Clinical Oncology Week articles from August 2003

Clinical Oncology Week archives from August 2003

Dose reductions can improve 5-FU toxicity and avoid treatment delays.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Dose reductions can improve 5-FU toxicity and avoid treatment delays. "This study used a prospectively managed clinical database in order to identify 1470 patients with gastrointestinal cancers...

Mortality from new lung cancer is high even after 5 disease-free years.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Mortality from new lung cancer is high even after 5 disease-free years "Among patients with non-small-cell lung cancer (NSCLC), those with pathological stage I have the best expectation of survival;...

Researchers give prophylactic options in patients with 5-FU cardiotoxicity.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Researchers give prophylactic options in patients with 5-FU cardiotoxicity. "At present, the various mechanisms involved in 5-fluorouracil (5-FU)-correlated cardiotoxicity remain to be elucidated...

NSAIDs may protect against colon, rectal, stomach, and ovarian cancer.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- NSAIDs may protect against colon, rectal, stomach, and ovarian cancer. According to a study from Denmark, "There is increasing evidence of an inverse association between use of nonsteroidal...

Postoperative calcitonin level and tumor extension are critical prognostic factors.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Postoperative calcitonin level and tumor extension are critical prognostic factors. According to recent research from France, "Imaging-detected relapses are observed in a significant proportion of...

A "catastrophe" may cause rapid progression of pancreatic cancer.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- A "catastrophe" may cause rapid progression of pancreatic cancer. "Exocrine pancreas cancer has a dismal prognosis," scientists writing in the journal Gastroenterology report. "The precise...

Treatment of differentiation arrest in pre-B-cell stage with SLP-65 is curative.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- SLP-65 given at the pre-B-cell stage doesn't allow arrest of differentiation or acute lymphoblastic leukemia type disease in a mouse model. According to a study from Germany, "Acute lymphoblastic...

Breast cancer worry and risk were determinants of prophylactic mastectomy.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Breast cancer worry and risk were determinants of prophylactic mastectomy. "Scientific reports suggest that women at risk for familial breast cancer may benefit from prophylactic mastectomy,"...

Experts in U.K. want entry age for mammographic screening lowered to 47.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Two leading U.K. cancer experts are calling for the entry age for mammographic screening for breast cancer to be reduced from 50 to 47 years for women in Britain. Their rationale is detailed in a...

High fat intake associated with increased risk.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- A large, prospective study of premenopausal women suggests that high intake of animal fat, especially from red meat and dairy products, is associated with an increase in risk of breast cancer. ...

Human breast cancer resistance protein may play a role in sterol transport.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Human breast cancer resistance protein may play a role in sterol transport. "The human breast cancer resistance protein (BCRP, also know as ABCG2, MXR, or ABCP) is one of the more recently...

Ibuprofen, aspirin may reduce woman's risk.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- New research suggests that regular ibuprofen use may cut a woman's risk of developing breast cancer in half. Findings reported July 13, 2003, at the annual meeting of the American Association of...

Study suggests PET not yet ready for disease staging.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Despite its promise as a noninvasive method for diagnosing cancers, positron emission tomography (PET) is not sensitive enough for evaluating lymph node status in patients with breast cancer and should...

Women should not ingest excessive food additives with estrogenic activity.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Women should not ingest excessive food additives with estrogenic activity. According to a study from Japan, "Estrogenic activities of more than 90 chemicals including food additives, foodstuffs of...

Researchers assess cancer mortality risk of workers at the Mayak nuclear complex.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Researchers assess cancer mortality risk of workers at the Mayak nuclear complex. "At present, direct data on risk from protracted or fractionated radiation exposure at low dose rates have been...

Micronucleus assay may correlate with normal tissue damage from radiotherapy.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Micronucleus assay may correlate with normal tissue damage from radiotherapy. "In an effort to find a test to predict the response of normal tissue to radiotherapy, the lymphocyte micronucleus assay...

Acute respiratory failure with diagnosis of monocytic leukemia has poor outcome.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Acute respiratory failure can sometimes be caused by acute monocytic leukemia; outcome worsens after chemotherapy. According to a study from France, "Acute respiratory failure revealing acute...

B-CLL drug resistance may occur due to p53 mutation caused by chemotherapy.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- B-CLL drug resistance may occur following p53 mutation caused by prior DNA damaging chemotherapy. According to a study from Germany, "Inactivation of p53 has been shown to correlate with poor...

Thiotepa absorbed by polyurethane catheter causes falsely elevated plasma levels.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Thiotepa absorbed by polyurethane catheter causes falsely elevated plasma levels. According to a study from Netherlands, "Central venous access catheters are commonly used in clinical oncology. ...

Period analysis gives more up-to-date survival rates than cohort analysis.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Period analysis gives more up-to-date survival rates than cohort analysis. "Survival rates of children with cancer have strongly improved during the past decades, but much of this improvement has...

Standards of expertise in good clinical practice should be established.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Standards of expertise in good clinical practice should be established. "It is a widely held belief that the current system of oversight of clinical research, particularly the means of assessing...

Interim study: Leukine facilitates shortened-schedule chemo regimen.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Interim results from an open-label trial of Leukine (sargramostim) used in combination with an aggressive colon cancer chemotherapeutic regimen indicate administration of the yeast-derived,...

Skills in palliative care are important for appropriate end-of-life care.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Skills in palliative care are important for appropriate end-of-life care. "To increase the knowledge of the final phase of acute myeloid leukemia (AML), a retrospective review of the medical and...

Tumor at the margin after esophagectomy is not a significant prognostic marker.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Tumor at the margin after esophagectomy is not a significant prognostic marker. "The factors affecting long-term survival following esophagectomy for esophageal cancer are poorly understood,"...

Magnetic resonance can image gastric cancer in Tff1 knockout mice.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Magnetic resonance can image gastric cancer in Tff1 knockout mice. "In this work, the use of MRI to stage gastric neoplasia in a mouse model of spontaneous gastric cancer is demonstrated,"...

In vivo electrical conductivity of hepatic tumors is greater than normal tissue.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- In vivo electrical conductivity of hepatic tumors is greater than normal tissue. According to published research from the United States, "Knowledge of electrical tissue conductivity is necessary to...

A patient with intravascular lymphomatosis presents with DIC, brain hemorrhage.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- A patient with intravascular lymphomatosis presents with DIC and brain hemorrhage. According to a study from the People's Republic of China, "Intravascular lymphomatosis (IVL) is a rare angiotrophic...

Chlorambucil given for at least a year does not affect cytogenetic parameters.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Chlorambucil given for at least a year does not affect cytogenetic parameters. According to published research from Israel, "The most common treatment of chronic lymphocytic leukemia (CLL) is the...

Dexrazoxane and anthracyclines lead to a synergistic cytotoxic response in AML.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Dexrazoxane and anthracyclines lead to a synergistic cytotoxic response in AML. According to recent research from the United States, "In an attempt to improve current therapeutic strategies for...

Flavonoid compounds might be useful therapies in acute myelogenous leukemia.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Flavonoid compounds might be useful therapies in acute myelogenous leukemia. According to recent research published in the journal Leukemia Research, "Quercetin and flavopiridol, both flavonoids...

Sequential chemotherapy is effective for newly diagnosed de novo AML.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Sequential chemotherapy is effective for newly diagnosed de novo AML. "EMA, consisting of etoposide, mitoxantrone, and cytarabine, is a timed-sequential chemotherapy (TSC) regimen and an efficacious...

Lifestyle, environmental, and phenotypic factors are associated with lip cancer.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Lifestyle, environmental, and phenotypic factors are associated with lip cancer. According to a study from Spain, "The aim of this study was to identify factors related to lip cancer (LC)...

Renal failure results from non-Hodgkin lymphoma infiltration of the kidneys.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Renal failure can result from non-Hodgkin lymphoma infiltration of the kidneys. According to recent research from Netherlands, "Acute renal failure (ARF) as a consequence of non-Hodgkin lymphoma...

Mucinous adenocarcinoma originates in the urinary bladder.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Mucinous adenocarcinoma can originate in the urinary bladder. According researcher in Italy, "describe a case of mucinous adenocarcinoma with superficial stromal invasion and villous adenoma...

Extended use of paclitaxel delays disease progression in advanced cases.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- A new study shows that women with advanced ovarian cancer who have responded well to first-line chemotherapy can significantly delay progression of the disease if they continue to take paclitaxel after...

Children should be recruited into cancer trials.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Children should be recruited into cancer trials. According to a study from England, "The UK Children's Cancer Study Group (UKCCSG), established in 1977, provides a highly organized structure for...

Complementary therapies for prostate cancer are becoming more popular.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Complementary therapies for prostate cancer are becoming more popular. "Despite its prominence as the most frequently diagnosed solid tumor among men in the United States, relatively little is known...

Perceptions of equipoise are crucial to trial participation.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Perceptions of equipoise are crucial to trial participation. "Recruitment to trials is known to be difficult. Previous research suggests that a crucial factor may be participants' difficulty with...

Bowel inflammation from radiotherapy may produce clostridial myonecrosis.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Bowel inflammation due to radiotherapy is enough to produce remote clostridial myonecrosis and death. According to a study from the United States, "Clostridial myonecrosis (CM) is a rare, life...

BOLD fMRI can assess hemodynamic response to treatment.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- BOLD fMRI can assess hemodynamic response to treatment. "BOLD-contrast functional MRI (fMRI) has been used to assess the evolution of tumor oxygenation and blood flow after treatment. The aim of...

Multidisciplinary approach is required for management and treatment.
August 4, 2003... 2003 AUG 4 - (NewsRx.com & NewsRx.net) -- Multidisciplinary approach is required for management and treatment. "von Hippel-Lindau disease is a heritable multisystem cancer syndrome that is associated with a germline mutation of the VHL...

MR imaging and mammography are good measures of invasive breast malignancy.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- MR imaging and mammography are good at measuring invasive breast malignancies. "To evaluate the accordance of size measurements of malignant breast lesions, 65 women with 76 malignant lesions were...

Researchers give screening guidelines for infants born to women with cancer.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Researchers give screening guidelines for infants born to women with cancer. According to recent research published in the Journal of Pediatric Hematology Oncology, "Cancer in pregnancy is not...

Anemia of cancer can occur before any treatment begins.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Anemia of cancer can occur before any treatment begins. According to recent research published in the journal Bulletin du Cancer, "Thirty percent of cancer patients suffer from anemia before any...

Peripheral opioids act as analgesics in bone cancer pain in mice.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Peripheral opioids act as analgesics in bone cancer pain in mice. "Previous reports have shown that systemic administration of morphine can prevent the thermal hyperalgesia induced by the...

Folic acid supplements may reduce vascular disease and cancer.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Folic acid supplements may reduce vascular disease and cancer. "Folic acid supplements reduce the risk of neural tube defects and may be associated with reduced risk for vascular disease and...

Proliferation rates in melanoma can identify patients with poor outcomes.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Proliferation rates in melanoma can identify patients with poor outcomes. According to a study from Wales, "This prospective study investigated the clinical significance of cell kinetics, measured...

Anemia in cancer patients can be treated with transfusion, erythropoietin.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Anemia can be treated with transfusion and/or erythropoietin. "Most cancer patients experience anemia. It's a main cause of fatigue and it leads to a decrease of the quality of life," scientists...

Glutamine transport in C6 glioma cells shows ASCT2 system characteristics.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Glutamine transport in C6 glioma cells shows ASCT2 system characteristics. According to a study from Poland, "Previous studies from this laboratory have shown that glutamine (Gln) uptake in a rat...

Mammography in women over 40 catches disease earlier.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- For women age 40 and older, annual screening mammography for breast cancer is more effective than infrequent or no mammography in detecting breast cancer at sizes and stages that yield excellent...

American Cancer Society updates guidelines for breast cancer screening.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- American Cancer Society updates guidelines for breast cancer screening. "In 2003, the Amican Cancer Society updated its guidelines for early detection of breast cancer based on recommendations from...

Leukemoid reaction can occur in association with cervical carcinoma.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Leukemoid reaction can occur in association with cervical carcinoma. According to recent research from the United States, "A white blood cell count more than 50 x 10[superscript]9/l associated with...

Primary malignant melanoma of the uterine cervix is rare.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Primary malignant melanoma of the uterine cervix is rare. According to published research from Germany, "The manifestation of a malignant melanoma in the uterus is very rare, more often it is the...

Fine-needle aspiration yields melanin, confirming diagnosis.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Fine-needle aspiration yields melanin, confirming diagnosis. According to recent research from Lebanon, "Diagnosis of clear cell sarcoma by fine-needle aspiration is difficult, as melanin is...

Night-shift work may increase risk of colorectal cancer in women.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Night-shift work may increase risk of colorectal cancer in women. According to published research from the United States, "Exposure to light at night suppresses the physiologic production of...

Little known about risks and benefits of long-term supplement use.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Little is known about risks and benefits of long-term supplement use. "The 1994 passage of Public Law 103-417, the Dietary Supplement and Health Education Act, resulted in an exponential increase...

Rare mesenchymal neoplasm of the esophagus develops in a child.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Rare mesenchymal neoplasm of the esophagus develops in a child. According to a study from Canada, "Mesenchymal neoplasms of the esophagus are relatively uncommon in adults and exceedingly rare in...

Cutaneous granulomas appear as the first manifestation of Hodgkin's disease.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Cutaneous granulomas appear as the first manifestation of Hodgkin's disease. "We report the case of a 64-year-old man in whom fever, cutaneous rash and hepatomegaly were the first manifestations of...

Adenine analogs may be differentiation therapy agents for acute myeloid leukemia.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Adenine analogs may be differentiation therapy agents for acute myeloid leukemia. According to published research from Japan, "Although the frequency of complete remission in acute myeloid leukemia...

Clofarabine-induces acral erythema in two patients.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Clofarabine-induces acral erythema in two patients. "Acral erythema has been associated with a number of chemotherapeutic agents, but there are no reports of clofarabine-induced acral erythema in...

Neurologic complications occur in children receiving L-asparaginase for ALL.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Neurologic complications occur in children receiving L-asparaginase for ALL. According to published research from Germany, "L-asparaginase is frequently used in combination therapy for the...

B cells with aberrant markers along with CD19 indicate increased patient risk.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- In leukemia and lymphoma patients, aberrant markers co-expressed with CD19 on B cells are varied, but are correlated with cancer aggressiveness and lowered survival. "Although some studies have...

Localization in commissure is a risk factor for metastasis in lip cancer.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Localization in commissure is a risk factor for metastasis in lip cancer. "The incidence of lip cancer in Granada, Spain, is much higher than that recorded in other countries," scientists writing...

It is important to attend to physical, emotional needs of lung cancer survivors.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- It is important to attend to physical, emotional needs of lung cancer survivors. According to recent research from the United States, "Little is known about the experience of surviving lung cancer...

Topotecan has established antitumor activity in recurrent SCLC.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Topotecan has established antitumor activity in recurrent SCLC. According to recent research published in the journal Lung Cancer, "Despite the high response rates to chemotherapy, small-cell lung...

Incessant atrial tachycardia resolves after removal of a cerebral tumor.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Incessant atrial tachycardia resolves after removal of a cerebral tumor. According to published research from Spain, "We report the case of an asymptomatic 78-year-old woman in whom incessant atrial...

Newly identified serum biomarkers may be key to earlier diagnosis.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Newly identified serum biomarkers could be the key to earlier diagnosis of ovarian cancer. And earlier diagnosis may result in improved prognosis for women with the disease, often called "the...

Paclitaxel and carboplatin therapy studied in Japanese women.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Paclitaxel and carboplatin therapy has been studied in Japanese ovarian cancer patients. "The aim of this study was clarification of the feasibility, effects, and adverse events of combination...

Role-related meaning scale for pediatric oncology staff is consistent and valid.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Role-related meaning scale for pediatric oncology staff is consistent and valid. "The purpose of this study was to develop and test the Role-Related Meaning Scale for Staff in Pediatric Oncology...

Low signal intensity, poor enhancement on MRI may indicate malignancy.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- MRI findings (low signal intensity, poor enhancement) may indicate malignancy. According to recent research from South Korea, "Salivary duct carcinoma (SDC) is a rare, extremely aggressive...

Androgen receptors are prevalent in three salivary gland malignancies.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Three types of salivary gland tumors are characterized by the presence of androgen receptors (but not estrogen or progesterone receptors); these may be involved in pathogenesis. According to a...

Atypical fibroxanthoma and malignant fibrous histiocytoma may be a single entity.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Atypical fibroxanthoma and malignant fibrous histiocytoma may be a single entity. According to published research from Italy, "A case of cutaneous atypical fibroxanthoma (AFX) which metastasized,...

Patients with neurological symptoms may have paraneoplastic syndrome.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Patients with neurological symptoms may have paraneoplastic syndrome. According to a study from the United States, "We describe a patient who presented with a clinical syndrome of limbic...

Physical activity increases among long-term survivors of testicular cancer.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Physical activity increases among long-term survivors of testicular cancer. "The aim of this study was to estimate the level of physical activity (LPA) in a large cohort of testicular cancer...

Testicular cancer can be cured in most patients.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Testicular cancer can be cured in most patients. According to recent research from France, "Nowadays, testicular cancer can be cured in more than 90% of patients. "Most patients we see note as...

Tc-99m tetrofosmin imaging revealed the lesions better than did the I-131 scan.
August 11, 2003... 2003 AUG 11 - (NewsRx.com & NewsRx.net) -- Tc-99m tetrofosmin imaging revealed the lesions better than did the I-131 scan. According to a study from Turkey, "The authors describe a 42-year-old man with insular thyroid carcinoma. "In...

Psychosocial interventions improve quality of life in adult cancer patients.
August 18, 2003... 2003 AUG 18 - (NewsRx.com & NewsRx.net) -- Psychosocial interventions improve quality of life in adult cancer patients. "The present meta analysis summarized the results of 37 published, controlled studies that investigated the...

NSAID use may be associated with risk of adult leukemia.
August 18, 2003... 2003 AUG 18 - (NewsRx.com & NewsRx.net) -- NSAID use may be associated with risk of adult leukemia. According to recent research from the United States, "Epidemiological studies have suggested that regular use of aspirin and other...

Study affirms safety of oxaliplatin for advanced disease.
August 18, 2003... 2003 AUG 18 - (NewsRx.com & NewsRx.net) -- Results from a large multisite study led by University of Pittsburgh Cancer Institute (UPCI) researcher, Ramesh Ramanathan, MD, demonstrate that the drug oxaliplatin is safe for patients with advanced...

Study examines relation of possible prognostic indicators with clinical signs.
August 18, 2003... 2003 AUG 18 - (NewsRx.com & NewsRx.net) -- An investigation of any potential relationship between traditional clinicopathologic prognostic variables in endometrial carcinoma and the expression of tumor-suppressor gene product p53,...

Older cancer patients may be at higher risk of developing second primaries.
August 18, 2003... 2003 AUG 18 - (NewsRx.com & NewsRx.net) -- Older cancer patients may be at higher risk of developing second primaries. "A case is presented of an elderly patient with synchronous ureteral/bladder/urethral transitional cell carcinoma and...

Protein can predict progression of most common childhood brain tumor.
August 18, 2003... 2003 AUG 18 - (NewsRx.com & NewsRx.net) -- Researchers at UT Southwestern Medical Center at Dallas have discovered that the presence of a particular protein can predict whether the most common childhood brain tumor will continue to grow or...

Olanzapine may be used as antiemetic in refractory nausea/vomiting.
August 18, 2003... 2003 AUG 18 - (NewsRx.com & NewsRx.net) -- Olanzapine may be used as an antiemetic in refractory nausea and vomiting in advanced cancer. "Nausea and vomiting are difficult symptoms to manage in patients with advanced cancer," investigators...

Human erythropoietin improves quality of life in cancer patients.
August 18, 2003... 2003 AUG 18 - (NewsRx.com & NewsRx.net) -- Human erythropoietin improves quality of life in cancer patients. According to a study from Greece, "The purpose of this study was to assess whether the administration of recombinant human...