Cancer Vaccine Week articles from April 2009

Cancer Vaccine Week archives from April 2009

Human papillomavirus genotype distribution in New Mexico cervical cancers.
April 6, 2009... DNA from human papilloma virus type 16 (HPV16) and HPV type 18 (HPV18) were found in the majority of invasive cervical cancers in New Mexico in the 1980s and 1990s, according to a population-based study published in the March 24 online issue of...

Data on cancer vaccines discussed by R. Fontana and colleagues.
April 6, 2009... "Dendritic cell (DC) targeting in vivo has recently been shown to confer strong and protective cytotoxic T lymphocyte (CTL) based immunity in tumor murine models. Our group has recently demonstrated in preclinical models that the infusion of...

Data on cancer vaccines published by researchers at Medical University of South Carolina.
April 6, 2009... According to a study from the United States, "Experimental results from studies with inbred mice and their syngeneic tumors indicated that the inoculation of semi-allogeneic cell hybrids (derived from the fusion between syngeneic tumor cells...

Reports from L. Mariani and co-researchers add new data to research in cancer vaccines.
April 6, 2009... According to recent research published in the Journal of Experimental & Clinical Cancer Research, "HPV vaccine is an exciting promise of the preventive medicine." "Although HPV-immunization programs still reveal a number of unanswered...

Study data from Columbia University provide new insights into cancer vaccines.
April 6, 2009... According to recent research from the United States, "Interleukin- 2 (IL-2) induces durable objective responses in a small cohort of patients with metastatic renal cell carcinoma (RCC) but the antigen(s) responsible for tumor rejection are not...

Findings in immunization reported from Z. Urry and co-researchers.
April 6, 2009... According to recent research from London, the United Kingdom, "Signaling through the TLR family of molecular pattern recognition receptors has been implicated in the induction of innate and adaptive immune responses. A role for TLR signaling in...

Research on life sciences detailed by C. Fonseca and co-authors.
April 6, 2009... "The identification of cancer antigens that contribute to transformation and are linked with immune-mediated tumor destruction is an important goal for immunotherapy. Toward this end, we screened a murine renal cell carcinomac DNA expression...

Researchers from Johns Hopkins University report on findings in cancer vaccines.
April 6, 2009... Researchers detail in 'Comparing care for breast cancer survivors to non-cancer controls: a five-year longitudinal study,' new data in cancer. "Deficiencies in care for cancer survivors may result from unclear roles for primary care providers...

Researchers from University of Texas, Health Science Center detail findings in cancer vaccines.
April 6, 2009... A new study, 'The nurse's role in the prevention of cervical cancer among underserved and minority populations,' is now available. According to a study from the United States, "Since the implementation of the Papanicolaou test, there has been a...

Institute of Hematology and Blood Transfusion details research in immunotherapy.
April 6, 2009... A report, 'Combined chemo- and immunotherapy of tumors induced in mice by bcr-abl-transformed cells,' is newly published data in Oncology Reports. "For our experiments we selected two oncogenic, bcr-abl-transformed mouse cell lines, viz. B210...

Advaxis Updates Phase I Trial Survival Data: 23% of Patients Still Surviving after 2+ Years.
April 6, 2009... Advaxis, Incorporated (OTCBB: ADXS), has updated survival data for its Phase I trial of its live Listeria vaccine ADXS11-001(formerly named Lovaxin-C) in patients with recurrent, metastatic, carcinoma of the cervix. While the Phase I safety...

Celldex Therapeutics to Present at the Needham & Company Cancer Therapeutics Conference.(Conference news)
April 6, 2009... Celldex Therapeutics, Inc. (NASDAQ: CLDX) announced that Thomas Davis, M.D., Senior Vice President and Chief Medical Officer of Celldex Therapeutics, Inc., will present at a the Needham & Company Cancer Therapeutics: Today & Tomorrow conference...

PRI's 'The World' Examines Success in Secrecy of Panama's HPV Vaccination Program.
April 6, 2009... Where health care advocates in the U.S. once struggled, Panama is finding success in efforts to introduce a vaccine for the cancer-causing human papillomavirus (HPV). PRI's "The World," the award-winning weekday global news program, probes the...

Stanford Cancer Expert Ronald Levy Will Receive King Faisal Prize in Medicine March 29.
April 6, 2009... The development of a drug that has revolutionized the treatment of many types of cancer has earned its inventor, Ronald Levy, MD, the 2009 King Faisal International Prize in Medicine (see also Stanford University Medical Center). More than...

Pitt vaccine to prevent colon cancer being tested in patients.
April 6, 2009... Researchers at the University of Pittsburgh School of Medicine have begun testing a vaccine that might be able to prevent colon cancer in people at high risk for developing the disease. If shown to be effective, it might spare patients the risk...

Study results from M.A. Habel and colleagues in the area of cancer vaccines published.(Report)
April 13, 2009... "Approximately 73 million adults in the United States report using the Internet as a source for health information. This study examines the quality, content, and scope of human papillomavirus (HPV) vaccine Internet news coverage starting on the...

Research from University of Pittsburgh in the area of peptide vaccine described.
April 13, 2009... According to a study from the United States, "No therapy has ever shown prolongation of survival in stage IV metastatic melanoma. The association of cytokine-induced autoimmunity with improved prognosis led us to investigate the effect of...

Researchers from University of Tsukuba discuss findings in cancer therapy.(Report)
April 13, 2009... New investigation results, 'The induction of tumor-specific CD4+ T cells via major histocompatibility complex class II is required to gain optimal anti-tumor immunity against B16 melanoma cell line in tumor immunotherapy using dendritic cells,'...

Data on cancer vaccines described by researchers at Johns Hopkins University, Department of Pathology.
April 13, 2009... Investigators publish new data in the report 'Low-dose radiation enhances therapeutic HPV DNA vaccination in tumor-bearing hosts.' "Current therapeutic approaches to treatment of patients with bulky cervical cancer are based on conventional in...

Data on cancer vaccines discussed by researchers at Wayne State University.
April 13, 2009... A report, 'Her-2 DNA versus cell vaccine: immunogenicity and anti-tumor activity,' is newly published data in Cancer Immunology, Immunotherapy. According to a study from the United States, "Direct comparison and ranking of vaccine formulations...

Data on cancer vaccines published by researchers at University of California, Department of Surgery.
April 13, 2009... Data detailed in 'Immunosensitization with a Bcl-2 small molecule inhibitor' have been presented. According to recent research published in the journal Cancer Immunology, Immunotherapy, "Several tumor immunotherapy approaches result in a low...

Scientists at University of Southampton, Cancer Sciences Division discuss research in cancer vaccines.
April 13, 2009... New investigation results, 'Fit for purpose? A case study: validation of immunological endpoint assays for the detection of cellular and humoral responses to anti-tumour DNA fusion vaccines,' are detailed in a study published in Cancer...

Study findings from Burnham Institute for Medical Research broaden understanding of cancer vaccines.(Report)
April 13, 2009... Scientists discuss in 'Salmonella typhimurium engineered to produce CCL21 inhibit tumor growth' new findings in cancer. "Intravenously-applied bacteria tend to accumulate in tumors and can sporadically lead to tumor regression. Systemic...

Data on cancer vaccines immunotherapy reported by researchers at Herlev University, Department of Hematology.(Report)
April 13, 2009... Fresh data on cancer vaccines are presented in the report 'The immunodominant HLA-A2-restricted MART-1 epitope is not presented on the surface of many melanoma cell lines.' "Among the relatively large number of known tumor-associated antigens...

New cervical intraepithelial neoplasia risk factors study findings recently were published by N. Munoz and co-researchers.
April 13, 2009... Researchers detail in 'Persistence of HPV infection and risk of high-grade cervical intraepithelial neoplasia in a cohort of Colombian women,' new data in cervical intraepithelial neoplasia. "Little is known about the dynamics of human...

Data from Kaohsiung Medical University, Department of Internal Medicine provide new insights into hepatitis C virus therapy.(Report)
April 13, 2009... New research, 'Treatment of chronic hepatitis C in Asia: when East meets West,' is the subject of a report. "The issue of best treatment for chronic hepatitis C virus (HCV) infection is in constant flux, not only in Western countries but also...

Data on immunization detailed by researchers at Karolinska Institut, Department of Oncology.(Report)
April 13, 2009... New research, 'HER-2/neu mediated down-regulation of MHC class I antigen processing prevents CTL-mediated tumor recognition upon DNA vaccination in HLA-A2 transgenic mice,' is the subject of a report. According to recent research from...

New Report Shows Record Number of Medicines in Development to Treat Leading Causes of Cancer.(Report)
April 13, 2009... Responding to President Obama's call for "a cure for cancer in our time," the Pharmaceutical Research and Manufacturers of America (PhRMA) delivered a new report on medicines in the research pipeline for cancer. The report shows that America's...

Geron Corporation Appoints Karin Eastham to Its Board of Directors.
April 13, 2009... Geron Corporation (Nasdaq:GERN) announced the appointment of Karin Eastham to its board of directors. Ms. Eastham will also serve as chair of the company's audit committee (see also Geron Corporation). Karin Eastham currently serves on the...

HPV vaccine may prevent preterm births.
April 13, 2009... Chronic human papilloma virus (HPV)-infections can lead to cellular changes in the cervix that can be a pre-stage to cervical cancer. Surgical treatment of these pre-stages gives an increased risk of preterm birth in subsequent pregnancies. As...

Most Recent Advances in Clinical Oncology.
April 13, 2009... Research and Markets (http://www.researchandmarkets.com/research/ea3737/recent_advances_in) has announced the addition of John Wiley and Sons Ltd's new report "Recent Advances in Clinical Oncology" to their offering (see also Research and...

Novavax Announces New Capital Infusion Through a Strategic Alliance with Cadila Pharmaceuticals of India.
April 13, 2009... Novavax Inc. (NASDAQ: NVAX) announced it has formed a joint venture with Cadila Pharmaceuticals Ltd. (Ahmedabad, India) to develop, manufacture and market vaccines, pharmaceuticals and diagnostic products in India. The joint venture will...

Researchers from University of London, Imperial College provide details of new studies and findings in the area of cancer vaccines.
April 20, 2009... According to a study from London, the United Kingdom, "Abnormal glycosylation is one of the hallmarks of the cancer cell and is associated with tumor invasion and metastasis. The development of tumor-associated carbohydrate antigen (TACA)...

Scientists at National Taiwan University release new data on cancer vaccines.(Report)
April 20, 2009... According to recent research from Taipei, Taiwan, "DNA vaccination is a novel immunization strategy that possesses many potential advantages over other vaccine strategies. One of the major difficulties hindering the clinical application of DNA...

Studies from University of Miami, Medical Department have provided new information about cancer vaccines.
April 20, 2009... According to recent research from the United States, "Established tumors suppress antitumor immune responses and induce tolerance by incompletely characterized mechanisms, and this phenomenon is an important barrier to tumor immunotherapy....

Study results from L. Aurisicchio and colleagues broaden understanding of cancer vaccines.
April 20, 2009... "Puepose: Oligodeoxynucleotides containing unmethylated CpG dinucleoticles induce innate and adaptive immunity through Toll-like receptor 9 (TLR9). In the present study, we have examined the ability of a novel agonist of TLR9, called...

Data on glioblastoma reported by M.M. Zulkifli and co-researchers.(Report)
April 20, 2009... "Newcastle disease virus ( NDV) is a virus of paramyxovirus family and lately has been studied for the treatment of cancer in human. In this study, we successfully determined the oncolysis potential of NDV vaccine, V4UPM tested on the human...

Data on tetanus reported by S.G.L. Quaak and co-researchers.
April 20, 2009... "The pDERMATT (plasmid DNA encoding recombinant MART-1 and tetanus toxin fragment-c) plasmid is a novel in-house developed anti-cancer vaccine which encodes a melanoma associated epitope (Mart]) and an immuno stimulatory sequence (tetanus toxin...

Data on cancer vaccines described by researchers at King's College London, King's College London School of Medicine.
April 20, 2009... Investigators publish new data in the report 'Anti-tumor immunity in a model of acute myeloid leukemia.' "Whole-cell vaccines allow the induction of anti-tumor immune responses without the need to define tumor antigens," scientists in London,...

Researchers from University of Western Ontario, Faculty of Science describe findings in cancer vaccines prevention.
April 20, 2009... Current study results from the report, 'Nutrition and the prevention and treatment of cancer: association of cytochrome P450 CYP1B1 with the role of fruit and fruit extracts,' have been published. "Recommendations for a healthy or prudent diet...

Data on life sciences published by researchers at University of Chicago, Brain Tumor Center.
April 20, 2009... Data detailed in 'Targeted therapies for malignant glioma: progress and potential' have been presented. According to recent research published in the journal BioDrugs, "Malignant gliomas represent one of the most aggressive forms of brain...

ImQuest Presentation at Keystone Symposium Focuses on Advancements in Their Cancer Research and Development Program.
April 20, 2009... ImQuest Life Sciences presented their latest biological results supporting the continued development of their novel small molecule piperazine compound for the treatment of solid tumors at the Targeted Cancer Therapeutics meeting held in...

PhRMA Honors Gardasil(r) Researchers With Discoverers Award.
April 20, 2009... The Pharmaceutical Research and Manufacturers of America (PhRMA) will honor recipients of its 2009 Discoverers Award and 2009 Clinical Trial Exceptional Service Award tonight at PhRMA's annual meeting in San Antonio, TX (see also Cancer...

Data on cancer vaccines reported by C. Porras and co-researchers.
April 27, 2009... According to recent research published in the journal Cancer Epidemiology Biomarkers & Prevention, "In a population-based study conducted in Guanacaste, Costa Rica, we investigated the human papillomavirus (HPV) types detected in 233 cases of...

Research data from Brussels Free University update understanding of cancer vaccines.
April 27, 2009... According to a study from Brussels, Belgium, "Dendritic cell (DC) immunotherapy for cancer certainly holds promises but definitely needs improvements, especially for enhancing tumor-specific responses able to eradicate preexisting tumors. To...

Research reports on cancer vaccines from SAIC-Frederick, Inc. provide new insights.(Report)
April 27, 2009... "In this study, we evaluated the applicability of a flow cytometry-based cytotoxicity (FC) assay previously developed by our laboratory, for monitoring cancer vaccine trials. The assay simultaneously measures effector cell degranulation and...

Scientists at McGill University discuss research in cancer vaccines.
April 27, 2009... "We analyzed data from a cohort of 553 women enrolled in the placebo arm of a randomized controlled trial of the human papillomavirus (HPV) 16/18 vaccine to study the timing of the occurrence of squamous intraepithelial lesions (SIL) or...

Studies conducted at University of Texas on cancer vaccines recently published.(Report)
April 27, 2009... According to recent research published in the journal Anticancer Research, "The objective of this study was to find whether the peptide LRMK linked to the N-terminus of HER-2, 774-788 and shorter peptides create a T helper antigen, which can...

Data on cancer vaccines reported by researchers at University of Heidelberg, Institute of Pathology.
April 27, 2009... Fresh data on cancer are presented in the report 'Cervical cancer control in the era of HPV vaccination and novel biomarkers.' "Infections with human papillomaviruses (HPV) are a necessary, but not sufficient cause of cervical cancer. Cervical...

Women's Health Advocates To Moms: We Can Beat Cervical Cancer!
April 27, 2009... Cervical cancer is preventable - if every woman knows about and benefits from the tools - the Pap test, HPV test and HPV vaccine - now available to protect them from this disease. That's the message that the Pearl of Wisdom(TM) Campaign to...

Supervised Exercise Therapy Can Lead to Improvements in COPD Symptoms.
April 27, 2009... Those suffering from chronic obstructive pulmonary disease (COPD) often complain that exercise is too exhausting and leaves them breathless. An article in the current issue of The New England Journal of Medicine reports that supervised exercise...