Cancer Vaccine Week articles from October 2004

Cancer Vaccine Week archives from October 2004

Mammaglobin-A vaccine has therapeutic potential.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- A mammaglobin-A vaccine has potential as a treatment for certain breast cancers, results from a study in mice suggest. The breast cancer-associated antigen mammaglobin-A has been found in 80% of...

Strategies to improve dendritic cell cancer immunotherapy outlined.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Researchers outline strategies to improve dendritic cell-based immunotherapy against cancer in a recent issue of the Yonsei Medical Journal. "Dendritic cells (DCs) play a pivotal role in T...

Yeast-based immunotherapy causes mutation-selective tumor remission.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Ras-targeted, whole yeast-based immunotherapy resulted in mutation-selective tumor remission. "Activating mutations in Ras oncoproteins represent attractive targets for cancer immunotherapy, but...

Dendritic cell maturation drives Th1 polarization.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Dendritic cell maturation promoted by M1 and M4, end products of steroidal ginseng saponins metabolized in the digestive tract, drives Th1 polarization. "Ginseng is a medicinal herb widely used in...

Role of CD8+ T-cell immunity in progression of melanoma reviewed.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Researchers review the role of melanoma-specific CD8+ T-cell immunity in disease progression of advanced-stage melanoma patients in a recent issue of Clinical Cancer Research. According to...

Study says air worse in smoky bars than on truck-choked roads.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- If you're wondering whether a smoky bar or a city street filled with diesel truck fumes is more harmful to your health, you might want to skip your next happy hour. Smoky bars and casinos have up...

Animal models are guiding development of new immunotherapies for cancer.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Animal models are guiding the development of new immunotherapies for cancer. According to recent research published in the Journal of Leukocyte Biology, "Immunotherapy using adoptive cell transfer...

Ecopia selects four new compounds for further profiling.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Ecopia BioSciences, Inc., (EIA) announced the results of its discovery team's research over the last 5 months, which has led to the identification of 12 novel compounds. Four of the compounds have...

Paired iliac artery stent model helps determine drug-delivery device effect.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- A paired iliac artery stent rabbit model allows researchers to determine the effect of a new drug-delivery device. According to a study from France, "Preventing coronary in-stent restenosis is a...

Study finds few health effects on dogs exposed to September 11 terrorist sites.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Search-and-rescue dogs deployed after the 9/11 terrorist attacks suffered cuts and scrapes but no serious short-term effects from exposure to the disaster sites, according to research by the University...

Biologic therapy for brain cancers reviewed.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- A reseracher reviews biologic therapy for brain cancers in a recent issue of the Yonsei Medical Journal. According to a study from the United States, "The overall goal of our research projects is...

Autoantibodies to annexin XI-A, other autoantigens have biomarker potential.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Autoantibodies to annexin XI-A and other autoantigens have potential as biomarker of breast cancer, researchers report. F. Fernandez-Madrid, Wayne State University, and colleagues identified...

Brachytherapy applicator introduced for treating early-stage disease.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Varian Medical Systems (NYSE: VAR) announced the introduction of a new lightweight applicator for delivering postlumpectomy partial breast irradiation. The Advanced Breast Template System for...

Dense breast patterns evaluated with other risk factors of cancer.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Cancer epidemiologists in the U.K. "studied breast parenchymal patterns and 13 other potential risk factors for breast cancer in 172 breast cancer cases and 338 age-matched controls in Singapore." ...

Hedgehog signaling pathway is new therapeutic target for breast cancer.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Curis, Inc., (CRIS), a therapeutic drug-development company, announced that a recent journal article demonstrates that the Hedgehog signaling pathway is abnormally elevated in a series of human breast...

IDSI adds VP to commercialize laser mammography in global markets.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Imaging Diagnostic Systems, Inc., (IMDS) announced that Janusz Ostrowski has joined the company (IDSI) as vice president, international sales. Ostrowski will be responsible for implementing and...

Meta-analysis supports IGF-I and IGFBP-3 level link with premenopausal cancer.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Results of a meta-analysis suggest an association between levels of insulin-like growth factor (IGF)-I and IGF-binding proteins and development of premenopausal breast cancer. "IGFs are peptide...

New test discovers breast cancer at early, most treatable stage.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Doctors may soon have a new tool - a noninvasive, painless nipple fluid test - in their fight to make breast cancer a more treatable, nonfatal disease. Within the next couple years, women will be...

Noninvasive breast fluid tests aim to detect disease at most treatable stage.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Two companies are participating in the race to develop a screening technique for early-stage breast cancer based on testing breast fluid. IMI International Medical Innovations, Toronto, Canada, has...

Prolactin acts as a potent survival factor for human cell lines.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- The protein hormone prolactin, associated with stimulating lactation, protects human breast cancer cell lines from apoptosis, researchers in the U.K. report. Citing a large epidemiologic study of...

U.S. FDA grants review of post-tamoxifen drug for early breast cancer.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Novartis Oncology announced that its supplementary new drug application for Femara (letrozole) has been granted priority review by the U.S. Food and Drug Administration (FDA) for an indication in the...

Endoscopy company comments on Israeli Health Ministry committee report.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Given Imaging, Ltd., (GIVN) commented on a report issued by a committee appointed by the Israeli Ministry of Health to investigate the death of an Israeli patient several days following his ingestion of...

Enterprise renames itself.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- PhytoMedical Technologies, Inc., (PYTO), has successfully completed its name change from Enterprise Technologies, Inc. The new name more accurately reflects the company's entry into the research,...

PSA era is over for predicting prostate cancer risk, say Stanford researchers.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- The PSA test, commonly used as a screening tool for detecting prostate cancer, is now all but useless for predicting prostate cancer risk, according to Stanford University School of Medicine...

Tailored counseling may promote mammography among low-income rural black women.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Low-income older black women in rural areas of Arkansas who had never had a mammogram were more likely to do so after receiving a call from a community healthcare worker, University of Arkansas public...

Afraid that cancer will return, doctors treat "cure" like a four-letter word.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- There wasn't any doubt 6 years ago that Doug Jensen had cancer. The Oregon engineer's blood was clogged with the immature cells that are sure signs of leukemia. Treatment with a new wonder drug,...

Antibodies in tumor immunotherapy reviewed.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Researchers review antibodies in tumor immunotherapy in a recent issue of Expert Opinion on Biological Therapy. "The role of antibodies as therapeutic cancer vaccines includes two distinct...

Dendritic cell-based immunotherapy for cancer reviewed.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Researchers review dendritic cell-based immunotherapy for cancer in a recent issue of Transfusion Medicine Reviews. According to recent research from the United States, "The encouraging results...

Gene-engineered T cells are superior adjuvant therapy for cancer.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Gene-engineered T cells are a superior adjuvant therapy for metastatic cancer. According to a study from Australia, "The major limiting factor in the successful application of adjuvant therapy for...

Heat shock proteins reviewed.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Researchers review heat shock proteins in a recent issue of Immunology Letters. "The contribution of major histocompatibility complex (MHC) I and II to the adaptive immune response has been well...

Ubiquitin-fusion degradation pathway plays key role in DNA vaccination.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- The ubiquitin-fusion degradation pathway plays an indispensable role in naked DNA vaccination with a chimeric gene encoding a syngeneic cytotoxic T lymphocyte epitope of melanocyte and green fluorescent...

Defective gene thwarts cell talk, leading to breast and ovarian cancers.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Scientists have recently discovered that the gene EDD is implicated in the development of breast and ovarian cancer. "Cancer arises from defects in cell growth and division. We are now beginning to...

Alemtuzumab may have a role in inducing important cardiac side effects.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Cardiac toxicity of alemtuzumab in patients with mycosis fungoides/Sezary syndrome "Alemtuzumab is a monoclonal antibody to CD52 that has activity in T-cell leukemia and lymphoma. This study alms to...

Development of therapeutic nucleic acids is ongoing.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Researchers with the U.S. National Cancer Institute recently provided an overview on the development of therapeutic nucleic acids to target cervical cancer. "Cervical cancer is the second most...

Interlaboratory results support Hybrid Capture 2 HPV test's reliability.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Interlaboratory results show Digene's Hybrid Capture 2 test is reliable for detecting human papillomavirus DNA in liquid cytology specimens. Researchers at the U.S. National Cancer Institute and at...

Mathematical model supports U.K. screening interval recommendations.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- A mathematical model of cervical human papillomavirus infection and cancer in the U.K. supports recently revised cervical cancer screening interval recommendations. According to a paper published...

Non-European HPV type 16 variants more frequent in invasive disease.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- A study from Italy found non-European variants of human papillomavirus type 16 occurred more frequently in invasive cervical cancer lesions than European variants. "Human papillomavirus type 16...

Study reports "pronounced" chromosomal instability in advanced disease.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Biophysicists in Norway report finding "pronounced" chromosomal instability in advanced cases of cervical cancer. "Intratumor heterogeneity in chromosomal aberrations is believed to represent a...

Upregulation of uPA by HER-2/neu appears to occur in early stage disease.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Upregulation of urokinase plasminogen activator by the HER-2/neu oncogene appears to occur in the early stage of cervical cancer in patients, according to recent research. "It has been suggested...

The flagellar motor controls exopolysaccharide expression in V. cholerae.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- There is a complex relationship between the flagellum-dependent exopolysaccharide (EPS) signaling cascade and virulence in a mouse model. According to recent research published in the Journal of...

Companies initiate phase IIIb clinical trial of Tarceva in advanced NSCLC.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Genentech, Inc., (DNA) and OSI Pharmaceuticals, Inc., (OSIP) announced the initiation of a phase IIIb clinical study of the investigational therapy Tarceva (erlotinib HCl) in patients with second- and...

Diagnostics company enters broad diagnostic collaboration with Compugen.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Diagnostic Products Corp. (DP) and Compugen, Ltd., (CGEN) announced a broad collaboration for the development and commercialization of novel diagnostic products, with an anticipated focus in the cancer...

Strong association of ARK5 with tumor invasion and metastasis.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- There is a strong association of ARK5 with tumor invasion and metastasis. According to a study from Japan, "We recently identified a novel human AMPK family member, ARK5, and discovered that is a...

Direct protein microarray detection strategies reviewed.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Scientists review direct protein microarray detection strategies in a recent issue of the Journal of Immunological Methods. "Protein microarrays are being utilized for functional proteomic...

Minimal residual disease assessment predicts survival and relapse in AML.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Minimal residual disease assessment predicts survival and relapse in acute myeloid leukemia. "Outgrowth of minimal residual disease (MRD) in acute myeloid leukemia (AML) is responsible for the...

Vaginal, cervical cancer differentiated by cluster analysis of protein patterns.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Cluster analysis of proteomics data differentiates among normal vaginal mucosa, primary vaginal and primary cervical cancer "Protein patterns in six samples from primary vaginal cancers, in five...

Chlamydia trachomatis associated with invasive cervical cancer.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Results of an international study show an association of Chlamydia trachomatis with invasive cervical carcinoma regardless of human papillomavirus status. J.S. Smith and colleagues at the...

Mini organ cultures of human epithelia can be used in ecogenotoxicology.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Mini organ cultures (MOCs) are a suitable in vitro model for assessing genotoxic effects of environmental pollutants both after single or repetitive exposure. "The carcinogenic potential of...

Src family of tyrosine kinases important for embryonic stem cell self-renewal.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- The Src family of tyrosine kinases is important for embryonic stem cell self-renewal. "cYes, a member of the Src family of non-receptor tyrosine kinases, is highly expressed in mouse and human...

RBX approved for reimbursement in China, eligible for grants.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Genex Pharmaceutical, Inc., (GENX), a Delaware corporation, is a biomedical technology company with a new product for treating various bone-related injuries called Reconstituted Bone Xenograft (RBX), a...

Tissue Connect's parent discloses insider buying.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Consortium Service Management Group, Inc., (CTUM) said that directors and insiders have purchased 470,795 shares of the company's common stock in 17 separate transactions since the beginning of 2004....

Excess GM1-ganglioside in brain cells triggers neurodegeneration, retardation.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Excess accumulation in brain cells of a fat molecule called GM1-ganglioside (GM1) disrupts the folding of newly assembled proteins into their proper shapes, triggering nerve degeneration and mental...

Acidic polysaccharides may inhibit H. pylori adhesion to gastric cells.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Acidic polysaccharides from plants may play a role in inhibiting Helicobacter pylori adhesion to gastric host cells. "H. pylori specifically adheres to host cells, mainly based on...

HIV specialists and oncologists differ in pain management and palliative care.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- HIV specialists and oncologists differ in their opinions of pain management and palliative care. "Despite the introduction of HAART, pain is still a common symptom in people living with HIV/AIDS....

Simple model simulates cellular changes in T cells following HIV-1 infection.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- A simple model simulates cellular changes in T cells following HIV-1 infection. "A new mathematical model is presented to simulate various changes of cell pools in the T cell immune system with...

Interstitial photodynamic therapy is effective for some head and neck cancer.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Interstitial photodynamic therapy (IDPT) is a useful tool for palliation of recurrent head and neck cancers. According to a study from England, "IPDT is a technique for applying photodynamic...

MALT lymphoma occurs in an animal model of H. heilmannii infection.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Animal model enables researchers to manipulate experientially the presence of Helicobacter heilmannii infection. According to recent research published in the Journal of Pathology, "While...

Post-transcriptional regulator of KSHV controls gene expression through IRES.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- A posttranscriptional regulator of Kaposi sarcoma-associated herpesvirus controls gene expression through the internal ribosome-entry site. According to recent research from Japan, "Kaposi's...

HPV 16 L2E6E7 booster vaccine elicits immune response.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- An HPV 16 L2E6E7 booster vaccine elicited an immune response in vulval intraepithelial neoplasia patients previously vaccinated with TA-HPV (vaccinia virus encoding HPV 16/18 E6E7). "Heterologous...

HPV type 16 L1 virus-like particle vaccine may prevent infection.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- A human papillomavirus (HPV) type 16 L1 virus-like particle vaccine shows promise for protection against HPV16 infection. "A post hoc analysis was performed using combined data from two Phase I...

Gamma-delta T cells expressing chimeric receptors offer antitumor control.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Gamma-delta T cells expressing chimeric receptors offer antitumor control. According to recent research from Germany, "human peripheral blood gamma-delta T cells (Vgamma9+ Vdelta2+) can be...

Expanded family of class II cytokines share IL-10 receptor-2 (IL-10R2) chain.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Scientists describe the expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain in a recent issue of the Journal of Leukocyte Biology. "Several novel interleukin...

Peptide derived from eosinophil-derived neurotoxin induces apoptosis in KS cells.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- A synthetic peptide derived from eosinophil-derived neurotoxin induces apoptosis in Kaposi sarcoma cells. "Several commercial preparations of human chorionic gonadotropin (hCG) have been tested as...

The Na+-citrate transporter CitS of K. pneumoniae has a pore loop structure.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Researchers describe a model in which part of the cytoplasmic loop containing Cys-398 and Cys-414 folds back into the translocation pore as a pore-loop structure. According to published research...

New linear RNA amplification protocol works with very small samples.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Affymetrix Inc.'s high-density oligonucleotide microarray analysis protocol that includes a linear amplification step has use in situations where RNA recovery is very low, pathologists report. ...

Program for ill Hanford workers improved but still criticized by senators.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- The federal Department of Labor has improved its processing of claims by ill workers at the Hanford nuclear site, according to a study by the federal Government Accountability Office (GAO). The...

Anticancer drug HGS-ETR1 advances to phase II clinical development.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Human Genome Sciences, Inc., (HGSI) announced that it has begun dosing patients in a phase II clinical trial of HGS-ETR1 (agonistic human monoclonal antibody to TRAIL Receptor 1) in patients with...

Fibronectin may stimulate human lung carcinoma cell growth.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Signaling through specific matrix-binding betaI integrins resulting from exaggerated deposition of fibronectin in the lungs might promote lung carcinoma cell growth. "Tobacco use is the most...

Study finds volatile biomarkers in lung cancer blood.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Hexanal and heptanal concentrations in breath originate from blood, making screening of lung cancer by breath analysis feasible, researchers say. According to a study from the People's Republic of...

U.S. patent for rapid nucleic acid amplification awarded to university.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- The U.S. Patent and Trademark Office has issued the University of Utah U.S. Patent No. 6,787,338 (the '338 patent) relating to methods of rapid nucleic acid amplification. The issuance of this...

Five dose levels of monoclonal antibody melanoma vaccine compared.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Researchers report the results of a phase II trial comparing five dose levels of BEC2 anti-idiotypic monoclonal antibody vaccine that mimics GD3 ganglioside in a recent issue of the journal Vaccine. ...

GD3-L-KLH vaccine elicits antibody response in melanoma patients.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Sequential immunization of melanoma patients with GD3 ganglioside vaccine and anti-idiotypic monoclonal antibody that mimics GD3 ganglioside elicited an antibody response that did not correlate with...

Hampton Berkshire Insurance to acquire cancer-focused pharmaceutical.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Hampton Berkshire Insurance & Financial, Inc., (HBIF), a Nevada corporation, announced that it has signed a definitive acquisition agreement to acquire Innovate Oncology, Inc., a Delaware corporation...

Pharma company completes sale of vaccines business to ID Biomedical.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Shire Pharmaceuticals Group plc (Shire) (LSE: SHP, NASDAQ: SHPGY, TSX: SHQ) and ID Biomedical Corporation (ID Biomedical) (TSX: IDB; NASDAQ: IDBE) announced that they have closed the sale of Shire's...

Early intensive therapy beneficial for primary resistant myeloma patients.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Early intensive therapy is beneficial in patients with primary resistant myeloma. "Clinical outcomes were evaluated in 89 consecutive patients with multiple myeloma that had not responded to...

EGFR-1 not a prognostic indicator in advanced primary ovarian epithelial cancer.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Epidermal growth factor receptor 1 overexpression doesn't appear to have prognostic value in advanced primary ovarian epithelial cancer, pathologists in France report. "Epidermal growth factor...

Lower ERbeta and PR immunoreactivity observed in cancerous epithelial tissue.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Epithelial cells in ovarian cancer tissue had significantly lower estrogen receptor beta and progesterone receptor immunoreactivity than normal ovarian tissue in a study from Sweden. ...

Novel target found for detecting ovarian cancer in blood.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Scientists have discovered a new way to detect ovarian cancer in the blood. Reporting in the September 15, 2004, issue of Cancer Research, Fox Chase Cancer Center, Philadelphia, researchers explain...

Potential biomarkers identified by gene expression technique.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Potential biomarkers of ovarian cancer have been identified by gene expression analysis. "In this study, the gene expression of 20 ovarian carcinomas, 17 ovarian carcinomas metastatic to the...

Evanston Northwestern Healthcare promotes breast cancer early detection.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- TouchVision, Inc., a wholly owned subsidiary of Trinity Learning Corp. (TTYL), announced that Evanston (Illinois) Northwestern Healthcare (ENH) has deployed the MyGenerations breast cancer risk...

Cancer-focused biotech company names Randall B. Riggs VP of business development.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- TransMolecular, Inc., an oncology focused biotechnology company, has appointed Randall B. Riggs to the new position of vice president, business development. Riggs will be responsible for managing...

Studies of polyamines could extend their application to cancer diagnosis and treatment.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Polyamines may play a role in cancer diagnosis and treatment. According to a study from Israel, "The naturally occurring polyamines, spermine, spermidine, and the diamine putrescine, are widespread...

FDA accepts Entereg (alvimopan) NDA for review.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Adolor Corp. (ADLR) and GlaxoSmithKline (GSK) announced that the U.S. Food and Drug Administration (FDA) has accepted for review the new drug application (NDA) for Entereg (alvimopan) capsules. ...

Companies announce revision of licensing agreement for cancer cell line vaccines.
October 4, 2004... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- The Immune Response Corporation (IMNR), a biopharmaceutical company, and NovaRx Corporation, a privately held cancer-focused company, have signed a licensing agreement to transfer all of The Immune...