Cancer Vaccine Week articles from December 2004

Cancer Vaccine Week archives from December 2004

Dendritic cells boost antitumor activity of adoptively transferred T cells.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Dendritic cells strongly boost the antitumor activity of adoptively transferred T cells in vivo. According to published research from the United States, "Dendritic cells (DCs) have been well...

Expression of the cell surface mucin gene family in adenocarcinomas reported.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Scientists report the expression of the cell surface mucin gene family in adenocarcinomas in a recent issue of the International Journal of Oncology. According to recent research from Australia,...

Tumor vaccine therapy reviewed.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Researchers review tumor vaccine therapy in a recent issue of Blood. According to published research from the United States, "Fusion proteins containing chemokine receptor ligands have been used to...

Leukemic cells have high B7-H1 and B7.1 expression and resist lysis.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- In a model of tumor dormancy, long-term persistent leukemic cells have increased B7-H1 and B7.1 expression and resist CTL-mediated lysis. According to a study from France, "In tumor dormancy, tumor...

Quiescent phenotype of tumor-specific CD8+ T cells following immunization.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Researchers report a quiescent phenotype of tumor-specific CD8+ T cells following immunization in a recent issue of the journal Blood. "In a human melanoma model of tumor antigen (TA)-based...

Intratumoral CCL5 overexpression delays tumor growth.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Intratumoral CCL5 overexpression delays tumor growth. According to recent research from France, "Chemokines participate in the antitumor immune response by regulating the movement and positioning...

Type-1 innate and acquired immunity play crucial roles in tumor immunotherapy.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Type-1 innate and acquired immunity play crucial roles in tumor immunotherapy. According to a study from Japan, "the discovery of a large array of tumor antigens has demonstrated that host...

Elizabeth Edwards's diagnosis encourages others to get check-ups.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Elizabeth Edwards said she is glad her breast cancer diagnosis is encouraging people to stop neglecting their own health, as she admits she did. "I didn't test myself as often," and didn't get...

Endogenous BRCA1-IRIS may influence DNA replication initiation machinery.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Endogenous BRCA1-IRIS may positively influence the DNA replication initiation machinery. According to published research from the United States, "Breast cancer is the most common malignancy among...

Patients receiving taxane-based chemotherapy not at higher risk of pneumonitis.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Researchers at The University of Texas M.D. Anderson Cancer Center have shown that breast cancer patients treated with taxane-based chemotherapies and radiation are not at increased risk of developing...

Phage display library from lymph nodes of breast cancer patients constructed.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Researchers have constructed phage display libraries from reactive lymph nodes of breast carcinoma patients. According to a study from Germany, "The display of recombinant antibody fragments on the...

Biopharma reports third quarter 2004 results, clinical achievements.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Progenics Pharmaceuticals, Inc., (NASDAQ: PGNX) announced its results of operations for the third quarter ended September 30, 2004, and for the first 9 months of 2004. Revenues for the third...

Biopharmaceuticals company announces third quarter results, progress made.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Keryx Biopharmaceuticals announced its financial results for the third quarter ended Sept. 30, 2004. At Sept. 30, 2004, Keryx announced cash, cash equivalents, interest receivable and investment...

Biotech company announces restructured agreement for cancer drug.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Ligand Pharmaceuticals announced that it has restructured its agreement with Eli Lilly and Company with respect to the royalties payable to Lilly on sales of Ligand's marketed cancer drug Ontak...

Biotech establishes new business units for pain and oncology.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Ligand Pharmaceuticals announced that it has established separate therapeutically focused business units for its pain and oncology products. Patrick M. Shea, formerly vice president of marketing,...

Molecular diagnostics company announces expansion of diagnostic pipeline.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Third Wave Technologies Inc. (TWTI) provided new details about the expansion of the company's molecular diagnostic pipeline and issued preliminary guidance for 2005 clinical molecular diagnostic...

New company to develop, produce patient-specific cancer vaccines.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Baylor Health Care System announced its formation of a cancer immunotherapy company, known as ODC Therapy, Inc. ODC will develop, produce and distribute customized cancer vaccines, including a...

Clinical studies needed to evaluate role of BRCA1 in chemotherapy response.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Prospective clinical studies are needed to evaluate the role of BRCA1 in response to taxane-based chemotherapy, researchers say. Loss of BRCA1 function is associated with sensitivity to...

Fused cell vaccination and CpG oligodeoxynucleotides reject tumor recurrence.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Fused cell vaccination and CpG oligodeoxynucleotides reject tumor recurrence. "Immunization with dendritic cells (DCs) using various antigen (Ag)-loading approaches has shown promising results in...

Program to implement required Pap interpretation proficiency testing announced.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Women will soon begin to have added assurance that the medical professionals who read their Pap tests are qualified to do so. The "added assurance" will be provided by a nationwide proficiency test...

European cancer organization offers guidelines for treating anemia.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- New European Organization for Research and Treatment of Cancer (EORTC) guidelines aim to assist physicians in managing anemia more effectively in their patients with cancer by providing advice on the...

Listeria-based cancer vaccines segregate immunogenicity from toxicity.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Listeria-based cancer vaccines segregate immunogenicity from toxicity. According to a study from the United States, "The facultative intracellular bacterium Listeria monocytogenes is being developed...

IL-13 antagonist and Pseudomonas toxin fusion protein is anticancer.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- An interleukin-13 receptor-targeted cytotoxin composed of IL-13 antagonist and Pseudomonas exotoxin exhibited antitumor activity. According to a study from the United States, "We have shown...

Interleukin-15 transfection plus CD8+ T cells cause colon cancer rejection.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Interleukin-15 transfection plus CD8+ T cells cause colon cancer rejection. "Although interleukin (IL)-15 augments innate and acquired immunities, IL-15 expression is controlled at the levels of...

Primary endpoint achieved in phase 3 trial of genasense plus chemotherapy.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Genta Incorporated (NASDAQ:GNTA) announced that the company's randomized phase 3 clinical trial of Genasense (oblimersen sodium) Injection in patients with relapsed or refractory chronic lymphocytic...

Affitech, Peregrine expand collaboration to develop new fully human antibodies.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- [lw2][pb2][uw2][vw2] (carol for Heather) Peregrine Pharmaceuticals Julie Marshall, +1-800-987-8256 Peregrine Pharmaceuticals, Inc., (NASDAQ:PPHM) and Affitech AS recently announced that they have...

Anti-cancer vaccine R&D agreement signed.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- IDM (Immuno-Designed Molecules) announced the signing of a research and development agreement with the Walter Reed Army Institute of Research involving the development of an anti-cancer vaccine...

Biopharma, consortium collaborate to treat brain cancer patients.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- [qw2][uw2][bb2][pb2] (carol for Heather) Peregrine Pharmaceuticals Julie Marshall, +1-800-987-8256, or info@hawkassociates.com Peregrine Pharmaceuticals, Inc., (NASDAQ:PPHM) has entered into a...

Companies combine technologies to search for cancer-fighting compounds.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Tripos, Inc. (TRPS), and NovaScreen Biosciences Corporation have announced a collaboration to provide a drug discovery solution to Strida Pharma Inc. for its cancer therapeutics development program...

Companies introduce solid support product for manufacture of oligonucleotides.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Nitto Denko Corporation, a polymer company, and Isis Pharmaceuticals, Inc. (ISIS), a RNA-based drug discovery and development company, have jointly developed a new solid support for the manufacture of...

DNA vaccines induce epitope-specific CTLs against histocompatibility antigens.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- DNA fusion vaccines induce targeted epitope-specific CTLs against minor histocompatibility antigens from a normal or tolerized repertoire. According to a study from England, "We have designed DNA...

Indian pharmaceutical company launches new cancer diagnostic product.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Indian pharmaceutical company J.B. Chemicals & Pharmaceuticals launched a high-tech diagnostic product used for angiographies, neurological diseases and diagnosis of cancer patients. The company...

Cervical cancer's image as a niche market hinders drug development.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Decision Resources, Inc., has found that, because of slow-to-change treatment strategies and a low burden of disease in developed countries, interest in trials of novel agents for invasive cervical...

Novartis picks drug for development from protein kinase research collaboration.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Vertex Pharmaceuticals Incorporated (VRTX) announced that Novartis has selected a small molecule protein kinase inhibitor, VX-322, from Vertex for clinical development for the treatment of cancer. ...

MyVax maker announces Q3 net loss of $6.7 million.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Genitope Corp. (GTOP) announced financial results for the third quarter and 9 months ended September 30, 2004. For the third quarter of 2004, Genitope Corp. reported a net loss of $6.7 million, or...

Pharmaceutical company reports third quarter revenue increase of 58%.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Ligand Pharmaceuticals reported record net product sales for the third quarter ended Sept. 30, 2004, of $44.7 million, compared to $28.1 million the third quarter of 2003, an increase of 59% driven by...

IM and gastric adenocarcinoma may share the same genetic alterations.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- IM and gastric adenocarcinoma may share the same genetic alterations. "Gastric carcinogenesis is attributable to interacting environmental and genetic factors, through a sequence of events...

Inflammatory responses in cervical neoplasia suppressed in HIV-positive women.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Inflammatory responses in cervical intraepithelial neoplasia are suppressed in HIV-positive women. "The role of mucosal immunity in human papillomavirus (HPV)-related cervical diseases is poorly...

Methods of identifying new antigenic epitopes of HPV 16 developed.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Scientists have developed new methods of identifying new antigenic epitopes of human papillomavirus type 16 E6 and E7 proteins. "Human papillomavirus (HPV) infection is the most common cause of...

Prevalence of HPV infection differs for men and women.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- The age-specific prevalence of sexually transmitted human papillomavirus infection in women differs substantially from that in men who have sex with men, according to a new study. The study was led...

Dendritic cell-based vaccines effective against HPV-associated tumors.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Dendritic cell-based vaccines were effective against HPV-associated tumors after surgical reduction. According to recent research from the Czech Republic, "Dendritic cell (DC)-based vaccines are...

Heat shock protein suicide gene-based tumor vaccine provokes antitumor activity.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Heat shock protein suicide gene-based tumor vaccine provokes antitumor activity. According to a study from the United States, "tumor cells harbor a repertoire of unique, mutated antigens and shared...

Drug Web sites foster doctor and patient loyalty.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- According to a new survey of pharmaceutical companies with drug Web sites, doctors and patients are increasingly turning to the Internet for information on diseases such as cancer. Best Practices...

Cancer vaccine helped patients in phase IIb trial survive 4.4 months longer.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Biomira, Inc., (BIOM, BRA) and Merck KGaA reiterated that data from the companies' phase IIb BLP 25 Liposome vaccine (L-BLP25) trial in patients with Stage IIIb and IV non-small cell lung cancer (NSCLC)...

South Florida cancer center seeks students for summer intern program.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- The H. Lee Moffitt Cancer Center & Research Institute is accepting applications for its Summer Program for the Advancement of Research Knowledge (SPARK). High school graduates and college undergraduates...

Data updates from phase 2 trial for metastatic melanoma drug presented.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Vical Incorporated (VICL) reported safety and efficacy data from its high-dose phase 2 trial of Allovectin-7 in patients with metastatic melanoma, updating interim data reported in June 2004. ...

Aged mice develop protective antitumor immune responses with costimulation.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Aged mice develop protective antitumor immune responses with appropriate costimulation. According to a study from the United States, "There is a clear decrease in CD8+ T cell effector function with...

$10 million grant to evaluate lifestyle changes on breast cancer patients.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Researchers at Kaiser Permanente announced the receipt of a $10 million grant to study whether lifestyle factors, such as diet, exercise and use of complementary and alternative medicine (CAM), impact...

Combined chemotherapy and immunotherapy generates tumor rejection.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Combined chemotherapy and immunotherapy generates tumor rejection. According to published research from the Czech Republic, "Human papilloma virus 16 (HPV16) E6/E7 transformed mouse kidney cells...

Pharmaceutical company announces Phase I clinical trial for myeloma treatment.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Kosan Biosciences announced that it has initiated a company-sponsored Phase Ib clinical trial to investigate KOS-953, Kosan's formulation of 17-AAG in combination with bortezomib (Velcade), a recently...

Plasma from pregnant rats has antitumoral activity.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Scientists in Spain have found that plasma from pregnant rats exhibits antitumoral activity. N. Carbo, University of Barcelona, and colleagues reported, "Plasma from 12-day pregnant rats showed a...

Focal adhesion kinase may be important therapeutic target.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Focal adhesion kinase may be important therapeutic target in ovarian cancer, M.D. Anderson Cancer Center gynecologic oncologists say. According to A.K. Sood and colleagues, "Focal adhesion kinase...

Gene expression profiling aids in ovarian cancer prognosis.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- The identification of a gene expression profile using microarray technology may help clinicians better determine the prognosis of patients with advanced stage ovarian cancer and may eventually help...

Hypermethylation is a common, relatively early event in ovarian tumorigenesis.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Oncologists with the Fox Chase Cancer Center, Philadelphia, have determined that hypermethylation is a common, relatively early event in ovarian tumorigenesis that can be detected in serum DNA of...

Anticancer drug receives Candian patent.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Lorus Therapeutics announced that its wholly owned subsidiary, GeneSense Technologies Inc., has been allowed a patent by the Canadian Patent Office entitled "Antitumor Antisense Sequences Directed...

Oncology-focused pharmaceutical names new heads of biologics, regulatory affairs.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Spectrum Pharmaceuticals, Inc. (SPPI) has appointed Kolli Prasad, PhD, the former head of R&D for Shantha Biotechnics Pvt. Ltd., director of R&D, biologics. The company also appointed Paul Vilk,...

Despite setbacks, strong growth seen in $7 billion vaccine market.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- The worldwide market for preventive vaccines will total nearly $7 billion in 2004 despite the widely reported supply interruptions of flu vaccine in the United States, according to a new study from...

Dendritic cell-tumor fusion vaccines being developed for renal cell carcinoma.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Dendritic cell-tumor fusion vaccines are being developed for renal cell carcinoma. "Renal cell carcinoma is a malignant disease that demonstrates resistance to standard chemotherapeutic agents. A...

Allogeneic stem-cell transplantation for renal-cell cancer reviewed.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Researchers review allogeneic stem-cell transplantation for renal-cell cancer in a recent issue of Lancet Oncology. "Metastatic renal-cell carcinoma (RCC) is resistant to chemotherapy, and patients...

Delta yej Salmonella mutants induce superior CD8+ T-cell responses.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Scientists have identified Salmonella typhimurium genes responsible for interfering with peptide presentation on MHC class I molecules. According to recent research published in the journal Cellular...

TP53 mutations detected in squamous-cell carcinomas of conjunctiva.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- TP53 mutations were detected in squamous-cell carcinomas of the conjunctiva. "Squamous cell carcinoma of the conjunctiva is associated with sun exposure and often occurs in HIV-positive individuals....

HER-2 Protein AutoVac starts phase II trial in breast cancer.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Pharmexa will now initiate the first phase II trial with the HER-2 Protein AutoVac breast cancer vaccine. The trial that includes up to 50 breast cancer patients will start in Hungary and is...

Vaccinia vector with antigen-linked calreticulin elicits an antitumor response.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Vaccinia vector with antigen-linked calreticulin elicits an antitumor response. According to a study from the United States, "vaccinia vaccines have become important vectors for antigen-specific...

Porcine adenoviral vectors are effective vehicles for gene delivery.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Porcine adenoviral vectors are effective vehicles for gene delivery. According to recent research from the United States, "preexisting immunity against human adenoviruses (HAd) limits the...

Wilms' tumor gene peptide vaccine causes cancer regression.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- A Wilms' tumor gene peptide vaccine induced Wilms' tumor gene-specific cytotoxic T lymphocytes and caused cancer regression. "The Wilms' tumor gene WT1 is overexpressed in leukemias and various...

Antibody response improved after antigen-pulsed dendritic cell vaccine.
December 13, 2004... 2004 DEC 13 - (NewsRx.com & NewsRx.net) -- The antibody response after vaccination with antigen-pulsed dendritic cells can be improved. "Dendritic cells (DCs) are the most potent antigen-presenting cells of the immune system capable of...

Manipulating dendritic cell biology provides active immunotherapy of cancer.
December 13, 2004... 2004 DEC 13 - (NewsRx.com & NewsRx.net) -- Manipulating dendritic cell biology provides active immunotherapy of cancer. According to a study from the United States, "Dendritic cells (DCs) are specialized antigen-presenting cells (APCs) that...

Mono-epitopic peptide-based vaccine induces regression of liver tumor.
December 13, 2004... 2004 DEC 13 - (NewsRx.com & NewsRx.net) -- Mono-epitopic peptide-based immunotherapy induced regression of an established liver tumor. According to recent research published in the Journal of Immunology, "Most types of cancer are difficult...

IFN-gamma enables cross-presentation of protein antigen in Langerhans cells.
December 13, 2004... 2004 DEC 13 - (NewsRx.com & NewsRx.net) -- IFN-gamma enables cross-presentation of exogenous protein antigen in human Langerhans cells by potentiating maturation. According to a study from the United States, "We compared monocyte-derived...

Protein to antigen fusion heightens the efficacy of DNA cancer vaccine.
December 13, 2004... 2004 DEC 13 - (NewsRx.com & NewsRx.net) -- Protein to antigen fusion heightens the efficacy of DNA cancer vaccine. "Delivery of antigens by injection of the encoding DNA allows access to multiple antigen-presenting pathways. Knowledge of...

Study finds chemical attraction makes HER2-positive breast cancer invade organs.
December 13, 2004... 2004 DEC 13 - (NewsRx.com & NewsRx.net) -- Researchers at the University of Texas M.D. Anderson Cancer Center have solved the mystery of why an aggressive form of HER2-positive breast cancer travels readily to a few key organs-lungs, liver and...

'Handcuffing' and unpairing controls of P1 plasmid replication.
December 13, 2004... 2004 DEC 13 - (NewsRx.com & NewsRx.net) -- Researchers from the National Cancer Institute in the United States have shown that the a phenomena called 'handcuffing' and unpairing are important in controlling the replication of plasmid P1. ...

Enzon, partner announce the filing of a new drug submission to Health Canada.
December 13, 2004... 2004 DEC 13 - (NewsRx.com & NewsRx.net) -- Enzon Pharmaceuticals, Inc. (ENZN) and Inex Pharmaceuticals Corp. (IEX) (INEX) announced that they have filed a new drug submission (NDS) with the Therapeutics Products directorate of Health Canada for...

U.S. FDA grants fast track status to glufosfamide for treating pancreatic cancer.
December 13, 2004... 2004 DEC 13 - (NewsRx.com & NewsRx.net) -- Threshold Pharmaceuticals Inc. announced that the U.S. Food and Drug Administration (FDA) has granted fast track status to one of the company's drug candidates, glufosfamide, for injection, to treat...

Unique antigens for therapeutic cancer vaccines reviewed.
December 13, 2004... 2004 DEC 13 - (NewsRx.com & NewsRx.net) -- A researcher reviews unique antigens for therapeutic cancer vaccines in a recent issue of the Proceedings of the National Academy of Sciences of the United States of America. According to a study...

Biotech company and university team up to develop therapeutics for unstable plaque.
December 13, 2004... 2004 DEC 13 - (NewsRx.com & NewsRx.net) -- Cancer and cardiovascular biotech company Kereos said that it has extended its research partnership with Washington University in St. Louis to continue ongoing development of unique therapeutics that...

Alliance formed to develop melanoma product MDX-010.
December 13, 2004... 2004 DEC 13 - (NewsRx.com & NewsRx.net) -- Bristol-Myers Squibb Company (BMY) and Medarex, Inc., (MEDX) announced a worldwide collaboration to develop and commercialize MDX-010, a fully human antibody investigational product targeting the...

G-CSF response before leukopenia predicts infection defense in HD chemotherapy.
December 13, 2004... 2004 DEC 13 - (NewsRx.com & NewsRx.net) -- G-CSF response before leukopenia predicts infection defense in high dose chemotherapy. According to recent research from Germany, "An active assessment of the host capacity to prevent infection...

Pharmaceutical company announces new research collaboration.
December 13, 2004... 2004 DEC 13 - (NewsRx.com & NewsRx.net) -- Locus Pharmaceuticals, Inc., announced the initiation of a multi-stage research collaboration with Dow AgroSciences LLC, a subsidiary of The Dow Chemical Company, focused on agrochemicals and...

Cancer vaccine maker files shelf registration statement.
December 13, 2004... 2004 DEC 13 - (NewsRx.com & NewsRx.net) -- CancerVax Corporation (CNVX) announced that it has filed with the U.S. Securities and Exchange Commission a shelf registration statement on Form S-3, which, when declared effective, will permit...

Cancer-focused company announces direct equity issuance.
December 13, 2004... 2004 DEC 13 - (NewsRx.com & NewsRx.net) -- Geron Corp. (GERN) announced that it has entered into a definitive agreement to sell approximately 6.5 million shares of Geron common stock to institutional investors at $6.10 per share, for gross...

Epitope-focused company reports Q3 revenues of $2.1 million.
December 13, 2004... 2004 DEC 13 - (NewsRx.com & NewsRx.net) -- Epimmune, Inc., (EPMN) announced its financial results for the quarter and 9 months ended September 30, 2004. During the quarter, cash and cash equivalents declined by $1.2 million to an ending...

Genomics-focused company reports Q3 losses.
December 13, 2004... 2004 DEC 13 - (NewsRx.com & NewsRx.net) -- Genaera Corp. (GENR) announced its financial results for the 3 and 9 months ended September 30, 2004. Net loss applicable to common shareholders for the 3 months ended September 30, 2004 was...

HPV-like particles encapsidating IL-2 adjuvant enhanced immunogenicity.
December 13, 2004... 2004 DEC 13 - (NewsRx.com & NewsRx.net) -- Human papillomavirus (HPV)-like particles encapsidating interleukin-2 gene adjuvant enhanced mucosal and systemic immunogenicity. According to a study from South Korea, "Here, we report the...