Cardiovascular Week articles from November 2003

Cardiovascular Week archives from November 2003

Hispanic heart patients have best survival rates.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- A study looking at more than 47,000 cardiac patients at two Veterans Affairs (VA) medical centers over 12 years found that Hispanics had the best survival rate, compared to whites and African Americans....

A new technique heightens the efficacy of transcoronary gene delivery.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- A new technique heightens the efficacy of transcoronary gene delivery. "High-efficiency somatic gene transfer in adult mouse heart has not yet been achieved in vivo. Here, we demonstrate...

Aorta area ratio can be used in noninvasive quantitation of flow turbulence.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Postvalvular aorta to valvular orifice cross-sectional areas ratio can be used in noninvasive quantitation of blood flow turbulence in aortic valve disease. According to a study from France,...

Cardiac imaging can be "gatekeeper" for implantable heart-shocker.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- High-tech images of the heart and its surrounding blood flow can help identify patients who will benefit most from implanted electronic devices that treat heart rhythm disturbances, according to a new...

CPR improves quality of life for cardiac arrest survivors.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Cardiac arrest survivors who received bystander CPR were likely to have a "good quality of life" 1 year later, according to a new report. The findings refute the notion that cardiac arrest survivors...

Elevated soluble E-selectin indicates increased heart disease risk.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Obese patients with the angiotensin-converting enzyme gene polymorphism and elevated levels of soluble E-selectin have an increased risk for cardiovascular disease. "Fifty-six young central obese...

Cell infusions boost heart function, revive damaged heart muscle.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Infusing a patient's own cells into a heart artery several days after a heart attack speeds the healing process and strengthens the heart's pumping power, researchers report. In a small study of...

Update provided on FDA review of PMR System.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- CardioGenesis Corporation (CGCP), a provider of angina-relieving Transmyocardial Revascularization (TMR) and percutaneous myocardial revascularization (PMR), announced that the company and the U.S. Food...

Two-stage procedures create rodent models of severe limb ischemia at rest.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Two-stage procedures create rodent models of severe limb ischemia at rest. "We sought an animal model able to discriminate metabolic and angiogenic processes in limb ischemia. For that we modified...

On-X prosthetic heart valve maker begins aspirin study.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Medical Carbon Research Institute, L.L.C., (MCRI), manufacturer of the On-X prosthetic heart valve, announced the initiation of a clinical study under an aspirin-only anticoagulation protocol. The...

Death risk hinges on choice of surgeon, study finds.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- If the largest blood vessel in your body threatens to burst, a new study finds that your best bet is to have it repaired by a surgeon who has operated on many other patients with the same condition. If...

Catheter insertion site can make a difference for apheresis patients.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- The site of insertion and other aspects concerning catheters can make a difference for apheresis patients. According to published research from Germany, "In the intensive care unit, apheresis...

Cellular fat sensor slows heart disease.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- A cellular sensor of dietary fats slows the development of lesions that lead to heart disease, a Salk Institute study has found. The study, which appears in Science, uncovers a unique pathway that...

Excess vascular endothelial growth factor associates with hyperhomocysteinemia.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Excess vascular endothelial growth factor associates with hyperhomocysteinemia. "Hyperhomocysteinemia has been reported to be an independent risk factor for atherosclerosis and atherothrombosis....

Soft-patch device used to close hole in heart of pediatric patient.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Without performing surgery, a physician at Advocate Hope Children's Hospital in Oak Lawn, Illinois, has used a special instrument successfully to patch a hole in the heart wall of an infant. The child...

Inflammatory marker levels associated with body mass index.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Inflammatory marker levels are associated with body mass index. "Obesity is a risk factor for venous and arterial thrombosis. We examined relationships between body mass index (BMI) and a number of...

Adeno-associated virus looks promising for different cardiac gene therapies.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Adeno-associated virus looks promising for different cardiac gene therapies. "Intracardiac gene transfer and gene therapy have been investigated with different vector systems. Here we used...

EnSite NavX released for visualization of heart chambers.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Endocardial Solutions, Inc., (ECSI) announced the release of the next version of its EnSite NavX intracardiac non-fluoroscopic navigation system. EnSite NavX, which was first released in May of this...

MDdatacor hits milestone, with 2 million cardiology patients in database.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- MDdatacor, inc., announced at Barnett International's eighth annual Strategies to Maximize Patient Recruitment Conference that it has accumulated longitudinal medical data for more than 2 million...

Maximo implantable cardioverter defibrillator gets FDA approval.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Medtronic, Inc., (MDT) announced approval by the U.S. Food and Drug Administration of the Maximo implantable cardioverter-defibrillator (ICD). The Maximo ICD is built on the platform of the...

Reactive oxygen species are necessary mediators of coronary collateralization.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Reactive oxygen species are necessary mediators of coronary collateralization. "Recent evidence suggests that reactive oxygen species (ROS) promote proliferation and migration of vascular smooth...

The short peptide KRX-725 demonstrates therapeutic potential.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- The short peptide KRX-725 demonstrates therapeutic potential. According to a study from Israel, "the G-protein-coupled receptors of the endothelial differentiation gene (EDG) family mediate...

NIH grant to be used for development of stem cell treatment.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Aastrom Biosciences, Inc., (ASTM) announced that it has received a $100,000 Phase I Small Business Innovation Research grant from the U.S. National Institutes of Health (NIH) to develop a bone marrow...

Fibrin polymerization rate in antiphospholipid syndrome plus SLE may be a risk.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Patients with antiphospholipid syndrome plus lupus have an increased fibrin polymerization rate that may be a clotting risk. "The main event in blood coagulation is the thrombin-catalyzed...

HMO enhances diabetes and heart disease programs.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Oxford Health Plans, Inc., (OHP) announced a new 5-year agreement with American Healthways (AMHC), the nation's largest provider of disease management and care enhancement services. In addition to...

New drug to be marketed in U.S. to treat congestive heart failure.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Pfizer, Inc., has received approval from the U.S. Food and Drug Administration (FDA) to market Inspra (eplerenone tablets) for the treatment of congestive heart failure (CHF) in patients who have had a...

Level of an advanced glycated end product is genetically determined.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- A study involving normal twins revealed that the level of an advanced glycated end product is genetically determined. According to recent research from England and Germany, "Reducing sugars react...

Three-year pact signed for congestive heart failure patient management.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- American Healthways, Inc., (AMHC) announced the signing of a 3-year agreement with Horizon Healthcare Services, Inc., and its subsidiary, Horizon Healthcare of New Jersey, Inc., (Horizon) to provide the...

EBV mononucleosis with thrombocytopenia can have anti-platelet autoantibodies.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- EBV mononucleosis can cause immune thrombocytopenia, with autoantibodies to platelet glycoproteins present. "In this study, we detected autoantibodies to platelet glycoproteins GPIIb/IIIa and...

Submaximal exercise in humans shifts the angiogenic balance in muscle tissue.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Submaximal exercise in humans shifts the angiogenic balance in muscle tissue. "Angiogenesis, the growth of new blood vessels from existing ones, occurs in the skeletal muscle as an adaptive response...

Prenatal ultrasound yields a diagnosis of portal vein thrombosis.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Prenatal ultrasound yields a diagnosis of portal vein thrombosis. According to published research from the United States, "neonatal portal vein thrombosis (PVT) is a rare condition seen in the...

New insights into how estrogen works may lead to improved stroke treatments.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- A team of researchers working in Texas and Florida have discovered new insights into how estrogen works, a finding that may lead to better treatments for stroke patients. The researchers are from...

Agents targeting angiogenesis in older patients should be disease-specific.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Agents targeting angiogenesis in older patients should be disease-specific. "Angiogenesis is impaired in aged tissues. It is probable that this deficit contributes to the increased severity of...

Adrenomedullin gene delivery lowers I/R-induced heart attack risk.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Adrenomedullin (AM) gene delivery reduces the risk of heart attacks in ischemic mice. AM "has been shown to protect against cardiac remodeling," scientists in the United States noted. In a...

Feasibility phase of trials for CABG expanded.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- CardioTech International, Inc., (CTE) announced that it is expanding the number of hospitals and clinical investigators participating in the feasibility phase of its clinical trial for its patented...

Soy protein does lower cholesterol and can reduce risk of heart disease.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- A daily diet including soy protein really can lower cholesterol and possibly reduce the risk of heart disease, according to an article in the October issue of the Mount Sinai School of Medicine...

Haptoglobin-hemoglobin complex-specific Fab antibody blocks binding to CD163.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- A haptoglobin-hemoglobin complex-specific Fab antibody was capable of blocking the binding of the complex to CD163. "During intravascular hemolysis, hemoglobin (Hb) binds to haptoglobin (Hp)...

Recognition software gets European CE Mark.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Medicsight, Inc., (MSHT) has developed what it says is the first viable medical-image-analysis technology to enable accurate, reproducible, and cost-effective radiological interpretation of scans of...

S. pneumoniae DNA persists on heart valve years after infection.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- A case study suggests that streptococcal DNA may remain in the heart for years after infection. In a recent study, scientists in France "amplified by PCR and sequenced Streptococcus pneumoniae rpoB...

Drug development discontinued due to unsatisfactory preliminary data.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Xoma Ltd. has discontinued development of MLN2201, a humanized monoclonal antibody being developed for conditions related to inflammation of the heart and blood vessels. MLN2201 was one of two...

Liprostin human clinical trials to commence.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Endovasc, Inc., (EVSC), an early-stage drug development company that pioneers new cardiovascular and metabolic drug therapies, announced that it has received approval from the Republic of Georgia's...

Human blast lung injury due to explosives creates lung emboli even in fat.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Human lung injury due to explosive detonation creates lung emboli even in fat, and must be considered a risk in survivors, too. "The objective of this autopsy-based study was to investigate the...

Device firm introduces new mitral valve repair ring.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Edwards Lifesciences Corporation (EW) announced the initial implants of its Carpentier-McCarthy-Adams IMR ETlogix Annuloplasty ring, designed for the unique requirements of ischemic mitral heart valve...

Heart problems in women linked to job insecurity.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Researchers at Brigham and Women's Hospital (BWH), Massachusetts, have found that a woman's heart attack risk may be influenced by concerns over potential loss of employment. After following almost...

Alpha-lipoic acid inhibits adipocyte differentiation.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Alpha-lipoic acid inhibits adipocyte differentiation by regulating pro-adipogenic transcription factors via mitogen-activated protein kinase pathways. According to recent research from South Korea...

Patents issued for inhibitors of imidazoline receptors.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Immtech International, Inc., (IMM) announced that the U.S. and Australian patent offices have awarded Immtech's scientific consortium, comprising the University of North Carolina at Chapel Hill (UNC)...

Improving physical fitness, insulin sensitivity may help Latino children at risk.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Reducing insulin resistance and boosting the fitness of overweight Latino children at high risk for type 2 diabetes will be crucial in efforts to protect them from diabetes and heart disease, according...

Dr. Soon John Park joins Sutter collaborative heart program.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Soon John Park, MD, a cardiovascular and thoracic surgeon and researcher, is joining a Sutter Health collaborative heart program between California Pacific Medical Center in San Francisco, California,...

Pharmaceutical corporation acquires Dibenzyline injectable.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- WellSpring Pharmaceutical Corporation has licensed the United States rights to the trademark, scientific data, technology, and know how for Dibenzyline (phenoxybenzamine hydrochloride) injection from...

Company recalls 3.0 mm-diameter Multi-Link Vision coronary-stent system.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Guidant Corp. (GDT) has initiated a voluntary recall of certain manufacturing lots of the 3.0 mm-diameter Multi-Link Vision coronary-stent system. The action will affect customers in the United...

NCQA selects McKesson to review HEDIS codes for accuracy.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- McKesson Corp. announced it has been awarded a 1-year contract by the National Committee for Quality Assurance (NCQA) to ensure the accuracy and completeness of clinical coding for all Health Plan...

FDA approves the Driver coronary stent.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Medtronic, Inc., (MDT) announced that the company has received U.S. Food and Drug Administration (FDA) approval for the Driver coronary stent. The Driver stent is Medtronic's premium cobalt-based...

Cortical subdivisions adjacent to focal stroke are cellular signaling sites.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Tissue microenvironments within functional cortical subdivisions adjacent to focal stroke are sites of distinct reactive cellular signaling. According to recent research published in the Journal of...

Nursing home residents, minorities undertreated for recurrent stroke.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Only half of elderly Americans in nursing homes are treated to prevent recurrent strokes, according to a review of nursing home admission records. The study also showed racial minorities receive...

Cause in younger women is unknown.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- The number of women in their 30s and 40s who experience sudden cardiac death is increasing much faster than the number of men of the same age who experience sudden cardiac death - and researchers don't...

Canadian approval granted for new premix CoSeal.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Angiotech Pharmaceuticals, Inc., (ANPI; ANP) announced that it has received approval from Health Canada to market a new premixed configuration of CoSeal, the same formulation that was approved by the...

Epinephrine safe for hemostasis during burn surgery.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Epinephrine is safe for use to reduce blood loss during surgical burn treatment. "Although subcutaneous and topical epinephrine are widely used for hemostasis during burn surgery, the acute systemic...

Modified human hemoglobin enables targeted oxygen delivery.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- A modified form of human hemoglobin shows promise for targeted oxygen delivery. "To assess O[subscript]2 delivery to tissue by a new surface-modified, polyethylene glycol-conjugated human hemoglobin...

Effects of ETA signaling on neural crest development clarified.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- The effects of ETA signaling on neural crest development have been elucidated. "Craniofacial and cardiac development relies on the proper patterning of the neural crest-derived ectomesenchyme of...

High-dose pergolide may increase cardiovascular disease risk.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- High-dose pergolide treatment may increase the risk of cardiovascular disease in Parkinson disease patients. Scientists in Belgium reported "the clinical, echocardiographic, and pathologic...

Cardiac scoring systems may not be satisfactory in predicting outcome.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- Cardiac scoring systems may not be satisfactory in predicting outcome. "Estimating the perioperative risk of major adverse cardiac events is one of the functions of cardiac risk scoring systems, '...

Viral vectors deliver genes to the coronary microvessels of canine models.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- Viral vectors deliver genes to the coronary microvessels of canine models. "The objective of this study was to assess the potential of adeno-associated virus (AAV)-mediated gene delivery into...

Cardiovascular autonomic function correlates with aerobic training response.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- Cardiovascular autonomic function correlated with the response to aerobic training in healthy sedentary subjects. According to published research from Finland, "Individual responses to aerobic...

Direct thrombin inhibitors are safe and effective for venous thromboembolism.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- Direct thrombin inhibitors are safe and effective for venous thromboembolism. "Venous thromboembolism (VTE) is a common and potentially lethal disease that recurs frequently and is associated with...

Iron-based anemia treatments inhibit transendothelial PMN migration.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- Iron-based anemia treatments can suppress transendothelial PMN migration. "Although iron sucrose and iron gluconate are generally well tolerated in patients who are treated for renal anemia, recent...

Current outcomes in endovascular repair of abdominal aortic aneurysms discussed.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- Current outcomes in endovascular repair of abdominal aortic aneurysms are discussed. According to published research from the United States, "The repair of abdominal aortic aneurysms has presently...

Improved CAA classification system developed.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- An improved CAA classification system has been developed. "Many fragmental classification of coronary artery anomalies (CAAs) exist, but a simple practical angiographic classification for...

Oral L-arginine improves endothelial function in healthy elderly individuals.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- Oral L-arginine treatment improves endothelial function in healthy elderly individuals. "Aging is associated with progressive endothelial dysfunction in normal humans," scientists in Germany...

VCI does not predict CVP in ventilated premature infants.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- VCI does not predict CVP in premature infants who require mechanical ventilation. According to published research from the Netherlands, "To determine the value of noninvasive assessment of right...

Vascular surgeons develop new technique to repair arch defect.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- A novel treatment developed by University of California San Francisco (UCSF) vascular surgeons has been used in a first-of-its-kind operation to repair a life-threatening aneurysm in the patient's...

Ablation system for atrial fibrillation released to Europe's heart surgeons.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- Medtronic, Inc., (MDT) announced commercial availability in Europe of the Cardioblate Bipolar (BP) Surgical Ablation System, which is designed to help surgeons treat one of the world's most difficult...

Freezor MAX, Freezor Xtra successful in ablating atrial flutter.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- CryoCath Technologies, Inc., (CYT) announced that two abstracts pertaining to the ablation of atrial flutter using the company's Freezor MAX and Freezor Xtra catheters were presented in Venice, Italy,...

Myogen announces drug discovery collaboration.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- Myogen, Inc., a biopharmaceutical company focused on the discovery, development, and commercialization of small-molecule therapeutics for the treatment of cardiovascular disease, announced a research...

Factor XIII improves performance of fibrin sealants.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- The efficacy of fibrin sealants can be improved with the addition of factor XIII. This enzyme "has a well-established role in natural coagulation and clot stabilization," scientists in the United...

Maternal diabetes stalls proper vascular development in embryos.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- Maternal diabetes stalls proper vascular development in embryos. According to a study from the United States, "major congenital malformations, many of which result from abnormal cardiovascular...

FDA issues 510-k approval for hand-held pulse oximeter.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- OSI Systems, Inc., (OSIS) announced that its majority owned subsidiary, Dolphin Medical, Inc., has received 510(k) approval from the U.S. Food and Drug Administration (FDA) to market its Dolphin ONE...

Use of statins may prevent disease in older women.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- Cholesterol-lowering medications may help to prevent breast cancer in older women, study results suggest. "While scientists have known for years that cholesterol inhibition serves to inhibit tumor...

Study demonstrates BioZ ICG changes emergency treatment 24% of time.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- CardioDynamics (CDIC), developer of Impedance Cardiography (ICG) technology and manufacturer of BioZ noninvasive cardiac function monitoring systems, announced significant results of the ED-IMPACT...

Carboxyl terminus of beta(2)AR needed for cardiac myocyte signaling.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- The carboxyl terminus of beta(2)AR is essential for cardiac myocyte signaling. According to recent research from California, "beta(1)- and beta(2)-adrenergic receptors (AR) regulate cardiac myocyte...

Apoptosis proteins bax and bcl-2, not p53, are increased in cardiomyopathy.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- Apoptosis related proteins bax and bcl-2, but not p53, are overexpressed in cardiomyopathy patients; bcl-2 is associated with failing myocardium. According to a study from Taiwan, "The relation...

Alphoid-HindIII Y-mutation increases risk of early heart attack in hypertensives.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- The alphoid-HindIII mutation in the Y chromosome increases the heart attack risk in young hypertensive men. "A single nucleotide polymorphism (SNP) in chromosome Y has been associated with blood...

Apolipoprotein B gene mutations have limited effect on heart disease risk.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- Mutations in the APOB gene have significant effects on lipid levels, but a limited impact on heart disease risk. "Apolipoprotein B (apoB) is the sole protein component of low-density lipoprotein...

Biventricular pacing linked to long-term improvement in asynchrony patients.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- Biventricular pacing (BiV) is associated with long-term improvement of cardiac asynchrony. According to published research from France, BiV therapy "is emerging for patients with dilated...

Further diet changes needed to reduce CVD risk in the U.K.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- Further dietary changes are needed to lower the rate of cardiovascular disease (CVD) in the United Kingdom. According to recent research from Ireland, CVD "is a leading cause of premature death in...