Cancer Gene Therapy Week articles from December 2003

Cancer Gene Therapy Week archives from December 2003

Real-time imaging depicts how TRAIL can treat tumors.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Real-time imaging depicts how TRAIL can treat tumors. "Tumor necrosis factor-related apoptosis-inducing ligand ( TRAIL) has been shown to induce apoptosis in neoplastic cells. While many previous...

ONYX-015 augments radiotherapy directed against thyroid cancer cells.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- ONYX-015 augments radiotherapy directed against thyroid cancer cells. According to a study from Italy, "ONYX-015 is a genetically modified adenovirus with a deletion of the E1B early gene and...

Gene therapy containing p53 combines with CDDP to arrest liver tumor growth.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Gene therapy containing p53 combines with CDDP to arrest liver tumor growth. "Surgical resection is thought to be the best treatment for liver carcinoma, including hepatocellular carcinoma and...

PTEN overexpression squashes the migration of ovarian cancer cells.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- PTEN overexpression squashes the migration of ovarian cancer cells. "Peritoneal dissemination is the major progression pathway of ovarian cancer, and its control is important for improvement of the...

Fusion gene products facilitate the study of enzyme-mediated gene therapy.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Fusion gene products facilitate the study of enzyme-mediated gene therapy. According to recent research from Finland, "the fusion gene of herpes simplex virus thymidine kinase and green fluorescent...

Farnesyltransferase inhibitors in AML and myelodysplastic syndromes.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Farnesyltransferase inhibitors in AML and myelodysplastic syndromes. According to a study from the United States, "Farnesyltransferase inhibitors were initially developed as Ras inhibitors as they...

Two CD95 tumor classes with different sensitivities to antitumor drugs.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Two CD95 tumor classes with different sensitivities to antitumor drugs. According to recent research from the United States, "CD95 type I and II cells differ in their dependence on mitochondria to...

14-3-3 Sigma positively regulates p53 and suppresses tumor growth.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- 14-3-3 sigma positively regulates p53 and suppresses tumor growth. According to published research from the United States, "The 14-3-3 sigma (sigma) protein, a negative regulator of the cell cycle, is a...

Comparative transductions of breast cancer cells by three DNA viruses.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Comparative transductions of breast cancer cells by three DNA viruses. "Defining the ideal vectors to transduce breast cancer using viruses is currently under intense preclinical evaluation,"...

EZH2 is a marker of aggressive breast cancer.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- EZH2 is a marker of aggressive breast cancer. According to a study from the United States, "The Polycomb Group Protein EZH2 is a transcriptional repressor involved in controlling cellular memory and has...

Hpr6.6 protein mediates cell death from oxidative damage in MCF-7 breast cancer.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Hpr6.6 protein mediates cell death from oxidative damage in MCF-7 breast cancer. "Reactive oxygen species (ROS) cause cell death and are associated with a variety of maladies, from trauma and...

Choline phospholipid metabolism: A target in cancer cells?
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Choline phospholipid metabolism: A target in cancer cells? According to a study from the United States, "The experience of treating cancer over the past several decades overwhelmingly demonstrates that...

Drosophila genetics can be a screening model for metastasis.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Drosophila genetics can be a screening model for metastasis. "Cancer metastasis is a complex process involving many genes and pathways. This complexity hinders the identification of molecules...

Free radicals mediate cardiac toxicity induced by adriamycin.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Free radicals mediate cardiac toxicity induced by adriamycin. "Anthracycline antibiotics, including adriamycin (ADM), are widely used to treat various human cancers, but their clinical use has been...

KCl cotransport is an important modulator of cervical cancer growth and invasion.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- KCl cotransport is an important modulator of cervical cancer growth and invasion. According to a study from Taiwan, "Cervical cancer is a major world health problem for women, but the pathophysiology of...

Acid pH affects the distribution of chemotherapeutic agents in vitro.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Acid pH affects the distribution of chemotherapeutic agents in vitro. "Resistance to anticancer chemotherapies often leads to regional failure, and can be caused by biochemical and/or physiological...

High expression of CD55 by colorectal cancers is predictive of low survival.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- High expression of CD55 by colorectal cancers is predictive of low survival and recurrence. According to research published in the journal Cancer Immunology Immunotherapy, "this study prospectively...

Motility of colon cancer cells: modulation by CD44 isoform expression.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Motility of colon cancer cells: modulation by CD44 isoform expression. According to recent research from Canada, "The invasion of cancer cells at primary tumor sites and their migration during...

Multivitamin use and colorectal cancer incidence in a U.S. cohort.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Multivitamin use and colorectal cancer incidence in a U.S. cohort. According to a study from the United States, "Multivitamins contain several nutrients, including folic acid, that are hypothesized to...

NSAIDs inhibit colorectal neoplasia.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- NSAIDs inhibit colorectal neoplasia. "Nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit colorectal neoplasia, an effect that is associated with their ability to induce apoptosis. Although...

Peripheral blood mononuclear cells express different genes in kidney cancer.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Peripheral blood mononuclear cells have predictor genes and express certain proteins differently in renal cell carcinoma patients. "Expression profiling has demonstrated that transcriptomes of...

Detection of p53 mutations in precancerous gastric tissue.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Detection of p53 mutations in precancerous gastric tissue. According to a study from England, "Intestinal-type gastric cancer is preceded by gastritis and intestinal metaplasia. There is...

Rearranged cell activity enhances how RAD50 gene therapy affects angiogenesis.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Rearranged cell activity enhances how RAD50 gene therapy affects angiogenesis. According to published research from South Korea, "previous reports showed that human RAD50 (hRAD50) gene delivery...

SMAD4 gene therapy halts the invasiveness of pancreatic adenocarcinoma cells.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- SMAD4 gene therapy halts the invasiveness of pancreatic adenocarcinoma cells. "SMAD4 is a critical cofactor in signal transduction pathways activated in response to transforming growth factor-beta...

Genetic and epigenetic alterations as hallmarks of the intricate road to cancer.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Genetic and epigenetic alterations as hallmarks of the intricate road to cancer. "Despite the clonal origin of most tumors, their tremendous heterogeneity suggests that cancer progression springs...

Genomic instability and cancer.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Genomic instability and cancer. "Tumorigenesis can be viewed as an imbalance between the mechanisms of cell-cycle control and mutation rates within the genes. Genomic instability is broadly...

Physiological and molecular genetic alterations in head and neck cancer.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Physiological and molecular genetic alterations in head and neck cancer. According to published research from the United States, "Despite improvements in the diagnosis and management of head and neck...

Bone marrow evaluation in pediatric patients.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Bone marrow evaluation in pediatric patients. According to a study from the United States, "Pediatric bone marrow evaluation is often challenging, especially for pathologists with more experience...

Chromosomal translocations in human malignant hematopoiesis.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Chromosomal translocations in human malignant hematopoiesis. According to recent research published in the journal Pathologie Biologie, "The improvement of molecular biology techniques and human genome...

The proto-oncoprotein c-Fos negatively regulates hepatocellular tumorigenesis.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- The proto-oncoprotein c-Fos negatively regulates hepatocellular tumorigenesis. "Hepatocytes adopt an invasive and metastatic phenotype caused by the cooperation of transforming growth factor...

Antisense blockade of Stat5a/b promotes the apoptosis of lymphoid cells.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Antisense blockade of Stat5a/b promotes the apoptosis of lymphoid cells. "Stat5a and Stat5b exhibit 96% homology and are required for normal immune function. The present studies examined Stat5a/b...

Chromosomal abnormalities in secondary myelodysplastic syndromes and leukemias.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Chromosomal abnormalities in secondary myelodysplastic syndromes and leukemias. According to a study from France, "Secondary leukemias group essentially together myelodysplastic syndromes and acute...

Cytogenetic findings in adult de novo acute myeloid leukemia.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Cytogenetic findings in adult de novo acute myeloid leukemia. "During a 10-year period (1992 - 2001) in the region of Southern Denmark, 337 patients aged 15 years or older (range 16 - 93 years,...

Forty-seven children with from chronic myeloid leukemia over a 25-year period.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Forty-seven children with from chronic myeloid leukemia over a 25-year period. "To determine the diagnostic characteristics, blast crisis status, appropriate treatment, overall patient survival, and...

Proteomic approaches to biomarker discovery in lung cancers by SELDI technology.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Proteomic approaches to biomarker discovery in lung cancers by SELDI technology. According to recent research published in the journal Science in China Series C - Life Sciences, "The purpose of the...

Lung tumor suppressor TSLC1 binds MPP3; mutation in TSLC1 disrupts cell adhesion.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Lung tumor suppressor TSLC1 binds to MPP3; mutation in TSLC1 may disrupt cell-cell adhesion and contribute to lung cancer. "We have previously identified the tumor suppressor in lung cancer 1...

Cytogenetic abnormalities in malignant lymphoma and multiple myeloma.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Cytogenetic abnormalities in malignant lymphoma and multiple myeloma. "During the past few years, cytogenetic analysis of malignant proliferations contributed to the resolution of complex...

The role of erythropoietin in the anemia of myelodysplastic syndrome.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- The role of erythropoietin in the anemia of myelodysplastic syndrome. "Although erythropoietin (EPO) deficiency is not responsible for the anemia of myelodysplasia, pharmacologic doses of...

BRAF and K-ras gene mutations in human pancreatic cancers.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- BRAF and K-ras gene mutations in human pancreatic cancers. "We investigated the frequency of BRAF mutations in human pancreatic cancer specimens to determine its role in the development of...

Eric von Hofe named VP of technology development.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Generex Biotechnology, Inc., (GNBT) announced that its Antigen Express subsidiary for developing novel immunomedicines has appointed Eric von Hofe, PhD, as vice president of technology development...

The Kruppel-like transcription factor 6 gene in sporadic pituitary tumors.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- The Kruppel-like transcription factor 6 gene in sporadic pituitary tumors. "The oncogenes and/or tumor suppressor genes which may be involved in the transformation process for the vast majority of...

Genetic mapping of allelic loss on chromosome 6q in prostate carcinoma.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Genetic mapping of allelic loss on chromosome 6q in prostate carcinoma. According to a study from Japan, "A number of genetic events have been reported in prostate carcinogenesis, including frequent...

No association of germline alteration of MSR1 with prostate cancer risk.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- No association of germline alteration of MSR1 with prostate cancer risk. "The macrophage scavenger receptor 1 gene (MSR1) was recently identified as a candidate susceptibility gene for hereditary...

Molecular subclassification of renal tumors and discovery of diagnostic markers.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Molecular subclassification of renal tumors and discovery of diagnostic markers. According to a study from the United States, "We analyzed the expression profiles of 70 kidney tumors of different...

First commercially licensed gene therapy drug approved for production.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Approval to produce the world's first commercially licensed gene therapy medication, a treatment for head and neck squamous cell carcinoma (HNSCC), has been granted to the Shenzhen SiBiono Gene...

Galectin-3 is expressed in higher amount only in papillary thyroid carcinomas.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Galectin-3 is expressed in both benign, malignant thyroid tumors; is only higher in papillary carcinomas. According to a study from Japan, "We measured the relative expression levels of galectin-3...

Low monoamine oxidase B in peripheral organs in smokers.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Low monoamine oxidase B in peripheral organs in smokers. According to recent research published in the journal Proceedings of the National Academy of Sciences USA, "One of the major mechanisms for...

The quest for a tumor suppressor gene phenotype.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- The quest for a tumor suppressor gene phenotype. According to published research from Canada, "Our current definitions of the tumor suppressor gene (TSG) have been guided by the identification of the...

Polymorphisms in DNA repair genes may be linked to immunosuppression, cancer.
December 1, 2003... 2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Polymorphisms in DNA repair genes may be linked to immunosuppression, cancer. "When the sun damages the skin, it also impairs the DNA. The DNA repair system is needed to maintain the genetic...

Suicide gene therapy bystander effects correlate with cell communication.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Suicide gene therapy bystander effects correlate with cell communication. "Gap junctional intercellular communication (GJIC) has been shown to be involved in the bystander effect through herpes...

Calponin hI protects peritoneal cells from melanoma invasion.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Calponin hI protects peritoneal cells from melanoma invasion in mice. "In a previous study, we demonstrated that calponin hI suppressed tumor growth of transformed cells and that the peritonitis...

Medicinal herbs target distinctive genes to control tumor proliferation.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Medicinal herbs target distinctive genes to control tumor proliferation. "Although the physiological actions of many herbs are gradually being elucidated at the molecular level, it remains unclear...

Antisense inhibition of laminin-8 reduces human glioma invasion in vitro.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Antisense inhibition of laminin-8 reduces human glioma invasion in vitro. "Using gene array technology, we recently observed for the first time an up-regulation of laminin alpha4 chain in human...

E2F decoy oligodeoxynucleotides block human tumor cell growth.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- E2F decoy oligodeoxynucleotides block human tumor cell growth. "Abnormal cell proliferation, largely dependent upon deregulation of cell-cycle regulatory proteins, is an important feature of...

Farnesyltransferase inhibitors in AML and myelodysplastic syndromes.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Farnesyltransferase inhibitors in AML and myelodysplastic syndromes have been investigated. According to a study from the United States, "Farnesyltransferase inhibitors were initially developed as...

Discovery of cytochrome p450 1B1 inhibitors as new promising anticancer agents.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Cytochrome p450 1B1 inhibitors have been called new promising anticancer agents. According to published research from South Korea, "Human cytochrome P450 (CYP)1B1 is a major enzyme for carcinogenic...

14-3-3 Sigma positively regulates p53 and suppresses tumor growth.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- 14-3-3 Sigma positively regulates p53 and suppresses tumor growth. According to published research from the United States, "The 14-3-3sigma (sigma) protein, a negative regulator of the cell cycle,...

Comparative transductions of breast cancer cells by three DNA viruses.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Transductions of breast cancer cells by three DNA viruses compared. "Defining the ideal vectors to transduce breast cancer using viruses is currently under intense preclinical evaluation,"...

Hpr6.6 protein mediates cell death from oxidative damage in MCF-7 breast cancer.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Hpr6.6 protein mediates cell death from oxidative damage in MCF-7 breast cancer. "Reactive oxygen species (ROS) cause cell death and are associated with a variety of maladies, from trauma and...

Integrated clinico-genomic models for breast cancer outcomes prediction.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Outcome predictions are made for integrated clinico-genomic models for breast cancer. According to recent research from the United States, "Genomic data, particularly genome-scale measures of gene...

Choline phospholipid metabolism: A target in cancer cells?
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Choline phospholipid metabolism as a target in cancer cells is studied. According to a study from the United States, "The experience of treating cancer over the past several decades overwhelmingly...

Drosophila genetics can be a screening model for metastasis.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Drosophila genetics can be a screening model for metastasis. "Cancer metastasis is a complex process involving many genes and pathways. This complexity hinders the identification of molecules...

CCI-779 prevents abnormal brain cell growth and reverses seizures in lab mice.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Investigators at St. Jude Children's Research Hospital used an experimental anticancer drug to prevent or reverse abnormal brain cell growth that is caused by lack of the anticancer gene Pten. The...

KCl cotransport is an important modulator of cervical cancer growth and invasion.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- KCl cotransport is an important modulator of cervical cancer growth and invasion. According to a study from Taiwan, "Cervical cancer is a major world health problem for women, but the...

Acid pH affects the distribution of chemotherapeutic agents in vitro.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Acid pH affects the distribution of chemotherapeutic agents in vitro. "Resistance to anticancer chemotherapies often leads to regional failure, and can be caused by biochemical and/or physiological...

Sloan-Kettering catalyzes screening effort for anticancer agents.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- ChemBridge Research Laboratories, LLC, (CRL) and the Experimental Therapeutics Center (ETC) at Memorial Sloan-Kettering Cancer Center (MSKCC) announced a collaborative agreement where CRL will provide...

Motility of colon cancer cells: modulation by CD44 isoform expression.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Modulation of colon cancer cell motility by CD44 isoform expression have been investigated. According to recent research from Canada, "The invasion of cancer cells at primary tumor sites and their...

Multivitamin use and colorectal cancer incidence in a U.S. cohort.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Multivitamin use and colorectal cancer incidence is described in a U.S. cohort. According to a study from the United States, "Multivitamins contain several nutrients, including folic acid, that are...

NSAIDs inhibit colorectal neoplasia.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- By inducing apoptosis, NSAIDs inhibit colorectal neoplasia. "Nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit colorectal neoplasia, an effect that is associated with their ability to induce...

Detection of p53 mutations in precancerous gastric tissue.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- p53 Mutations have been seen in precancerous gastric tissue. According to a study from England, "Intestinal-type gastric cancer is preceded by gastritis and intestinal metaplasia. There is...

CDKN2A has a missense mutation in families with susceptibility to melanoma.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- CDKN2A has a missense mutation in families with susceptibility to uveal, cutaneous melanoma. "A few families have been described whose members are affected by either cutaneous melanoma (CM) or uveal...

Genetic and epigenetic alterations as hallmarks of the intricate road to cancer.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Genetic and epigenetic alterations are hallmarks along the intricate road to cancer. "Despite the clonal origin of most tumors, their tremendous heterogeneity suggests that cancer progression...

Genomic instability and cancer.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- "Tumorigenesis can be viewed as an imbalance between the mechanisms of cell-cycle control and mutation rates within the genes. Genomic instability is broadly classified into microsatellite instability...

Genomic microarrays in human genetic disease and cancer.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Performance characteristics of genomic microarrays in human genetic disease and cancer have been presented. According to a study from the United States, "Alterations in the genome that lead to...

Physiological and molecular genetic alterations in head and neck cancer.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Physiological and molecular genetic alterations in head and neck cancer reviewed. According to published research from the United States, "Despite improvements in the diagnosis and management of...

Bone marrow evaluation in pediatric cancer patients.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Bone marrow was evaluated in pediatric patients with hematologic malignancies. According to a study from the United States, "Pediatric bone marrow evaluation is often challenging, especially for...

Chromosomal translocations in human malignant hematopoiesis.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Chromosomal translocations seen in human malignant hematopoiesis. According to recent research published in the journal Pathologie Biologie, "The improvement of molecular biology techniques and...

The proto-oncoprotein c-Fos negatively regulates hepatocellular tumorigenesis.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- The proto-oncoprotein c-Fos negatively regulates hepatocellular tumorigenesis. "Hepatocytes adopt an invasive and metastatic phenotype caused by the cooperation of transforming growth factor...

Chromosomal abnormalities in secondary myelodysplastic syndromes and leukemias.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Chromosomal abnormalities seen in secondary myelodysplastic syndromes and leukemias. According to a study from France, "Secondary leukemias group essentially together myelodysplastic syndromes and...

Cytogenetic findings in adult de novo acute myeloid leukemia.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Researchers report cytogenetic findings in adult de novo acute myeloid leukemia. "During a 10-year period (1992-2001) in the region of Southern Denmark, 337 patients aged 15 years or older (range...

Forty-seven children with chronic myeloid leukemia over a 25-year period.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Researchers in Taiwan reviewed cases of pediatric chronic myeloid leukemia over a 25-year period. "To determine the diagnostic characteristics, blast crisis status, appropriate treatment, overall...

Proteomic approaches to biomarker discovery in lung cancers by SELDI technology.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Proteomic approaches to biomarker discovery in lung cancers by SELDI technology have been reported. According to recent research published in the journal Science in China Series C - Life Sciences,...

Cytogenetic abnormalities in malignant lymphoma and multiple myeloma.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- Cytogenetic abnormalities analyzed in malignant lymphoma and multiple myeloma. "During the past few years, cytogenetic analysis of malignant proliferations contributed to the resolution of complex...

The role of erythropoietin in the anemia of myelodysplastic syndrome.
December 8, 2003... 2003 DEC 8 - (NewsRx.com & NewsRx.net) -- The role of erythropoietin in the anemia of myelodysplastic syndrome has been repoted by researchers in the U.S. "Although erythropoietin (EPO) deficiency is not responsible for the anemia of...