Anti-Infectives Week articles from November 2008

Anti-Infectives Week archives from November 2008

Research on cholera discussed by scientists at University of Tennessee.(Report)
November 3, 2008... "Vibrio cholerae is a gram-negative human intestinal pathogen that causes the diarrheal disease cholera. Humans acquire cholera by ingesting V. cholerae-contaminated food or water. Upon ingestion, V. cholerae encounters several barriers to...

Investigators at Duke University publish new data on drug resistance.
November 3, 2008... In this recent study, researchers in the United States conducted a study "To identify risk factors for surgical site infection (SSI) due to methicillin-resistant Staphylococcus aureus (MRSA). Prospective case-control study. One tertiary and 6...

New drug resistance findings from S. Harbarth and co-authors described.
November 3, 2008... According to recent research from Geneva, Switzerland, "We prospectively evaluated 46 possible risk factors for methicillin-resistant Staphylococcus aureus (MRSA) surgical site infection (SSI) among patients with MRSA carriage in a large...

New drug resistance study findings have been published by A.J. Peoples and colleagues.
November 3, 2008... According to recent research published in the Journal of Antibiotics, "Two novel antibiotics, neocitreamicins I and II, were isolated from a fermentation broth of a Nocardia strain." "This producing strain was obtained using an in situ...

New drug resistance study findings recently were published by I. Florescu and co-researchers.(Clinical report)
November 3, 2008... "Methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) are causing serious nosocomial infections. Tigecycline was evaluated in hospitalized patients with MRSA or VRE infection," scientists writing in the...

Recent studies by M.G. Fakih and co-authors add new data to hospital epidemiology findings.
November 3, 2008... In this recently published article, scientists in the United States conducted a study "To determine the effect of nurse-led multidisciplinary rounds on reducing the unnecessary use of urinary catheters (UCs). Quasi-experimental study with a...

Research results from A.L. Adler and colleagues update understanding of hospital epidemiology.
November 3, 2008... According to a study from the United States, "Varicella is highly contagious, and immunocompromised patients are at increased risk of severe illness, including disseminated disease, pneumonia, and encephalitis. We describe an outbreak of...

Studies conducted at Cincinnati Children's Hospital on brain and language recently published.
November 3, 2008... According to recent research from the United States, "Functional MRI was used to determine differences in patterns of cortical activation between children who suffered perinatal left middle cerebral artery (MCA) stroke and healthy children...

Researchers from St. Michael's Hospital discuss findings in infection control.(Survey)
November 3, 2008... According to recent research from Toronto, Canada, "Communicable respiratory illness is an important cause of morbidity among nurses. One of the key reasons for occupational transmission of this illness is the failure to implement appropriate...

Research conducted at Columbia University has provided new information about B-cell lymphoma.
November 10, 2008... "Overexpression of antiapoptotic members of the Bcl-2 family is observed in approximately 80% of B-cell lymphomas, contributing to intrinsic and acquired drug resistance. Nullifying the antiapoptotic influence of these proteins can potentially...

Investigators at University of Alberta target cirrhosis.
November 10, 2008... According to a study from Edmonton, Canada, " A human betaretrovirus has been characterized from patients with primary biliary cirrhosis (PBC). Uncontrolled studies using combination anti-retroviral therapy have reported significant biochemical...

BNC Collaborators Author High-profile Paper in Nature Nanotechnology.(Report)
November 10, 2008... Research by scientists collaborating with specialist product development consultancy, Bio Nano Consulting (BNC), into the workings of vancomycin - one of the few antibiotics that can be used to combat increasingly resistant infections such as...

New drug resistance findings from S. Stepanovic and co-authors described.(Report)
November 10, 2008... According to a study from Serbia, "The aim of this study was to explore the occurrence of methicillin-resistant staphylococci in a large urban public transport system. Samples were taken from hand rails, which passengers hold onto when they are...

New findings from University of East Anglia in the area of drug resistance described.
November 10, 2008... According to recent research from Norwich, the United Kingdom, "This paper presents the results of a meta-analysis of published transfer rates of antimicrobial resistance genes. A total of 34 papers were identified, of which 28 contained rates...

Investigators at University of Sao Paulo zero in on injury infection and critical care.(Report)
November 10, 2008... According to recent research published in the Journal of Trauma - Injury Infection and Critical Care, "Examination of the epidemiology and timing of trauma deaths has been deemed a useful method to evaluate the quality of trauma care. The...

Investigators at Wake Forest University release new data on injury infection and critical care.(Clinical report)
November 10, 2008... According to a study from the United States, "The administration of etomidate for rapid sequence induction (RSI) has been linked to subsequent adrenocortical insufficiency in nontrauma patients. However, etomidate-related adrenocortical...

New injury infection and critical care research from A.B. Nathens and co-researchers described.
November 10, 2008... According to recent research from Toronto, Canada, "Evaluation of trauma center performance has been limited to comparisons of observed versus expected mortality using trauma and injury severity score methodology. Few studies have focused on...

New injury infection and critical care study findings recently were published by researchers at University of Pennsylvania.
November 10, 2008... According to recent research published in the Journal of Trauma - Injury Infection and Critical Care, "The management of blunt solid organ injury (SOI) in children may differ depending on the treating facility. These differences, however, may...

Reports outline injury infection and critical care research from K. Ophelan and colleagues.
November 10, 2008... "Drug and alcohol use are common in neurotrauma patients. Despite growing methamphetamine use there are few studies of the impact of methamphetamine use on outcome after traumatic brain injury (TBI)," researchers in the United States report...

Reports outline injury infection and critical care study results from O.L. Gunter et al.(Report)
November 10, 2008... "Despite recent attention and impressive results with damage control resuscitation, the appropriate ratio of blood products to be transfused has yet to be defined. The purpose of this study was to evaluate whether suggested blood product ratios...

Reports summarize injury infection and critical care study results from M. Gomez and co-researchers.(Report)
November 10, 2008... "The purposes of this study were to determine current mortality predictors in our thermally injured population, to develop and validate a new mortality predictive score, and to compare its predictive ability with those of the acute physiology...

Research findings from J. Taller et al update understanding of injury infection and critical care.
November 10, 2008... According to a study from the United States, "Historically, penetrating injuries to the extremities account for up to 75% of wounds sustained during combat and 10% of deaths. Rapid vascular control and perfusion of injured extremities at...

Research from Virginia Commonwealth University in the area of injury infection and critical care described.
November 10, 2008... "Motor vehicle crashes (MVC) are the leading cause of maternal injury during pregnancy. It is estimated that 1,300 to 13,000 fetal deaths/yr result from maternal MVC," scientists in the United States report (see also Injury Infection and...

Studies from University of Leeds yield new information about injury infection and critical care.(Report)
November 10, 2008... "Recently, increasing emphasis is being placed upon assessment of the inflammatory status of the patient. Serum inflammatory cytokines, particularly IL-6, have been used as an adjunct to this assessment," scientists writing in the Journal of...

Investigators at Ohio State University publish new data on anti-infectives.
November 17, 2008... In this recently published article, scientists in the United States conducted a study "To describe any potential effect on in vitro susceptibility to imipenem for aerobic gram-negative bacteria following the addition of ertapenem to the...

Data on B-cell lymphoma described by C. Yang et al.
November 17, 2008... "Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma. Although some patients can be cured by current therapies, novel agents are needed to further improve outcomes," scientists in the United States report (see...

Research from N. Normanno and co-authors provides new data about breast cancer.
November 17, 2008... According to recent research from Naples, Italy, "Although the epidermal growth factor receptor (EGFR) is frequently expressed in human primary breast carcinoma, the majority of breast cancer patients do not respond to treatment with EGFR...

Research from F.K. Keter and co-authors in the area of cancer published.(Report)
November 17, 2008... According to recent research from Cape Town, South Africa, " Cisplatin (cis-diamminedichloroplatinum) was first identified for its anti-bacterial activity, and was later also shown to be an efficient anticancer agent. However, the therapeutic...

Study results from E. Topuz et al provide new insights into colon cancer.(Clinical report)
November 17, 2008... According to a study from Kayseri, Turkey, "In order to investigate the effect of kefir consumption on mucositis induced by 5-FU based chemotherapy (CT), we monitored the systemic immune response by measurement of the serum proinflammatory...

Recent findings from A. Rebbaa and co-authors highlight research in angiogenesis.
November 24, 2008... "Previous studies from our laboratory have demonstrated that thyroid hormones play a key role in cancer progression. In addition, a deaminated form, tetraiodothyroacetic acid (tetrac), that antagonizes the proliferative action of these hormones...

Study findings from Haverford College broaden understanding of cholera.
November 24, 2008... "Vibrio cholerae O1 from a 2006 outbreak in Accra were commonly resistant to multiple antimicrobials and, in particular, to trimethoprim/sulfamethoxazole, drugs commonly used in the treatment of cholera. We sought to determine the genetic basis...

New Study Shows Subglottic Secretions Drainage Reduces Ventilator Associated Pneumonia and Antibiotic Use.(Clinical report)
November 24, 2008... A two-year randomized study just published in the peer-reviewed journal CHEST (November 2008) demonstrates that continuous aspiration of subglottic secretions (CASS)(1) significantly reduced antibiotic usage in post-cardiac surgery patients....

Reports outline DNA research study findings from University of Texas.
November 24, 2008... According to recent research from the United States, "The Mre11-Rad50-Nbs1 complex and autophosphorylated Ser(1981)-ATM are involved in recognizing and repairing DNA damage, such as double-strand breaks (DSB). However, the role of these factors...

New drug resistance data have been reported by scientists at Federal University.(Report)
November 24, 2008... According to a study from Brazil, "The increasing problems with multidrug resistance in relation to Corynebacterium, including C. diphtheriae, are examples of challenges confronting many countries. For this reason, Brazilian C. diphtheriae...