Cancer Gene Therapy Week articles from June 2004

Cancer Gene Therapy Week archives from June 2004

Scientists link gene family mutation to colon cancer.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Research published in the May 21 issue of Science shows mutations in a family of genes linked to more than a quarter of colon cancers, as well as other cancers. Scientists from the Johns Hopkins...

IMOxine produces immunological activity in those with solid-tumor malignancies.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Hybridon, Inc., (HBY) announced the presentation of new data from its on-going phase I oncology study of HYB2055 (IMOxine). In the trial, IMOxine was found to be safe and produced immunological...

Transcription-control mediated gene therapy blocks tumor angiogenesis.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Transcription-control mediated gene therapy blocks tumor angiogenesis. "A major drawback of current approaches to antiangiogenic gene therapy is the lack of tissue-specific targeting. The aim of...

Researchers discuss insights into p53 and cell death.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Understanding the molecular basis of the proapoptotic action of p53 can assist in reintroducing or reactivating p53 in human tumors, researchers say. According to recent research published in the...

Escape of mammary cell senescence can be seen in murine mammary tumor model.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Researchers discuss gene alterations observed in the murine mammary tumor model. "Human mammary epithelial cells emerge spontaneously from senescence, exhibiting eroding telomeric sequences, and...

New guide compiles information on colorectal cancer research.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Research and Markets, a research reports organization, has announced a new compendium of information on colorectal cancer. Entitled, Analysis of Colorectal Cancer R&D - the Complete Guide, the...

Hedgehog pathway implicated in ameloblastoma.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Curis, Inc., (CRIS), a therapeutic drug-development company, announced that the Journal of Oral Pathology and Medicine has published an article describing studies in which abnormal expression of the...

Combined therapy rallies caspase activation to staunch glioma growth.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Combined therapy rallies caspase activation to staunch glioma growth. According to a study from the United States, "specific activation of apoptosis in tumor cells offers a promising approach for...

Company initiates clinical trial of GCS-100LE in multiple cancers.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- GlycoGenesys, Inc., (GLGS), a biotechnology company focused on carbohydrate drug development, announced that it has initiated a phase I, dose-escalation, clinical trial in multiple solid tumor cancer...

Activation-induced cytidine deaminase (AID) may be a marker for B-CLL.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Study results suggest that activation-induced cytidine deaminase (AID) might have a role as a prognostic marker for B-CLL. "Activation-induced cytidine deaminase (AID) is essential for somatic...

Ets gene family may be involved in biological control of cancer progression.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Researchers find that Ets conversion may be important in the process of tumor progression. "The Ets family consists of a large number of evolutionarily conserved transcription factors, many of which...

Study may predict recurrence of head and neck cancer.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- A new study of tumor gene expression patterns may help doctors predict recurrence of head and neck cancer. Dr. Charles M. Perou, assistant professor of genetics and pathology and laboratory...

The p53 gene regulates estrogen receptor-alpha in breast cancer cells.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- The p53 gene regulates estrogen receptor-alpha in breast cancer cells. "The results presented here demonstrate that p53 upregulates estrogen receptor-alpha (ERalpha) expression in the human breast...

Cytokine gene therapy reverts melanoma growth in mice.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Cytokine gene therapy reverts melanoma growth in mice. "In the present study, interleukin (IL)-12 gene-transduced B78-H1 melanoma cells (B78/IL-12) were used in combination with IL-15 to treat...

Antigen Express wins Japanese patent for certain Ii-Key compounds.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Generex Biotechnology Corp. (GNBT) announced the award of Japan patent 3534761 to its Antigen Express affiliate for certain Ii-Key immunologically active compounds and their use in modifying immune...

The oncolytic adenovirus CG7870 attacks recurrent prostate cancers.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- The oncolytic adenovirus CG7870 attacks recurrent prostate cancers. "Human prostate-specific antigen (PSA) is a widely used tumor marker for prostate cancer diagnosis, prognosis and management. A...

Study: MetaMouse model predicts recurrence in human prostate cancer patients.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- A recent article in the Journal of Clinical Investigation by Gennadi Glinsky, et al., describes how scientists from AntiCancer, Inc., and the Sidney Kimmel Cancer Center have used AntiCancer's MetaMouse...

Recombinant endostatin can be synthesized in Chinese hamster ovary cells.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Recombinant endostatin can be synthesized in Chinese hamster ovary cells. According to recent research from Brazil, "endostatin, a carboxy-terminal fragment of collagen XVIII, has been shown to act...

Antisense oligonucleotide LErafAON enhances the work of standard chemotherapy.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Antisense oligonucleotide LErafAON enhances the work of standard chemotherapy. "Raf-1 protein serine/threonine kinase plays an important role in cell proliferation and cell survival. We have...

Combinatorial gene therapy offers antitumor protection to leukemia models.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Combinatorial gene therapy offers antitumor protection to leukemia models. "We report in a murine model of acute lymphoid leukemia L1210 the potent antitumor efficiency of a combinatorial delivery...

NCI awards funding for tumor-targeted siRNA therapeutic.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Intradigm Corp. announced that it has been awarded a phase I small business innovation research grant by the U.S. National Cancer Institute (NCI) to support development of the company's lead cancer...

Cationic lipid-DNA complexes slow glioblastoma growth in murine models.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Cationic lipid-DNA complexes slow glioblastoma growth in murine models. "The effect of a cationic liposome non-coding plasmid DNA complex on the growth of an intracerebral glioblastoma in an...

Company presents update on TNFerade at Digestive Disease Week.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- GenVec, Inc., (GNVC) announced that Kenneth J. Chang, MD, executive director, comprehensive digestive disease center, and head, gastrointestinal oncology, University of California, Irvine, California,...

Recombinant adenovirus p53 effects cancer cell apoptosis.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Oncologists in South Korea have demonstrated effective in vitro and in vivo adenovirus-mediated p53 gene transfection in cervical cancer cell lines and the resultant p53-dependent apoptosis of...

Mutations in gene encoding filamin B disrupt vertebral segmentation.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Mutations in the gene encoding filamin B disrupt vertebral segmentation. According to a study from Cedars Sinai Research Institute, "The filamins are cytoplasmic proteins that regulate the...

Nup88 mRNA overexpression associated with high aggressiveness of breast cancer.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Nup88 mRNA overexpression is associated with high aggressiveness of breast cancer "The nuclear pore complex protein Nup88 is overexpressed in tumor cells. Immunohistochemical studies have shown...

Dog genome may hold a wealth of information for humans.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- A new genetic analysis of man's best friend could help scientists explain why a border collie has knack for herding or why poodles sport a curly coat. In the May 21, 2004, issue of Science,...

p65 peptide identified that selectively inhibits NF-kappa B activation.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- A p65 peptide has been identified that selectively inhibits NF-kappa B activation. "Because of the critical role of the nuclear transcription factor NF-kappaB in inflammation, viral replication,...

Vascularizing tumors actively recruit bone marrow stromal progenitor cells.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Vascularizing tumors actively recruit bone marrow stromal progenitor cells. "Bone marrow-derived stromal cells (BMSC) possess a population of vascular progenitor cells that enable them to acquire a...

T cells and macrophages main BAFF-expressing cells in salivary glands from pSS.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- T cells and macrophages are the main BAFF-expressing cells in salivary glands from primary Sjogren syndrome. According to a study from France, "Primary Sjogren's syndrome (pSS) is an autoimmune...

Study looks at marrow stem cells and chemotherapy.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Inactivating a protective molecule in leukemic cells to make them more vulnerable to chemotherapy might also make healthy blood-forming cells more sensitive to the toxic effects of those same drugs....

Protein synthesis is necessary for oncogenic cellular transformation.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Researchers explore the roles of PI 3-kinase signaling pathway and the mRNA-binding protein YB-1 in protein synthesis and oncogenic cell transformation. According to recent research from the United...

Self-renewal capacity is a widespread property of neural crest precursor cells.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Self-renewal capacity is a widespread property of neural crest precursor cells "In vertebrates, trunk neural crest (NC) generates glia, neurons, and melanocytes. In addition, it yields...

Cyclin D1 overexpression is significant in thyroid tumors.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Cyclin D1 overexpression is significant in thyroid tumors. According to recent research published in the Journal of Pathology, "Cyclin D1 is a target molecule transcriptionally activated by...

Conditionally replicating adenoviruses with short hairpin RNAs silence genes.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Conditionally replicating adenoviruses with short hairpin RNAs silence genes. "RNA interference (RNAi) is a post-transcriptional silencing mechanism triggered by double-stranded RNA that was...

Bfl-1/A1 is a potent antiapoptotic stimulant in myeloma cells.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Bfl-1/A1 is a potent antiapoptotic stimulant in myeloma cells. According to a study from France, "terminal B-cell differentiation is a multistep process, from short-lived plasmablasts to mature...

Retrovirally mediated gas1 expression restricts glioma cell proliferation.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Retrovirally mediated gas1 expression restricts glioma cell proliferation. "We recently reported that the targeted expression of growth arrest specific 1 (Gas1) induces apoptosis in glioma cells....

2'-O-methyl- groups stabilize the binding of phosphorothioate antisense ODNs.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- 2'-O-methyl- groups stabilize the binding of phosphorothioate antisense ODNs. According to recent research from the United States, "antisense oligodeoxynucleotides (ODNs) have biological activity...

Therapeutic strategies targeting telomere maintenance defeat immortality.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Therapeutic strategies targeting telomere maintenance defeat immortality. "Telomeres are believed to stabilize chromosomes through several mechanisms that are dependent upon specific DNA-DNA and...

Inducible promoters aid gene expression in head and neck cancer cells.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Inducible promoters aid gene expression in head and neck cancer cells. According to a study from Germany, "the aim of gene therapy includes the tight spatial and temporal control of transgenic...

Stem cell factor gene-modified natural killer cells overwhelm tumor cells.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Stem cell factor gene-modified natural killer cells overwhelm tumor cells. According to recent research published in the journal Oncology Reports, "NK-92 cells are effective against a broad range...

Lead acetate exposure in vitro can damage melanoma cells.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Melanoma cells are sensitive to low-level lead exposure, researchers say. According to a study from Italy, "In this study, chromosomal damage induced in vitro by lead acetate in human melanoma...

Antisense oligonucleotides diminish breast cancer cell migration.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Antisense oligonucleotides diminish breast cancer cell migration. "MDA-MB-231 human breast cancer cells transfected with green fluorescent protein (GFP) were used as model to determine the...

CHEK2 mutation is linked to increased prostate cancer risk.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Study finds that the two truncating mutations of CHEK2 moderately increased the risk of developing prostate cancer in Polish men. "Variants in the CHEK2 have been found to be associated with...

X-ray beams trigger potent therapy against cancer.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- X-ray beams could kick-start genes into fighting cancer as an exciting new way of targeting therapy against the disease, according to new research. Cancer Research U.K. scientists have successfully...

TIMP-2 gene transfer halts H-ras-induced breast endothelial cell invasion.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- TIMP-2 gene transfer halts H-ras-induced breast endothelial cell invasion. According to a study from South Korea, "the matrix metalloproteases (MMPs) play important roles in invasion, metastasis...

Adenoviruses bearing gfp-zeocin fusion cassettes select p53-deficient cells.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Adenoviruses bearing gfp-zeocin fusion cassettes select for p53-deficient cells. "Two obstacles limiting the efficacy of nearly all cancer gene therapy trials are low gene transduction efficiency...

p16 Plasmids control telomerase activity in human gliomas.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- p16 Plasmids control telomerase activity in human gliomas. According to recent research from Japan, "the p16 and p53 tumor suppressor proteins, which are frequently altered in malignant gliomas,...

Bone cancer cells respond to HSV thymidine kinase-ganciclovir gene therapy.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Bone cancer cells respond to HSV thymidine kinase-ganciclovir gene therapy. According to recent research from Finland, "osteosarcoma and chondrosarcoma, the most prevalent primary malignant tumors...

Endothelial cell-specific human antibodies might retard tumor growth.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Endothelial cell-specific human antibodies might retard tumor growth. According to scientists in Germany, "we have isolated single-chain Fv fragments directed against human endothelial cells from...

Gene therapy tested to protect bone marrow during chemotherapy.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Researchers at the Center for Stem Cell and Regenerative Medicine and the Case Comprehensive Cancer Center at Case Western Reserve University and the Ireland Cancer Center at University Hospitals of...

NK4 transfection generates several modes of antitumor activity.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- NK4 transfection generates several modes of antitumor activity. "Tumor-stromal interactions, which are regulated by stromal-derived hepatocyte growth factor (HGF) and tumor-derived HGF inducers,...

Hapten receptors bear selective delivery of imaging and therapeutic agents.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Hapten receptors bear selective delivery of imaging and therapeutic agents. "Artificial recombinant receptors may be useful for selectively targeting imaging and therapeutic agents to sites of gene...

Family having hematopoietic cancers poses slight risk of offspring getting ALL.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Study finds that a history of hematopoietic malignancies (but not other types of malignancies) in family members slightly increases the risk of their children developing acute lymphoblastic leukemia...

Company announces new intravenous gene-delivery method.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Mirus Bio Corp. announced the development of Pathway IV gene delivery, a new method to efficiently deliver therapeutic genes to muscle via the blood stream. According to Mirus, this technique...

Microdissection-based genotyping aids reactive gliosis vs. glioma diagnosis.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Molecular anatomic pathology can detect loss of heterozygosity (LOH) in pathologic specimens, which distinguishes reactive states from neoplastic proliferations. According to published research...

ErbB3 is necessary for breast cancer proliferation.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Breast cancer proliferation associated with the ErbB family acts via the PI-3 kinase pathway, resarchers report. According to recent research from England, "The overexpression of the ErbB family...

Survivin, Bcl-2, p53 and bax expression increased in breast carcinoma.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Survivin, Bcl-2, p53 and bax expression are increased in breast carcinoma. According to published research from Turkey, "Survivin is a recently discovered member of the family of proteins that...

Alternative genetic pathway to human colorectal cancer found.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- An alternative genetic pathway to human colorectal cancer has been found. "At least two forms of genomic instability have been described in colorectal cancers (CRCs): microsatellite instability...

Cytochrome C depletion intensifies the immunogenicity of colon cancer cells.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Cytochrome C depletion intensifies the immunogenicity of colon cancer cells. According to researchers in France, "we and others have previously reported in an in vivo rat colon cancer cell model...

Pin1 may link signal transduction to cancer and Alzheimer disease.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Recent study results indicate that conformational changes following phosphorylation are a novel signaling mechanism pivotal in regulating many cellular functions. "Protein phosphorylation on...

Multicellular tumor spheroids model HSVtk/ganciclovir systems in vitro.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Multicellular tumor spheroids model HSVtk/ganciclovir systems in vitro. "We have developed multicellular spheroids (MCS) established from LM05e and LM3 spontaneous Balb/c-murine mammary...

Downregulated Bcl-2 or xIAP enhances the efficacy of breast cancer chemotherapy.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Downregulated Bcl-2 or xIAP enhances the efficacy of breast cancer chemotherapy. According to recent research from Portugal, "antiapoptotic genes such as bcl-2 or X-linked inhibitor of apoptosis...

Aurora-2 is a potential target for the treatment of pancreatic cancer.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Aurora-2 is a potential target for the treatment of pancreatic cancer. According to a study from the United States, "Aurora-2 is a serine threonine kinase that associates with the centrosome....

Administration route shapes the effects of IL-12-expressing dendritic cells.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Administration route shapes the effects of IL-12-expressing dendritic cells. According to published research from the United States, "gene-modified dendritic cells (DC) provide unique therapeutic...

Pharmacogenomic profiling of PI3K/PTEN-AKT-mTOR pathway in tumors elucidated.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Pharmacogenomic profiling of the PI3K/PTEN-AKT-mTOR pathway in common tumors has been elucidated. "The protein synthetic machinery is activated by a variety of genetic alterations during tumor...

Plasmid-based hormone therapy could improve disease or age-induced wasting.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Plasmid-based hormone therapy could improve disease or age-induced wasting. According to a study from the United States, "geriatric and cancer-afflicted patients often experience decreased quality...

Bikunin plus paclitaxel trims tumor burden and ascites in ovarian cancer models.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Bikunin plus paclitaxel trims tumor burden and ascites in ovarian cancer models. According to researchers in Japan, "our previous studies of intraperitoneal ovarian carcinoma in a mouse model...

CD28 costimulation triggers tumor recognition by modified T cells.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- CD28 costimulation triggers tumor recognition by modified T cells. "T cells engineered to express single-chain antibody receptors that incorporate TCR-zeta and cluster designation (CD)28 signaling...

Cell-line company adds Dr. Stephen Chang to scientific advisory board.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- MultiCell Technologies, Inc., (EXTI) announced that Stephen Mon Wei Chang, PhD, has joined the company's scientific advisory board (SAB). "Dr. Chang is the most recent noted scientist to join...

Dendritic cells made to overexpress CCL21 stimulate tumor immunity.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Dendritic cells made to overexpress CCL21 stimulate tumor immunity. According to published research from the United States, "to achieve in situ tumor antigen uptake and presentation, intratumoral...

NIH awards phase II SBIR to develop zebrafish apoptosis drug-screening assays.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Phylonix Pharmaceuticals, Inc., has received a phase II small business innovation grant (SBIR) from the National Cancer Institute to develop zebrafish apoptosis assays for drug screening. The...

Results on electroporation-enhanced DNA vaccine delivery presented at meeting.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Genetronics Biomedical Corp. (GEB), a company focused on cancer and other medical therapies based on electroporation-enhanced delivery of drugs, DNA vaccines, and genes, presented a poster in...

Lorus announces European patent to protect unique tumor suppressor.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Lorus Therapeutics, Inc.'s, wholly owned subsidiary, GeneSense Technologies, Inc., has been allowed a patent by the European Patent Office for its discovery of a gene, which suppresses the growth of...

MUC1 may indicate aggressive phenotypes in pancreatic neoplasia.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- MUC1 and MUC2 may be potential therapeutic targets in pancreatic cancer, researchers say. "MUCs are glycoproteins with various roles in homeostasis and carcinogenesis. Among other actions, MUC1 may...

Dr. Michael Fons tapped as executive director, corporate development.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Genetronics Biomedical Corp. (GEB) has appointed Michael Fons, PhD, MBA, as executive director, corporate development. Fons has extensive business development experience relating particularly to...

Modified thrombospondin-2 cDNA transduction stops tumor growth and angiogenesis.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Modified thrombospondin-2 cDNA transduction stops tumor growth and angiogenesis. According to published research from South Korea, "gene therapy represents a possible alternative to the chronic...

Folate receptors ensure correct delivery of tumor-selective gene therapy.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Folate receptors ensure correct delivery of tumor-selective gene therapy. According to a study from the United States, "gene therapy is a promising approach for the treatment of cancer. The main...

Hybrid LTR retroviruses seek and transfect tumor endothelial cells.
June 28, 2004... 2004 JUN 28 - (NewsRx.com & NewsRx.net) -- Hybrid LTR retroviruses seek and transfect tumor endothelial cells. According to recent research from England, "transcriptional targeting is an important aspect of developing gene therapy vectors...