Anti-Infectives Week articles from February 2009

Anti-Infectives Week archives from February 2009

Research in the area of B-cell lymphoma reported from I.S. Kim and colleagues.
February 2, 2009... "ATP-binding cassette transporter G2 (ABCG2) is the most recently described transporter of the multidrug-resistance pump and it promotes resistance to anticancer drugs such as doxorubicin, mitoxantrone, topotecan, and SN-38. Of the ABCG2...

Data on drug resistance discussed by P.M. Easton and colleagues.
February 2, 2009... "The aim of the study was to establish knowledge and understanding of methicillin-resistant Staphylococcus aureus (MRSA) among patients, visitors and members of the general public accessing health services and to identify public education needs...

New data from T.D. Chugh et al illuminate research in drug resistance.
February 2, 2009... According to a study from New Delhi, India, "There has been a remarkable progress in the prevention, control and even eradication of infectious diseases with improved hygiene and development of antimicrobials and vaccines. However, infectious...

New drug resistance findings from Wayne State University published.(Report)
February 2, 2009... "Glycopeptides have historically been the drugs of choice for the treatment of infections caused by methicillin-resistant Staphylococcus aureus (MRSA). However, the continued selective pressure has led to the emergence of non-susceptible...

New drug resistance research from C. Berglund and co-researchers described.
February 2, 2009... "Recent studies have shown a predominance of type IV SCCmec among the methicillin-resistant Staphylococcus aureus (MRSA) isolated in the low endemic areas of Orebro County and the western region of Sweden. However, many of these isolates were...

New injury infection and critical care research from University of Liverpool outlined.
February 2, 2009... According to recent research published in the Journal of Trauma - Injury Infection and Critical Care, "In recent years, performance monitoring has gained increasing attention as a tool for evaluating the delivery of health care services and is...

New injury infection and critical care study findings have been reported by scientists at University of Kentucky.
February 2, 2009... "Delayed transfer to a trauma center due to unnecessary imaging results in suboptimal patient outcome and increases healthcare costs. Unnecessary imaging may result from beliefs regarding trauma center requirements and legal concerns,"...

New injury infection and critical care study findings have been reported from D. Giannikas et al.
February 2, 2009... "Open transtrapezium injuries of the thumb are not common and sufficiently described injuries. We have clinically and radiologically evaluated six patients with transtrapezium injury of the thumb," researchers in Rion, Greece report (see also...

New injury infection and critical care study findings recently were published by V.W. Mccray and co-researchers.(Report)
February 2, 2009... According to recent research from the United States, "Nonoperative management of splenic injury is common with reported success rates between 83% and 97%. However, there are no specific protocols for nonoperative observation published in the...

Research from University of Toronto in injury infection and critical care provides new insights.
February 2, 2009... "Background., Violence and traumatic brain injury (TBI) are two major public health concerns. This violence-related TBI, however, has not been studied in Canada and there is little literature on a profile of risk factors and injury severity...

Research from X.L. Griffin and co-authors reveals new findings on injury infection and critical care.(Report)
February 2, 2009... "The aim of this study was to review the evidence regarding the use of low intensity pulsed ultrasound (LIPUS) in the management of acute long bone fractures. Systematic review of Medline, Embase, and CINAHL databases," scientists in Coventry,...

Research on injury infection and critical care described by W. Michlits and colleagues.(Report)
February 2, 2009... According to recent research from Salzburg, Austria, "Soft tissue defects overlying the Achilles tendon often occur after traumatic ruptures of the Achilles tendon or because of pressure ulcers in patients suffering from circulatory problems....

Researchers from Chang-Gung University provide details of new studies and findings in the area of injury infection and critical care.(Report)
February 2, 2009... According to a study from Taiwan, "Because the complications of vertebroplasty are serious and can include new fracture, we retrospectively evaluated potential risk factors for new fracture after vertebroplasty. Our hypothesis is that...

Scientists at University of Florida publish research in injury infection and critical care.
February 2, 2009... According to recent research from the United States, "The international Classification Injury Severity Score (ICISS) uses anatomic injury diagnoses to predict probability of survival (Ps) computed as the product of the survival risk ratios...

Scientists at University of Washington detail research in injury infection and critical care.
February 2, 2009... "Pneumomediastinum occurs in up to 10% of patients with blunt thoracic and cervical trauma. Mandatory evaluation of all patients with bronchoscopy and esophageal imaging to exclude a major injury has been recommended," scientists in the United...

Studies from G. Stadter and co-authors have provided new information about injury infection and critical care.(Report)
February 2, 2009... According to recent research published in the Journal of Trauma - Injury Infection and Critical Care, "Side impact crashes, the most lethal type, account for 26% of all motor vehicle crashes in the United States. The purpose of this study is to...

Studies from P.S.L. Dasilva and colleagues reveal new findings on injury infection and critical care.
February 2, 2009... "Repeat head computed tomography (CT) is standard practice for traumatic brain injury (TBI) at many centers. The few studies available in children remain unclear over the value of repeat CT within 24 hours to 48 hours of lesion in such...

Studies from Stanford University yield new information about injury infection and critical care.
February 2, 2009... "Background., Triage of the trauma patient in the field is a complex and challenging issue, especially deciding when to use aeromedical transport. The American College of Surgeons Committee on Trauma recently defined ail acceptable under-triage...

Studies in the area of injury infection and critical care reported from Y. Uysal and co-researchers.
February 2, 2009... In this recent report, researchers in Ankara, Turkey conducted a study "To assess prognostic value of the Ocular Trauma Score (OTS) in childhood open-globe injuries. This retrospective, interventional case series included 61 children with...

Study findings on injury infection and critical care are outlined in reports from New York University.(Report)
February 2, 2009... "This study was performed to evaluate when patients recover sufficiently to drive an automobile after operative repair of various other lower extremity fractures. A computerized driving simulator was developed and tested," scientists in the...

Study results from J. Colombo and colleagues in the area of injury infection and critical care published.
February 2, 2009... Researchers in the United States conducted a study "To describe early effects of sympathetic (SNS) and parasympathetic nervous system (PSNS) activities measured by heart rate (HR) and respiratory rate variabilities simultaneously with...

Yale University, Medical Department details research in injury infection and critical care.(Report)
February 2, 2009... According to recent research from the United States, "The purpose of this study was to determine whether trauma team oversight of patient management would positively affect efficiency of care as defined by improved patient throughput, with...

Studies from Meharry Medical College, Medical College further understanding of breast cancer.
February 9, 2009... According to recent research published in the journal Breast Cancer Research and Treatment, "2-Methoxyestradiol (2ME), a natural derivative of estradiol, is currently evaluated in clinical trials for breast cancer. The current study aims to...

Report summarizes cancer study findings from University of Colorado.
February 9, 2009... According to recent research from the United States, "To evaluate the safety, pharmacokinetics and determine the recommended dose of the selective apoptotic antineoplastic drug, OSI-461 administered on a twice-daily regimen to patients with...

CLSI Publishes 2009 Antimicrobial Susceptibility Testing Standards.
February 9, 2009... CLSI recently published updated editions of its antimicrobial susceptibility testing (AST) standards, Performance Standards for Antimicrobial Disk Susceptibility Tests; Approved StandarduTenth Edition (M02-A10), and Methods for Dilution...

New clostridium findings from Queen's University published.
February 9, 2009... According to recent research published in the American Journal of Infection Control, "The Resources for infection Control in Hospitals (RICH) project assessed infection control programs and rates of antibiotic-resistant: organisms (AROs) in...

Nanoemulsion Kills Highly Resistant Bacteria Found in Patients With Cystic Fibrosis.(Clinical report)
February 9, 2009... Scientists at NanoBio Corp. and the University of Michigan have demonstrated in the laboratory that their novel topical nanoemulsion kills the highly resistant strains of bacteria that cause chronic illness and death among individuals with...

Data on infection control reported by R.L. Stricof and co-researchers.
February 9, 2009... "In July 2005, New York State legislation requiring the mandatory reporting of specific hospital-associated infections (HAIs) was passed by the legislature and signed by the governor. In an effort to measure the impact of this legislation on...

New infection control data have been reported by N.J. Bennett and co-authors.
February 9, 2009... "Forty-five infection control nurses responded to a Survey that assessed a smaller hospital ( "Only a few program elements that need further development were identified. Approximately half (52.3%) of the respondents agreed that the...

Research by M.B. Knapp and colleagues in infection control provides new insights.
February 9, 2009... According to recent research from the United States, "To guide development of infection control education, we conducted a pilot needs assessment to determine Current infection control knowledge, identify potential gaps between knowledge and...

Studies from J. Forman et al add new findings in the area of infection control.
February 9, 2009... According to a study from the United States, "infection control professionals and hospital epidemiologists are accustomed to using quantitative research. Although quantitative studies are extremely important in the field of infection control...

Studies from University of Louisville describe new findings in infection control.(Report)
February 9, 2009... "Infection prevention and control education for hospital-based health care personnel has differed across organizations because of a lack of identified practice competencies," scientists in the United States report (see also Infection Control)....

Data on drug resistance described by researchers at University of Guelph.
February 16, 2009... "Resistance to a broad spectrum of structurally diverse chemotherapeutic drugs (multidrug resistance; MDR) is a major impediment to the treatment of cancer. One cause of MDR is the expression at the tumor cell surface of P-glycoprotein (Pgp),...

New research on drug resistance from K. Ikeda and co-authors summarized.(Report)
February 16, 2009... "An efflux function induced by multidrug resistance-associated proteins (MRPs) contributes to the mechanisms of resistance to methotrexate (MTX). Since it has been reported that the human Caucasian colon adenocarcinoma cell line (Caco-2) shows...

Reports from A.R. Larsen and colleagues advance knowledge in drug resistance.(Report)
February 16, 2009... According to recent research from Copenhagen, Denmark, "The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) infections has changed worldwide. From being strictly nosocomial, MRSA is now frequently found as a...

Research from Harbor-UCLA Medical Center in the area of drug resistance described.(Report)
February 16, 2009... According to recent research from the United States, "We have previously shown the importance of mgrA and sarA in controlling autolysis of Staphylococcus aureus, with MgrA and SarA both being negative regulators of murein hydrolases. In this...

Research on drug resistance discussed by scientists at University of Halle-Wittenberg.
February 16, 2009... "Novel multidrug resistance (mdr) modulators have been proved as inhibitors of P-glycoprotein (P-gp). We first investigated the in vitro effects of selected compounds in human cancer cells on multidrug resistance reversal effects compared to...

New findings reported from University of Texas describe advances in infection research.
February 16, 2009... According to recent research from the United States, "Temozolomide is a relatively new chemotherapeutic agent frequently associated with selective CD4(+) T-tymphocytopenia." "Patients with cell-mediated immune defects are at higher risk...

Data on breast cancer published by J.S. Lagas and colleagues.
February 23, 2009... According to recent research from Netherlands, "Diclofenac is an important analgesic and anti-inflammatory drug, widely used for treatment of postoperative pain, rheumatoid arthritis, and chronic pain associated with cancer. Consequently,...

Research conducted at Georgetown University has provided new information about cancer.
February 23, 2009... "Prostate cancer (PCa) frequently develops antiapoptotic mechanisms and acquires resistance to anticancer drugs. Therefore, identifying PCa drug resistance determinants should facilitate designing more effective chemotherapeutic regimens,"...

Findings from University of Illinois in drug resistance reported.
February 23, 2009... "Multidrug resistance protein 7 (MRP7; ABCC10) is an ATP-binding cassette transporter which is able to transport amphipathic anions and confer resistance to docetaxel and, to a lesser extent, vincristine and paclitaxel. Whereas some detail on...

Hiroshima University details research in drug resistance.
February 23, 2009... "To investigate the prevalence of integrons and antimicrobial resistance genes in Salmonella recovered from animals in Japan. Forty-eight out of ninety-four (51.1%) Salmonella isolates showed multidrug resistance phenotypes and harboured at...

Investigators at Shandong University zero in on drug resistance.
February 23, 2009... "One of the common hindrances to successful chemotherapy is the development of multidrug resistance (MDR) by tumor cells to multiple chemotherapeutic agents. In this regard, P-glycoprotein (P-gp) acts as an energized drug pump that reduces the...

Data on burn care research detailed by researchers at University of Iowa, Medical Department.
February 23, 2009... According to recent research published in the Journal of Burn Care & Research, "Inhalation injury consists of a multitude of insults, the first of which is the toxic gases inhaled during the combustion of organic and inorganic substances." ...

Findings in burn care research reported from University of Washington, Medical Department.(Report)
February 23, 2009... According to recent research published in the Journal of Burn Care & Research, "Reasons for distress after burn injuries have not been codified based oil any type of acceptable empirical or statistical technique. The unique design methodology...

Recent findings from M.D. Peck and co-authors highlight research in burn care research.
February 23, 2009... According to a study from the United States, "One of the most hotly debated aspect of inhalation injury is the ''best'' method of mechanical ventilation." "Mechanical ventilation protocols differ between both physicians and burn centers,...

Reports from University of Wisconsin highlight recent research in burn care research.(Report)
February 23, 2009... According to a study from the United States, "Effective dressings for donor sites or other partial thickness wounds must promote removal of nonviable or necrotic tissue, eradication and prevention of microbial infiltrate, exudate absorbance,...

Reports outline burn care research from Loyola University.(Report)
February 23, 2009... "The purpose of this study was to screen burn patients for alcohol use disorders to identify those at increased risk for repeat injury and adverse effects of alcohol use. We examined associations of at-risk drinking and dependence symptoms as...

Reports outline burn care research from University of Iowa.
February 23, 2009... "The American Burn Association, Children's Burn Foundation, and Christian Medical College in Vellore, India have partnered together to improve pediatric burn care in Southern India. We report the demographics and outcomes of burns in this...

Reports summarize burn care research study results from University of Texas.
February 23, 2009... According to a study from the United States, "A second potential therapeutic option for the parenchymal damage caused by inhalation injury is systemic administration of intravenous agents." "The unique nature of the effects of the burn and...

Research on burn care research discussed by scientists at University of Iowa.
February 23, 2009... According to recent research from the United States, "Foreign medical service trips, though worthy, raise questions about efficacy, durability, and cultural sensitivity. A structured intervention by a multidisciplinary team can lead to...

Researchers at University of Utah publish new data on burn care research.
February 23, 2009... "In 1989, Williamson published a survey of nutrition care practices in burn centers. Nutrition practices have evolved since then; we conducted a study to determine the current scope of nutrition care in burn centers," investigators in the...

Researchers from University of Rochester detail new studies and findings in the area of burn care research.
February 23, 2009... "Contact burns from clothing irons are a common injury seen in children. These injuries occur when an unattended iron is within reach of toddlers in its upright position," researchers in the United States report (see also Burn Care Research)....

Scientists at University of Utah, Medical Department detail research in burn care research.
February 23, 2009... According to recent research published in the Journal of Burn Care & Research, "A nursing-driven protocol for sedation and analgesia for our burn unit was developed based on Society of Critical Care Medicine recommendation. Our goal was to...

Study data from E.A. Henneken and colleagues update understanding of informetrics.(Report)
February 23, 2009... "In this paper we present a number of metrics for usage of the SAO/NASA Astrophysics Data System(ADS). Since the ADS is used by the entire astronomical community, these are indicative of how the astronomical literature is used," investigators...

Study results from T.L. Palmieri and colleagues broaden understanding of burn care research.(Report)
February 23, 2009... "Inhalation injury remains a significant source of morbidity, and mortality in children with burn injury. The purpose of this study is to analyze the incidence, demographic characteristics, and outcomes for children who have sustained burn...