cytologic smears were obtained from 13 cases of...

Number of screenings over-reported by ethnic women.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "screening mammogram and Pap smear rates are lower for women in underserved racial and ethnic groups, yet may be overestimated due to reliance on...

Immunophenotyping may be helpful in diagnosis of cervical masses.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "cervical thymoma is a rare entity. To our knowledge, this is the 20th reported case of cervical thymoma and the fourth case of fine needle...

Chimeric receptor appears to augment T cell immunity against tumors.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from Australia, "a new strategy to improve the therapeutic utility of redirected T cells for cancer involves the development of novel antigen specific chimeric receptors capable of...

Hepatic resection for colorectal metastases safe, predicts outcomes.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from Norway, "a retrospective study was performed to define patient selection, safety, and efficacy of hepatic resection for colorectal metastases. "The recently...

Phytoestrogens may play role in progression of malignancy.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from Austria, "soybean products are highly represented in the traditional Asian diet. Major components of soy proteins are phytoestrogens, such as isoflavones. They may...

Telomerase catalytic subunit mRNA may be useful in diagnosing.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- Researchers in the United States investigated "the role of reverse transcriptase polymerase chain reaction (RT-PCR) in determining telomerase catalytic subunit (hTERT) mRNA to assist with the diagnosis...

Virtual test can detect colorectal polyps and cancers.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to researchers from Peoples Republic of China, they assessed "the sensitivity of virtual colonoscopy in detecting colorectal polyps and cancers in a Chinese population. "Seventy-one...

Computed tomographic findings of liver metastases predictive of recurrence.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from Japan, "the pathologic mode of infiltrative growth (infiltrative [INF]-alpha, INF-beta, and INF-gamma) of colorectal liver metastases had characteristic morphologic...

Fourteen-day rule shortens time to specialist.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- In a recent report, researchers in England examined "the effect of the 14-day rule on the colorectal service of a district general hospital." The researchers conducted a "prospective audit of all...

Infusion chemotherapy, hepatectomy may help with unresectable metastases.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to researchers in Japan, "the aim of this study was to assess the value of aggressively treating patients with unresectable liver metastases from colorectal cancer and a poor prognosis. ...

Laminin-5 gamma 2 chain expression can be a poor prognostic indicator.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from Japan, "the laminin-5 gamma2 chain plays an important role in cell migration during tumor invasion and tissue remodeling. Although this chain has been reported to be...

Researchers find consistent dose response to red meat consumption.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from England, "N-Nitroso compounds are found in the colon and are formed endogenously because amines and amides are produced by bacterial decarboxylation of amino acids in the...

Trans-signalling via the agonistic soluble IL-6 receptor in human diseases.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "The activation of cells that do not express the membrane bound interleukin-6 receptor (IL-6R) by IL-6 and the soluble IL-6 receptor (sIL-6R) is termed trans-signalling. Trans-signalling may be a...

Software tools for high throughput analysis of tissue microarrays.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "The creation of tissue microarrays (TMAs) allows for the rapid immunohistochemical analysis of thousands of tissue samples, with numerous different...

Scientists call for more research on diet, obesity and reflux risk factors.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "incidence rates for esophageal adenocarcinoma have increased over 350% since the mid-1970s. Rates for gastric cardia adenocarcinoma have also...

Multiplex PCR assay is better test of bcl-2/JH fusion sequences.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "Follicular lymphoma (FL) is characterized by the presence of the t(14;18)(q32;q2l) chromosomal translocation which juxtaposes the bcl-2 gene at 18q21 with the immunoglobulin heavy chain locus at...

Radical resection improves the survival in elderly patients.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from Japan, "Radical resections have been reported to improve the surgical outcome for patients with carcinoma of the gallbladder. In recent years surgeons have had...

Anti-ulcer drug, geranylgeranylacetone, may have protective role.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "Geranylgeranylacetone (GGA) is an antigastritis and antiulcer agent, with as yet an unknown mechanism of action. In this study, we investigated the effect of GGA on Helicobacter pylori-induced...

Interferon-gamma regulates injury by releasing TNF receptors.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from Japan, "interferon (IFN)-gamma and tumor necrosis factor (TNF) are predominant cytokines produced in the gastric mucosa of patients with Helicobacter pylori-infected...

Genomic hybridization distinguish long-term from typical survivors.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "Glioblastoma (GBM) remains a highly lethal neoplasm, refractory to current therapies. The molecular genetic aberrations most closely related to clinical...

P-glycoprotein is important obstacle preventing paclitaxel entry into brain.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from Germany, "Paclitaxel concentrations in the brain are very low after intravenous injection. Since paclitaxel is excluded from some tumors by p-glycoprotein (p-gp), the...

Genomic hybridization indicates cyclin L may be candidate oncogene.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from France, "DNA gains targeting the 3q chromosome are common in head and neck squamous cell carcinomas, as well as in lung, ovarian, and cervical cancer. Several...

Acitretin may be useful for prophylaxis of cutaneous malignancies.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "Heart transplant recipients have an increased risk of developing actinic keratoses and nonmelanotic skin cancers when compared with the general population. Systemic retinoids have been shown to be...

Rates of liver cancer, hepatitis B and C increase.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "To provide information on poorly described Canadian hepatocellular cancer epidemiology, researchers in Canada analyzed incident cases abstracted from the Canadian Cancer Registration Database...

X-ray screening for second primary lung cancer does not improve survival.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from Netherlands, "As a result of smoking, patients who have received curative treatment for laryngeal cancer run a high risk of developing lung cancer. Therefore, these patients...

Precursors of leukemic dendritic cells are identified.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from France, "dendritic cells (DC) can facilitate immune responses that might help in the induction of effective antitumor T cell responses. We reported previously that...

Researchers analyze susceptibility to NKG2D-dependent natural killer cells.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from Italy, "NKG2D, together with NKp46 and NKp30, represents a major triggering receptor involved in the induction of cytotoxicity by both resting and activated human...

Researchers identify clone-specific markers at birth in children with ALL.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from Denmark, "recent studies have suggested that development of childhood acute lymphoblastic leukemia may often be initiated in utero. To provide further evidence of an prenatal...

P53 mutation is source of aberrant beta-catenin in cancer cells.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from Turkey, "beta-catenin is involved in both cell to cell interactions and wnt pathway-dependent cell fate determination through its interactions with E-cadherin and...

Pretreatment status of AFP-L3 could be considered a useful marker.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from South Korea, "lens culinaris agglutinin-reactive alpha-fetoprotein (AFP-L3) is known to be a useful marker for the diagnosis of hepatocellular carcinoma (HCC). Recent...

Prognostic assessment and evaluation of the benefits of treatment.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "Prognosis estimation in patients with hepatocellular carcinoma (HCC) can provide information at diagnosis and can indicate therapy. Because cirrhosis underlies HCC in most individuals, their outcome...

Prognostic index created for patients treated by percutaneous ethanol injection.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from Japan, "Percutaneous ethanol injection (PEI) has been widely performed and is now accepted as a viable alternative to hepatic resection in patients with small...

Accelerated hypofractionation therapy appears to be safe.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- Researchers in Canada sought "to describe the outcome of treating early-stage non-small-cell lung cancer (NSCLC) with an accelerated hypofractionated course of radiotherapy. "A policy of treating...

Asbestos bodies in the sputum may be long-term marker for exposure.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "A cross-sectional medical survey including collection of three consecutive sputum samples was carried out among 270 retired workers of a textile and friction materials factory, in order to investigate...

Involved-field radiotherapy can limit toxicity.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- In a recent report, researchers in the Netherlands sought "to establish the recurrence patterns when elective mediastinal irradiation was omitted, patients with Stage III non-small-cell lung cancer...

No link to isocyanate-exposed employment found in factory workers.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- Recently, researchers in England sought "to describe cause-specific mortality and site-specific cancer morbidity among workers employed in factories that produce polyurethane foams, and to determine if...

p53 codon 72 Arg homozygosity is associated with advanced lung cancer.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "The association of p53 codon 72 polymorphism with cancer has been investigated by several scientific groups with controversial results. In the present study, we examined the genotypic frequency of...

Multicolor-FISH analysis of a natural killer cell line (NK-92).
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "Relatively little is known about the cytogenetics of natural killer (NK) neoplasms, and the emergence of recurrent structural alterations involving specific chromosomal breakpoints is still in its...

Local delivery of mitoxantrone effective as treatment in rats.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "Mitoxantrone is a drug with potent in vitro activity against malignant brain tumor cell lines; however, its effectiveness as a systemic agent has been hampered by poor central nervous system...

Autopsy report shows a clinically unsuspected tumor.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from Brazil, "Struma Ovarii represents less than 3% of ovarian teratomas. The malignant counterpart is very rare. A 67-year-old woman with ascites and progressive weight loss...

Silver intensification useful for diagnosis in female genital organs.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- Researchers in Japan conducted a study "to improve the procedure for diagnosing vaginal melanoma with cytopathologic analysis of HMB-45. "The study examined silver intensification of immunostaining...

Different subtypes may be important in screening and treatment.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from Israel, "Ionizing radiation is the only established risk factor recognized today in the causation of meningioma. The aim of the present report is to describe the demographic...

Rare neoplasm should be considered when aspirating inguinal lymph nodes.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "Intranodal myofibroblastoma is a rare, primitive, mesenchymal neoplasm of the lymph nodes first described in 1989. It behaves in a benign fashion and has a great predilection for the inguinal region....

Determination of cyclin D1 and CD20 mRNA levels by real-time RT-PCR.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "Cyclin D1 overexpression is a valuable marker for the diagnosis of mantle cell lymphoma (MCL). We used a real-time quantitative reverse...

Phosphomonoesters/nucleotide triphosphates ratios may predict outcomes.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "This review describes problems and solutions encountered in large scale multicenter trials of magnetic resonance methods for monitoring cancer. It is illustrated with reference to the...

Limited resection may be appropriate in branch duct types.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "One of the main problems in the management and treatment of intraductal papillary-mucinous tumors is the lack of a reliable predictive factor for malignancy." Researchers in France hypothesized...

Study indicates NGF can act in paracrine and/or autocrine manner.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from Germany, "Nerve growth factor (NGF) exerts both stimulatory and inhibitory effects on neuronal and certain non-neuronal tumors. In pancreatic cancer NGF is...

Fine needle aspiration cytology can diagnose disease but pitfalls remain.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- Researchers in Japan conducted a study "to elucidate the specific cytomorphologic patterns and diagnostic pitfalls in fine needle aspiration cytology (FNAC) of parathyroid lesions. "Seventy-two...

Test soundly measures patient preferences for treatment options.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "The purpose of this study was to develop a patient-centered measure of treatment preference applicable across a range of diseases and treatment decisions," researchers in the United States report. ...

Can care demand be reduced through more effective health promotion?
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from England, "The cost of health care continues to rise in the face of an apparently insatiable demand. Unless the actual need for health care can be reduced to...

MR cholangiopancreatography, sectional MR imaging help determine origins.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from South Korea, "periampullary carcinomas arise within 2 cm of the major duodenal papilla and comprise carcinomas of the ampulla, distal common bile duct, pancreas, and duodenum....

Choroidal metastases found in elderly man.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- In a recent study, researchers in the United States described "a 71-year-old man with bilateral primary adrenal lymphoma with metastases to the choroids. "A 71-year-old man presented with decreased...

Characterization of epithelial senescence may help identify cancer genes.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "Evasion of cellular senescence is required for the immortal phenotype of tumor cells. The tumor suppressor genes p16(INK4A), pRb, and p53 have been implicated in the induction of cellular senescence....

Flaxseed supplementation inhibits tumor growth in transgenic mice.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- In a recent study, researchers in the United States investigated "the effects of flaxseed supplementation on prostatic neoplasia in the transgenic adenocarcinoma mouse prostate (TRAMP) model. "A...

Mitogen-activated protein kinase plays role in apoptosis.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from Japan, "the synthetic retinoid N-(4-hydroxyphenyl)retinamide (4-HPR) has been shown to induce apoptosis in various types of tumors, including prostate cancer. "We sought...

Prostate-specific antigen testing appears to improve survival.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- In a recent study, researchers in the United States sought "to determine how the implementation of prostate-specific antigen (PSA) testing has affected disease-specific survival and other...

TRAP-Mediator complex may play coregulatory role in androgen receptor-mediated gene expression.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "The human thyroid hormone receptor associated protein (TRAP)-Mediator complex was originally identified as a large multimeric complex that copurifies with the thyroid hormone receptor (TR) from HeLa...

Transdifferentiation of prostatic stromal cells decreases growth inhibitors.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "Age-related development of benign prostatic hyperplasia is an important health issue in developed countries. The histopathogenetic hallmark of this disease is the increase in relative and absolute...

Complication rate similar for patients with benign or cancerous lesions.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from England, "a number of studies have shown that the early mortality following TURP [transurethral resection of prostate] is higher for patients with prostate cancer than...

External irradiation effective in achieving cure rates.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- Researchers in the United States studied "the biochemical cure rates (biochemically no evidence of disease) after external irradiation (RT) in patients with high-risk prostate cancer after radical...