Cancer Vaccine Week articles from December 2008

Cancer Vaccine Week archives from December 2008

Data on cancer vaccines detailed by J.B. Hansen and co-authors.
December 1, 2008... "The ability to regulate the cellular homeostasis of a higher organism through tight control of apoptosis and cell division is crucial for life. Dysregulation of these mechanisms is often associated with cancerous phenotypes in cells,"...

New cancer vaccines research reported from K.E. Lasser and co-authors.
December 1, 2008... According to a study from the United States, "Elderly minority patients are less likely to receive influenza vaccination and colorectal cancer screening than are other patients. Communication between primary care providers (PCPs) and patients...

Research from L.M. Kollar and co-researchers yields new findings on cancer vaccines.
December 1, 2008... According to recent research published in the journal Current Opinion in Obstetrics & Gynecology, "Purpose of review The purpose of this article is to review recent literature that may help guide the development of effective, evidence-based...

Research on cancer vaccines reported by A. Berntsen et al.
December 1, 2008... "Therapeutic dendritic cell (DC) vaccination against cancer is a strategy aimed at activating the immune system to recognize and destroy tumor cells. In this nonrandomized phase 1/2 trial, we investigated the safety, feasibility, induction of...

Researchers' work from University of Michigan focuses on cancer vaccines.
December 1, 2008... "Dendritic cell (DC)-based antitumor immunotherapy is a promising cancer therapy. We have previously shown that tumor-derived TGF-beta limits the efficacy of the DC/tumor fusion vaccine in mice," scientists writing in the Journal of Immunology...

Data on cancer vaccines described by researchers at Kyushu University, Medical Institute of Bioregulation.
December 1, 2008... Investigators publish new data in the report 'Potential role of dendritic cell vaccination with MAGE peptides in gastrointestinal carcinomas.' "Dendritic cells (DCs) loaded with tumor antigens have been emerging as a new strategy in cancer...

New findings in cancer vaccines described by S. Viviani and co-researchers.
December 1, 2008... New investigation results, '20 years into the Gambia Hepatitis Intervention Study: assessment of initial hypotheses and prospects for evaluation of protective effectiveness against liver cancer,' are detailed in a study published in Cancer...

Research by A. Sloots and colleagues in cancer vaccines provides new insights.
December 1, 2008... Fresh data on cancer are presented in the report 'DNA vaccines targeting tumor antigens to B7 molecules on antigen-presenting cells induce protective antitumor immunity and delay onset of HER-2/Neu-driven mammary carcinoma.' "Presentation of...

Researchers from Duke University, Division of Neurosurgery describe findings in glioblastoma vaccines.(Clinical report)
December 1, 2008... Current study results from the report, 'Detection of humoral response in patients with glioblastoma receiving EGFRvIII-KLH vaccines,' have been published. "The epidermal growth factor receptor variant III (EGFRvIII) is a consistent...

Mexican Department of Public Health to Launch Screening for Papillomavirus, Cause of Cervical Cancer.
December 1, 2008... In a campaign to significantly reduce the most common cancer affecting Mexican women, the Mexican Public Health Agency (Secretaria de Salud) announced that it is launching the first phase of a program that will offer free testing for human...

Pressure BioSciences, Inc. Reports Record Third Quarter 2008 Financial Results and Provides Business Update.(Financial report)
December 1, 2008... Pressure BioSciences, Inc. (NASDAQ:PBIO) ("PBI" and the "Company") announced that total revenue for the third quarter of 2008 was $265,662 compared to $138,052 for the comparable period in the prior year. Revenue from the sale of PCT products...

Of Mice and Men: Award-Winning Oncologist Leads New Advancement in Personalized Medicine.(Clinical report)
December 1, 2008... After hearing the words, "you've got cancer," most patients are given a drug or combination of agents according to guidelines or standards of care. These treatments, in the oncologist's best judgment, are considered most likely to work based...

Southern Research Names Andrew D. Penman Vice President of Drug Development.
December 1, 2008... Southern Research Institute announced that Andrew D. Penman, Ph.D., has been named vice president of its Drug Development Division. Dr. Penman will lead Southern Research's preclinical contract research operations in toxicology, bioanalytical...

Findings from T. Miyashita and co-researchers advance knowledge in cancer vaccines.
December 8, 2008... According to a study from the United States, " We developed and evaluated a GM-CSF whole-cell tumor vaccine for esophageal cancer. Experimental design Cell lines derived from surgically induced rat reflux esophageal tumors were passaged in...

Research from Peking University reveals new findings on cancer vaccines.(Report)
December 8, 2008... "Tumors may present antigens to T cells but lack costimulatory signals which are necessary to initialize an effective immunologic response. This study aimed to develop a tumor cell-based cancer vaccine by genetically modifying oral squamous...

Studies from W.J. Urba and co-authors have provided new information about cancer vaccines.
December 8, 2008... "This phase I-II study evaluated the safety, clinical activity and immunogenicity of an immunotherapy developed from human prostate cancer cell lines (PC-3 and LNCaP) modified to secrete granulocyte-macrophage colony-stimulating factor....

Study data from University of California update knowledge of kidney disease.
December 8, 2008... "Chronic kidney disease (CKD) and peripheral arterial disease (PAD) are common and frequently coexist. Among subjects with CKD, arterial disease may be due to atherosclerosis, medial arterial calcification (MAC), or both conditions...

Study findings on cancer vaccines are outlined in reports from University of Texas.(Report)
December 8, 2008... "Sezary syndrome (SzS), the leukemic variant of cutaneous T-cell lymphomas, is incurable. Dendritic cells (DCs) transfected with tumor mRNA can stimulate antitumor immunity in certain cancer patients," scientists writing in the Journal of...

Research on cancer vaccines described by R.M. Rogoza and colleagues.
December 8, 2008... Current study results from the report, 'Optimization of primary and secondary cervical cancer prevention strategies in an era of cervical cancer vaccination: a multi-regional health economic analysis,' have been published. "With the recent...

Recent findings from China Medical University highlight research in cancer vaccines genetics.(Report)
December 8, 2008... A report, 'Glypican3 in genetically modified human monocyte-derived dendritic cells induced specific cytotoxity against glypican3 overexpressing human hepatocellular carcinoma cells in vitro,' is newly published data in Saudi Medical Journal....

Researchers from Ecole normale superieure detail findings in gene therapy.
December 8, 2008... A new study, 'Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice,' is now available. According to a study from Cachan, France, "TSAP6 (tumor...

Investigators at Leiden University have published new data on immunization.
December 8, 2008... Data detailed in 'Surgery followed by persistence of high-grade squamous intraepithelial lesions is associated with the induction of a dysfunctional HPV16-specific T-cell response' have been presented. In this recent article published in the...

MICROFLUIDICS INTRODUCES WIDE RANGE OF MICROFLUIDIZER[R] PROCESSORS FOR PHARMACEUTICAL AND BIOTECHNOLOGY INDUSTRIES Aseptic, Enhanced, and Basic Models Meet Industry-Specific Needs.
December 8, 2008... Aseptic, Enhanced, and Basic Models Meet Industry-Specific Needs Microfluidics has introduced a new line of Microfluidizer[R] high-shear fluid processors designed specifically for the pharmaceutical and biotechnology industries. The...

Researchers from University of Washington detail findings in cancer vaccines.
December 15, 2008... "Breast cancer is immunogenic and well suited to treatment via immunomodulation. The disease is often treated to remission and time to relapse is generally measured in years in many cases," scientists in the United States report (see also...

Research on DNA vaccines reported by scientists at Seoul National University.
December 15, 2008... According to a study from Seoul, South Korea, "Her-2/neu is a well-characterized tumor-associated antigen, the overexpression of which in human carcinomas correlates with a poor prognosis. Here, we evaluated Her-2/neu-specific humoral and...

Research from E.H. Elbasha and co-researchers provides new data on human papillomavirus.
December 15, 2008... "A prophylactic quadrivalent (types 6/11/16/18) vaccine against oncogenic and warts-causing genital Human papillomavirus (HPV) types was approved by the US Food and Drug Administration in 2006. This paper presents a nonlinear, deterministic,...

Research reports from University of California provide new insights into behavior research.
December 15, 2008... "Work-family spillover research focuses on how negative and positive moods in one life domain carry over to another. Domain-specific etiologies (e.g., family conflict) are often emphasized to explain spillover," investigators in the United...

Blood Tests Can Help Detect Presence of Necrotizing Soft Tissue Infections.
December 15, 2008... With less than half of patients with necrotizing soft tissue infections displaying the physical signs of these very serious infections, researchers have found two simple blood tests can help physicians diagnose what is commonly known as...

Reports by S. Negoita and co-researchers describe recent advances in cancer vaccines.(Report)
December 15, 2008... New research, 'Distribution of treatment for human papillomavirus-associated gynecologic carcinomas before prophylactic vaccine,' is the subject of a report. According to recent research from the United States, "This report describes the...

Research by G. Copeland and colleagues in cancer vaccines provides new insights.
December 15, 2008... Fresh data on cancer are presented in the report 'Total burden and incidence of in situ and invasive cervical carcinoma in Michigan, 1985-2003.' "With the recent licensure of a vaccine that protects against human papillomavirus (HPV) types 16...

Research on cancer vaccines detailed by scientists at Centers for Disease Control and Prevention.
December 15, 2008... Data detailed in 'Preventing cervical cancer : overviews of the National Breast and Cervical Cancer Early Detection Program and 2 US immunization programs' have been presented. "Three federal programs with the potential to reduce cervical...

Researchers from Centers for Disease Control and Prevention describe findings in cancer vaccines.(Report)
December 15, 2008... Current study results from the report, 'Incidence of in situ and invasive vulvar cancer in the US, 1998-2003,' have been published. "The human papillomavirus (HPV) vaccine has been shown to prevent precancerous lesions of the vulva with the...

Researchers from Johns Hopkins Medical Institutions, Department of Pathology report on findings in cancer vaccines.
December 15, 2008... Researchers detail in 'alpha-Galactosylceramide enhances the protective and therapeutic effects of tumor cell based vaccines for ovarian tumors,' new data in cancer. "Ovarian cancer is one of the leading causes of death from gynecological...

Researchers from Royal Women's Hospital detail findings in cancer vaccines.
December 15, 2008... A new study, 'The need for public education on HPV and cervical cancer prevention in Asia. Opinions of experts at the AOGIN conference,' is now available. According to a study from Carlton, Australia, "Asia accounts for more than half of all...

Scientists at Centers for Disease Control and Prevention detail research in cancer vaccines.
December 15, 2008... Researchers detail in 'Cancer registries and monitoring the impact of prophylactic human papillomavirus vaccines: the potential role,' new data in cancer. According to recent research from the United States, "The recent US Food and Drug...

Scientists at Kimmel Cancer Center report research in cancer vaccines.
December 15, 2008... A new study, 'HPV prophylactic vaccines and the potential prevention of noncervical cancers in both men and women,' is now available. "Human papillomavirus (HPV) is a necessary cause of cervical cancer. In addition, on the basis of the...

Studies by A. Balamurugan and co-authors describe new findings in cancer vaccines.
December 15, 2008... Investigators publish new data in the report 'Potential role of human papillomavirus in the development of subsequent primary in situ and invasive cancers among cervical cancer survivors.' "The recent licensure of human papillomavirus (HPV)...

Research on cancer vaccines epidemiology reported by scientists at National Center for Chronic Disease Prevention and Health Promotion.
December 15, 2008... Current study results from the report, 'Understanding the burden of human papillomavirus-associated anal cancers in the US,' have been published. According to recent research published in the journal Cancer, "Anal cancer is an uncommon...

Researchers from Centers for Disease Control and Prevention publish findings in cancer vaccines prevention.
December 15, 2008... Scientists discuss in 'Burden of cervical cancer in the United States, 1998-2003' new findings in cancer vaccines. According to recent research from the United States, "Recent interest in human papillomavirus (HPV)-associated cancers and the...

Scientists at Centers for Disease Control and Prevention describe research in human papillomavirus vaccines.(Report)
December 15, 2008... Research findings, 'A review of prophylactic human papillomavirus vaccines: recommendations and monitoring in the US,' are discussed in a new report. "It has been estimated that genital human papillomavirus (HPV) is the most common sexually...

RNCOS Releases a New Report- Global Cancer Treatment Forecast to 2012.
December 15, 2008... RNCOS has recently added a new Market Research Report titled, "Global Cancer Treatment Forecast to 2012" to its report gallery. This report is a comprehensive study on the global cancer market and gives statistics and analysis on cancer...

The Leukemia & Lymphoma Society and Memgen Announce New Chronic Lymphocytic Leukemia Clinical Trial.
December 15, 2008... The Leukemia & Lymphoma Society (LLS) and Memgen, LLC jointly announce the beginning of a new clinical trial of ISF35, a cancer vaccine, at the University of California, San Diego (UCSD) (see also Cancer Vaccines). LLS is collaborating on...

Updated Pictures of CEL-SCI Manufacturing Facility Available Online.
December 15, 2008... In response to numerous shareholder inquiries, CEL-SCI Corporation (NYSE Alternext US: CVM) announced that it has added updated pictures of it new manufacturing facility to its website. The pictures can be accessed through CEL-SCI's homepage...

Vical Receives Milestone Payment from Merck & Co., Inc. Triggered by Planned Initiation of Investigational Cancer DNA Vaccine Trial.
December 15, 2008... Vical Incorporated (NASDAQ: VICL) announced the receipt of a $1.0 million milestone payment from Merck & Co., Inc. based on Merck's planned initiation of a Phase I clinical trial of an investigational plasmid DNA (pDNA) cancer vaccine. The...

Data from Osaka University, Medical Department provide new insights into cancer vaccines.
December 22, 2008... According to a study from Suita, Japan, "The Wilms' tumor gene WT1 is overexpressed in various kinds of hematopoietic malignancies as well as solid cancers, and this protein has been demonstrated to be an attractive target antigen for cancer...

Studies from Wayne State University update current data on cancer vaccines.
December 22, 2008... According to recent research from the United States, "5'-N-Phenylacetyl sTn (sTnNPhAc), an unnatural derivative of sTn antigen expressed by many tumors, and its alpha-linked protein conjugates were prepared and investigated to explore...

Study results from P. Chiarella et al provide new insights into DNA vaccines.(Report)
December 22, 2008... According to recent research from Rome, Italy, "Plasmid DNA vaccination combined with electroporation (EP) provides a promising approach for the prevention of infectious diseases and for cancer immunotherapy. This technology has been described...

Reports outline immunotherapy study findings from Curtin University of Technology.
December 22, 2008... "Anti-cancer immunotherapies aim to generate resolution of all existing tumors, including inaccessible ones, and provide long-term protection against recurrence. This is rarely achieved," scientists writing in the journal International...

University of California publishes research in salmonellosis.
December 22, 2008... According to a study from the United States, "Immunity conferred by conventional vaccines is restricted to a narrow range of closely related strains, highlighting the unmet medical need for the development of vaccines that elicit protection...

Leading U.S. Cancer Organizations Unite Against the Growing Global Cancer Burden.
December 22, 2008... Despite the recent good news that cancer incidence and death rates for men and women in the United States continue to decline, cancer is projected to become the leading cause of death worldwide in the year 2010, and low- and middle-income...

Protection from the own immune system.
December 29, 2008... Some 80,000 people in Germany suffer from multiple sclerosis u their immune system attacks and destroys healthy nerve tissue. Researchers at the Heidelberg University Hospital and the German Cancer Research Center in Heidelberg have succeeded...

Scientists at University of Berlin release new data on cancer vaccines.
December 29, 2008... " Metastatic disease is a major cause of mortality in colorectal cancer patients. Even after complete resection of isolated liver metastases, recurrence develops in the majority of patients," researchers in Berlin, Germany report (see also...

Study data from C. Dulsat and co-authors update knowledge of cancer vaccines.
December 29, 2008... "Non-small cell lung cancer (NSCLC) accounts for approximately 75% of all lung cancers, the leading cause of cancer-related deaths in both men and women worldwide. Advances in vaccine therapy strategies, designed to stimulate an immune response...

Patients with early Parkinsons disease experienced better symptom control and improvements in daily activities with Stalevo[R] than carbidopa/levodopa, according to study.
December 29, 2008... Study results published online in Movement Disorders showed that Stalevo(R) (carbidopa, levodopa and entacapone) provides better symptom control and greater improvements in activities of daily living for people with early Parkinson's disease...

Data from P. Lenzi and colleagues advance knowledge in human papillomavirus.(Report)
December 29, 2008... According to recent research published in the journal Transgenic Research, "Human Papillomavirus (HPV) is the causal agent of cervical cancer, one of the most common causes of death for women. The major capsid L1 protein self-assembles in Virus...

Study results from University of Michigan broaden understanding of human papillomavirus.
December 29, 2008... According to recent research from the United States, "Human papillomavirus (HPV) disease and vaccines and several controversial issues associated with vaccine administration are reviewed. HPV infection is the most common sexually transmitted...

New immunotherapy study findings have been reported from Radboud University.
December 29, 2008... According to recent research from Netherlands, "The occurrence of vitiligo in patients with melanoma is especially reported for patients undergoing immunotherapy. While vitiligo in these patients is thought to be related to an immune response...

Data on cancer vaccines described by researchers at New York University, Cancer Institute.
December 29, 2008... Investigators publish new data in the report 'KBMA Listeria monocytogenes is an effective vector for DC-mediated induction of antitumor immunity.' "Vaccine strategies that utilize human DCs to enhance antitumor immunity have yet to realize...

Data on cancer vaccines published by researchers at University of Nijmegen.(Survey)
December 29, 2008... Data detailed in 'Young adults and acceptance of the human papillomavirus vaccine' have been presented. In this recent report published in the journal Public Health, researchers in Netherlands conducted a study "To determine whether young Dutch...

Data on cancer vaccines reported by researchers at Merck & Company, Inc.
December 29, 2008... Fresh data on cancer are presented in the report 'Prophylactic HPV vaccines: new interventions for cancer control.' "Human Papillomavirus (HPV) infection causes cervical cancer, a significant portion of anal, vulvar, vaginal, and oropharyngeal...

Scientists at Fujian Medical University, Department of Hematology discuss research in gene therapy.
December 29, 2008... New investigation results, 'In vitro inducing effect of dendritic cells cotransfected with survivin and granulocyte-macrophage colony-stimulating factor on cytotoxic T cell to kill leukemic cells,' are detailed in a study published in Chinese...

New immunization study findings reported from University of Milan, Department of Public Health.
December 29, 2008... Fresh data on immunization are presented in the report 'The global impact of vaccination against hepatitis B: a historical overview.' According to recent research published in the journal Vaccine, "Hepatitis B virus (HBV) infection is a world...

MabVax Therapeutics Receives Two Small Business Technology Transfer Program Awards From the National Cancer Institute.
December 29, 2008... MabVax Therapeutics Inc., a privately held immunotherapeutics discovery and development company focused on the development and commercialization of novel immunotherapies for the treatment of cancer, announced the company has received two grant...

Merck KGaA acquires manufacturing rights for Stimuvax from Oncothyreon.
December 29, 2008... Oncothyreon Inc. (NASDAQ:ONTY) (TSX:ONY) announced that Merck KGaA of Darmstadt, Germany has licensed the right to manufacture Stimuvax(R) and, through its affiliate EMD Serono Canada Inc., purchased current inventory and certain assets...

Ireland Cancer Center researcher finds most triple-negative breast cancers express muc-1 target.
December 29, 2008... Research out of the Ireland Cancer Center of University Hospitals Case Medical Center has found that the vast majority of triple negative breast cancers express the MUC-1 target. This first-of-its-kind finding, presented today at the San...

Life Sciences Discovery Fund Awards $4.7 Million to Support New Vaccine Program.
December 29, 2008... The Washington Life Sciences Discovery Fund (LSDF) has awarded nearly $4.7 million to launch the start-up phase of the Washington Vaccine Alliance (WAVA) and to support initial research into three new vaccines for E. coli, herpes and syphilis....