Anti-Infectives Week articles from June 2004

Anti-Infectives Week archives from June 2004

New compounds antifungal and anticancer but inactive against HIV-1 and bacteria.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- New alpha-(N)-heterocyclichydrazones have antifungal and anticancer properties but are inactive against HIV-1 and bacteria. According to recent research from Italy, "A series of 3- and...

Tenofovir regimens increase K65R selection to confer multiple NRTI resistance.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Tenofovir regimens increase K65R selection to confer multiple nucleoside reverse transcriptase inhibitor resistance. According to recent research published in the journal Antimicrobial Agents and...

Altered immune reaction linked to immunosuppressive potential of oral bactreria.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Altered immune reaction may be linked to the immunosuppressive potential of oral bactreria. According to recent research published in the Journal of Endodontics, "The purpose of this study was to...

Prophylactic levofloxacin spawns drug-resistant microbes in cancer patients.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Prophylactic levofloxacin spawns drug-resistant microbes in cancer patients. "Gram-positive breakthrough infections pose a major drawback to the use of quinolones for antibacterial prophylaxis in...

Children recovering from stem-cell transplants suffer diminished resistance.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Children recovering from stem cell transplants suffer from diminished resistance. "The hematopoietic system of the young child acquires, through time, the ability to cope with exposure to a number...

Cyanovirin-N antiviral activity evaluated.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Scientists evaluated cyanovirin-N antiviral activity using lentiviral vectors pseudotyped with filovirus envelope glycoproteins. According to published research from the United States and Spain,...

Encouraging antibiotic portfolio discussed at European meeting.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Bayer Pharmaceuticals Corporation continues to demonstrate its dedication to research and development in the anti-infective arena as evidenced by encouraging data presented at this year's European...

Serine protease from Bombyx mori larvae exhibits antiviral activity.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- A serine protease from the digestive juice of Bombyx mori larvae exhibits antiviral activity against nucleopolyhedrovirus. According to recent research from Japan, "A protein showing strong...

Clinical trial to investigate treatment for CIDP.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Bayer HealthCare Biological Products Division has announced a new international clinical trail that will investigate its immunoglobulin intravenous product (IGIV), called Gamunex, to treat patients with...

Drug development strategic alliance consummated and funded.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Theravance, Inc., announced that the strategic alliance with GlaxoSmithKline (GSK), previously announced on March 31, was consummated and funded after receiving the requisite regulatory and Theravance...

FDA approves Fluticasone Propionate Cream.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Fougera has received U.S. Food and Drug Administration (FDA) approval for Fluticasone Propionate Cream 0.05%. Fougera had previously received first (tentative) FDA approval in February 2003 for...

Company finds compounds with anticancer, antibacterial activity.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Lorus Therapeutics, Inc., announced the discovery of novel low molecular weight compounds with anticancer and antibacterial activity. The finding comes after 3 years of research by Lorus scientists...

The antibiotic geldanamycin arrests cancer cell growth mechanisms.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- The antibiotic geldanamycin arrests cancer cell growth mechanisms. According to a study from France, "the effects of geldanamycin (GA), an ansamycin antibiotic in development as a lead anticancer...

vanA cluster rearrangements reduce drug resistance in enterococci.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- vanA cluster rearrangements result in a reduction in glycopeptide resistance in vancomycin-resistant enterococci. "The molecular characterization of five clinical isolates of vanA-containing...

Biopharmaceutical company reports net loss in first quarter 2004.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Xoma Ltd. (Xoma) announced results for the quarter ended March 31, 2004. For the first quarter of 2004, the company recorded a net loss of $20.2 million or $0.24 per share compared with $13.1...

New HIV clinical program with Alferon LDO launched in Africa.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Hemispherx Biopharma, Inc., (HEB) has entered into an agreement with the World Foundation Aids Research and Prevention to launch a clinical trial in HIV with its experimental product Alferon LDO, a...

Phlorotannins from brown alga E. cava inhibit HIV-1 RT and protease.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Phlorotannins from the brown alga E. cava inhibit HIV-1 reverse transcriptase and protease. "The bioassay-directed isolation of a marine brown alga, Ecklonia cava, afforded four phlorotannin...

Body composition changes more prominent in HIV-infected patients on HAART.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Body composition changes are more prominent in HIV-infected patients on highly active antiretroviral therapy. According to recent research published in the Scandinavian Journal of Infectious...

HIV-1 non-B subtype likely to develop rapid resistance following HAART.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- HIV-1 non-B subtypes are likely to develop rapid resistance following highly active antiretroviral treatment. "Effective antiretroviral treatment (ART) has significantly reduced the morbidity and...

Simulect safe in pediatric renal transplant with low HHV-6 or EBV infection risk.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Simulect appears safe in pediatric renal transplant patients with a low HHV-6 or EBV infection risk. According to recent research from Canada, "Herpes virus reactivation is of increasing interest...

Allicin holds promise for chronic inflammatory diseases.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Allicin holds promise for chronic inflammatory diseases. According to a study from Israel, "Allicin, a major ingredient of fresh garlic extract that is produced during the crushing of garlic...

Research into parasite movement may help fight malaria.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Researchers at the University of North Carolina at Chapel Hill have discovered a new protein in the cell wall of parasites that helps them move between cells and cause diseases such as malaria. The...

Vaccines for infectious diseases with cutaneous symptoms reviewed.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Scientists review vaccines and immunotherapies for the prevention of infectious diseases having cutaneous manifestations in a recent issue of the Journal of the American Academy of Dermatology. ...

QR-435 displays significant influenza A therapeutic effect in animals.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- The Quigley Corporation (QGLY) reported that intranasal application by spray of Quigley Pharma's QR-435 demonstrated efficacy in significantly reducing the severity of illness in ferrets infected with...

DisperMox 600-mg launched, offers accurate dosing for otitis media.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Ranbaxy USA Inc. (RUSA), a wholly owned subsidiary of Ranbaxy Laboratories Limited (RLL), announced the nationwide availability of new DisperMox (amoxicillin tablets for oral suspension) 600-mg tablets....

Sharps disposal by mail system meets EPA guidelines.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- In keeping with the new U.S. Environmental Protection Agency (EPA) recommendations for the safe home disposal of needles, lancets, and syringes, Becton, Dickinson and Company (BDX) offers its BD Sharps...

Novel synthesis of protease inhibitors yield potent anti-HIV activity.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Novel synthesis of protease inhibitors yield potent anti-HIV activity. "Novel indium-mediated radical cyclization reactions of aliphatic iodoalkynes have been studied. Treatment of iodoalkynes with...

Antimicrobial use increases risk of drug-resistant Salmonella infection.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Prior antimicrobial agent use increases the risk of sporadic infections with multidrug-resistant Salmonella enterica serotype typhimurium. "Several strains of multidrug-resistant (MDR) Salmonella...

Second round of preclinical anti-sepsis animal studies competed.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- CytoGenix, Inc., (CYGX) announced the successful completion of the second round of preclinical animal studies, demonstrating that the company's DNA antibacterial compound is effective in controlling the...

Licensee begins sales of "Ixora for Women".
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- LAM Pharmaceutical Corp. (LAMP), a biomedical company focused on the development and commercialization of novel wound healing and transdermal drug delivery systems, announced that Ixora Bio Medical Co.,...

Patient enrollment completed for three phase III trials of dalbavancin.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Vicuron Pharmaceuticals Inc. (MICU) has completed enrollment in three phase III clinical trials involving more than 1,500 patients designed to support registration of once-weekly dalbavancin for the...

Pentraxin 3 helps control fungal recognition and phagocytosis.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Pentraxin 3 helps control fungal recognition and phagocytosis. "Pentraxin 3 (PTX3) is a tumor necrosis factor and interleukin-1beta-stimulated gene that encodes a long PTX with proinflammatory...

Dalbavancin effective against methicillin-resistant Staphylococcus aureus.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Dalbavancin is effective against methicillin-resistant Staphylococcus aureus. According to a study from Italy, "Infections due to methicillin-resistant Staphylococcus aureus (MRSA) are an important...

Antimicrobial peptide Nisin is spermicidal and bactericidal.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Antimicrobial peptide Nisin is a spermicidal and bactericidal. "Sexually transmitted infections and unplanned pregnancies present a great risk to the reproductive health of women. Therefore,...

A. fumigatus variant has decreased susceptibility to multiple antifungals.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Aspergillus fumigatus variant has decreased susceptibility to multiple antifungals. "Isolates of Aspergillus fumigatus that demonstrate resistance to itraconazole (ITZ) have been described...

FDA approval granted for generic anti-infective medication.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration approved Falcon Pharmaceuticals, Ltd.'s (Falcon) generic Ofloxacin Ophthalmic Solution U.S.P, 0.3%. Falcon is an affiliate of Alcon, Inc., (ACL). Ofloxacin is...

Linezolid effective against VREF in premature infant.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Linezolid was used to resolve hospital-acquired VREF infection in a premature baby. According to a study from the United States, a "4 1/2-month-old, 26-week premature infant with multiple...

Antibiotic-loaded collagen-hyaluronic acid matrix potentially a skin substitute.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Antibiotic-loaded collagen-hyaluronic acid matrix could potentially be a skin substitute. According to recent research from South Korea, "The 1-ethyl-(3-3-dimethylaminopropyl) carbodiimide...

Ravuconazole lysine phosphoester effective against pulmonary aspergillosis.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Ravuconazole lysine phosphoester is effective against pulmonary aspergillosis. According to recent research published in the journal Antimicrobial Agents and Chemotherapy, "Ravuconazole is a new...

Efavirenz induces strong inhibition of SREBP-1c-dependent lipogenic pathway.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Efavirenz induces a strong inhibition of the SREBP-1c-dependent lipogenic pathway. According to recent research from France, "A serious metabolic syndrome combining insulin-resistance,...

Genotypic analyses of lactobacilli show marked variation in tannase activities.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Genotypic analyses of lactobacilli show a marked variation in tannase activities. "A total of 77 tannase producing lactobacilli strains isolated from human feces or fermented foods were examined...

Protein of Treponema denticola inhibits binding step of collagen phagocytosis.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Major outer sheath protein of Treponema denticola inhibits the binding step of collagen phagocytosis. According to recent research published in the journal Cellular Microbiology, "Bacterial...

European launch announced for new rapid test for severe colitis.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Meridian Bioscience, Inc., (VIVO) announced that it has begun to sell its newest product, ImmunoCard Toxins A&B, in the European market. This new test detects toxins produced by strains of the...

Penile prosthesis infection rates decrease with InhibiZone use, study shows.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- A retrospective study published in the April issue of The Journal of Urology reported a statistically significant decrease in original penile prosthesis infection rates, showing the benefits of...

FDA approval granted to make, sell generic anti-infective drug.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Bausch & Lomb (BOL) has received U.S. Food and Drug Administration approval of the company's Abbreviated New Drug Application (ANDA) to manufacture and sell ofloxacin ophthalmic solution, 0.3%,...

MRP8 and MRP14 re-expressed by tissue macrophages in chronic infection.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- MRP8 and MRP14 are re-expressed by tissue macrophages in chronic infection. According to recent research from Germany, "Macrophages are decisive cells for the course of leprosy as they phagocytose...

Patient enrollment commences for PPI-0903 antibiotic phase I trial.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Peninsula Pharmaceuticals, Inc., announced that patient enrollment has begun in a phase I trial of its third product candidate, PPI-0903, after receiving approval for its Clinical Trial Application...

$1.5B annual cost of surgical site infections can be reduced.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- A research paper published in the American Journal of Infection Control said a systematic approach to preparing patients for surgery can reduce both secondary, hospital-acquired patient infections and...

Re-infection with Wuchereria bancrofti is common in Tanzania.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Re-infection with Wuchereria bancrofti is common in Tanzania. According to published research from Denmark, "The results of surveys, for human bancroftian filariasis, carried out in 1975 and 1991...

Once-daily Valcyte prevents CMV after kidney transplant in study.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Research conducted in the Division of Transplantation at the University of Miami School of Medicine, Florida, has found that at least 3 months of therapy with a single daily dose of the antiviral...

Patent granted for germicidal device to prevent nosocomial infections.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Catheter site infections are among the most common and serious nosocomial infections. UVSolutions announced that its patented catheter site disinfection system, also patented for wound care, is a...

Novel porcine model of neonatal sepsis developed.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- A novel porcine model of neonatal sepsis was developed. According to a study from Japan, "Sepsis and its sequela remain a major source of morbidity and mortality in neonates despite advances in...

Treatment may reduce mortality from major systemic infection.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- An experimental therapy that combines an antibiotic with a synthetic anti-inflammatory drug, designed at the University of Virginia (U.Va.) Health System, has shown early promise in dramatically...

Physician finds promise in study of novel injectable antibiotic.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- An antibiotic currently being tested in clinical trials produced a 74% cure rate for hospitalized patients with possibly life-threatening, complicated skin and skin structure infections (cSSSI). ...

Streptococcal inhibitor of complement interactions investigated.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Researchers report the results of an investigation into interactions of streptococcal inhibitor of complement (SIC) and its proteolytic fragments with the human beta defensins in a recent issue of...

Company gets grant for development of P. aeruginosa vaccine.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Juvaris BioTherapeutics, Inc., a private biotechnology company, announced that it has received a phase I small business innovation research grant from the U.S. National Institute of Allergy and...

Polycomplexes of poly(acrylic acid) and streptomycin sulfate characterized.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Antimicrobial polycomplexes of poly(acrylic acid) and streptomycin sulfate have been characterized. In a recent study from Kazakstan, "[c]omplex formation between streptomycin sulfate and...

NMR evidence found for independent domain structures in zoocin A.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- NMR evidence is found for independent domain structures in the antibacterial exoenzyme, zoocin A. According to recent research from the University of Alabama, "NMR was used to obtain spectroscopic...

PLGA microspheres suitable for ocular peptide delivery.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- PLGA microspheres show promise as a system to deliver therapeutic peptides to the eye. Scientists in Italy performed "an in vitro/in vivo investigation on poly(lactide-co-glycolide) (PLGA)...

Predictive population dose-response assessed for Cryptosporidium parvum.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Predictive population dose-response is assessed for Cryptosporidium parvum. According to a study from the University of Miami, "Data validation of safe doses of pathogens in drinking water...

Human Coronavirus 229E in nasal specimens detected by RT-PCR hybridization assay.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- The human Coronavirus 229E in nasal specimens was detected by an RT-PCR hybridization assay. According to recent research from France, "A novel human Coronavirus (HCoV) was" recently recognized...

Antibiotic activity of field-collected Streptomycetes characterized.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Scientists have used genetic and phenotypic traits of Streptomycetes to characterize the antibiotic activities of field-collected microbes. "Although antibiotic production may contribute...

Biopharmaceutical company announces additions to fungicide patent portfolio.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Paradigm Genetics, Inc., (PDGM) announced that the company has been issued two U.S. patents covering the discovery of two novel gene targets in two distinct biochemical pathways by which fungi produce...

FDA approves amoxicillin and clavulanate potassium for oral suspension.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Teva Pharmaceutical Industries Ltd. (TEVA) announced that the U.S. Food and Drug Administration has granted approval for the company's abbreviated New Drug Application for Amoxicillin and Clavulanate...

Structural motif of alpha-helical antimicrobial peptides identified.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Scientists have identified a common structural motif of alpha-helical antimicrobial peptides. According to a study from the United States, "Sequences of 221 alpha-helical antimicrobial peptides...

Histopathologic changes in kidney and liver correlate with SPE B production.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Histopathologic changes in kidney and liver correlate with streptococcal pyrogenic exotoxin B production. According to recent research from Taiwan, "Previous studies show that isogenic mutants...

Collaboration to develop various dosage forms of cephalosporin antibiotics.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Par Pharmaceutical, Inc., has entered into an agreement with Orchid Chemicals & Pharmaceuticals Ltd. to develop and market generic drugs. The companies will initially collaborate on the development...

Avelox promotes rapid remission of chronic bronchitis symptoms in study.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Chronic obstructive pulmonary disease (COPD) patients with acute exacerbations of chronic bronchitis (AECB) who took the antibiotic Avelox (moxifloxacin HCl) for 5 days experienced significantly faster...

Licorice extract significantly improves learning and memory.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Licorice extract significantly improves learning and memory in mice. According to a study from India, "In the traditional system of medicine, the roots and rhizomes of Glycyrrhiza glabra (family:...

FDA requests and approves new name for infection imaging product.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Palatin Technologies, Inc., (PTN) has reached an agreement with the U.S. Food and Drug Administration (FDA) on the name NeutroSpec for Palatin's infection imaging product that is in the final stages of...

New campaign against reimportation launched.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration (FDA) joined the North Carolina Association of Pharmacists (NCAP) and the North Carolina Board of Pharmacy (NCBOP) in Raleigh recently to announce the launch of a...

Anidulafungin NDA does not support labeling claim for esophageal candidiasis.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Vicuron Pharmaceuticals Inc. (MICU) has received an approvable letter from the U.S. Food and Drug Administration (FDA), but the letter indicated that the company's New Drug Application submission for...

FDA clears new fungal infection diagnostic test.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Associates of Cape Cod, Inc., (ACC) announced that the U.S. Food and Drug Administration has cleared Glucatell, a serological assay that is intended for the qualitative detection of beta-glucan in the...

FDA approves gastrointestinal selective antibiotic.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Salix Pharmaceuticals, Ltd., (Nasdaq:SLXP) announced that the U.S. Food and Drug Administration (FDA) granted marketing approval for Xifaxan(rifaximin) tablets in 200 mg for the treatment of...

(+)-Inophyllum B and (+)-calanolide A candidates for anti-HIV therapy.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- (+)-Inophyllum B and (+)-calanolide A may be candidates for anti-HIV therapy. "(-)-Quinine-catalyzed intramolecular oxo-Michael addition (IMA) of 7-hydroxy-5-methoxy-8-tigloylcoumarins was...

New protease inhibitors offer improved clinical effectiveness.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- New protease inhibitors offer improved clinical effectiveness. "The introduction of the protease inhibitor (PI) class to the armamentarium of drugs used to treat HIV-1 infection has led to...

Rare cutaneous protothecosis successfully treated with fluconazole.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- A rare case of cutaneous protothecosis was successfully treated with fluconazole. "Protothecosis is an infection caused by achlorophyllic algae of the genus Prototheca which rarely affects humans....

Treatment of long-term catheter-related Brevibacterium described.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Effective treatment of long-term catheter-related brevibacterial infection has been described. According to published research from Belgium, "Brevibacterium has been reported as a rare cause of...

FDA grants 510(k) clearance for Legionella pneumophila test.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- BD Diagnostics, a segment of Becton, Dickinson and Company (BDX), announced that the U.S. Food and Drug Administration (FDA) has granted 510(k) clearance for the BD ProbeTec ET Legionella pneumophila...

Diagnostics/research company names chief financial officer.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Signet Laboratories, Inc., named John Hallinan as chief financial officer. Hallinan has more than 20 years experience providing financial and operational management to technology firms. Most...

Medical advisory board assembled to guide development of CDAD treatment.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Optimer Pharmaceuticals, Inc., has recently assembled a group of medical experts to guide the development of its lead drug candidate, OPT-80, for the treatment of Clostridium difficile-associated...

Method to measure kinetics of penicillin thermal decomposition reported.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Researchers have developed a method for the rapid estimation of kinetic parameters for thermal decomposition of penicillins by modulated thermogravimetric analysis. "Modulated thermogravimetic...

FDA approves Avelox (moxifloxacin HCI) for community-acquired pneumonia.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration (FDA) has approved a supplemental new drug application for Avelox (moxifloxacin HCI) Tablets and I.V. for the treatment of community acquired pneumonia (CAP)...

Phase II study results of pulmonary delivery of amikacin presented.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Aerogen, Inc., (AEGN) presented results from a phase IIa clinical study that compared pulmonary delivery of aerosolized amikacin among Aerogen's proprietary Pulmonary Drug Delivery System (PDDS) and...