Cancer Gene Therapy Week articles from May 2009

Cancer Gene Therapy Week archives from May 2009

Study results from Brain Tumor Center provide new insights into brain cancer.
May 4, 2009... "Conditionally replicative adenoviruses (CRAds) are often evaluated in mice; however, normal and cancerous mouse tissues are poorly permissive for human CRAds. As the cotton rat (CR) is a semipermissive animal and the Syrian hamster (SH) is a...

Research conducted at University of Marburg, Medical Department has updated our knowledge about cancer gene therapy.
May 4, 2009... "Evaluation of: Sonoke S, Ueda T, Fujiwara K et al.: Tumor regression in mice by delivery of Bcl-2 small interfering RNA with pegylated cationic liposomes. Cancer Res. 68, 8843-8851 (2008). The induction of RNAi, which represents a powerful,...

Research reports on cancer gene therapy from I. Gentschev and colleagues provide new insights.(Report)
May 4, 2009... "Mammary cancers together with cancers of the skin account for about 60% of the total cancers occurring in dogs. The veterinary options for therapeutic management of canine mammary cancer are limited and prognosis for such patients is poor,"...

Recent studies by D. Hoangle and co-authors add new data to gene therapy findings.
May 4, 2009... "We have recently developed a non-cytopathic RNA replicon-based viral vector system based on the flavivirus Kunjin. Here, we illustrate the utility of the Kunjin replicon system for gene therapy," researchers in Brisbane, Australia report (see...

Studies in the area of life sciences reported from University of Alabama.
May 4, 2009... "The purpose of this article is to detail a percutaneous approach to placing peritoneal catheters using sonographic and fluoroscopic guidance. Fluoroscopic-assisted placement of these catheters has been previously described in the literature,"...

Bench to bedside: What's on the horizon.
May 4, 2009... The Annual Meeting of the American Association for Cancer Research remains the premier destination to showcase the newest and most exciting developments in cancer prevention and treatment. At the AACR 100th Annual Meeting 2009, Pasi A. Janne,...

Simulated gene therapy.
May 11, 2009... In a recent issue of The Journal of Chemical Physics, published by the American Institute of Physics (AIP), a group of researchers at the University of California, Berkeley and Los Alamos National Laboratory describe the first comprehensive,...

Data on cancer gene therapy detailed by researchers at INSERM.
May 11, 2009... According to recent research from France, "The lack of safe and efficient systemic gene delivery vectors has largely reduced the potential of gene therapy in the clinic. Previously, we have reported that polypropylenimine dendrimer PPIG3/DNA...

Findings from Qingdao University broaden understanding of cancer gene therapy.
May 11, 2009... According to a study from Qingdao, People's Republic of China, "CD59, belonging to membrane complement regulatory proteins (mCRPs), inhibits the cytolytic activity of complement and is over-expressed in solid cancers, including ovary cancer....

New cancer gene therapy study findings have been published by E. Fattori and colleagues.
May 18, 2009... According to recent research published in the journal Human Gene Therapy, "Aberrant Her2/neu expression is associated with the development of epithelial-derived human carcinomas and for this reason it is considered a good target for immunologic...

Studies from Chonnam National University, Medical Department have provided new information about cancer gene therapy.
May 18, 2009... According to recent research from South Korea, "Osteocalcin expression is restricted to osteoblasts and serum osteocalcin level is elevated in metastatic bone tumors including prostate tumours, which predominantly metastasizes to the bone and...

Studies from J. Morrison et al provide new data on cancer gene therapy.
May 18, 2009... "Gene and virotherapy of ovarian cancer, using type 5 adenovirus (Ad5), has demonstrated good activity in preclinical animal studies, particularly after intraperitoneal administration of virus; however, success in clinical trials has been...

New cancer gene therapy study results reported from Keimyung University, Institute for Medical Science.(Report)
May 18, 2009... Data detailed in 'Rottlerin induces apoptosis via death receptor 5 (DR5) upregulation through CHOP-dependent and PKC delta-independent mechanism in human malignant tumor cells' have been presented. "Rottlerin has been shown to induce...

New findings from Johns Hopkins Medical Institutions describe advances in cancer gene therapy.
May 18, 2009... Scientists discuss in 'NAC-1, a potential stem cell pluripotency factor, contributes to paclitaxel resistance in ovarian cancer through inactivating Gadd45 pathway' new findings in cancer gene therapy. According to recent research published in...

Recent studies from University of Toronto, Department of Medical Biophysics add new data to cancer gene therapy.(Report)
May 18, 2009... Research findings, 'The role of INI1/hSNF5 in gene regulation and cancer,' are discussed in a new report. According to a study from Toronto, Canada, "The precise modulation of chromatin dynamics is an essential and complex process that ensures...

Moving gene therapy forward with mobile DNA.
May 18, 2009... Gene therapy Gene therapy is the introduction of genetic material into a patient's cells resulting in a cure or a therapeutic effect. In recent years, it has been shown that gene therapy is a promising technology to treat or even cure several...