Cancer Vaccine Week articles from January 2003

Cancer Vaccine Week archives from January 2003

Dendritic cells generated by Flt3L or GM-CSF/IL-4 generate antileukemia response.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "Bone marrow (BM)-derived dendritic cells (DCs) cultured in granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin 4 (1L-4) have been used to generate antitumor immune responses....

Precursors of leukemic dendritic cells are identified.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from France, "dendritic cells (DC) can facilitate immune responses that might help in the induction of effective antitumor T cell responses. We reported previously that...

Chimeric receptor appears to augment T cell immunity against tumors.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from Australia, "a new strategy to improve the therapeutic utility of redirected T cells for cancer involves the development of novel antigen specific chimeric receptors capable of...

Postoperative chemoradiation results in satisfactory survival rates.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "The 5-year survival of patients with completely resected node-positive gastric cancer ranges from 15% to 25%. We explored the feasibility of a chemoradiation regime consisting of concomitant...

Preliminary phase I data released on OncoVEX.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- BioVex announced preliminary phase I results from the clinical trial of its lead oncology product candidate, OncoVEX (GM-CSF) in patients with breast cancer and melanoma. OncoVEX (GM-CSF) is the...

Recombinant therapy could sensitize cancer cells to retinoic acid.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Researchers think recombinant gene therapy to induce receptor expression in cancer cells could enhance the effectiveness of retinoic acid against certain...

Trial to test new drug to boost immune system after chemotherapy.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- The Kimmel Cancer Center at Thomas Jefferson University in Philadelphia is the first center in the nation to open enrollment in a clinical trial aimed at testing the effectiveness of a new drug to help...

Trans-signalling via the agonistic soluble IL-6 receptor in human diseases.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "The activation of cells that do not express the membrane bound interleukin-6 receptor (IL-6R) by IL-6 and the soluble IL-6 receptor (sIL-6R) is termed trans-signalling. Trans-signalling may be a...

Methotrexate polyglutamation may lack prognostic significance.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "The purpose of this study was to determine if a correlation exists between clinical outcome and accumulation and polyglutamation of methotrexate by lymphoblasts in vitro in children with B-cell...

Nitric oxide synthase inhibitors enhance vascular targeting.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- Researchers have learned that different varieties of nitric oxide synthase inhibitors can enhance tumor targeting by antivascular agents. "This study investigated the enhancement of the vascular...