Anti-Infectives Week articles from June 2009

Anti-Infectives Week archives from June 2009

New acute myeloid leukemia data have been reported by researchers at Korea University.
June 1, 2009... According to a study from Seoul, South Korea, "Resistance to cytarabine (Ara-C) incapacitates the therapeutic effort during the treatment of acute myeloid leukemia (AML). To elucidate mechanism responsible for the development of resistance to...

Findings from University of Duisburg-Essen advance knowledge in antimicrobials.
June 1, 2009... "Plants in more than 300 genera produce extrafloral nectar (EFN) to attract carnivores as a means of indirect defence against herbivores. As EFN is secreted at nectaries that are not physically protected from the environment, and contains...

Studies from University of Nigeria provide new data on antiretrovirals.(Report)
June 1, 2009... According to recent research published in the journal Health Policy and Planning, "The anti-retroviral (ARV) treatment programme in Nigeria is delivered through selected teaching and mission hospitals at a free/subsidized rate. The government...

New breast cancer data have been reported by scientists at Central South University.(Report)
June 1, 2009... " Chemotherapy is not only important but also necessary for the patient of breast cancer. Breast cancer resistance protein (BCRP), an atypical drug efflux pump, mediates multidrug resistance in breast cancer," scientists in Changsha, People's...

Studies from V. Andersen et al provide new data on colon cancer.
June 1, 2009... "Smoking, dietary factors, and alcohol consumption are known life style factors contributing to gastrointestinal carcinogenesis. Genetic variations in carcinogen handling may affect cancer risk," scientists writing in the journal BMC Medical...

New infection control study findings have been reported by P. Lecat and co-researchers.(Report)
June 1, 2009... According to recent research from the United States, "Approximately 1 in 20 hospital admissions is complicated by a health care-associated infection. Stethoscopes may play a role in spreading nosocomial infections." "The objective of this...

Research from University of Gaziantep yields new data on infection control.
June 1, 2009... "The selection of medical textiles is an important subject for the health care sector in terms of benefits and costs. The basic cost calculation does not always yield to proper results in product selection; it would even mislead," scientists in...

Studies conducted at University of Helsinki on infection control recently published.
June 1, 2009... According to a study from Helsinki, Finland, "We estimated the burden of health care-associated infections (HAIs) occurring in Finnish adult acute care hospitals using national hospitalization data and estimates of HAI based on a recent...

Studies from Chang-Gung University provide new data on infection control.(Report)
June 1, 2009... According to recent research from Taiwan, "Bioaerosols from numerous sources have been implicated in respiratory diseases. This study evaluated the characteristics and weekly variations in indoor air in a medical intensive care unit (ICU) in...

Studies in the area of infection control reported from Mahidol University, Medical Department.
June 1, 2009... According to recent research from Bangkok, Thailand, "Surgical site infections have been caused by gentian violet (GV) marking solutions that were contaminated with Mycobaterium chelonae. GV solution is also used in surgery to mark surgical...

Study results from M. Sautour and colleagues in the area of infection control published.
June 1, 2009... "Invasive filamentous fungi infections resulting from inhalation of mold conidia pose a major threat in immunocompromised patients. The diagnosis is based on direct smears, cultural symptoms. and culturing fungi," scientists writing in the...

Data on injury infection and critical care described by H.E. Finlaymorreale et al.(Report)
June 1, 2009... According to recent research published in the Journal of Trauma - Injury Infection and Critical Care, "Accurate data regarding intimate partner violence is difficult to obtain, particularly when examining only homicides or trauma registries....

New data from C. Probst et al illuminate research in injury infection and critical care.
June 1, 2009... According to a study from Hannover, Germany, "The information about the long-term mortality and causes of death after multiple injuries is sparse. In general, most follow-up studies report on 1 year to 3 years maximum follow up." "The...

New findings from S.C. Nessen and co-authors describe advances in injury infection and critical care.
June 1, 2009... According to recent research published in the Journal of Trauma - Injury Infection and Critical Care, "United States Army Forward Surgical Teams (FSTs) consits of twenty personnel and are the Army's smallest surgical units. Currently, they...

New injury infection and critical care data have been reported by D. Gomez and co-authors.
June 1, 2009... According to recent research from Toronto, Canada, "If there are systematic differences in the types of patients captured in registries, then differences in outcomes in centers might be related not to differences in the practice of care, but...

New injury infection and critical care data have been reported by P. Hadjizacharia and co-authors.
June 1, 2009... "Physical assault is common in trauma patients. Penetrating injuries resulting from interpersonal violence have been well described in literature, but there have been few studies examining the injury patterns due to assaults with hands and feet...

New injury infection and critical care research from University of Hong Kong outlined.
June 1, 2009... According to recent research published in the Journal of Trauma - Injury Infection and Critical Care, "Traffic safety of the elderly is a growing public health issue. This study makes use of a linked hospital and police database." "A total...

New research on injury infection and critical care from P. Weninger and co-authors summarized.
June 1, 2009... According to a study from Vienna, Austria, "Interlocking nailing is a standard procedure in the surgical treatment of tibial fractures. Despite it has been described to be a safe technique with excellent functional results compared with...

Recent findings in injury infection and critical care described by researchers from Radboud University.(Clinical report)
June 1, 2009... "Discussion still remains whether computed tomography (CT) of the abdomen, pelvis, and lumbar spine should be performed routinely after blunt trauma with high energy impact or only in restricted situations. The purpose of this study was to...

Report summarizes injury infection and critical care study findings from Y.B. Unver and co-researchers.(Report)
June 1, 2009... In this recently published study, investigators in Istanbul, Turkey conducted a study "To determine the value of calculating an ocular trauma score (OTS) for patients with open-globe injuries. OTS evaluating system can provide valuable...

Reports from Army describe recent advances in injury infection and critical care.
June 1, 2009... "Analysis of the epidemiology and attribution of in-hospital deaths is a critical component of learning and process improvement for any trauma center. We sought to perform a detailed analysis of in-hospital deaths at a combat support hospital,"...

Reports from I.R. Diamond and co-researchers add new data to research in injury infection and critical care.(Report)
June 1, 2009... "Previously, we demonstrated that 21% of pediatric( "This study aims to examine the current preventable trauma death rate in our system using identical methodology to our previous study. The records of all children (< 16 years) who died in...

Reports from K.V. Brown and co-researchers add new data to research in injury infection and critical care.(Report)
June 1, 2009... According to recent research from Birmingham, the United Kingdom, "Despite modern advances, amputation is still a commonly performed operation in war. It is often difficult to decide whether to amputate after high-energy trauma to the lower...

Reports outline injury infection and critical care study findings from S. Deppe and colleagues.(Clinical report)
June 1, 2009... According to recent research published in the Journal of Trauma - Injury Infection and Critical Care, "Hospital accounting methods use diagnosis-related group (DRG) data to identify patients and derive financial analyses and reports. The...

Reports outline injury infection and critical care study results from University of Rochester.
June 1, 2009... According to a study from the United States, "The use of prosthetic grafts for reconstruction of military vascular trauma has been consistently discouraged. In the current conflict, however, the signature wound involves multiple extremities...

Research from Yale University, Medical Department provides new data about injury infection and critical care.(Report)
June 1, 2009... "This study assesses if a physicochemical (PC) approach to acid-base balance improves the accuracy of acid-base diagnosis, and reduces inappropriate fluid loading. Hundred consecutive patients with trauma admitted to a surgical intensive care...

Researchers from Army detail findings in injury infection and critical care.
June 1, 2009... According to recent research published in the Journal of Trauma - Injury Infection and Critical Care, "We hypothesized that the number of evacuated casualties from a combat-related multiple casualty event provides an initial baseline estimate...

Researchers from Army provide details of new studies and findings in the area of injury infection and critical care.
June 1, 2009... "Infections are a common acute and chronic complication of combat-related injuries; however, no systematic attempt to assess infections associated with US combat-related injuries occurring in Iraq and Afghanistan has been conducted. The Joint...

Scientists at Far Eastern Memorial Hospital discuss research in injury infection and critical care.
June 1, 2009... "Muscles used for patellar and peripatellar soft tissue construction, which include the vastus medialis, vastus lateralis, gastrocnemius, and sartorius muscle, are often clinically inadequate for reconstruction of the patellar and peripatellar...

Scientists at Rush University publish new data on injury infection and critical care.
June 1, 2009... "Fractures of the proximal and distal one thirds of the tibial shaft have historically higher malunion rates than those of the midshaft. This retrospective case series evaluates the postoperative radiographic outcome of intramedullary nailing...

Studies from Harvard University provide new data on injury infection and critical care.(Report)
June 1, 2009... "Prehospital management of exsanguinating extremity injuries (EEI) includes direct compression or tourniquets or both. Direct compression may be ineffective in deep wounds and requires a person committed to compressing," scientists in the...

Studies from J.V. Oconnor and colleagues yield new information about injury infection and critical care.
June 1, 2009... According to a study from the United States, "Pulmonary contusions (PCs) are a common injury sustained in motor vehicle collisions. The crash and occupant characteristics of PC in motor vehicle collisions are currently unknown." ...

Study data from R.J. Gaines et al provide new insights into injury infection and critical care.(Report)
June 1, 2009... According to recent research from the United States, "The cause of posttraumatic arthritis in Lisfranc injuries is argued in the literature. The purpose of this study was to determine whether the involved joint surface area increased with...

USA Scientific publishes research in injury infection and critical care.(Report)
June 1, 2009... "The mechanisms of modern warfare unfortunately have lead to many ocular injuries. This study attempts to quantify the effect of military combat eye protection on the incidence of ocular injury among US service members engaged in current combat...

Scientists at Washington University publish research in apoptosis.
June 8, 2009... According to a study from the United States, "In spite of compelling evidence-implicating caspases in drug-induced apoptosis, how tumors modulate caspase expression and activity to overcome the cytotoxicity of anticancer agents is not fully...

Studies from National Taiwan University provide new data on breast cancer.(Report)
June 8, 2009... "Connective tissue growth factor (CTGF) expression is elevated in advanced breast cancer and promotes metastasis. Chemotherapy response is only transient in most metastatic diseases," investigators in Taipei, Taiwan report (see also Breast...

Data on drug resistance reported by researchers at Wroclaw University.
June 8, 2009... "Using the whole-cell patch-clamp technique, the influence of selected multidrug resistance modulators, both plant-derived compounds and derivatives on the activity of voltage-gated potassium channels Kv1.3 was investigated. Twelve compounds...

Findings from C.S. Enwemeka and co-authors provide new insights into drug resistance.
June 8, 2009... According to recent research from the United States, "In a previous study, we showed that 405-nm light photo-destroys methicillin-resistant Staphylococcus aureus (MRSA). The 390-420 nm spectral width of the 405-nm superluminous diode (SLD)...

Findings from Hospital for Sick Children advance knowledge in drug resistance.
June 8, 2009... "Multidrug transporters such as the small multidrug resistance (SMR) family of bacterial integral membrane proteins are capable of conferring clinically significant resistance to a variety of common therapeutics. As antiporter proteins of...

Research from University of California broadens understanding of behavior.
June 15, 2009... "Multidrug efflux transporters, especially those that belong to the resistance-nodulation-division (RND) family, often show very broad substrate specificity and play a major role both in the intrinsic antibiotic resistance and, with increased...

Research data from Z.X. Du and colleagues update understanding of cancer.
June 15, 2009... According to recent research from Shenyang, People's Republic of China, "The proteasome inhibitor bortezomib has shown impressive clinical activity alone and in combination with conventional and other novel agents for the treatment of multiple...

Research from University of Alabama yields new findings on colitis.
June 15, 2009... "P-glycoprotein (P-gp), the product of the multidrug resistance gene (MDR), is an ATP-dependent transmembrane pump. which is expressed in multiple cell lineages including epithelial and hematopoetic cells. The human MDR gene is located on...

Data on drug resistance described by researchers at University of Missouri.
June 15, 2009... According to recent research published in the Journal of Ocular Pharmacology and Therapeutics, "The purpose of this manuscript is to investigate the presence of nucleoside/nucleotide efflux transporter in cornea and to evaluate the role in...

Data on drug resistance published by researchers at University Hospital.
June 15, 2009... "Because the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) differs among the 3 countries forming the Euregio Meuse-Rhin (EMR) region (Belgium, Germany, and the Netherlands), cross-border healthcare requires information about...

Studies from S.V. Klymenko and co-researchers yield new data on acute myeloid leukemia.
June 22, 2009... "We report on the results of multidrug-resistance transporters (P-glycoprotein, LRP, and MDR1), and apoptosis-related proteins (Fas, Bcl-2, Bax, p53, and Bcl-X-L) expression analysis of 56 acute myeloid leukemia (AML) patients by flow...

Researchers from Keio University detail findings in breast cancer.
June 22, 2009... "It has been previously shown that gefitinib reverses breast cancer resistance protein (BCRP)mediated drug resistance. Here, the impact of BCRP on gefitinib-mediated inhibition in epidermal growth factor receptor (EGFR) signaling is evaluated,"...

New diagnostics study results reported from D.S. Perlin et al.
June 22, 2009... "Invasive aspergillosis remains difficult to diagnose despite advances in imaging and antigen-based serological testing. To overcome this problem, nucleic acid (NA)-based amplification assays were introduced to identify infecting pathogens,"...

New drug resistance study findings have been published by scientists at University of North Carolina.
June 22, 2009... According to recent research from the United States, "To test the ability of nanoparticle formulations to overcome P-glycoprotein (P-gp)-mediated multidrug resistance, several different doxorubicin and paclitaxel-loaded lipid nano-particles...

New findings from S. Chang and co-researchers in the area of drug resistance described.(Clinical report)
June 22, 2009... 'In a prospective study involving 115 patients with methicillin-resistant Staphylococcus aureus nares carriage, we found that skin and environmental contamination with methicillin-resistant S. aureus was as likely among individuals whose S....

Study findings on anti-infectives are outlined in reports from University of Udine.(Report)
June 29, 2009... According to recent research from Udine, Italy, "The efficacy of vancomycin against methicillin-resistant Staphylococcus aureus (MRSA)-related infections has been called into question by recent findings of higher rates of failure of vancomycin...

Data from F. Tatari and colleagues advance knowledge in breast cancer.
June 29, 2009... "The human multidrug resistance gene 1 (MDR1) encodes a plasma membrane, P-glycoprotein (Pgp), which functions as the transmembrane efflux pump for various structurally unrelated anticancer agents and toxins. Polymorphisms in the MDR1 gene may...

New drug resistance data have been reported by N. Willand and co-authors.
June 29, 2009... According to recent research from Lille, France, "The side effects associated with tuberculosis therapy bring with them the risk of noncompliance and subsequent drug resistance. Increasing the therapeutic index of antituberculosis drugs should...

New drug resistance research has been reported by M.M. Traczewski et al.
June 29, 2009... According to a study from the United States, "The inhibitory and bactericidal activities of daptomycin, vancomycin, and teicoplanin against a collection of 479 methicillin-resistant Staphylococcus aureus isolates were assessed. The isolates...

Reports by J. Aragonsanchez and co-researchers describe recent advances in drug resistance.(Report)
June 29, 2009... "The aim of this study was to compare the outcomes of surgical treatment of osteomyelitis caused by methicillin-resistant Staphylococcus aureus (MRSA) with cases caused by methicillin-sensitive Staphylococcus aureus (MSSA). We abstracted data...

New burn care research from University of Zurich described.(Report)
June 29, 2009... "The aim of this study was to provide an increased level of evidence on surgical management of high-tension electrical injuries compared with thermal burns using a case-controlled study design. Sixty-eight patients (64 males, 4 females, aged...

New findings from F. Uygur and co-researchers in the area of burn care research described.
June 29, 2009... According to recent research from Turkey, "The factors and demographic features of self-inflicted burns in Eastern and Western cultures differ from each other. In this retrospective study, the authors' aim is to identify the epidemiologic...

New findings reported from L.G. Schnell and co-authors describe advances in burn care research.
June 29, 2009... According to a study from the United States, "Marjolin's ulcers, or malignancy originating from burn scars, have been recorded in the literature since the first century AD (Ozek et at. Marjolin's ulcers arising in burn scars." "J Burn Care...

Research from University Hospital broadens understanding of burn care research.(Clinical report)
June 29, 2009... According to recent research from Netherlands, "Although arginine has been shown to improve healing in rodents and in small induced wounds in healthy volunteers, little is known about the effects of arginine supplementation on healing of...

Research in the area of burn care research reported from I. Goutos and colleagues.
June 29, 2009... According to a study from Aylesbury, the United Kingdom, "Hand-foot or palmar-plantar erythrodysesthesia syndrome is an infrequent complication of chemotherapy treatment." "Patients present to a variety of disciplines, including burns...

Researchers from Drexel University, Medical Department provide details of new studies and findings in the area of burn care research.
June 29, 2009... "We conducted this Institutional Review Board-approved retrospective study to compare Aquacel (R) Ag Hydrofiber (R) dressing (Aquacel Ag) to a standard dressing for the treatment of partial thickness burns in children. We used the St,"...

Studies from F.W. Fuller and co-researchers in the area of burn care research published.
June 29, 2009... "Silver sulfadiazine cream has an enviable safety record in burn treatment. However, it side effects, exemplified by allergic reactions to its sulfadiazine moiety, silver staining of the treated burn wound, hyperosmolality, methemoglobinemia,...

Study data from J.M. Mourot and colleagues update understanding of burn care research.
June 29, 2009... According to a study from the United States, "A retrospective analysis of all pediatric patients admitted for acute burn treatment during a 7-year period was conducted to examine patients who underwent femoral artery catheterization and discuss...

Findings from University of Washington in injury infection and critical care reported.(Report)
June 29, 2009... According to recent research published in the Journal of Trauma - Injury Infection and Critical Care, "Iliosacral screws are commonly used for fixation of pelvic ring injuries. Previous reports using different screw insertion techniques have...

New injury infection and critical care research from Hallym University, Medical Department described.
June 29, 2009... "Endoscopic reduction has become common for reducing medial orbital wall fractures because of its various advantages. Nevertheless, there is no standard method of nasal packing to support the orbital contents to maintain the reduction,"...

Reports from Harvard University advance knowledge in injury infection and critical care.
June 29, 2009... "We sought to identify patient and institutional variables predictive of a withdrawal of care order (WOCO) in trauma patients. We hypothesized that the frequency of WOCO would be higher at trauma centers," scientists in the United States report...

Reports on injury infection and critical care findings from Army provide new insights.
June 29, 2009... According to a study from the United States, "The role of primary repair (PR) of modern day war-related colon injuries remains controversial. Retrospective review of medical records of combat-wounded soldiers with colon injuries sustained...

Research from C. Mains and co-researchers yields new findings on injury infection and critical care.(Report)
June 29, 2009... According to a study from the United States, "Optimizing human resources at trauma facilities may increase quality of care. The purpose of this study was to assess whether staffing changes within a Level I trauma center improved mortality and...

Research from Nanjing University in the area of injury infection and critical care published.
June 29, 2009... According to recent research from Nanjing, People's Republic of China, "Secondary brain damage plays a critical role in the outcome of patients with traumatic brain injury (TBI). The mechanisms underlying secondary brain damage are complex."...

Research from R. Ramchand and colleagues has provided new data on injury infection and critical care.
June 29, 2009... According to recent research from the United States, "The misuse of alcohol and illicit drugs is implicated with injury and repeat injury. Admission to a trauma center provides an opportunity to identify patients with substance use problems and...

Research in the area of injury infection and critical care reported from Hebei Medical University.
June 29, 2009... "It is known that tibial diaphyseal fractures are often associated with the posterior malleolar fracture (PMF). There are a few studies on tibial shaft fractures with respect to posterior malleolus fracture," scientists in Shijiazhuang,...

Research results from University of Miami update understanding of injury infection and critical care.
June 29, 2009... "Pedestrian-related crashes cause an estimated 1.2 million deaths and 50 million injuries worldwide. There were 32,590 nonfatal injuries reported among children 0 to 14 years of age in the United States in 2006," scientists in the United States...

Studies from Chang-Gung University update current data on injury infection and critical care.
June 29, 2009... According to recent research from Taiwan, "For functional reconstruction of a thumb metacarpophalangeal joint defect with loss of opposition, we need to address both joint mobility and thumb opposition. Free vascularized second toe joint...

Study data from M.T. Cudnik et al provide new insights into injury infection and critical care.
June 29, 2009... According to recent research published in the Journal of Trauma - Injury Infection and Critical Care, "Trauma centers improve outcomes compared with nontrauma centers, although the relative benefit of different levels of major trauma centers...

Study findings from M. Schuller et al broaden understanding of injury infection and critical care.
June 29, 2009... "Intramedullary nailing is the treatment of choice in tibia fractures allowing for closed fracture reduction and internal fixation. Small-diameter nails that preserve the endosteal blood supply act as load-sharing devices after proximal and...