Cancer Vaccine Week articles from September 2008

Cancer Vaccine Week archives from September 2008

Investigators at Johns Hopkins University release new data on cancer vaccines.
September 1, 2008... " To examine the efficacy of adjuvant chemoradiotherapy after pancreaticoduodenectomy (PD) for pancreatic adenocarcinoma (PC) in patients undergoing resection at Johns Hopkins Hospital (JHH; Baltimore, MD). Patients and Methods Between August...

New cancer vaccines findings from Jilin University described.
September 1, 2008... "Infection with high-risk human papillomavirus is an important factor associated with cervical cancer, and the distribution of HPV types varies greatly worldwide. Determination of typespecific HPV prevalence constitutes an important step...

New cancer vaccines research reported from Emory University.
September 1, 2008... "Follicular lymphoma (FL) is a common indolent lymphoma associated with a relapsing course. Preclinical models and clinical studies demonstrate that immunizing FL patients against their own tumor idiotype induces humoral and cellular immunity...

New findings from National Institutes of Health in the area of cancer vaccines described.
September 1, 2008... "Nonmutated tissue differentiation antigens expressed by tumors are attractive targets for cancer immunotherapy, but the consequences of a highly effective antitumor immune response on self-tissue have not been fully characterized. We found...

Studies from Johns Hopkins University, Medical Department have provided new data on cancer vaccines.
September 1, 2008... "There is an urgent need to develop new innovative therapies for the control of cancer. Antigen-specific immunotherapy and the employment of proteasome inhibitors have emerged as two potentially plausible approaches for the control of cancer,"...

Research on cancer vaccines detailed by scientists at University of Pittsburgh, Department of Immunology.
September 1, 2008... Data detailed in 'Cancer vaccines: accomplishments and challenges' have been presented. "Advancements in knowledge in diverse fields of science, including genetics, cell biology, molecular biology and biochemistry, have shed light on the...

Scientists at Medical University of Lublin publish research in immunotherapy.(Clinical report)
September 1, 2008... Scientists discuss in 'Immunotherapy with irradiated autologous leukemic cells in patients with B-CLL in early stages' new findings in immunotherapy. "In this study 10(7) peripheral blood mononuclear cells including on average 78.56% CD19+/CD5+...

Data on reovirus therapy described by researchers at Institute of Hematology and Blood Transfusion.
September 1, 2008... Investigators publish new data in the report 'Efficacy of reovirus therapy combined with cyclophosphamide and gene-modified cell vaccines on tumors induced in mice by HPV16-transformed cells.' "Oncolytic virotherapy is a novel approach to...

Crystal Research Associates, LLC Issues Executive Informational Overview(R) (EIO(R)) on Generex Biotechnology Corporation.
September 1, 2008... Crystal Research Associates, LLC announced that it has issued an Executive Informational Overview(R) (EIO(R)) on Generex Biotechnology Corporation (NASDAQ:GNBT). The full 64-page report can be found at www.crystalra.com (see also Cancer...

NovaRx Initiates Pivotal Phase III Clinical Trial in Lung Cancer Patients.(Clinical report)
September 1, 2008... NovaRx Corporation announced that the company initiated its pivotal Phase III clinical trial of Lucanix(R) (belagenpumatucel-L) in the treatment of advanced non-small cell lung cancer (NSCLC). The first patient enrolled in the study was treated...

Cervical cancer prevention should focus on vaccinating adolescent girls.
September 1, 2008... The cost-effectiveness of vaccination in the United States against human papillomavirus (HPV), a sexually-transmitted virus that causes cervical cancer, will be optimized by achieving universal vaccine coverage in young adolescent girls, by...

WXYZ-TV/Channel 7 is 'On Your Side' With Healthy Living for Kids; Free Immunizations for Children on Sunday, August 24 at Charles H. Wright Museum of African American History.
September 1, 2008... WXYZ- TV/Channel 7 and The Detroit Department of Health and Wellness Promotion will give thousands of Detroit metro area children a "boost" at the 31st annual "HEALTHY LIVING FOR KIDS" program. This year the program will be held Sunday, August...

Findings from University of Naples broaden understanding of cancer vaccines.
September 8, 2008... "Heat shock protein B (HspB) is one of the dominant proteins recognized by most Helicobacter pylori-infected persons and is being considered as potential candidates for subunit vaccines. In the present study we describe the generation of an...

Findings in cancer vaccines reported from C.J. Wheeler and co-researchers.(Clinical report)
September 8, 2008... "Cancer vaccine trials have failed to yield robust immune-correlated clinical improvements as observed in animal models, fueling controversy over, the utility of human cancer vaccines. Therapeutic vaccination represents an intriguing additional...

Recent findings from University of Texas highlight research in cancer vaccines.
September 8, 2008... According to recent research from the United States, "Heat shock proteins (HSPs) are highly conserved stress-induced proteins which function as chaperones for trafficking peptides inside different cellular compartments and delivering peptides....

Reports outline cancer vaccines study results from University of Pittsburgh.
September 8, 2008... According to recent research from the United States, "Preferential activation of regulatory T (Treg) cells limits autoinumme tissue damage during chronic immune responses but can also facilitate tumor growth. Here, we show that tissue-produced...

Research results from Sahlgrenska University update knowledge of cancer vaccines.
September 8, 2008... According to recent research from Gothenburg, Sweden, "Recruitment of circulating natural killer (NK) cells into inflamed lymph nodes is known to provide a potent, IFN-gamma-dependent boost for Th1-polarized immune responses in mouse models....

Data on cancer vaccines described by researchers at University of Southampton, Cancer Sciences Division.
September 8, 2008... Investigators publish new data in the report 'DNA fusion gene vaccination mobilizes effective anti-leukemic cytotoxic T lymphocytes from a tolerized repertoire.' "The majority of known human tumor-associated antigens derive from non-mutated...

Researchers from National Institutes of Health describe findings in cancer vaccines.
September 8, 2008... Current study results from the report, 'Safety and immunologic response of a viral vaccine to prostate-specific antigen in combination with radiation therapy when metronomic-dose interleukin 2 is used as an adjuvant,' have been published. "We...

Researchers from Providence Portland Medical Center publish findings in cancer vaccines.
September 8, 2008... Scientists discuss in 'Phenotype and functional characterization of long-term gp100-specific memory CD8+ T cells in disease-free melanoma patients before and after boosting immunization' new findings in cancer. According to recent research...

Researchers from University of Palermo detail findings in cancer vaccines.(Report)
September 8, 2008... A new study, 'Prevalence of genital human papilloma virus infection and genotypes among young women in Sicily, South Italy,' is now available. According to a study from Palermo, Italy, "Infection with oncogenic human papilloma virus (HPV) types...

Catholic University of Korea publishes research in gene therapy.(Report)
September 8, 2008... Research findings, 'Efficient antitumor immunity in a murine colorectal cancer model induced by CEA RNA-electroporated B cells,' are discussed in a new report. According to a study from Seoul, Korea, "RNA electroporation as a gene delivery...

Investigators at University of Michigan, Comprehensive Cancer Center release new data on immunization.
September 8, 2008... Investigators publish new data in the report 'The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity.' According to recent research from the United States, "Aluminum...

New immunology research reported from Southampton University, Cancer Sciences Division.(Report)
September 8, 2008... New research, 'CD11c provides an effective immunotarget for the generation of both CD4 and CD8 T cell responses,' is the subject of a report. According to recent research from Southampton, the United Kingdom, "The magnitude and quality of T...

Researchers from Massachusetts Institute of Technology report on findings in vaccines.(Report)
September 8, 2008... Researchers detail in 'Injectable dendritic cell-carrying alginate gels for immunization and immunotherapy,' new data in vaccines. "Dendritic cell vaccines, in which antigen-loaded dendritic cells (DCs) are injected directly into patients to...

Finalists nominated for the 2008 EUROPEAN BIOTECHNICA AWARD.
September 8, 2008... The three finalists of the 2008 EUROPEAN BIOTECHNICA AWARD have been determined. The biotechnology companies nominated are Cambridge-based Astex Therapeutics Limited (UK), GENEART AG from Regensburg (Germany) and immatics biotechnologies GmbH...

CDC Urges Pre-Teen Vaccination With New Public Service Announcements.
September 8, 2008... The Centers for Disease Control and Prevention's (CDC) National Center for Immunization and Respiratory Diseases announced that new public service announcements (PSAs) targeting the parents of pre-teens are now available to broadcast...

Investigators at Children's Hospital zero in on cancer vaccines.(Report)
September 15, 2008... "Objective and Participants: In 2006, the authors examined intention to receive an HPV vaccine among 340 college students. A total of 138 men and 202 women completed questionnaires," investigators in the United States report (see also Cancer...

Investigators at Research Center zero in on cancer vaccines.
September 15, 2008... "Compelling evidences indicate a key role for regulatory T cells (T-reg) on the host response to cancer. The Wilms' tumor antigen (WT1) is overexpressed in several human leukemias and thus considered as promising target for development of...

Research in the area of human papillomavirus reported from J.L. Pretet and colleagues.
September 15, 2008... According to recent research from Besancon, France, "In the present study (EDiTH III study), the genotype-specific prevalence of HPV in low-grade squamous intraepithelial lesions (LSIL) was estimated to predict the potential benefit of HPV...

Research from Duke University in life sciences provides new insights.
September 15, 2008... "CD4+CD25'''9''FoxP3+ regulatory T (Treg) cells limit antigen-specific immune responses and are a cause of suppressed anticancer immunity. In preclinical and clinical studies, we assessed the immune consequences of FoxP3+ Treg-cell depletion in...

Data on cancer vaccines described by researchers at Harvard University.
September 15, 2008... Investigators publish new data in the report 'Exploring the cost-effectiveness of HPV vaccination in Vietnam: insights for evidence-based cervical cancer prevention policy.' "Using mathematical models of cervical cancer for the northern and...

Researchers from Harvard University describe findings in cancer vaccines.
September 15, 2008... Current study results from the report, 'Health and economic outcomes of HPV 16,18 vaccination in 72 GAVI-eligible countries,' have been published. "The risk of dying from cervical cancer is disproportionately borne by women in developing...

Investigators at National Institute of Epidemiology release new data on hepatitis B virus epidemiology.
September 15, 2008... Data detailed in 'Epidemiology of hepatitis B virus infection among the tribes of Andaman and Nicobar Islands, India' have been presented. According to a study from Chennai, India, "The Andaman and Nicobar Islands, Union Territory of India, are...

Findings from Monash University, Cancer Council broaden understanding of immunization.(Clinical report)
September 15, 2008... Current study results from the report, 'Comparison of self-reported and recorded vaccinations and health effects in Australian Gulf War veterans,' have been published. "Vaccinations, and multiple vaccinations in particular, have been associated...

News from CA: Cancer Quality Alliance, blueprint for a better cancer care system.
September 15, 2008... Blueprint for a Better Cancer Care System In this report, the Cancer Quality Alliance (CQA), a national alliance advocating for improvements in the quality of cancer care in America, presents a set of 5 case studies that depict a vision of...

Scientists Who Linked HPV with Cervical Cancer Win 20th Annual Warren Alpert Foundation Prize.
September 15, 2008... Two scientists who discovered that specific types of human papillomavirus, or HPV, cause cancer of the cervix were announced as winners of the 20th annual Warren Alpert Foundation Scientific Prize (see also Warren Alpert Foundation). The...

Research on cancer vaccines discussed by R.J. Amato and co-researchers.
September 22, 2008... "The attenuated vaccinia virus, modified vaccinia Ankara, has been engineered to deliver the tumor antigen 5T4 (TroVax). TroVax has been evaluated in an open-label phase 2 trial in hormone refractory prostate cancer patients in which the...

Researchers at University of London publish new data on cancer vaccines.(Report)
September 22, 2008... "This study examined cancer research stories on the BBC web archive (July 1998 - June 2006). There were about 260 BBC stories per year, of which about 170 were classed as relevant to reports of cancer research," investigators in London, the...

Researchers from University of Tartu report recent findings in helicobacter.
September 22, 2008... According to a study from Ravila, Estonia, "Helicobacter pylori infection causes chronic gastritis, peptic ulcer, and gastric cancer. Colonization of H. pylori in the stomach activates Toll-like and Nod-like receptors to induce not only innate...

New findings reported from G.R. Rossi and co-authors describe advances in immunotherapy.(Report)
September 22, 2008... According to a study from the United States, "Owing to the absence of alpha Gal epitopes in human cells and constant stimulation of the immune system by the symbiotic bacterial flora, humans develop high titers of natural antibodies against...

Data on cancer vaccines described by researchers at Chittaranjan National Cancer Institute.
September 22, 2008... Investigators publish new data in the report 'Neem leaf glycoprotein helps to generate carcinoembryonic antigen specific anti-tumor immune responses utilizing macrophage-mediated antigen presentation.' "In an objective to generate effective...

Data on cancer vaccines discussed by researchers at Children's Hospital, Department of Hematology-Oncology.
September 22, 2008... A report, 'CpG oligodeoxynucleotides alter lymphocyte and dendritic cell trafficking in humans,' is newly published data in Clinical Cancer Research. According to a study from the United States, "CpG oligodeoxynucleotides (CpG-ODN) are being...

Scientists at Okayama University discuss research in cancer vaccines.(Report)
September 22, 2008... New investigation results, 'Induction of immune response against NY-ESO-1 by CHP-NY-ESO-1 vaccination and immune regulation in a melanoma patient,' are detailed in a study published in Cancer Immunology, Immunotherapy. According to a study from...

Scientists at University of Maryland, Department of Biological Sciences report research in cancer vaccines.
September 22, 2008... A new study, 'Lung cancer patients' CD4(+) T cells are activated in vitro by MHC II cell-based vaccines despite the presence of myeloid-derived suppressor cells,' is now available. "Advanced non-small cell lung cancer (NSCLC) remains an...

Scientists at University of Texas, M. D. Anderson Cancer Center publish research in cancer vaccines.
September 22, 2008... Scientists discuss in 'The E75 HER2/neu peptide vaccine' new findings in cancer. "E75 (HER2/neu 369-377) is an immunogenic peptide from the HER2/neu protein which is overexpressed in many breast cancer patients. A large amount of preclinical...

Scientists at Medical University of South Carolina detail research in cancer vaccines immunology.
September 22, 2008... Researchers detail in 'Gamma-IFN-inducible-lysosomal thiol reductase modulates acidic proteases and HLA class II antigen processing in melanoma,' new data in cancer vaccines. According to recent research from the United States, "HLA class...

Scientists at University of Tubingen, Department of Internal Medicine II describe research in cancer vaccines immunology.(Report)
September 22, 2008... Research findings, 'Generation of antigen-specific CTL responses using RGS1 mRNA transfected dendritic cells,' are discussed in a new report. "Advances in tumor immunology and Identification of tumor-associated antigens (TAAs) provide a basis...

Research on cancer vaccines immunotherapy detailed by scientists at National Institutes of Health.
September 22, 2008... Data detailed in 'Synergizing radiation therapy and immunotherapy for curing incurable cancers. Opportunities and challenges' have been presented. "The combination of radiation therapy and immunotherapy holds particular promise as a strategy...

Data on DNA vaccines detailed by researchers at Johns Hopkins Medical Institutions, Department of Pathology.(Report)
September 22, 2008... New research, 'Combination of treatment with death receptor 5-specific antibody with therapeutic HPV DNA vaccination generates enhanced therapeutic anti-tumor effects,' is the subject of a report. According to recent research from the United...

Research on immunology reported by scientists at University of Nijmegen, Nijmegen Center for Molecular Life Science.
September 22, 2008... Current study results from the report, 'Dendritic cell vaccination and immune monitoring,' have been published. According to recent research published in the journal Cancer Immunology, Immunotherapy, "We exploited dendritic cells (DC) to...

Research on melanoma vaccines discussed by scientists at Shizuoka Cancer Center.
September 22, 2008... Investigators publish new data in the report 'Novel approach to the characterization of melanoma associated-peptide-specific CTL lines from Japanese metastatic melanoma patients.' According to recent research from Shizuoka, Japan,...

Researchers from National Institutes of Health publish new studies and findings in the area of melanoma vaccines.
September 22, 2008... New investigation results, 'Treatment of metastatic melanoma using interleukin-2 alone or in conjunction with vaccines,' are detailed in a study published in Clinical Cancer Research. In this recent study, researchers in the United States...

National Non-Profit Organization Brings Cervical Cancer Awareness Walk to Big Apple.
September 22, 2008... Hundreds of women will join national non-profit organization, Tamika & Friends in New York City for its third Walk to Beat the Clock! to educate women and the men who care for them that cervical cancer is preventable. A first for the Manhattan...

Society of Gynecologic Oncologists to Host Cervical Cancer Prevention Forum.
September 22, 2008... The Society of Gynecologic Oncologists (SGO) is hosting a Cervical Cancer Prevention Forum on September 12-13, 2008 at the Hotel SAX in Chicago, IL. Approximately 50 key thought leaders will be in attendance to discuss the undefined areas of...

Vaccine against HER2-positive breast cancer offers complete protection in lab.
September 29, 2008... Researchers at Wayne State University have tested a breast cancer vaccine they say completely eliminated HER2-positive tumors in mice - even cancers resistant to current anti-HER2 therapy - without any toxicity (see also American Association...

DNA Vaccine Developed at the Karmanos Cancer Institute Fights HER2-Positive Cancers.
September 29, 2008... Researchers at the Barbara Ann Karmanos Cancer Institute and Wayne State University School of Medicine have developed a HER2 DNA vaccine that has shown to be effective on drug resistant tumors in mice. The study was reported in the September 15...

Researchers from University of Texas publish findings in cancer vaccines.
September 29, 2008... Scientists discuss in 'Health maintenance for postmenopausal women' new findings in cancer. According to recent research from the United States, "Menopause is the permanent cessation of menstruation resulting from the loss of ovarian and...

Researchers from California State University, Biology Department describe findings in life sciences.
September 29, 2008... Current study results from the report, 'Macrophage colony stimulating factor: not just for macrophages anymore! A gateway into complex biologies,' have been published. "Macrophage colony stimulating factor (M-CSF, also called colony stimulating...

KGI Offers Mammalian Cell Culture Program for Biotech Industry Professionals.
September 29, 2008... Keck Graduate Institute (KGI) announced that it will conduct a five-day program for industry professionals to learn the latest developments in mammalian cell culture, from November 2-7, 2008 (see also Biotech Business). "Mammalian cell...

Emerging Therapies, Including Bristol-Myers Squibb/Medarex's Ipilimumab, Will Drive Growth in the Malignant Melanoma Drug Market.
September 29, 2008... Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that the malignant melanoma drug market, driven by the launch of emerging agents, will experience robust annual 12...

Multi-Pronged Therapeutic Cancer Vaccine Regimen to be Studied in Melanoma Patients.(Clinical report)
September 29, 2008... Sanofi pasteur, the vaccines division of the sanofi-aventis Group, announced that it is sponsoring a Phase II clinical study exploring a multi-pronged treatment approach to high risk and advanced-stage melanoma -- an often fatal form of cancer...