Anti-Infectives Week articles from May 2004

Anti-Infectives Week archives from May 2004

Suprax launched in the U.S.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Lupin, Ltd., has now launched its anti-infective product Suprax (cefixime Oral Suspension) in the U.S. The newly established, 50-strong, pediatric-specialty sales force of the company's subsidiary,...

Novel antibacterial agents for skin infections reviewed.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Researchers review novel antibacterial agents for skin and skin structure infections in a recent issue of the Journal of the American Academy of Dermatology. "With the continuing development of...

Optimizing antibacterial therapy for respiratory infections described.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Researchers outline the optimization of antibacterial therapy for community-acquired respiratory tract infections in children in an era of bacterial resistance. "The spread of antibacterial...

Amoebae-resisting bacteria isolated from amoebal coculture.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- New amoebae-resisting bacteria species may be isolated from heavily contaminated samples using amoebal coculture. "Amoebae feed on bacteria, and few bacteria can resist their microbicidal ability....

Pneumococcal vaccine not useful in HIV patients responding to HAART.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- The 23-valent pneumococcal vaccine does not offer additional protection against pneumonia in HIV-infected patients who have an immunological response to highly active antiretroviral therapy (HAART). ...

Varible Etest TB drug resistance results cause concern.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Discrepancies between Etest and other assays of tuberculosis drug resistance have been reported. In a recent study from Brazil, M. tuberculosis strains "resistant to streptomycin (SM), isoniazid...

AACR data indicate strong synergy of Hsp90 inhibitor, 17-AAG.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Kosan Biosciences (KOSN) announced, at the American Association for Cancer Research, preclinical in vitro data on the cytotoxic and antiproliferative effects of Kosan's lead Hsp90 inhibitor, 17-AAG,...

CLEAR II registry launched.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Enzon Pharmaceuticals, Inc., (ENZN) announced a major new initiative to build upon the value of its CLEAR (Collaborative Exchange of Antifungal Research) patient registry with the launch of CLEAR II....

Plasmodium falciparum drug resistance in India determined.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- The prevalence and patterns of Plasmodium falciparum drug resistance in India have been characterized. In a recent study, the P. falciparum "chloroquine resistance transporter (Pfcrt) K76T mutation...

Microbes that produce hydrogen peroxide reduce obstetrical complications.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Microbes that produce hydrogen peroxide reduce obstetrical complications. According to recent research published in the Journal of Clinical Microbiology, "lactobacilli, principally the strains that...

PhotoPoint company reports progress during 2003, including lower net loss.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Miravant Medical Technologies (MRVT), a pharmaceutical development company specializing in PhotoPoint photodynamic therapy (PDT), announced consolidated financial results for the fourth quarter and the...

Studies support Targretin's activity in NSCLC.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Three separate studies by Ligand Pharmaceuticals, Inc., (LGND) scientists presented at the 95th annual meeting of the American Association of Cancer Research (AACR) support enhanced activity of...

P-glycoprotein-derived peptides inhibited multidrug resistance of tumors.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Immunization with synthetic P-glycoprotein-derived peptides inhibited multidrug resistance of tumors. "Overexpression of the membrane glycoprotein (P170) represents the most common multidrug...

Italian government places $1.1 million initial order for SR-1.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- TVI Corp. (TVIN), a supplier of rapid-deployment shelters and chemical/biological decontamination systems for the military, public health, and first response agencies, announced that the Italian Civil...

SkinRenu Plus maker announces worldwide launch of its products.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- HealthRenu Medical, Inc., (HRUM.OB) is currently in talks with key healthcare distributors to distribute its products in the United States, Europe, the Middle East, and Asia. The company expects to...

Plasmodium vivax vivapains characterized.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- The structural and functional properties of vivapains - putative enzymatic targets for antimalarial agents - have been elucidated. "Cysteine proteases play important roles in the life cycles of...

Novel assay provides improved measure of plasmodial Plm II activity.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- A novel assay provides an improved measure of a key plasmodial enzyme. "The emergence and worldwide spreading of Plasmodium falciparum strains that have shown to be resistant to traditional drugs...

Novel ribonuclease has antimicrobial and antiproliferative activities.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- A novel ribonuclease derived from an edible mushroom has demonstrated antimicrobial, antifungal and antitumor activities. In a recent study from China, a "12 kDa ribonuclease preferential for poly...

Novel sesquiterpene lactones show promise as antimalarial agents.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- A series of novel lactones with potent antimalarial activity have been developed. According to researchers in Germany, "[f]our sesquiterpene lactones of the pseudo-guaianolide type (helenalin,...

Pyrrole BM212 derivatives have improved antimycobacterial activity.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Pyrrole BM212 derivatives have demonstrated improved antimycobacterial activity over their parent compound. In a recent study, researchers in Italy "identified BM212 as a lead compound among a...

QSAR analysis on anti-HIV HEPT analogues described.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- A QSAR analysis of putative antiretroviral HEPT analogues has been described. According to published research from India, a "Quantitative Structure-Activity Relationship (QSAR) study has been...

Pyrrolopyrimidine a novel and selective MRP1 inhibitor.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- A pyrrolopyrimidine is shown to be a novel and selective multidrug-resistance-associated protein 1 inhibitor. "Multidrug resistance mediated by P-glycoprotein (Pgp) or...

Multilocus sequence Staphylococcus epidermidis typing effective.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Multilocus sequence typing (MLST) can facilitate the epidemiological study of Staphylococcus epidermidis. S. epidermidis is a significant cause of nosocomial disease," scientists in New Jersey...

Recombinant AAV-2 useful as anti-HIV RNAi vector.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Recombinant AAV-2 is suitable for use as an anti-HIV RNAi vector. According to recent research from Rhode Island, the "cellular introduction of short, interfering RNA leads to sequence-specific...

HAART-induced recovery of HIV-specific immunity described.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- The recovery of HIV-specific immune activity in HAART-treated patients has been elucidated. According to recent research from Canada, the "extent to which highly active antiretroviral therapy...

Dapsone-induced hypersensitivity pneumonitis can mimic PCP.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Hypersensitivity pneumonitis triggered by dapsone exposure can emulate PCP in HIV/AIDS patients. "Interstitial pneumonitis, often related to infectious etiologies, occurs commonly in HIV-infected...

Essential eukaryotic core identified from P. carinii.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Genetic data from Pneumocystis carinii has been used to elucidate the essential eukaryotic core. According to researchers in the United States, P. carinii, an "AIDS-related fungal pathogen," is...

Visceral leishmaniasis relapse common during ineffective HAART.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Relapse of visceral leishmaniasis (VL) is common in HIV patients with a weak response to HAART. According to recent research from Spain, there are "contradictory data about whether highly active...

Antiretroviral therapy does not prevent contingent negative variation.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Antiretroviral treatment does not prevent contingent negative variation abnormalities in HIV patients. In a recent study from California, the "contingent negative variation, an event-related...

Cessation of CMV retinitis therapy has no long-term sequelae for HIV patients.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Cessation of successful CMV retinitis therapy has no long-term sequelae for HIV patients. "Potent antiretroviral therapy stimulates robust and durable immune reconstitution among profoundly...

Dose escalation unnecessary in patients switching to nevirapine from efavirenz.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Dose escalation in not necessary when switching HIV patients to nevirapine from efavirenz treatment. "Efavirenz induces the metabolism of co-administered drugs through the induction of CYP 3A4,"...

Early IL-2 treatment increases CD4 cell count in HIV patients.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Exogenous IL-2 therapy can augment CD4 cell counts in HIV patients undergoing antiretroviral treatment. "Early treatment intervention during human immunodeficiency virus (HIV) infection is a...

In utero AZT exposure has little or no impact on neurodevelopment.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Exposure to the antiretroviral agent azidothymidine (AZT) in utero does not have a significant impact on neurodevelopment. AZT is "administered to pregnant women with HIV to prevent the spread of...

Indinavir superior to ritonavir and saquinavir in triple therapies.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Indinavir is superior to ritonavir and saquinavir as a component of triple antiretroviral regimens. According to a recent study from Spain, the "introduction of the so-called highly active...

Indinavir/ritonavir/efavirenz regimen should benefit treatment-naive patients.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Treatment-naive HIV patients should respond well to a regimen of indinavir and ritonavir at standard dose levels with efavirenz. According to published research from the Netherlands, a...

Pre-HAART IL-7 levels linked to long-term CD4 cell count.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Interleukin (IL)-7 levels prior to HAART initiation are correlated with long-term CD4 cell recovery. "Highly active antiretroviral therapy (HAART) in HIV patients generally increases the CD4 cell...

Surgery can benefit patients with antiretroviral-induced "buffalo hump".
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Surgical intervention is feasible for treatment-induced "buffalo humps" in HIV patients. "Fat redistribution disorders are common complications of antiretroviral therapy," explained C. Gervasoni...

Antimicrobial technology granted EPA registration.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- A pioneering antimicrobial technology from Engelhard Corporation (EC) has been granted registration by the U.S. Environmental Protection Agency (EPA) for use against tuberculosis, HIV and many other...

More hospitals offering private rooms and reducing nosocomial infection.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- A day after suffering a heart attack, Bob McAuliffe was resting comfortably in Bronson Methodist Hospital, one of a growing number of new or renovated hospitals in Michigan and throughout the United...

Nonculturable bacteria thrive in the human urinary tract.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Nonculturable bacteria thrive in the human urinary tract. According to recent research published in the Journal of Clinical Microbiology, "the presence of viable but nonculturable bacteria in human...

Handrub promotion extremely cost-effective.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- The cost of promoting hand hygiene in hospitals is far lower than the cost of infectious outbreaks. In a recent study, scientists in Switzerland "evaluated the costs associated with a sustained and...

Oncogenesis from single base mutation in IRES of Epstein-Barr nuclear antigen 1.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Oncogenesis develops from a single base mutation in the internal ribosome entry site of Epstein-Barr nuclear antigen 1. Recently published data show that "the U leader exon located within the 5'...

Preventive practices eliminate the risk for congenital toxoplasmosis.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Preventative practices eliminate the risk for congenital toxoplasmosis. "Congenital toxoplasmosis in humans is due to the infection of the fetus by Toxoplasma gondii (a protozoan parasite of...

U.S. patent filed for anti-sepsis compound.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- CytoGenix, Inc., (CYGX) announced the filing of a patent application with the U.S. Patent and Trademark Office for an invention titled Oligodeoxynucleotide Intervention for Prevention and Treatment of...

Patient enrollment begins for phase III study of PeriostatMR.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- CollaGenex Pharmaceuticals, Inc., (CGPI) announced that it has initiated patient screening and enrollment of a multicenter, double-blinded, placebo-controlled phase III clinical study to evaluate the...

Detlef Albrecht, MD, named chief medical officer of biopharma company.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- IntraBiotics Pharmaceuticals, Inc., (IBPI) announced the appointment of Detlef Albrecht, MD, to the position of senior vice president of preclinical and clinical research and development and chief...

Up-regulation of ubiquitin-specific protease enhances EBV proliferation in vitro.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Up-regulation of ubiquitin-specific protease enhances Epstein-Barr virus proliferation in vitro. "The family of ubiquitin (Ub)-specific proteases (USP) removes Ub from Ub conjugates and regulates a...

Nedd 4 or ubiquitin ligase Nedd4 regulates human T-cell leukemia virus type 1.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Nedd 4 or ubiquitin ligase Nedd4 regulates human T-cell leukemia virus type 1. "The Gag protein of human T-cell leukemia virus type 1 (HTLV-1) contains the conserved sequences PPxY and PTAP, which...

Antioxidant levels are low during active TB, but rise during treatment.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Antioxidant levels are reduced in patients with active tuberculosis, and rise during effective therapy. "In tuberculosis, oxidative stress is a result of tissue inflammation, poor dietary intake of...

Broth microdilution with 7H9 broth suitable as TB drug resistance test.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Broth microdilution using 7H9 provides an accurate measure of Mycobacterium tuberculosis drug resistance. In a recent study, scientists in Turkey "evaluated the broth microdilution method (BMM) for...

Bovine herpesvirus 4 persistently infects neuronal cells in vitro.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Bovine herpesvirus 4 persistently infects neuronal cells in vitro. "Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus with no clear disease association. Although BoHV-4 is not considered a...

Marine sponge constituent cribrostatin 6 bactericidal against S. pneumoniae.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- The marine sponge constituent cribrostatin 6 is bactericidal against S. pneumoniae. "The antibacterial activity of the nitrogen heterocyclic sponge constituent cribrostatin 6 was examined....

In vivo expression technology identifies virulence genes in H. pylori.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- In vivo expression technology identifies virulence genes in H. pylori. "Some pathogenic factors of Helicobacter pylori, a bacterium involved in peptic ulcer and gastric cancer, have already been...

Sodium selenite has potent antimalarial activity.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- A novel selenium compound has demonstrated potent antimalarial activity. In a recent study from Japan, the "in vitro antimalarial activity of sodium selenite (NaSe) was investigated and the...

Daptomycin useful for treating drug-resistant Gram-positive pathogens.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Daptomycin is a novel agent for treating infections due to drug-resistant Gram-positive pathogens. According to recent research from the United States, "Daptomycin is a novel cyclic lipopeptide...

Company files patent application for MDI-P for sepsis.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Medical Discoveries, Inc., (MLSC) (MDI) announced that it has filed a provisional patent application on sepsis for MDI-P, its proprietary drug, as of March 17, 2004. The patent application was...

Second-generation triazoles highly effective against opportunistic fungi.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Second-generation triazole antibiotics have demonstrated potent antifungal activity in vitro. In a recent study, researchers in the United States "examined the in vitro activities of voriconazole,...

Small molecule inhibitors found active against anthrax lethal factor.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Small molecule inhibitors are found to be active against anthrax lethal factor in vitro. "The virulent spore-forming bacterium Bacillus anthracis secretes anthrax toxin composed of protective...

Genome Therapeutics changes name after merger.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Genome Therapeutics Corp. (GENE), following the merger with Genesoft Pharmaceuticals and to better reflect its focus on drug development and commercialization, has received shareholder approval to...

Novel assay improves early detection of ESBL-producing organisms.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- A novel assay enables rapid identification of drug-resistant ESBL-producing pathogens. Researchers in Israel conducted a study "to evaluate an accelerated protocol for the early detection of...

Aaptamine derivatives show antitumor and antimicroibal activity.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- A pair of aaptamine-derived salts have demonstrated significant antitumor and antimicrobial activity. According to published research from the United States, the "marine sponge constituent...

HIV integrase pharmacophore model developed.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- A novel HIV-1 integrase (HIV-IN) pharmacophore model has been developed and validated. According to recent research from the United States, this "three-dimensional pharmacophore model" was...

Novel PNU-100480 analogues have antimycobacterial activity.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- A series of PNU-100480 analogues have demonstrated antimycobacterial activity. As part of a "search program for new antitubercular drugs," scientists in Italy examined the "potentiality of...

Novel endoperoxide antimalarial agents synthesized.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- A number of endoperoxide antimalarial agents have been synthesized. Researchers in Australia described the "synthesis of a series of novel epoxy endoperoxide compounds that can be prepared in high...

Peroxyketal function key to activity of G factor-derived antimalarials.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Peroxyketal function plays a key role in the activity of G factor-derived antimalarial agents. In a recent study from France, "[n]ew endoperoxides, related to the natural phytohormones known as G...

Thiophene-containing nelfinavir analog synthesized.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- The first thiophene-containing analog of the antiretroviral agent nelfinavir has been synthesized. C. Bonini and colleagues at the University of Basilicata in Potenza, Italy developed a...

Zanamivir derivatives show improved anti-influenza activity.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- A series of zanamivir derivatives have shown improved antiviral activity compared to their parent compound. According to published research from Australia, a "set of trimeric and tetrameric...

HIV gp120 mutations linked to BMS-806 and #155 resistance identified.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Mutations in the HIV gp120 coat protein have been identified that confer resistance to a pair of promising antiretroviral agents. "BMS-806 and the related compound, #155, are novel inhibitors of...

TMP-SMZ therapy does not select for S. aureus small colony variants.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Surprisingly, TMP-SMZ treatment does not increase the risk of Staphylococcus aureus small colony variant (SCV) infection in HIV patients. Emergence of S. aureus SCVs "has been associated with...

Antiretroviral agents may be useful for SARS prevention and treatment.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Antiretroviral agents may be useful for SARS prevention and/or therapy. In a recent study, scientists in China "observed that 0 of 19 patients with human immunodeficiency virus type 1 (HIV-1)...

Gender-based variations in saquinavir pharmacology identified.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Gender-based variations in saquinavir pharmacokinetics and efficacy have been identified. "AIDS Clinical Trials Group study 359 was a controlled study of saquinavir with either ritonavir or...

HAART restores T-cell repertoire in patients with acute HIV infection.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- HAART restores T-cell repertoires in patients with acute - but not chronic - HIV infection. "In drug-naive HIV+ patients," scientists in Italy "analyzed the effects of highly active antiretroviral...

Metabolic effects of lopinavir-ritonavir regimens evaluated.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- The metabolic effects of lopinavir-ritonavir antiretroviral regimens have been characterized. In a study from Spain, the "evolution of fasting glucose, triglyceride, and total and high-density...

Tenofovir-associated renal tubular dysfunction described.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Renal tubular dysfunction associated with tenofovir treatment has been characterized. Scientists in France described "seven cases of renal tubular injury in HIV-infected patients receiving an...

Terpenes can improve transdermal zidovudine delivery.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Terpenes can be used to enhance the transdermal delivery of the anti-HIV agent AZT in a murine model. In a recent study from India, the "effect of various oxygen-containing monoterpenes such as...

APIC initiative to address low flu-shot rate among healthcare workers.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- The Association for Professionals in Infection Control and Epidemiology (APIC) announced a new national initiative to improve influenza immunization rates among healthcare workers. APIC is a...

GENE-TRAK Listeria Microwell Test receives AOAC validation.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Neogen Corp. (NEOG) announced that it has received Performance Tested Method status from the AOAC Research Institute for its newest rapid test to detect Listeria. According to the company, the...

Plasmodium yoelii mdr1 gene from artemisinin-resistant line characterized.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- The mdr1 gene from an artemisinin-resistant strain of the murine malarial pathogen Plasmodium yoelii has been characterized. "The molecular mechanisms by which the malarial parasite has managed to...

Evolution of drug-resistant P. falciparum in eastern Sudan characterized.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- The development of plasmodial drug resistance has been characterized in a region of seasonal malaria transmission. In a recent study, scientists in Sudan "investigated the evolution of...

Promoter activity of AVL-A LTR region related to induction of glial neoplasm.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- The promoter activity of the avian leukosis virus subgroup A LTR region may be related to the induction of glial neoplasm. "So-called fowl glioma is a retroviral infectious disease caused by avian...

Common intestinal parasites reviewed.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Researchers have reviewed common intestinal parasites in a recent issue of the journal American Family Physician. According to research from the United States, "Intestinal parasites cause...

Interferon-alpha inhibits SARS coronavirus.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Interferon-alpha has a significant inhibitory effect on the virus responsible for SARS. According to recent research from Canada, "[c]urrent treatment schemes for severe acute respiratory syndrome...

Topical amphotericin B licensed to Accentia.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- BioDelivery Sciences International, Inc., (BDSI; BDSIW) announced that it has licensed a topical formulation of its lead product, encochleated amphotericin B to Accentia, Inc. Accentia, Inc., a...

Post-SCT antimicrobial treatment practices evaluated.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Antimicrobial treatment policies have been evaluated in a number of stem-cell transplant centers. "Antimicrobial agents are commonly used after hematopoietic stem cell transplant (HSCT) to prevent...