Anti-Infectives Week articles from September 2003

Anti-Infectives Week archives from September 2003

Heterologous flaviviruses alter the outcomes of human yellow fever infections.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Heterologous flaviviruses alter the outcomes of human yellow fever infections. According to recent research published in the American Journal of Tropical Medicine and Hygiene, "using a recently...

Duke investigators develop a clinical model of dermal wound angiogenesis.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Duke investigators develop a clinical model of dermal wound angiogenesis. "Full-thickness dermal biopsies were performed in healthy volunteers to establish the range of angiogenic responses in wound...

Immature dendritic cells have a receptor for human mannan-binding lectin.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Monocytes and dendritic cells produce mannan-binding lectins, and immature dendritic cells have an upregulated receptor for some. "Mannan-binding lectin (MBL) is a collectin synthesized by the...

Gallerimycin, a moth-derived antifungal peptide, isn't active against yeast.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- A new antifungal discovered in wax moth, gallerimycin, is not active against yeast. According to published research from Germany, "A novel defensin-like peptide was identified in the greater wax...

Drugs must target particular compartment where protein they act upon is located.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Drugs must be designed to reach the particular compartment in which the protein they act upon is, within the cell. "One of the more overlooked aspects of drug action and delivery is the...

Homograft endocarditis can be caused by Rhodotorula mucilaginosa.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- A healthy man with a case of aortic homograft endocarditis was found to have a fungal infection with Rhodotorula mucilaginosa. According to published research from Switzerland, "Serious infections...

Resistance may occur in bacteria if innate antibiotic proteins are used.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- There may be a risk involved in use of innate antibiotic molecules against bacterial infection. According to a study from Canada, "A remarkable range of novel antibiotics is attracting increasing...

Newly discovered inhibitors of bacterial lactamases may prevent resistance.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- The most important antibiotics in general use today are the b-lactam family of products, but the medical community faces a serious problem with these antibiotics: the increasing development of drug...

World Health Organization: Farmers should cut antibiotic use.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Farmers worldwide should take a lesson from Danish bacon producers and reduce the use of antibiotics on their livestock to help stem the growth of drug-resistant bacteria in humans, the U.N. health...

N- and C-terminal modifications of negamycin affect antibacterial activity.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- N- and C-terminal modifications of negamycin affected the drug's antibacterial activity. "Negamycin 1 is a bactericidal antibiotic with activity against Gram-negative bacteria, and served as a...

Vancomycin-resistant infections are low among liver transplant candidates.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Vancomycin-resistant infections are low among liver transplant candidates. "The orthotopic liver transplant (OLT) population has been particularly affected by the increase in vancomycin-resistant...

Several factors contribute to treatment failure in chronic hepatitis C.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Several factors contribute to treatment failure in chronic hepatitis C. "The treatment of chronic hepatitis C is currently based on a combination of pegylated interferon (IFN)-alpha and ribavirin....

Nramp gene determines efficacy of mycobacteria-based asthma treatment.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- The human Nramp gene determines the efficacy of mycobacteria-based asthma treatment. "Genes controlling antibacterial resistance may be important in the hygiene hypothesis, which states that lack of...

Epidemiology of sporadic bloody diarrhea in rural Western Kenya reported.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- The epidemiology of sporadic bloody diarrhea in rural Western Kenya was described in a recent issue of the American Journal of Tropical Medicine and Hygiene. According to recent research from the...

New method available for detecting toxic mold.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Atlanta, Georgia-based indoor air quality company, Air Quality Sciences, Inc., (AQS), is offering a new analysis to test for Stachybotrys chartarum, often referred to as toxic mold, in a fungal sample....

Grants to fund rapid, portable detection systems for HIV, blood lead.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Alderon Biosciences of Research Triangle Park, North Carolina, announced the award of two new research grants. As the original developer and manufacturer of the LeadCare, a U.S. Food and Drug...

Antimicrobial cocktail may reduce bacteria in fresh-cut produce.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- An antimicrobial cocktail consisting of phages and the bacteriocin nisin, may prove effective at decontaminating fresh-cut produce, say researchers from Maryland and West Virginia. Although the...

Caspofungin is first approved agent in new class of antifungals.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Caspofungin is the first agent in new class of antifungals approved in the United States. According to a study from the United States, "Caspofungin (Cancidas, Merck and Company, Inc.) is the first...

Cefuroxime axetil tablets - generic equivalent of Ceftin - launched.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- IVAX Corp. (IVX) announced its wholly owned subsidiary, IVAX Pharmaceuticals, Inc., is distributing cefuroxime axetil tablets in 250 mg and 500 mg dosage strengths. Cefuroxime axetil is the generic...

Resistance mutation patterns different in subtype B and E HIV strains.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- The pattern of drug resistance mutations varies by HIV subtype. "An increasing number of HIV-1-infected patients living in developing countries now have access to antiretroviral drugs," scientists...

Company expands Ramoplanin program with launch of infection control study.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- The clinical development program for Genome Therapeutics' (GENE) product candidate, Ramoplanin, has been expanded to investigate the role of the novel antibiotic in controlling the spread of important...

E Med Future begins NeedleZap distribution in Uganda.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- E Med Future, Inc., (EMDF), a Columbus, Ohio-based manufacturer of NeedleZap, a medical device that disintegrates used hypodermic needles, announced the company's expansion into Uganda through its...

Integron-bearing but drug-susceptible E. coli strains found in Rio Grande.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Intergron-bearing - but drug-susceptible - strains of E. coli have been isolated from the Rio Grande. "Municipal and agricultural pollution affects the Rio Grande, a river that separates the United...

New patents granted on oral-dosed, broad-spectrum immune activators.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Hemispherx Biopharma, Inc., (HEB), a company involved in the experimental-stage development of immune based therapies primarily addressing the diseases of Chronic Fatigue Syndrome, HIV/AIDS, and HPV,...

The structure of a key enzyme solved.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- A European team of scientists from the University of Dundee (UK), the Technical University of Munich (Germany), and the European Synchrotron Radiation Facility, ESRF, (France) have determined the...

Improved bacteriophage construction methods developed.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Scientists in the United States have made several improvements to the standard methods of developing bacteria-eating microbes. According to recent research published in the journal FEMS...

Amodiaquine with SP superior to chloroquine for first-line malaria treatment.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Amodiaquine (AQ) with SP is superior to chloroquine (CQ) for first-line malaria treatment. In a recent study in Africa, the safety and the efficacy of three potential CQ replacement regimens - AQ...

Antimalarial action explained by new report.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- A molecular target for the class of antimalaria drugs called artemisinins has been identified, researchers report. Artemisinins have become increasingly important for treating malaria as resistance...

Burn injury management product sales will double.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Burn injury management products will show double-digit gains in the coming years, according to a new study released by Kalorama Information. Although only one part of the approximately $1.5 billion...

Schistosomiasis symptoms in Nigeria include gynecological manifestations.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Schistosomiasis symptoms in Nigeria include gynecological manifestations. "The investigation on the prevalence of patent and clinically severe infections with Schistosoma haematobium was carried out...

GSK's Dr. Charles Grier joins board of structure-guided drug discovery company.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Affinium Pharmaceuticals, a company focused on structure-guided drug discovery, announced the appointment of Dr. Charles "Bucky" Grier to the board of directors. Grier is a director at GSK...

Small interfering RNAs inhibit pathological prion protein accumulation.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Small interfering RNAs inhibited pathological prion protein accumulation. According to a study from France, "Development of transmissible spongiform encephalopathies (TSEs) pathogenesis requires...

Adjunctive interleukin-2 does not improve anti-TB treatment efficacy.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Recombinant interleukin (IL)-2 does not improve the outcome of anti-tuberculosis treatment. IL-2 "has a central role in regulating T-cell responses to Mycobacterium tuberculosis," researchers in...

Infectious disease-focused company approved for AMEX.
September 1, 2003... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Immtech International, Inc., (IMM) announced its common stock has been approved for listing on the American Stock Exchange (AMEX). Immtech is expected to have Bear Wagner Specialists, LLC, as the...

Structure-based design of agents target the bacterial ribosome.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- A series of potential drugs have been identified by structure-based design to target the bacterial ribosome. According to a study from England, "Rational structure-based drug design has been...

Cyclic mechanisms characterize the nature of biofilms and gene transfer.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- Cyclic mechanisms characterize the nature of biofilms and gene transfer. According to recent research published in the journal Current Opinion in Biotechnology, "there has been much interest in...

An electrochemical method can detect viable Listeria monocytogenes in milk.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- An electrochemical method can detect viable Listeria monocytogenes directly cultured in milk. "Growth of Listeria monocytogenes in a Listeria enrichment broth (LEB) was automatically monitored by...

Most resistance to anti-HIV drugs created by good pill-taking patients.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- Resistance mutations to anti-HIV medications are more likely to occur in patients who take most of their medications rather than in those who don't, according to AIDS specialists at the University of...

Biologist finds HIV gene makes a human gene turn bad.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- A human gene named ATR normally protects people by preventing the replication of cells damaged by radiation or toxic chemicals. Now, Utah and New York researchers have discovered how a gene in the AIDS...

Oral antibiotics, early hospital discharge manage low-risk febrile neutropenia.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- Oral antibiotics, early hospital discharge can manage low-risk febrile neutropenia. According to recent research published in the British Journal of Cancer, "Neutropenic sepsis remains a potentially...

Intracellular pathogens like Listeria monocytogenes can be targeted.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- The autophagy mechanism can also be applied to intracellular pathogens like Listeria monocytogenes. "Autophagy is an important constitutive cellular process involved in size regulation, protein...

Betalactams, with epigallocatechin gallate, have antibacterial activity.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- Betalactams, with epigallocatechin gallate, have antibacterial activity. "The combined effects of (neg)-epigallocatechin gallate (EGCg) and betalactams were investigated against various...

Marines contract for portable device to detect bioterrorism agents.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- Implant Sciences Corp. (IMX) has been contracted by the U.S. Marine Corps to develop a field-portable instrument capable of quickly detecting and identifying a wide range of chemical warfare agents in...

Ciprofloxacin GR trial among highlights of company's second quarter.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- Depomed, Inc., (DMI) announced a net loss of $7,168,000, or $0.30 per share, for the quarter ended June 30, 2003, compared to a net loss of $7,000,000, or $0.50 per share, for the quarter ended June 30,...

NeedleZap maker announces first quarterly profit.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- E Med Future, Inc., (EMDF), manufacturer of NeedleZap, a medical device that disintegrates used hypodermic needles, announced a quarterly profit of $50,669 for the second quarter of 2003, the first...

Net loss of $0.54 per share reported by anti-infective agent developer.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- Vicuron Pharmaceuticals, Inc., (MICU; MICU) reported financial results for the 3 and 6-month periods ended June 30, 2003. Total revenues for the second quarter of 2003 were $2.3 million compared...

Ramoplanin maker reports net losses for second quarter, 6 months.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- Genome Therapeutics Corp. (GENE) reported financial results for the second quarter and 6 months ended June 28, 2003. For the second quarter of 2003, the company reported a net loss, before charges...

FDA approves commercialization of DisperMox.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- Ranbaxy Pharmaceuticals, Inc., (RPI), a wholly owned subsidiary of Ranbaxy Laboratories, Ltd., (RLL) announced that RLL had received approval from the U.S. Food and Drug Administration to market...

HIV M184V mutation linked to viroimmunologic discordant response to HAART.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- The M184V mutation in HIV reverse transcriptase is linked to a viroimmunologically discordant response to treatment. "Whether highly active antiretroviral therapy (HAART) should be modified in...

Antagonists of the E1-E2 protein interaction inhibit HPV DNA replication.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- Small molecule antagonists of the E1-E2 protein interaction inhibited human papillomavirus DNA replication. "Human papillomavirus (HPV) DNA replication is initiated by recruitment of the E1...

Adaptor TRIF needed for TLR3- and TLR4-mediated antiviral defense.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- The adaptor TRIF is needed for TLR3- and TLR4-mediated antiviral defense. "Stimulation of Toll-like receptors (TLRs) triggers activation of a common MyD88-dependent signaling pathway as well as a...

Company increases influenza vaccine availability to 19 million doses.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- Henry Schein, Inc., (HSIC) announced that it has begun to ship what it anticipates to be more than 19 million doses of influenza vaccine for the 2003-2004 influenza season. This shipment represents...

Postpartum meningococcal meningitis results from combined analgesia.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- Postpartum meningococcal meningitis results from combined analgesia. "We present a case of bacterial meningitis in a 32-year-old parturient following combined spinal-epidural analgesia for labor....

The peptidoglycan recognition protein M.mPGRP-L has good antibacterial activity.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- The peptidoglycan recognition protein M.mPGRP-L is expressed in the liver and found in serum; it has activity against peptidoglycan from E. coli, S. aureus, and B. pertussis. According to a study...

Endosafe-PTS launched to detect microbial contaminants in drugs, devices.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- Charles River Laboratories International, Inc., (CRL) has launched the Endosafe-PTS. The PTS is a portable test system based on the Limulus Amebocyte Lysate (LAL) assay. The LAL test is used to...

What causes prion infectivity?
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- Two important questions face biologists studying the infectious proteins called prions: What stops prions that infect one species from infecting another species and what causes the invisible...

Patent granted to biologically active molecules from the environment.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- Diversa Corp. (DVSA) announced that it has been issued U.S. patent no. 6,602,675, expanding its position for identifying biologically active molecules from the environment. The patent is directed...

Crotoxin is the active Crotalus inhibitor of macrophage phagocytosis.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- Crotoxin is the active factor in Crotalus durissus terrificus snake venom that inhibits macrophage phagocytosis, but not by means of opioid receptors. According to a study from Brazil, "Previous...

MgrA is transcriptional regulator in S. aureus, like MarR in E. coli.
September 8, 2003... 2003 SEP 8 - (NewsRx.com & NewsRx.net) -- MgrA is a transcriptional regulator in Staphylococcus aureus, similar to MarR in E. coli. According to recent research published in the Journal of Bacteriology, "The virulence determinants of...

Structures of five antibiotics bound to large ribosomal subunit reported.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- Researchers have reported the structures of five antibiotics bound at the peptidyl transferase center of the large ribosomal subunit. "Structures of anisomycin, chloramphenicol, sparsomycin,...

Arsenic-eating bacteria may save lives and clean mines.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- Melbourne scientists plan to harness the strange appetite of newly discovered Australian bacteria to help purify arsenic-contaminated water. The research group, led by microbiologist Dr. Joanne...

Linezolid highly active against anaerobic bacteria.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- Linezolid is highly active against anaerobic bacterial pathogens. In a recent study from France, "minimal inhibition concentrations (MICs) were determined" for LZD "and compared with those of...

Program controls vancomycin-resistant Enterococcus among inpatients.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- A surveillance system implemented at the University of Virginia Health Systems successfully controlled vancomycin-resistant Enterococcus among hospital inpatients. "We sought to determine the...

Congo red analogs potential transmissible spongiform encephalopathy agents.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- Congo red analogs show promise as agents against transmissible spongiform encephalopathies. According to a study from Wales, "The synthesis of analogues of the amyloid stain Congo red as potential...

Hepatitis A virus replication parallels its pathogenesis.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- Hepatitis A virus replication parallels its pathogenesis. According to recent research published in the Journal of Medical Virology, "the correlation between the length of viremia as detected by...

Gender influences the response to highly active antiretroviral therapy.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- Gender influences the response to highly active antiretroviral therapy. "To determine whether CD4 cell count response to virus suppression during highly active antiretroviral therapy differs...

ABthrax wins fast-track designation.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- Human Genome Sciences, Inc., (HGSI) announced that it has received a fast track product designation from the U.S. Food and Drug Administration (FDA) for ABthrax (PA mAb), a drug for the prevention of...

Diallyl disulfide prevents gentamicin nephrotoxicity.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- An antioxidant derived from garlic can prevent kidney damage induced by antibiotic treatment with gentamicin. "Experimental evidences suggest a role of reactive oxygen species in...

Antimicrobial peptides derived from animal food lysozyme are bactericidal.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- Some peptides derived from lysozyme in animal food products have strong antibacterial activity and might be useful as antibacterial food additives. "Antimicrobial peptides developed from proteins...

E. coli beta-lactamase confirmation method altered for false-positives.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- Beta-lactamase confirmation methods for E. coli have been changed to reduce false-positive results. According to published research from the United States, "To determine whether confirmatory tests...

Dormant bugs dodge antibiotics.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- A new way to attack harmful bacteria by affecting normal growth has been discovered by scientists from Aberystwyth, Wales. The research was presented by Dr. Adriana Ravagnani at the Society for General...

Study of Burkholderia strains yields promising leads.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- People with weakened immune systems, including patients with cystic fibrosis, could be better protected in the future from a highly resilient bacteria thanks to work by medical scientists from the...

Structure-based phenotyping predicts HIV-1 protease inhibitor resistance.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- Structure-based phenotyping can predict HIV-1 protease inhibitor resistance. "Mutations in HIV-1 drug targets lead to resistance and consequent therapeutic failure of antiretroviral drugs....

Progress made against deadly bug.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- Scientists from the Institute for Animal Health announced progress toward controlling the deadly E. coli bacterium that causes food poisoning and kidney failure at the recent Society for General...

Disposal company reports increased revenues for fourth quarter and year.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- Sharps Compliance Corp. and subsidiaries (SCOM) announced its operating results for the fourth quarter and fiscal year 2003. For the fiscal year ended June 30, 2003, the company generated revenues...

Pharmaceutical company looks for buyers, contracts with Aspetuck to help.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- Embiosis Pharmaceuticals, Inc., has hired Aspetuck Capital Partners, Inc., a financial advisory firm specializing in life-science companies, to assist in the sale of the company. The company,...

Hot tips on bad bugs for better food.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- Discovering why some foods spoil and how bacteria survive heat treatments designed to preserve our produce is one step closer, according to Dutch scientists presenting their research at the Society for...

OPTIMA trial to compare antiretroviral treatment efficacy.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- The OPTIMA trial will provide a comprehensive comparison of antiretroviral treatment regimens. "OPTIMA (OPTions In Management with Antiretrovirals) is a clinical trial with a factorial...

Scientists describe germ warfare with gut bugs.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- Stuffing yourself with good bacteria could prevent repeat attacks from bugs responsible for ulcers and stomach upsets, according to scientists from the University of Reading. Food scientist Belinda...

Trichomonas vaginalis infections plague men visiting STD clinics.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- According to published research from the United States, "trichomonas is a cause of nongonococcal urethritis (NGU); however, studies of its prevalence in men have been hampered by the lack of sensitive...

Bacterial vaginosis may heighten the risk for acquiring herpes simplex virus-2.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- Bacterial vaginosis may heighten the risk for acquiring herpes simplex virus-2. "A longitudinal cohort study of sexually active women 18 - 30 years of age was conducted to identify variables...

Novel molecular assay provides rapid measure of S. aureus fluoroquinolone resistance.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- A novel polymerase chain reaction (PCR) assay provides a rapid and accurate measure of staphylococcal fluoroquinolone resistance. "Resistance to fluoroquinolones among clinical isolates of...

Oral acyclovir effective as neonatal varicella prophylaxis.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- Oral acyclovir can be used to prevent varicella infection in hospitalized newborns. "In December 2000, a female infant hospitalized in our Neonatal Care Centre was infected with varicella by her...

Mechanism of azole toxicity in Saccharomyces cerevisiae elucidated.
September 15, 2003... 2003 SEP 15 - (NewsRx.com & NewsRx.net) -- The mechanism of azole toxicity in Saccharomyces cerevisiae has been elucidated. "Fluconazole toxicity was previously shown to require intact mitochondria in Saccharomyces cerevisiae, however, the...