Anti-Infectives Week articles from August 2008

Anti-Infectives Week archives from August 2008

New findings reported from Ohio State University describe advances in cancer.
August 4, 2008... " The over-expression of glutathion S-transferase Pi (GST pi) in tumors and inhibitory effect of GST pi to JNK are two possible causes of the development of drug-resistance in chemotherapy. This research is to develop a novel pH-controlled NO...

New drug delivery study findings have been reported by researchers at University of Granada.
August 4, 2008... According to recent research from Granada, Spain, "Because of the fundamental importance of new therapeutic routes for cancer treatment, a number of. systems based on colloidal particles as vehicles for the delivery of chemotherapeutic agents...

Findings from Replidyne, Inc. broaden understanding of drug resistance.(Report)
August 4, 2008... According to recent research from the United States, "The aim of this study was to describe the rates of antimicrobial susceptibility of Staphylococcus aureus from skin and wound infections reported from nine regions of the USA during 2005-07...

New drug resistance research from I. Shalit et al outlined.
August 4, 2008... According to recent research published in the Journal of Antimicrobial Chemotherapy, "Increased antibiotic consumption is associated with increased bacterial resistance worldwide. We aimed to analyse antibiotic consumption and potential...

New drug resistance research from S. Chusri et al outlined.
August 4, 2008... According to a study from Hat Yai, Thailand, "Acetone, ethyl acetate, 95% ethanol and aqueous extracts of Quercus infectoria (Q. infectoria) demonstrated significant antibacterial activities against all strains of methicillin-resistant...

New findings from C.D. Kemp and co-authors in the area of injury infection and critical care published.(Report)
August 4, 2008... According to recent research from the United States, "The purpose of this study was to define donation patterns and lost donor opportunities in severe traumatic brain injury (TBI) patients. The trauma registry was queried for all deaths after...

New injury infection and critical care study findings have been reported by researchers at Uppsala University.(Report)
August 4, 2008... According to a study from Uppsala, Sweden, "Injury-specific instruments with good psychometric properties are valuable in the assessment of health status after trauma. Previous studies of burn-specific health have attempted to create broad...

Recent findings in injury infection and critical care described by researchers from University of Washington.
August 4, 2008... "Trauma center physicians need to know the patient's prognosis to make appropriate clinical decisions when they take over the care of a transferred patient. We sought to compare the survival of injured patients after transfer to a trauma center...

Reports from A.C. Mosenthal and colleagues advance knowledge in injury infection and critical care.
August 4, 2008... "Ten percent to 20% of trauma patients admitted to the intensive care unit (ICU) will die from their injuries. Providing appropriate end-of-life care in this setting is difficult and often late in the patients' course," investigators in the...

Reports outline injury infection and critical care research from University Hospital.(Report)
August 4, 2008... "In up to 31% of cases, nonsurgical treatment of midshaft clavicular fractures leads to unsatisfactory results such as nonunion, brachial plexus irritation, shortening and limited function of the shoulder. To date, various implants have been...

Research conducted at Johns Hopkins University has provided new information about injury infection and critical care.
August 4, 2008... "Although soft armor vests serve to prevent penetrating wounds and dissipate impact energy, the potential of nonpenetrating injury to the thorax, termed behind armor blunt trauma, does exist. Currently, the ballistic resistance of personal body...

Research from H.A. Werman and co-researchers in the area of injury infection and critical care published.
August 4, 2008... According to recent research from the United States, "Various decision algorithms have been developed for use in the prehospital setting to analyze those trauma patients who do not require spinal immobilization. The feasibility of applying...

Research in the area of injury infection and critical care reported from University of Michigan.
August 4, 2008... "Nonoperative management for blunt splenic injury (BSI) has become gold standard, but the role of angiographic embolization (AE) is still controversial for bleeding. We postulated that splenic AE for BSI would have superior outcomes compared...

Research results from T. Kanchan and colleagues update understanding of injury infection and critical care.
August 4, 2008... In this recently published study, investigators in Mangalore, India conducted a study "To describe the epidemiology and trends of traumatic deaths among children and adolescents in Manipal, Southern India. Analysis of all trauma deaths in...

Researchers at University of Alabama have published new data on injury infection and critical care.
August 4, 2008... "Golf carts have become a popular mode of transportation off of the links because of their small size, low maintenance, and ease of use. Case reports suggest severe, debilitating injuries as a consequence of golf cart incidents," investigators...

Researchers at University of Arkansas target injury infection and critical care.
August 4, 2008... "Evidence suggests that 90% of children with traumatic spleen injuries can be successfully managed nonoperatively. In Washington State, significant interhospital variation in pediatric spleen management led to the development and implementation...

Researchers at University of Texas publish new data on injury infection and critical care.(Clinical report)
August 4, 2008... In this recent report, researchers in the United States conducted a study "To examine police compliance with policies for the proper use of conductive electrical devices (CEDs) and, in turn, track any associated medical events following CED...

Researchers from Tri-Service General Hospital report on findings in injury infection and critical care.(Report)
August 4, 2008... "Unstable distal clavicle fractures may benefit from surgical treatment. This report described a new method with transacromial extra-articular Knowles pin fixation to treat these unstable fractures," scientists in Taipei, Taiwan report (see...

Studies from T. Wisborg and co-researchers in the area of injury infection and critical care published.(Report)
August 4, 2008... According to recent research from Hammerfest, Norway, "Norway has 50 trauma hospitals serving a geographically disperse population (4.6 million) and many have low trauma case loads. We showed that personnel find functioning as a team especially...

Data on microbial research published by A. Hachani and colleagues.
August 4, 2008... According to a study from Marseille, France, "Type III secretion systems (T3SS) are present in many pathogenic gram-negative bacteria and mediate the translocation of bacterial effector proteins into host cells. Here, we report the phenotypic...

New drug resistance study results from B.V.S. Krishna et al described.
August 11, 2008... "An evaluation of Chromogenic MRSA medium (CMRSA), MRSASelect (MRSAS) and Oxacillin Resistance Screening Agar (ORSA) was performed to determine the optimum medium providing a rapid and sensitive method for methicillin-resistant Staphylococcus...

Research conducted at Columbus Children's Hospital has provided new information about drug resistance.
August 11, 2008... According to recent research published in the British Journal of Cancer, "Alterations in the tumour suppressor p53 have been reported in tumour-associated stromal cells; however, the consequence of these alterations has not been elucidated. We...

Research from University of California provides new data on drug resistance.(Report)
August 11, 2008... According to recent research published in the Journal of Pharmacology and Experimental Therapeutics, "ABCC4 encodes multidrug resistance protein 4 (MRP4), a member of the ATP-binding cassette family of membrane transporters involved in the...

Research results from S. Tanaka and colleagues update understanding of enzyme research.
August 11, 2008... "A new adjuvant therapy, individual adjuvant therapy (IAT), which is individualized according to the results of real-time reverse-transcription polymerase chain-reaction (RT-PCR) for O-6-methylguanine-DNA methyltransferase (MGMT), was used to...

New heart transplants study findings have been reported from Ruhr University.
August 11, 2008... "Survival for heart transplantation (HTx) patients is limited by nephrotoxicity of the calcineurin inhibitors cyclosporine and tacrolimus. To determine whether genetic factors are involved in the development of renal dysfunction under...

New findings from University of Maryland, Medical Department in the area of anti-infectives published.
August 18, 2008... In this recent report published in the journal Infection Control and Hospital Epidemiology, researchers in the United States conducted a study "To assess the rate of and the risk factors for the detection of methicillin-resistant S. aureus...

Research reports from C.C. Hsu and co-authors provide new insights into artificial neural networks.
August 18, 2008... According to a study from Kaohsiung, Taiwan, "Use of active surveillance cultures for methicillin-resistant Staphylococcus aureus (MRSA) for all patients admitted to the intensive care unit has been shown to reduce nosocomial transmission....

New DNA research study findings have been published by scientists at Ernst-Moritz-Arndt University.
August 18, 2008... According to a study from Greifswald, Germany, "The Tet repressor (TetR) mediates the most important mechanism of bacterial resistance against tetracycline (Tc) antibiotics. In the absence of Tc, TetR is tightly bound to its operator DNA; upon...

Findings from University of California advance knowledge in drug resistance.(Clinical report)
August 18, 2008... Researchers in the United States conducted a study "To evaluate the adequacy of discharge room cleaning and the impact of a cleaning intervention on the presence of methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant...

New drug resistance data have been reported by scientists at Stony Brook University.(Clinical report)
August 18, 2008... "In critically ill intubated patients, signs of respiratory infection often persist despite treatment with potent systemic antibiotics. The purpose of this study was to determine whether aerosolized antibiotics, which achieve high drug...

Reports by M. Walberg and co-researchers describe recent advances in hospital epidemiology.
August 18, 2008... In this recently published study, investigators in Rud, Norway conducted a study "To implement a system for monitoring of rare events based on statistical process control charts. Statistical process control plotting by g chart of clinical...

Studies from Nagasaki University have provided new information about anti-infectives.
August 25, 2008... According to a study from Sakamoto, Japan, "We compared the potency of SMP-601, a novel carbapenem, with that of vancomycin in a murine model of hematogenous bronchopneumonia infection caused by methicillin-resistant Staphylococcus aureus...

Data on drug resistance described by M. Marcos et al.
August 25, 2008... According to recent research published in the Journal of Antimicrobial Chemotherapy, "The impact of appropriate antimicrobial therapy and antimicrobial resistance on the outcome of bacteraemia due to Enterobacter spp. remains unclear. The aim...

New findings reported from M. Higashide and co-authors describe advances in drug resistance.
August 25, 2008... "Staphylococcus saprophyticus is a uropathogenic bacterium that causes acute uncomplicated urinary tract infections, particularly in female outpatients. We investigated the dissemination and antimicrobial susceptibilities of 101 S....

New findings reported from University of Antwerp describe advances in drug resistance.
August 25, 2008... "The intraspecific relationships among a collection of Enterococcus faecium isolates comprising probiotic cultures and human clinical isolates were investigated through the combined use of two high-resolution DNA-fingerprinting techniques. In...

Recent studies by L. Soulsby and co-authors add new data to drug resistance findings.
August 25, 2008... According to recent research published in the Journal of Antimicrobial Chemotherapy, "The evolution of resistance to microbes is one of the most significant problems in modern medicine, posing serious threats to human and animal health. The...

Findings in burn care research reported from University of Berlin.
August 25, 2008... According to recent research from Berlin, Germany, "Aims of the study were to examine positive change in people with severe burn injuries and to examine the impact of related constructs, demographic and medical variables on Post Traumatic...

New burn care research data have been reported by M. Nisanci and co-authors.
August 25, 2008... According to a study from Etlik, Turkey, "Treatment of postburn deformities of the hand is a real challenge to reconstructive surgeons. A functional reconstruction was achieved with two sensate island flaps on two discrete pedicles in a case...

New burn care research study findings have been reported by R. Mulholland and colleagues.
August 25, 2008... "Thirty-seven referrals to a liaison psychiatry service after deliberate self-harm by burning were compared with a control group of people referred to the same service after deliberate self-harm by other means," scientists writing in the...

Research from B. Masters and co-researchers in the area of burn care research published.
August 25, 2008... "Nutrition support is an integral part of the multidisciplinary management of a burn. However, the large body of research has lead to some confusion regarding optimal feeding practices," researchers in Doha, Qatar report (see also Burn Care...

Research results from University of Washington update understanding of burn care research.(Report)
August 25, 2008... "Modern burn care is a resource intensive endeavor requiring specialized equipment, personnel, and facilities in order to provide optimum care. The costs associated with burn injury to both patients and society as a whole can be multifaceted...

Scientists at University of Washington describe research in burn care research.
August 25, 2008... "Management and proper approach to pediatric palm burns remains unclear. Our burn center's approach includes early, aggressive range of motion therapy, combined with a period of watchful waiting, reserving grafting only for those palms that do...

Studies conducted at P. Gentile et al on burn care research recently published.
August 25, 2008... According to recent research from Rome, Italy, "Extra-oral implants represent a valid alternative technique in aesthetic reconstruction of the craniofacial district in oncology surgery. Two female patients were selected; they were treated from...

Studies from M. Gandhi and co-researchers yield new data on burn care research.
August 25, 2008... "Toxic epidermal necrolysis (TEN) is a rare life-threatening disease mostly related to drug ingestion. Apoptotic keratinocytes lead to separation of the epidermis from dermis and widespread blistering of the skin," researchers in the United...

Study data from Shriners Hospital for Children update knowledge of burn care research.
August 25, 2008... "The respiratory quotient (RQ) is frequently used to predict over or under feeding in burn patients. The purpose of our study was to evaluate the usefulness of RQ obtained from indirect calorimetry to assess feeding adequacy in pediatric burn...

Study findings from University of Sydney provide new insights into burn care research.
August 25, 2008... "Objective of the study is to investigate for the presence of fibrocytes, a leucocyte found at sites of injury with fibroblast-like properties, within pediatric burn wounds. Seventy 3 mm punch biopsies were taken from 53 burn wounds in 33...