Clinical Oncology Week articles from April 2009

Clinical Oncology Week archives from April 2009

Small molecules block cancer gene.
April 6, 2009... Finding molecules that block the activity of the oncogene Stat 3 (signal transducer and activator of transcription) required screening literally millions of compounds, using computers that compared the structure of the cancer-causing gene to...

Germany: Colonoscopy prevents 15,000 cancer cases.
April 6, 2009... Since 2002, statutory health insurances in Germany have offered an endoscopic examination of the colon (colonoscopy) free of charge for all insured persons from the age of 55. Germany was the first country to make nationwide endoscopic...

Alcohol 'flush' signals increased cancer risk among East Asians.
April 6, 2009... Many people of East Asian descent possess an enzyme deficiency that causes their skin to redden, or flush, when they drink alcohol. Scientists from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and Japan's Kurihama Alcohol...

NYU study finds new risk factor for melanoma in younger women.
April 6, 2009... Researchers may have found a more potent risk factor for melanoma than blistering sunburns, freckling, or family history of the deadly skin disease. In a new study, scientists at NYU Langone Medical Center report that a genetic variation leads...

Discovery may result in new test to determine predisposition to cancer.
April 6, 2009... Researchers at UCLA's Jonsson Comprehensive Cancer Center have developed an assay that may be used to help identify new genes that can predict a predisposition to cancer (see also University of California - Los Angeles). The study,...

A new theoretical model of tumor growth and metastasis based on differences in tissue pressure.
April 6, 2009... The HFSP Journal, the interdisciplinary journal for scientists conducting high quality, innovative research at the interface between biology and the physical sciences is pleased to announce that the latest article modelling of tumor growth and...

Multifocal lung cancers appear to originate from single cancer clone.
April 20, 2009... Multiple, anatomically distinct lung cancer tumors may frequently arise from a single cancer cell, according to a retrospective analysis of patient tumor samples published in the April 7 online issue of the Journal of the National Cancer...

New human papillomavirus research from University of New Mexico discussed.
April 20, 2009... "We evaluated the impact of a quadrivalent human papillomavirus (HPV) vaccine on infection and cervical disease related to 10 nonvaccine HPV types (31, 33, 35, 39, 45, 51, 52, 56, 58, and 59) associated with >20% of cervical cancers. The...

Studies from University of Guelph in the area of life sciences published.
April 20, 2009... "The solution conformational behavior of the Tumor-Associated Carbohydrate Antigen Le(a)Le(x) central fragment: methyl alpha-L-fucopyranosyl-(1 → 4)-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1 → 3)-beta-D-galactopyranoside was...

Nature Publishes Preclinical Data on an Inhibitor of a Novel Target Discovered by Millennium.
April 20, 2009... Takeda Pharmaceutical Company and Millennium: The Takeda Oncology Company announced publication of an article describing the discovery of MLN4924--a small molecule inhibitor of the NEDD8-Activating Enzyme (NAE) in the journal Nature (see also...

A 'bionic nose' that knows.
April 27, 2009... Both cancer cells and the chemicals used to make bombs can foil detection because they appear in trace amounts too small for conventional detection techniques. Tel Aviv University has developed the ultimate solution: a molecule that can magnify...

New method for detection of phosphoproteins reveals regulator of melanoma invasion.
April 27, 2009... Scientists have developed a new approach for surveying phosphorylation, a process that is regulated by critical cell signaling pathways and regulates several key cellular signaling events. The research, published by Cell Press in the April 10th...

Reports from Baylor College of Medicine, College of Medicine highlight recent research in immunization.(Report)
April 27, 2009... According to a study from the United States, "Virus-like particles (VLPs) have gained increasing interest for their use as vaccines due to their repetitive antigenic that is capable of efficiently activating the immune system. The efficacy of...

Data on melanoma reported by Y. Akiyama and co-researchers.
April 27, 2009... According to a study from Shizuoka, Japan, "A MAGE-1 HLA-A24 peptide-specific CTL line was characterized using a novel staining approach in the case of a metastatic melanoma patient who exhibited a remarkable clinical response in HLA-A24...

EAU Position Statement on Screening for Prostate Cancer.
April 27, 2009... The European Association of Urology (EAU) has taken into consideration the recent scientific information on randomised screening studies on prostate cancer (Schr=F6der et al, NEJM 2009). Based on the results of the European Randomised Study for...