Cancer Vaccine Week articles from November 2004

Cancer Vaccine Week archives from November 2004

Biotech company receives $3 million NCI award for anticancer vaccine protein.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Stellar Biotechnologies, Inc. has been awarded $3 million from the National Cancer Institute of the [U.S.] National Institutes of Health for the development of production methods, quality standards, and...

Chemotherapy after vaccination benefits glioblastoma patients.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Chemotherapy after vaccination was beneficial in glioblastoma multiforme patients. According to recent research published in the journal Clinical Cancer Research, "Although the development of...

Raf kinase expression increases mortality of influenza-infected mice.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Lung-specific expression of active Raf kinase results in increased mortality of influenza A virus-infected mice. According to published research from Germany, "Alterations in signaling via the...

HPV type 18 L1 VLP vaccine safe and immunogenic in women.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Results from a phase I study indicated a human papillomavirus (HPV) type 18 L1 VLP vaccine was safe and immunogenic in women. "Human papillomavirus (HPV) infection can cause genital warts and...

Dendritic cell vaccine boosts T cell-mediated immunity to tyrosinase.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Vaccinia virus-transduced, CD34+-derived dendritic cell vaccination boosted T cell-mediated immunity to tyrosinase. Six American Joint Committee on Cancer stage IV melanoma patients were enrolled...

Loss of clone with FLT3 gene mutation at relapse does not improve AML prognosis.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- The loss of a clone with an FLT3 gene mutation at relapse does not improve the prognosis of acute myeloid leukemia. According to recent research from Germany, "Internal tandem duplications (ITDs)...

Slightly increased risk of ischemic stroke found with tamoxifen.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Researchers at Duke University Medical Center have found a slightly elevated risk of ischemic stroke due to a blood clot in the brain in patients treated with tamoxifen, a drug commonly prescribed both...

Oral fluconazole safe/effective empiric treatment for neutropenic fever.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Oral fluconazole is a safe and effective empiric treatment for persistent neutropenic fever. According to a study from Israel, "Neutropenic patients who continue to be febrile despite adequate...

Antiestrogenic drug combinations may be used for glioblastoma malignancies.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Antiestrogenic drug combinations may be used for glioblastoma malignancies. According to researchers in Turkey, "The antitumor activity of nonsteroidal antiestrogens on C6 and low passage of human...

CD45 plays significant role in nuclear apoptosis by chloride channel regulation.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- CD45 plays a significant role in nuclear apoptosis by chloride channel regulation. According to published research from Canada, "Mitochondrial-perturbating agents such as toxic compounds induce...

Humic acid induces apoptosis in premyelocytic leukemia HL-60 cells.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Humic acid induces apoptosis in promyelocytic leukemia HL-60 cells. According to a study from Taiwan, "It has been shown that humic acid (HA), a phenolic polymer, exhibits pro-oxidant and cytotoxic...

Gli proteins up-regulate expression of basonuclin in basal cell carcinoma.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Gli proteins up-regulate the expression of basonuclin in basal cell carcinoma. "Tumorigenesis is frequently accompanied by enhanced rRNA transcription, but the signaling mechanisms responsible for...

Androgen receptor expression inversely correlates with pathologic, tumor stage.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Androgjen receptor expression is inversely correlated with pathologic, tumor stage in bladder cancer. Researchers in the United States conducted a study "to evaluate the expression of the androgen...

New risks for bladder cancer identified by MIT team.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- MIT researchers and colleagues have identified three new chemical risk factors for bladder cancer in a study involving some 600 people in the Los Angeles area. The work was reported in the Journal...

Positive cancer data on ECO-4601 presented at symposium.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Ecopia BioSciences, Inc., (EIA) presented data on ECO-4601 in a poster entitled "A new antitumor compound, ECO-4601: Preclinical evaluation and in vivo efficacy in glioma" at the European Organization...

Protein protecting brain from toxins also blocks some chemotherapy.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- St. Jude studies showing that Mrp4 limits penetration of topotecan suggest that blocking this protein might increase access of anticancer drugs to tumor sites and improve treatment of brain cancer ...

Breast density, second breast cancer in women with ductal carcinoma studied.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Having highly dense breasts may be associated with an increased risk of a second breast cancer among women who have had a ductal carcinoma in situ (DCIS), according to a study in the October 6 issue of...

CORI calls for increased awareness of link between obesity, breast cancer.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Statistics from the American Obesity Association show that obese women are more likely to die of breast cancer than women of healthy weight and that after menopause these women have a higher risk of...

Exercise boosts recovery from cancer.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Women should aim for 1/2 hour of gentle exercise three times a week to aid their recovery from breast cancer, according to early results presented October 7, 2004, at a University of Bristol conference...

Fertility concerns affect treatment decisions of many young women with cancer.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Concern about infertility resulting from breast cancer therapy influenced treatment decisions in nearly one-third of young patients participating in a recent study. The study - the largest to date...

Grant enables study on cancer screening promotion.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- For one University of Georgia professor, research means the most fundamental of all differences: the difference between life and death. Three years ago Jeffrey K. Springston, associate professor in...

Healthy women need better understanding of disease incidence, risk factors.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Results of a study in Germany suggest healthy women need a better understanding of breast cancer incidence and risk factors. According to U.G. Pohls and colleagues, "The efficacy of early breast...

In vitro, arachidonic acid release may mediate tamoxifen, raloxifene actions.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "Tamoxifen is being used successfully to treat breast cancer. However, tamoxifen also increases the risk of developing endometrial cancer in postmenopausal...

Soy isoflavones in food, rather than pure form, better for ER-dependent disease.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Soy isoflavones in food, i.e., soy flour-containing foods, rather than isoflavones in pure form are better for women with estrogen-dependent breast cancer, recommend nutritionists at the University of...

Specific vitamin D receptor gene polymorphisms associated with higher risk.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Researchers in the U.K. have identified specific vitamin D receptor gene polymorphisms that appear to be associated with breast cancer risk. "The steroid hormone 1,25-dihydroxyvitamin D is thought...

Study: Oleic acid could be a potential initiating carcinogen after epoxidation.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- University of Illinois researchers say oleic acid could be a potential initiating carcinogen after epoxidation of 17beta-estradiol, a mechanism they previously suggested results in breast cancer...

Well-differentiated breast tumors have more 16q loss than poorly differentiated.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Well-differentiated breast tumors have more 16q loss than poorly differentiated tumors. According to a study from the Netherlands, "Loss of heterozygosity (LOH) at the long arm of chromosome 16 is a...

Cancer research foundation announces new partnership.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- The Lance Armstrong Foundation (LAF) has announced a 5-year, $500,000 gift to the Nevada Cancer Institute (NVCI) to establish the Lance Armstrong Foundation Survivorship Center at the Institute. The new...

Company changes name and prepares for HIV vaccine trial.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Research company Merix Bioscience announced the change of its name to Argos Therapeutics, Inc. Additionally, the company stated that it is preparing for an HIV clinical trial with Argos' proprietary...

Contract research organization opens office in top German biotech region.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- INC Research has opened an office in Germany, in Dusseldorf's Life Science Center. INC Research strategically located its facility in the North Rhine-Westphalia region of Germany, to be in close...

Partnership formed to market phase 3 chemoprotective agent in North America.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Takeda Pharmaceutical Company Limited has entered into an alliance agreement with U.S. based BioNumerik Pharmaceuticals, Inc., to market Tavocept (dimesna), a phase 3 chemoprotective agent developed by...

American Indian summit aims to raise cancer awareness.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Health statistics show that once diagnosed with cancer, American Indians have a lower 4-year survival rate than any other group in the country. Organizers of the Northern Plains American Indian...

Leukemia society awards two $5 million grants to develop anticancer therapies.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- The Leukemia & Lymphoma Society awarded two Specialized Center of Research (SCOR) grants, bringing funding for the program, the society's most synergistic research initiative, past $77 million in the 5...

Rates of advanced breast cancer lower in The Netherlands due to mammography.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Public health specialists in The Netherlands credit the country's breast cancer screening program with reducing incidence of advanced disease. "The effect of the implementation of the Dutch breast...

Pharmaceutical company enters licensing agreement to develop oral cancer drug.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- IVAX Corporation (IVX) has entered into a licensing agreement with Nippon Shinyaku to develop and market HMN-214, a polo-like kinase inhibitor that targets pancreatic, prostate, and a number of other...

Data released on two spectrum selective kinase inhibitors: XL647, XL999.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Exelixis, Inc., (EXEL) released data at the 16th annual meeting of the European Organization for the Research and Treatment of Cancer (EORTC) in Geneva, Switzerland for two of its receptor tyrosine...

Data supports value of prostate brachytherapy.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Recent data from a 12-year follow-up of more than 1,500 patients showed brachytherapy as a powerful treatment for prostate cancer. Dr. Louis Potters, medical director of the New York Prostate...

Energy blocker kills big tumors in rats.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Building on their earlier work, Johns Hopkins researchers have discovered that an apparently nontoxic cellular "energy blocker" can eradicate large liver tumors grown in rats. Six months to more than a...

Fruit and veg extract enhances cancer drug.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- A food extract could be used to improve the effects of an established cancer drug, scientists report. The drug, mitomycin C (MMC), is a well-known anticancer treatment used mainly against solid...

Normal cells in tumors may aid cancer growth.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Normal cells that live among the cancer cells in a tumor may not be the innocent bystanders they are usually assumed to be. A study led by researchers at the Ohio State University Comprehensive...

Tumor regression reported with AP23573 in relapsed, refractory cancer.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Ariad Pharmaceuticals, Inc., (ARIA) announced, for the first time, updated results of two phase I clinical trials of its novel mTOR inhibitor, AP23573 as a single agent, showing documented tumor...

Screening recommendations are met in only a few European countries.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Researchers with the Finnish Cancer Registry surveyed 25 cancer screening centers in 18 European countries and found that only a few follow recommended guidelines. According to A. Anttila and...

Socioeconomic disparities affect disease incidence and mortality in U.S.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Researchers with the U.S. National Cancer Institute (NCI) have identified time-related area socioeconomic disparities that affect cervical cancer incidence and mortality in the U.S. "Temporal...

Absolute guidelines needed for monitoring minimal residual disease in CML.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Absolute guidelines are needed for monitoring minimal residual disease in chronic myeloid leukemia. According to recent review in the journal Hematology, "Detection and monitoring of minimal...

Alliance to develop novel anticancer compound.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- ImmunoGen, Inc., (IMGN) and Biogen Idec, Inc., (BIIB) announced that Biogen Idec has licensed exclusive rights to use ImmunoGen's proprietary Tumor-Activated Prodrug (TAP) technology with antibodies to...

CoFactor results reported showing antitumor activity, lower systemic toxicity.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Adventrx Pharmaceuticals, Inc., (ANX) announced the results of recent preclinical studies demonstrating enhanced antitumor activity with lower systemic toxicity in a mouse model for colorectal cancer...

Glutathione-S-transferase P1-1 may have role in early colon cancer.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Glutathione-S-transferase P1-1 may have role in early colon cancer. According to recent research from Japan, "aberrant crypt foci, precursors of colonic adenoma, are frequently positive for...

ZD9331 has minimal antitumor activity as 2[superscript]nd/3[superscript]rd line colorectal cancer therapy.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- ZD9331 yields minimal antitumor activity as a 2[superscript]nd or 3[superscript]rd line colorectal treatment. "This study investigated the efficacy, and tolerability of ZD9331 as second- or...

p53-dependent transcription exhibits on and off responses after genotoxic stress.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- p53-dependent transcription exhibits both on and off responses after genotoxic stress. According to published research from Estonia, "The p53 protein is a central player in cellular response to DNA...

Gene silencing, posttranscriptional regulation studied in ocular melanoma.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Epigenetic silencing of the CIITA gene and posttranscriptional regulation of class II MHC genes was studied in ocular melanoma cells. "Primary uveal melanocytes and many ocular melanoma cells are...

Anticancer compound inhibits growth in drug resistant cell lines, company says.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Tapestry Pharmaceuticals, Inc. (TPPH) announced that in vitro studies show that its novel anticancer compound TPI-273 shows inhibitory activity in a variety of tumors, exceeding the potency of...

Novel antiapoptotic protein X-linked IAP antagonists potential cancer therapy.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Novel antiapoptotic protein XIAP antagonists are a potential therapy for cancers overexpressing X-linked IAP. "Inhibitor of apoptosis (IAP) proteins are overexpressed in many cancers and have been...

Novel compounds exhibit antiviral and antitumor effects.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Novel compounds exhibit antiviral and antitumor effect. Novel platinum compounds and antiviral guanosine-type ligands are antiviral/antitumor. According to a study from Italy, "Platinum...

Study results of treatment for leukemia with arsenic trioxide presented.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- An Iranian investigational study of single-agent arsenic trioxide for the treatment of acute promyelocytic leukemia (APL) was presented at the 16th Annual meeting of the European Organization for...

U.S. FDA grants orphan status to drug for treatment of soft tissue sarcoma.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- The United States Food & Drug Administration (FDA) has granted Orphan Drug Designation to Yondelis in the indication of soft tissue sarcoma (STS). The sponsor of this application in the U.S. is...

Health officials brief families on Pratt & Whitney cancer study.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Researchers say they will need nearly 3 more years to determine if the rate of brain cancer cases is above normal at jet-engine maker Pratt & Whitney. Gary Marsh, a biostatistician at the University...

EBV is integrated between REL and BCL-11A in American Burkitt lymphoma cell line.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Epstein Barr Virus is integrated between REL and BCL-11A in the American Burkitt lymphoma cell line. "Epstein-Barr virus (EBV) initially isolated from the cultured Burkitt lymphoma (BL) cells, is...

Company announces clinical hold on TNFerade trials.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- GenVec (GNVC) announced that the U.S. Food and Drug Administration (FDA) has requested that clinical trials of TNFerade be placed on hold, pending review of information pertaining to a potential...

High serum SCC Ag predicts poor survival in esophageal cancer with esophagectomy.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Elevated serum levels of squamous cell carcinoma antigen predicts poor survival in advanced esophageal cancer after esophagectomy. According to recent research published in the World Journal of...

American Stock Exchange lists common stock oncology company.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- The American Stock Exchange (Amex) listed the common stock of YM BioSciences, Inc., under the ticker symbol YMI. YM BioSciences, Inc., is a cancer drug development company. Its lead drug,...

Cancer-focused bioscience company reports Q3 financials, operating highlights.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Ecopia BioSciences Inc. (EIA) reviewed recent operating highlights and announced its financial results for the third quarter ended August 31, 2004. Ecopia presented a poster with preclinical data,...

Grape seed flavonoids have exhibited antioxidant activity in a number of studies.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- A recent review focused on health aspects of functional grape seed constituents. Investigators in the United States report, "Functional ingredients of grape seeds include several flavonoids with a...

Expression of 7 ARP2/3 complex genes are decreased in gastric cancer.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- The expression of 7 ARP2/3 complex genes are decreased in gastric cancers. "The Arp2/3 complex and filamins play important roles in organization of actin cytoskeleton, and thus in cellular...

KiSS-1 downregulation causes tumor invasion/worse prognosis in gastric cancer.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- KiSS-1 downregulation causes tumor invasion and a worse prognosis in gastric cancer. According to recent research from Japan, "KiSS-1 is a promising candidate tumor-suppressor gene and may play a...

Independent component analysis of microarray data applied to endometrial cancer.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- According to published research from England, "Gene microarray technology is highly effective in screening for differential gene expression and has hence become a popular tool in the molecular...

Inconsistent psychosocial outcomes among cancer services thwart comparison.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- A study comparing psychosocial outcomes of genetic counseling for familial cancers among five U.K. centers found the results too inconsistent to identify significant factors affecting service provision....

Lymphocyte activation occurs early in invasive endometrial, cervical cancer.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- According to a study from Greece, "Major histocompatibility complex (HLA system) class II molecules including HLA-DR antigens, associate with peptides, which are derived from antigens, for presentation...

P53 codon 72 polymorphism increases risk of ovarian and endometrial cancers.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- According to recent research from Greece, "The polymorphism of codon 72 in the p53 tumor suppressor gene has been associated in the last decade with the risk of developing various neoplasias. "An...

Tumorigenesis by HHV-8 chemokine receptor vGPCR is accelerated by HIV-1 Tat.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Tumorigenesis by the HHV-8 chemokine receptor vGPCR is accelerated by HIV-1 Tat. According to a study from the United States, "Human herpesvirus 8 (HHV-8), also called Kaposi's sarcoma (KS)...

Leukemia-associated Rho GEF factor helps regulate early hematopoiesis stages.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- The leukemia-associated Rho GEF factor helps regulate the early stages of hematopoiesis. According to published research from Russia, "Guanine nucleotide exchange factors (GEFs) of the Dbl family...

Drug receives orphan designation.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Medarex (MEDX) announced that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation to Medarex's fully human anti-CD30 antibody, MDX-060, for the treatment of Hodgkin's...

Study finds no association between HRT use and risk of lymphomas, myelomas.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Pharmacologists in Italy have found no association between postmenopausal use of hormone replacement therapy (HRT) and risk of developing lymphomas and myelomas. The existence of such a relationship...

Lung image database consortium established for medical imaging researchers.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Lung image database consortium has been established for medical imaging research community. "To stimulate the advancement of computer-aided diagnostic (CAD) research for lung nodules in thoracic...

Cancer center utilizes new CT technology.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Siemens (SI) announced that the University of Texas M. D. Anderson Cancer Center will acquire five new CT systems, which will be installed in the new Ambulatory Care Building at the M.D. Anderson Cancer...

Isolated case of pulmonary KS in pregnancy reported.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Physicians at Northwestern University's Feinberg School of Medicine have described the first reported case of isolated pulmonary Kaposi's sarcoma in pregnancy. "Kaposi's sarcoma in human...

Estrogen plays a critical role in female hepatocarcinogenesis.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Estrogen plays a critical role in female hepatocarcinogenesis. According to researchers in Japan, "Estrogen has been related to the development of hepatocellular carcinoma (HCC). "In this...

Laser-induced thermotherapy effective in lung metastases and primary lung tumors.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Laser-induced thermotherapy is effective in lung metastases and primary lung tumors. According to a study from Germany, "We present laser-induced thermotherapy (LITT) of primary and secondary lung...

Photodynamic and brachytherapy show good results for endobronchial tumor control.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Sequential photodynamic therapy and high-dose brachytherapy for endobronchial tumor control in patients with limited bronchogenic carcinoma. According to a study from the United States, "bulky...

T cells needed early in ASCT to induce a graft-versus-lymphoma effect.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- T cells are needed early in autologous stem cell transplantation in order to induce a graft-versus-lymphoma effect. According to recent research published in the journal Bone Marrow...

Expression of cytokeratin by malignant meningiomas can be a diagnostic pitfall.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Expression of cytokeratin by malignant meningiomas can be a diagnostic pitfall for confusing a malignant meningioma with a metastatic carcinoma. "Based on clinical and histologic features,...

B-RAF is therapeutic target in melanoma.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- B-RAF is a therapeutic target in melanoma. According to a study from England, "B-RAF is a serine/threonine-specific protein kinase that is mutated in approximately 70% of human melanomas. However,...

CombiMatrix to acquire 33% of oncology drug developer.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Acacia Research Corp. (ACTG) announced that its CombiMatrix group has entered into an agreement to acquire one-third ownership of Leuchemix, Inc., a private drug-development firm which is developing...

U.S. FDA grants Aplidin orphan drug status for the treatment of multiple myeloma.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- PharmaMar announced that Aplidin, its second marine-derived compound in phase II clinical development, has been granted orphan drug status by the United States Food and Drug Administration (FDA), for...

Novel method assesses DNA damage after exposure to benzo(a)pyrene.
November 1, 2004... 2004 NOV 1 - (NewsRx.com & NewsRx.net) -- A novel method is used to assess DNA damage after exposure to benzo(a)pyrene. According to recent research from Spain, "Genotoxins present in the aquatic environment are often associated with the...