Clinical Oncology Week articles from December 2004

Clinical Oncology Week archives from December 2004

Enhancing cancerous area on MR mammography compared with pathological exam.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- According to a study from Belgium, "The enhancing area surrounding breast carcinoma on magnetic resonance (MR) mammography is correlated with findings from pathological examination. "We studied 194...

New surgical technique determines if cancer has spread.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Women in Britain with breast cancer will soon benefit from a pioneering surgical technique developed in Wales. Robert Mansel and his team at Cardiff University, Wales College of Medicine, recently...

Phage display library from lymph nodes of breast cancer patients constructed.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Researchers have constructed phage display libraries from reactive lymph nodes of breast carcinoma patients. According to a study from Germany, "The display of recombinant antibody fragments on the...

Novel genes linked to 5-FU resistance identified in gastric tumor cells.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- A number of gastric tumor genes have been linked to 5-fluorouracil (5-FU) resistance. In a recent study from South Korea, conducted to "identify novel genes associated with 5-FU in gastric cancer,"...

Inflammatory responses in cervical neoplasia suppressed in HIV-positive women.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Inflammatory responses in cervical intraepithelial neoplasia are suppressed in HIV-positive women. "The role of mucosal immunity in human papillomavirus (HPV)-related cervical diseases is poorly...

Trial compares docetaxel to paclitaxel for first-line treatment of cancer.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- The combination of docetaxel and carboplatin for first-line treatment of ovarian cancer appears to result in similar rates of survival compared with the current standard, paclitaxel and carboplatin,...

CE Mark issued for AlzheimAlert Test Kit making it available in European Union.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Nymox Pharmaceutical Corporation (NYMX) announced the certification of its AlzheimAlert test kit with a CE Mark, making the device eligible for sale in the European Union. The company announced...

Cancer reference laboratory named to Deloitte's Fast 500 list.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- US LABS announced that it has ranked 181 on the 2004 Deloitte Technology Fast 500, a ranking of the 500 fastest-growing technology companies in North America. The company also ranked sixth on the...

Scott Hawley named American Cancer Society research professor, awarded $300,000.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Scott Hawley, PhD, investigator at the Stowers Institute for Medical Research, has been named an American Cancer Society (The Society) Research Professor. The designation carries an award of $300,000...

Promising data presented on phase 2 trial drug for superficial bladder cancer.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Spectrum Pharmaceuticals, Inc. (SPPI) announced encouraging efficacy and safety data from the ongoing multi-center phase 2 trial of EOquin as a single agent in patients with recurrent superficial...

Trisacryl gelatin microspheres effective for preoperative embolization.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Trisacryl gelatin microspheres are highly effective for embolization of bone neoplasms prior to surgical removal. Radiologists in Austria conducted a study "to compare the efficacy of trisacryl...

Post-therapy damage in medulloblastoma patients can be mistaken for new tumors.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Irradiation and high-dose chemotherapy used to treat two types of brain tumors - medulloblastoma and supratentorial PNET - can cause changes in the brain's white matter that look like tumors when seen...

"Knowledge management" system could "revolutionize" treatment.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Scientists in the U.K. have designed a knowledge management system that they think could enable medical practitioners to make speedy, informed decisions about breast cancer patients. The project...

Accelerated partial breast irradiation new option for breast cancer patients.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Women diagnosed with breast cancer must weigh the options between old tried- and-true and next-generation breast cancer treatments An estimated 216,000 American women will be diagnosed with breast...

Apoptotic response of tamoxifen-resistant breast tumor cells clarified.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Expression of apoptosis-related genes has been characterized in tamoxifen (TAM)-resistant breast tumor cells. In a recent study, oncologists in Germany "examined alterations in the apoptotic...

Chemotherapies have varied effects on menopausal symptoms of cancer patients.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Oncologists in Belgium have studied "the changes in frequency and severity of menopausal symptoms in patients receiving tamoxifen or aromatase inhibitors and identified factors influencing these...

Data on radiation dose from digital mammography reported from large study.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Radiologists in Spain have reported the mean and range of radiation dose from digital mammography calculated from data on over 5,000 patients. M. Chevalier, of the University of Complutense Madrid,...

Elizabeth Edwards's diagnosis encourages others to get check-ups.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Elizabeth Edwards said she is glad her breast cancer diagnosis is encouraging people to stop neglecting their own health, as she admits she did. "I didn't test myself as often," and didn't get...

Genes linked to breast tumor progression and/or metastasis identified.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- A number of novel breast tumor genes linked to progressive disease and/or metastasis have been identified. "Breast carcinoma is a complex disease characterized by accumulation of multiple genetic...

HER2-positive disease invades organs due to fatal chemical attraction.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Researchers at The University of Texas M.D. Anderson Cancer Center have solved the mystery of why an aggressive form of HER2-positive breast cancer travels readily to a few key organs - lungs, liver,...

Hierarchical clustering of breast tumor immunomarkers has high prognostic value.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Hierarchical clustering analysis of breast tumor immunohistochemical data has high prognostic value. "Prognostically relevant cluster groups, based on gene expression profiles, have been recently...

In BRCA1/2 mutation carriers, cancer may mimic benign lesions on mammogram.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- A study involving BRCA 1/2 gene mutation carriers found that a significant number of circumscribed non-calcified mammographic masses found in these patients were malignant. "Breast cancers in gene...

Patients receiving taxane-based chemotherapy not at higher risk of pneumonitis.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Researchers at The University of Texas M.D. Anderson Cancer Center have shown that breast cancer patients treated with taxane-based chemotherapies and radiation are not at increased risk of developing...

Plasma prolactin levels associated with increased postmenopausal disease risk.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Study findings suggest that plasma prolactin levels are associated with increased postmenopausal risk of breast cancer. "Prolactin is important in human breast development, and substantial...

Private practice in Munich, Germany, selects mammography system.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- A new private practice in Munich, Germany, has chosen Sectra's revolutionary digital mammography system, Sectra MicroDose Mammography. The new practice will focus on the low-dose concept and will...

Saudi Arabia: National guidelines on breast cancer management needed.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Data revealing variability and/or deficiencies in breast cancer management among surgeons and hospitals in Saudi Arabia have at least one group of surgeons there calling for national guidelines to set...

Topoisomerase II alpha is a prognostic indicator in breast cancer.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Topoisomerase II alpha is a prognostic indicator in breast cancer, pathologists at Tel Aviv University report. "Topoisomerase II-alpha (Topo II-alpha) is a nuclear enzyme. Its expression rises...

Trial evaluates supplemental screening sonography in dense breasts.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- A clinical trial is evaluating use of supplemental screening sonography to detect cancer in dense breasts. "In single-center trials across 42,838 examinations, 150 (0.35%) cancers were identified...

Women willing to deal with negative aspects of screening to gain benefit.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- There is nothing pleasant about getting a mammogram done, but overall, women are willing to put up with the discomfort and potential anxiety for the benefit of early detection of breast cancer. ...

Biopharma reports third quarter 2004 results, clinical achievements.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Progenics Pharmaceuticals, Inc., (NASDAQ: PGNX) announced its results of operations for the third quarter ended September 30, 2004, and for the first 9 months of 2004. Revenues for the third...

Biopharmaceuticals company announces third quarter results, progress made.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Keryx Biopharmaceuticals announced its financial results for the third quarter ended Sept. 30, 2004. At Sept. 30, 2004, Keryx announced cash, cash equivalents, interest receivable and investment...

Biotech company announces restructured agreement for cancer drug.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Ligand Pharmaceuticals announced that it has restructured its agreement with Eli Lilly and Company with respect to the royalties payable to Lilly on sales of Ligand's marketed cancer drug Ontak...

Dermatology pharmaceutical company announces financing, new hires.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Neosil Incorporated announced that it closed a $32 million placement of series A Preferred Stock to a group of investors led by MPM Capital and Burrill & Company. The financing will enable Neosil...

Developer of surgical and diagnostic products announces financial results.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Neoprobe Corporation (OTCBB:NEOP) announced consolidated operating results for the third quarter of 2004. Third quarter results included revenues of $1.7 million, representing increases of 46%...

Biotech establishes new business units for pain and oncology.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Ligand Pharmaceuticals announced that it has established separate therapeutically focused business units for its pain and oncology products. Patrick M. Shea, formerly vice president of marketing,...

IUN and Theragenics Corporation sign 3-year strategic alliance agreement.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- International Physician Networks dba International Urology Network (IUN) has entered into a 3-year exclusive, strategic alliance agreement with Theragenics Corporation (TGX). This agreement will...

Molecular diagnostics company announces expansion of diagnostic pipeline.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Third Wave Technologies Inc. (TWTI) provided new details about the expansion of the company's molecular diagnostic pipeline and issued preliminary guidance for 2005 clinical molecular diagnostic...

Vascular targeting agent, radiation reduces tumor growth by 98% in animals study.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Peregrine Pharmaceuticals, Inc. (PPHM) announced that Philip Thorpe, PhD, a member of its scientific advisory board, gave the keynote presentation at the Vascular Targeting Agents conference in...

Hepatitis C infection encourages liver cancer recurrence after resection.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Hepatitis C infection encourages liver cancer recurrence after resection. "Hepatocellular carcinoma (HCC) is closely associated with chronic hepatitis B or C virus (HBV, HCV) infection. Tumor...

OC Auto Micro 80 analyzer detects blood in stool samples.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Polymedco, Inc., has announced the addition of a new analyzer to their existing offering of automated testing platforms. The OC Auto Micro 80 analyzer processes a new, FDA-cleared immunochemical test to...

Program to implement required Pap interpretation proficiency testing announced.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Women will soon begin to have added assurance that the medical professionals who read their Pap tests are qualified to do so. The "added assurance" will be provided by a nationwide proficiency test...

European cancer organization offers guidelines for treating anemia.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- New European Organization for Research and Treatment of Cancer (EORTC) guidelines aim to assist physicians in managing anemia more effectively in their patients with cancer by providing advice on the...

Radiation therapy systems selected to supply Wave 7 of UK Cancer Plan.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Varian Medical Systems, Inc. (VAR), U.K. developer of radiation therapy systems, will be supplying 7 new linear accelerators to 4 U.K. radiotherapy centers in the newest wave of the Department of...

Skin cancer study using MedPulser Electroporation Therapy system begins.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Genetronics Biomedical Corp. (GEB), a late-stage developer of oncology and other therapies using electroporation, has begun treating skin cancers in patients with primary and recurrent solid tumors...

Expression of the cell surface mucin gene family in adenocarcinomas reported.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Scientists report the expression of the cell surface mucin gene family in adenocarcinomas in a recent issue of the International Journal of Oncology. According to recent research from Australia,...

Tumor vaccine therapy reviewed.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Researchers review tumor vaccine therapy in a recent issue of Blood. According to published research from the United States, "Fusion proteins containing chemokine receptor ligands have been used to...

Addition of INTEGRILIN provides superior platelet inhibition with stenting.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Millennium Pharmaceuticals, Inc., (NASDAQ:MLNM) announced that in the Clopidogrel Loading with Eptifibatide to Arrest the Reactivity of Platelets (CLEAR Platelets) trial, the addition of INTEGRILIN, a...

Biopharma company's cell cycle inhibitor work published in Science.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Cyclacel Group plc, a U.K.-based biopharmaceutical company, announced that the editor of Science magazine cited a chemistry paper by Cyclacel scientists regarding its CYC103 targeted drug discovery...

Chemoradiation with gemcitabine an alternative for patients with renal failure.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Chemoradiation with gemcitabine is an alternative for patients with renal failure when cisplatin-based therapy is contraindicated, study results indicate. L. Cetina and colleagues, National...

HPV 16 infection a risk factor for disease progression in younger women.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Infection with human papillomavirus 16 infection is a significant risk factor for cervical cancer progression in younger women, study data indicate. "Human papillomaviruses (HPV), particularly type...

Small cell neuroendocrine carcinomas of the uterine cervix characterized.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Pathologists with Yamagata University, Japan, recently characterized small cell neuroendocrine carcinomas of the uterine cervix. G.M. Ishida and colleagues stated, "Small cell carcinomas of the...

Study: Shorter, more aggressive treatments better control disease.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Women receiving care at small, local radiation therapy facilities are less likely to receive shorter, more aggressive treatments for their cervical cancer, according to a study by M.D. Anderson Cancer...

IMPAC announces support for CMS quality of care assessment in chemotherapy.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- IMPAC Medical Systems, Inc., (IMPCE) announced its support for the U.S. Center for Medicare & Medicaid Services (CMS) 1-year demonstration project to assess the quality of care for cancer patients...

Primary endpoint achieved in phase 3 trial of genasense plus chemotherapy.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Genta Incorporated (NASDAQ:GNTA) announced that the company's randomized phase 3 clinical trial of Genasense (oblimersen sodium) Injection in patients with relapsed or refractory chronic lymphocytic...

Affitech, Peregrine expand collaboration to develop new fully human antibodies.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- [lw2][pb2][uw2][vw2] (carol for Heather) Peregrine Pharmaceuticals Julie Marshall, +1-800-987-8256 Peregrine Pharmaceuticals, Inc., (NASDAQ:PPHM) and Affitech AS recently announced that they have...

Anti-cancer vaccine R&D agreement signed.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- IDM (Immuno-Designed Molecules) announced the signing of a research and development agreement with the Walter Reed Army Institute of Research involving the development of an anti-cancer vaccine...

Biopharma, consortium collaborate to treat brain cancer patients.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- [qw2][uw2][bb2][pb2] (carol for Heather) Peregrine Pharmaceuticals Julie Marshall, +1-800-987-8256, or info@hawkassociates.com Peregrine Pharmaceuticals, Inc., (NASDAQ:PPHM) has entered into a...

Companies combine technologies to search for cancer-fighting compounds.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Tripos, Inc. (TRPS), and NovaScreen Biosciences Corporation have announced a collaboration to provide a drug discovery solution to Strida Pharma Inc. for its cancer therapeutics development program...

Companies introduce solid support product for manufacture of oligonucleotides.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Nitto Denko Corporation, a polymer company, and Isis Pharmaceuticals, Inc. (ISIS), a RNA-based drug discovery and development company, have jointly developed a new solid support for the manufacture of...

DNA-based diagnostics company, biotech products provider announce partnership.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Tm Bioscience Corporation (TMC), a diagnostics company in the commercial genetic testing market, has signed a development and supply agreement with Genzyme Corporation, a provider of biotechnology...

Genetic markers of tumorogenic aberrant crypt foci identified.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Genetic markers of tumorogenic aberrant crypt foci (ACF) have been identified in a murine marker of colon cancer. In a recent study from the United States, conducted to "determine whether cancer...

Lipoxin may provide a promising new oral treatment for Crohn disease.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Berlex (NYSE:SHR) announced that new laboratory results demonstrate that its modified version of the naturally occurring lipoxin molecule exerts potent anti-inflammatory and immunomodulatory effects in...

Atomic structure of enzyme HSD-1 reported, use in diabetes treatment studied.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Syrrx Inc., a structure-based drug discovery company, reported the publication of the atomic structure of human 11(beta)-hydroxysteroid dehydrogenase type-1 (HSD-1). HSD-1 inhibitors are being...

Indian pharmaceutical company launches new cancer diagnostic product.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Indian pharmaceutical company J.B. Chemicals & Pharmaceuticals launched a high-tech diagnostic product used for angiographies, neurological diseases and diagnosis of cancer patients. The company...

Multiplex RT-PCR assay detects balanced translocations in leukemia patients.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- A multiplex RT-PCR assay detects balanced translocations in leukemia patients. "The upfront application of molecular methods for identifying the fusion transcripts arising from balanced...

Dietary fiber supplement can reduce drug use for high cholesterol, study shows.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Researchers from the University of Medicine and Dentistry (UMDNJ), Robert Wood Johnson Medical School, announced results of a study that shows giving a psyllium supplement to patients taking simvastatin...

Elderly cancer patients significantly underrepresented in cancer trials.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- A new study finds that only 36% of cancer patients ages 65 and older participate in clinical trials, despite making up 60% of the U.S. cancer population. The study was published in the Journal of...

Novartis picks drug for development from protein kinase research collaboration.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Vertex Pharmaceuticals Incorporated (VRTX) announced that Novartis has selected a small molecule protein kinase inhibitor, VX-322, from Vertex for clinical development for the treatment of cancer. ...

Recent advances in endometriosis highlighted.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- A recent article reviewed "recent advances in our understanding of endometriosis with special reference to its pathogenesis, recent molecular studies, and relationship to neoplasia." According to...

PinX1 may regulate telomere length in human hepatocellular carcinoma.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- PinX1 may regulate telomere length in human hepatocellular carcinoma. "PinX1 is located at 8p23, a region with frequent loss of heterozygosity in hepatocellular carcinomas (HCCs). Overexpression of...

Biopharm company focused on protein-deficiency disease reports Q3 results.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Transkaryotic Therapies, Inc. (TKTX) announced its consolidated financial results for the 3 and 9 months ending September 30, 2004. Total sales of Replagal (agalsidase alfa), TKT's enzyme...

Offer made to skin care company shareholders to raise funds for clinical trials.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Peplin Limited (PEP) announced an offer to shareholders to raise $10.2 million to fund the first phase 2 clinical trials for its proprietary skin cancer product PEP005 Topical. The renounceable...

Oncology company announces effectiveness of S-3 Registration Statement.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- ImClone Systems Incorporated (IMCL) announced that as of 5:00 pm Eastern Standard Time on November 5, 2004, the U.S. Securities and Exchange Commission declared that the Registration Statement of...

Oncology-focused biopharmacology company reports third quarter financials.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Cell Therapeutics, Inc. (CTI) reported financial results for the third quarter ended September 30, 2004. Total revenues for the quarter were $8.7 million compared to $6.5 million in the third quarter of...

Pharmaceutical company reports third quarter revenue increase of 58%.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Ligand Pharmaceuticals reported record net product sales for the third quarter ended Sept. 30, 2004, of $44.7 million, compared to $28.1 million the third quarter of 2003, an increase of 59% driven by...

Therapeutics developer announces third quarter 2004 financial results.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Nuvelo, Inc. (NUVO) announced results for the quarter ended September 30, 2004. For the 3 months ended September 30, 2004, Nuvelo reported a net loss of $10.9 million or $0.34 per share compared to...

Bridge financing for phase 2 trial on blood substitute set, phase 3 funds sought.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Synthetic Blood International, Inc. (SYBD) has received bridge financing from overseas investors that is expected to be sufficient to fund operations, including the initiation of the company's first...

Specificity proteins are linked to the angiogenesis of pancreatic cancer.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Specificity proteins are linked to the angiogenesis of pancreatic cancer. "Sp proteins play an important role in angiogenesis and growth of cancer cells, and specificity protein 1 (Sp1) has been...

U.S. Patent Office reissues patent for in vivo optical imaging for whole animals.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Xenogen Corporation (XGEN), maker of advanced imaging technology to accelerate drug discovery and development, announced that the U.S. Patent and Trademark Office (USPTO) has reissued a patent on its...

Silenced heat shock protein 27 discourages prostate cancer progression.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Silenced heat shock protein 27 discourages prostate cancer progression. According to recent research published in the journal Cancer Research, "heat shock protein 27 (Hsp27) is a chaperone...

Antibody-drug conjugate collaboration expanded.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Seattle Genetics, Inc. (SGEN) announced that Genentech, Inc. (DNA) has agreed to pay a technology access fee of $1.6 million to designate additional antigen targets under the parties' existing...

Hyaluronan synthase 1 expression associates with ovarian cancer progression.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Hyaluronan synthase 1 expression associates with ovarian cancer progression. According to a study from Japan, "to determine if the immunohistochemical expression of hyaluronan synthase (HAS)...

Monoclonal antibody among HIV therapies discussed at human virology meeting.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Tanox, Inc. (TNOX) medical director Stanley Lewis recently presented findings from the phase 1 clinical trial of TNX-355 for the treatment of human immunodeficiency virus (HIV) at the 2004 International...

Advexin with chemotherapy promotes head and neck cancer cell death in studies.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Introgen Therapeutics, Inc., (INGN) announced the publication of data from preclinical studies evaluating the impact of Advexin in combination with chemotherapy (docetaxel) on head and neck cancer tumor...