Anti-Infectives Week articles from August 2004

Anti-Infectives Week archives from August 2004

Meropenem lung penetration measured by microdialysis.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Microdialysis enables accurate and detailed measurements of antibiotic lung penetration. "Until recently, information on antibiotic pharmacokinetic properties in infected human lung tissue was...

Herbs and spices have antimicrobial and chemopreventive properties.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Herbs and spices have antimicrobial and chemopreventive properties. "Herbs and spices have been used for generations by humans as food and to treat ailments. Scientific evidence is accumulating that...

Reprocessing endoscopes in the United States reviewed.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Researchers review the reprocessing of endoscopes in the United States in a recent issue of the Journal of Hospital Infection. According to research from the United States, "Endoscopes are used...

FDA approves Levaquin for multi-drug resistant form of S. pneumoniae in CAP.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration (FDA) has approved the fluoroquinolone antibiotic Levaquin (levofloxacin) Tablets/Injection and Levaquin (levofloxacin in 5% dextrose) Injection to treat multi-drug...

Pharmacists highlight antibiotic misunderstanding and overuse in public survey.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- The Royal Pharmaceutical Society of Great Britain (RPSGB) highlighted the need for better understanding of how antibiotics work as part of the campaign to prevent antibiotic resistance. But a...

Role of mhc polymorphism in anti-microbial resistance reviewed.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Researchers review the role of mhc polymorphism in anti-microbial resistance in a recent issue of Microbes and Infection. According to published research from the United States, "The major...

Kleenex to sell tissue that kills viruses.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- First it was everything from dish soap to toothbrushes that promised protection against bacteria. Now the maker of Kleenex plans a tissue that kills viruses. Kimberly-Clark Corp. said its newest...

Decapinol approved in EU; Aloclair Gel approved in U.S.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Sinclair Pharma, plc, has received regulatory approvals for two of its key products, Decapinol and Aloclair Gel, and also provided a year-end trading update in advance of its preliminary results for the...

Method to quantify drug resistance gene expression in Candida developed.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Scientists have developed a method for the rapid quantification of drug resistance gene expression in Candida albicans by reverse transcriptase LightCycler PCR and fluorescent probe hybridization. ...

Expanded EPA approval for Minncare Cold Sterilant in fogging applications.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Cantel Medical Corp. (CMN) subsidiary Minntech Corp. has received expanded approval from the United States Environmental Protection Agency (EPA) for the use of its Minncare Cold Sterilant in fogging...

Efficacy of lipid amphotericin B formulations compared.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Different lipid amphotericin B preparations have similar overall efficacy against Coccidioides immitis infection in mice. In a recent study from Mexico, the "therapeutic efficacy of three lipid...

New classification of diabetic foot infections proposed.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Members of the Infectious Diseases Society of America have proposed a new classification of diabetic foot infections. "The treatment of diabetic foot ulcers is first determined by the presence or...

First predictive diagnostic to combat high sepsis mortality rates released.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- The release of ABP-26, a predictive diagnostic for detecting early signs of sepsis, has been announced by Signet Laboratories, Inc. The diagnostic helps prevent onset and curb mortality rates. ...

Cocos nucifera extract has potent leishmanicidal activity.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- A novel coconut tree extract has demonstrated potent leishmanicidal activity. "The available therapy for leishmaniasis, which affects 2 million people per annum, still causes serious side effects,"...

1,4-Naphthoquinone derivatives have antiviral/antifungal/anticancer activities.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- 1,4-Naphthoquinone derivatives have antiviral/antifungal/anticancer activities. According to recent research from India, "The synthesis and evaluation of some 2-substituted-1,4-naphthoquinones 2,...

Toyama Chemical re-acquires rights to quinolone synthetic antibacterial agent.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Toyama Chemical Co., Ltd., in September 1988, signed a licensing agreement with Bristol Myers-Squibb Company (BMS) to grant the development and sell rights to T-3811 (generic name garenoxacin)...

Macrolide use in food animals poses little risk to humans.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Macrolide use in food animals poses little risk to humans. "The potential impact on human health from antibiotic-resistant bacteria selected by use of antibiotics in food animals has resulted in...

Comments issued on FDA's consumer information release about Glucatell.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Associates of Cape Cod, Inc., (ACC), a manufacturer of endotoxin and beta-glucan detection products, addressed a newly published U.S. Food & Drug Administration (FDA) Consumer Information release...

Sxi1 alpha is not required for virulence of Cryptococcus neoformans.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- The alpha-specific cell identity factor Sxi1 alpha is not required for virulence of Cryptococcus neoformans. According to a study from the United States, "Cryptococcus neoformans is a human fungal...

West African community joins HIV/AIDS community treatment support program.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- A West African community has joined the network of community-based treatment support programs that form Bristol-Myers Squibb's (NYSE: BMY) real world field test of how HIV/AIDS treatment can best be...

HIV/AIDS drug users shunned by healthcare providers.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- The vast majority of HIV patients in many countries of Asia and Eastern Europe are injecting drug users, and they often lack access to prevention and treatment services because of discrimination and...

Libya opens aid corridor to Sudan while WHO warns of major health catastrophe.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Libya agreed to open a corridor for food aid and other U.N. humanitarian supplies to help about 1.2 million people displaced by the Darfur conflict in western Sudan. An agreement was signed July...

Augmentin antitrust litigation settled.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- GlaxoSmithKline (GSK) has agreed to settle U.S. antitrust cases involving the antibiotic product Augmentin. GSK will pay $92 million (50 million pounds sterling) in settlement of class action...

Pharmaceuticals company announces departure of board members Livolsi and Parenti.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Vicuron Pharmaceuticals Inc. (MICU), announced the resignation of Ubaldo Livolsi, PhD, and retirement of Francesco Parenti, PhD, from the company's board of directors. George F. Horner III,...

SIGA announces the appointment of Bernard L. Kasten, MD as CEO.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- SIGA Technologies, Inc., (NASDAQ: SIGA) announced the appointment of Bernard L. Kasten, MD, as its chief executive officer. Kasten joins SIGA following eight years at Quest Diagnostics where he was...

SARS exposure led to infection among 4.7% of ED workers in Taiwan study.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- SARS exposure led to infection among 4.7% of emergency department workers in a Taiwan study. According to published research from Taiwan, "Of 193 emergency department workers exposed to severe acute...

Antibiotic-resistant syphilis spreading.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- A fast-spreading mutant strain of syphilis has proved resistant to the antibiotic pills that are offered to some patients as an alternative to painful penicillin shots. Since the late 1990s,...

Early diagnosis and treatment paramount in P. boydii infections.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Early diagnosis and treatment are paramount in P. boydii infections. According to a study from the United States, "We present an immunocompromised patient with a painless testicular mass. Usually,...

Testing completed for VScan tuberculosis test kit in China.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Medical Services International Inc. (MSITF) has received the latest results from the testing of its VScan tuberculosis (TB) rapid test kit in the People's Republic of China, with results showing that...

Human adenovirus genomes display resistance to chemical disinfectants.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Human adenovirus genomes display resistance to chemical disinfectants. According to recent research published in the Journal of Hospital Infection, "human adenoviruses are model viruses for testing...

Novel mechanism used by infectious agents subverts first line of host defense.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- A novel mechanism used by infectious agents subverts the first line of host defense. According to published research from France, "Some pathogens have evolved to produce proteins, called B-cell...

Terbinafine and amphotericin B effective against Fusarium infection.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- A regimen of terbinafine and amphotericin B can resolve life-threatening Fusarium infections. Physicians in Germany presented a "case of disseminated infection with Fusarium oxysporum following...

Stenotrophomonas maltophilia plays significant role as nosocomial pathogen.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Stenotrophomonas maltophilia plays a significant role as a nosocomial pathogen, challenging both clinicians and microbiologists. According to a study from Turkey, "Stenotrophomonas maltophilia is a...

First Glucatell clinical study results reported.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Associates of Cape Cod, Inc., (ACC) announced that the results of a clinical diagnostic study of Glucatell, its serum test for (1,3)-beta-glucan, have been published in Clinical Infectious Diseases on...

Studies Viread and Emtriva published in JAMA.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Gilead Sciences, Inc., (Nasdaq:GILD) announced the publication of results from two separate studies evaluating the efficacy and safety of Viread (tenofovir disoproxil fumarate) and Emtriva...

Successful BMT possible for anemia in patients with B19 infection.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Use of high-titer IVIg may lead to successful bone marrow transplantation for severe aplastic anemia in a patient with persistent human parvovirus B19 infection. "Persistent infection with human...

MRSA and vancomycin-resistant enterococci associated with adverse outcomes.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci are associated with adverse outcomes. "Two types of cohort studies examining patients infected with...

I50L is signature mutation for ATV resistance in treatment-naive HIV-1-infection.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- I50L is the signature mutation for atazanavir resistance in treatment-naive HIV-1-infected patients. According to a study from the U.S., "Atazanavir (ATV) is a once-daily human immunodeficiency...

Stability and activity of ADAM NNRTIs improved.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- The stability and activity of ADAM non-nucleoside reverse transcriptase inhibitors has been improved. "The alkenyldiarylmethane (ADAM) HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs)...

Six Oregon hospitals recognized for quality in cardiac and infection care.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Six hospitals received Oregon Hospital Quality Awards at the annual conference in Bend, Oregon. The awards, sponsored by OMPRO, OAHHS, and the Office of Rural Health, recognize performance...

Therapeutics company announces preliminary year-end results.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- NeuTec Pharma plc. announces its preliminary results for the year ended 30 June 2004. NeuTec is developing a portfolio of antibody-based therapeutic products directed towards life threatening...

Biopharmaceutical company begins phase III trial of Doripenem.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Peninsula Pharmaceuticals, Inc., announced that following a productive End of Phase 2 meeting with the U.S. Food and Drug Administration (FDA) patient enrollment has begun in the final pivotal phase III...

Organ-specific selection can occur during cryptococcosis.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Organ-specific selection can occur during cryptococcosis. According to recent research published in the journal Infection and Immunity, "Cryptococcus neoformans capsule structure modifications...

T. vaginalis infection in men detected by sampling multiple genitourinary sites.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Trichomonas vaginalis infection in men can be detected by sampling multiple genitourinary sites. According to a study from the U.S., "Variations in estimates of prevalence of trichomoniasis in men...

Biotech company to develop topical antifungal for rhinosinusitis.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- BioDelivery Sciences International (BDSI) announced that the Wall Street Journal has reported on the company's licensing agreement with Accentia Inc. for a topical version of amphotericin B. ...

Japanese drug company reacquires rights to synthetic antibacterial agent.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- On September 30, 1998, Toyama Chemical Co., Ltd. agreed to a licensing agreement with Bristol Myers-Squibb Company (BMS) to grant the development and sell rights to T-3811 (generic name: garenoxacin),...

Nalidixic acid-resistant typhoid fever responds poorly to ofloxacin.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Nalidixic acid-resistant typhoid fever responds poorly to ofloxacin. According to recent research published in the journal Transactions of the Royal Society of Tropical Medicine and Hygiene,...

Therapeutics company reports second quarter increase in product sales.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- MedImmune, Inc., (MEDI) announced that product sales for the 2004 second quarter increased 13% over the 2003 second quarter to $91 million, primarily due to a 10-percent increase in sales of Synagis...

U.S. FDA to review application to market antifungal infection drug.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Schering-Plough Corporation (SGP) reported that the U.S. Food and Drug Administration (FDA) has accepted for review its new drug application (NDA) for posaconazole oral suspension. The review provides...

U.S. NIH awards $13.6 million contract for web-based biomedical data services.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- SRA International, Inc. (SRX), a provider of information technology services to federal government organizations, has been awarded a competitive contract by the National Institute of Allergy and...

NIAID grant awarded to continue development of H. pylori vaccine.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Antex Biologics, a wholly owned subsidiary of Emergent BioSolutions and sister company to BioPort Corporation, has received a $2 million grant from the National Institute of Allergy and Infectious...

Africa: Vaginal gel promising for HIV prevention.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- With hope of an effective HIV/AIDS vaccine a decade away, the International Partnership for Microbicides (IPM) says a new class of drugs that can protect women from infection during sex looks promising....

Data offers best HIV RNA response in given highly active antiretroviral therapy.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Data from a new study with the HIV protease inhibitor Invirase (saquinavir mesylate) have demonstrated the best HIV RNA response yet seen in a large group of HIV-infected patients given highly active...

Microbicide research at USAID gets funding boost in House bill.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- The Alliance for Microbicide Development, the Global Campaign for Microbicides, and the International Partnership for Microbicides announced in July 2004 that the House Appropriations Subcommittee on...

Mothers, babies in South Africa will continue nevirapine monotherapy for now.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- South Africa's Ministry of Health will continue providing the anti-AIDS drug Nevirapine as a monotherapy to mothers and babies until new treatment regimens become available, reported the UN Integrated...

Number of antiretroviral development strategies on the increase.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Pharmaprojects reports a rise in the number of antiHIV drug development strategies being adopted by pharmaceutical companies. There are currently 186 antiretroviral compounds under active...

Solid organ transplantation in HIV-infected patients feasible in era of HAART.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Solid organ transplantation in HIV-infected patients is becoming feasible in the era of highly active antiretroviral therapy. According to a study from the U.S., "HIV is generally regarded as an...

Lay health advisor-based AIDS programs successfully employ safe sex practices.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Lay health advisor-based AIDS programs successfully employ safe sex practices. According to recent research from the Netherlands, "Two studies describe the effectiveness of acquired immunodeficiency...

T cell activation/maturation help predict treatment response in HIV infection.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- T cell activation and maturation help predict treatment response in HIV infection. "To determine whether markers of T cell activation and maturation are independently predictive of the response to...

Activated macrophage/microglial cells have neuroprotective role in HIV infection.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Activated macrophage and microglial cells have a neuroprotective role in HIV infection. According to a study from France, "Microglial cells and macrophages are the only cells within the central...

Activated naive B cells in HIV-1 infection down-regulate CXCR5 on their surface.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Activated naive B cells in HIV-1 infection down-regulate CXCR5 on their surface. According to recent research published in the Journal of Medical Virology, "The CD27- (naive) B cells of HIV-1...

Anti-HIV activity found in peptides derived from SDF-1 C-terminal sequence.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Anti-HIV activity has been found in peptides derived from the SDF-1 C-terminal sequence. According to investigators in Italy, "The entry of the human immunodeficiency virus type 1 (HIV-1) into...

Bidirectional SF2/ASF-/SRp40-dependent ESE regulates HIV-1 rev/env/vpu/nef mRNAs.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Bidirectional SF2/ASF-/SRp40-dependent exonic splicing enhancer regulates HIV-1 rev/env/vpu/nef gene expression. According to recent research from Germany, "The integrated human immunodeficiency...

C-terminus alterations of HIV-1 vpr do not correlate to disease intensity.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- C-terminus alterations of the HIV-1 vpr gene do not correlate to disease intensity. According to recent research from the U.S., "The C terminus of the human immunodeficiency virus type 1 (HIV-1)...

Configurations of metallocyclams and relevance to anti-HIV activity elucidated.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Configurations of metallocyclams, and their relevance to anti-HIV activity, have been elucidated According to a study from Scotland, "Antiviral cyclam macrocycles block viral entry into cells by...

HIV-1 genomes reside within actively transcribed host genes in resting CD4 cells.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- HIV-1 genomes reside within actively transcribed host genes in resting CD4+ cells. "Resting CD4+ T-cell populations from human immunodeficiency virus type 1 (HIV-1)-infected individuals include...

Minor baseline HIV protease mutation predict 90M mutation at virological failure.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- A minor baseline HIV protease mutation predicts a 90M mutation at virological failure. "The association between minor mutations in human immunodeficiency virus (HIV) protease at baseline and...

Nef enhances infectivity of HIV-1 particles produced in primary T cells.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Nef enhances the infectivity of HIV-1 particles produced in primary T cells. According to a study from the U.S., "The Nef protein enhances human immunodeficiency virus type 1 (HIV-1) replication...

SIN HIV-1-based vectors identify synthetic endothelial cell-specific promoters.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Self-inactivating HIV-1-based vectors identify synthetic endothelial cell-specific promoters. "Transcriptional targeting is a desirable property for many gene transfer applications. Because...

New HIV/AIDS tests more accurate, reproducible, cheaper, study shows.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Results from a multi-site study evaluating two new assays from Guava Technologies, Inc. that dramatically lower the cost and difficulty of AIDS diagnosis and treatment monitoring were presented at the...

Study results of protease inhibitor for AIDS presented at conference.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- The protease inhibitor (PI) LEXIVA (fosamprenavir calcium, formerly GW433908, or 908) in combination with abacavir and lamivudine demonstrated sustained efficacy and safety after long-term treatment (96...

University medical researchers discuss findings at International AIDS Conference.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Researchers from the Stanford University School of Medicine discussed their most recent findings during the 15th International AIDS Conference in Bangkok, Thailand. Topics discussed included...

Companies to develop co-package of Combivir and Viramune for developing world.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- GlaxoSmithKline, plc, (GSK) and Boehringer Ingelheim have signed a letter of intent for an accelerated development program for a co-package for Combivir (lamivudine/zidovudine) and Viramune (nevirapine)...

Antimicrobial resistance found among Helicobacter pylori isolates.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Investigators report antimicrobial resistance among Helicobacter pylori isolates in the United States. "Helicobacter pylori is the primary cause of peptic ulcer disease and an etiologic agent in...

Preclinical data presented on anticancer agents, immunomodulatory molecules.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Bioniche Life Sciences, Inc., (BNC), a fully-integrated human and animal biopharmaceutical company, was among the presenters at the 12th International Congress of Immunology and 4th Annual Conference of...

Novel cis-acting element facilitates minus-strand DNA synthesis during HBV RT.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- A novel cis-acting element facilitates minus-strand DNA synthesis during hepatitis B virus reverse transcriptase. According to a study from South Korea, "Hepadnaviruses replicate through reverse...

Herpesvirus protease inhibited by dimer disruption.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Herpesvirus protease is inhibited by dimer disruption. "Kaposi's sarcoma-associated herpesvirus (KSHV), like all herpesviruses, encodes a protease (KSHV Pr), which is necessary for the viral lytic...

KSHV-encoded latency-associated NA inhibits lytic replication by targeting Rta.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen inhibits lytic replication by targeting Rta. According to recent research from the U.S., "Like other...

Kaposi sarcoma-associated herpesvirus GP K8.1 is dispensable for virus entry.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Kaposi sarcoma-associated herpesvirus glycoprotein K8.1 is dispensable for virus entry. According to recent research from the U.S., "Kaposi's sarcoma-associated herpesvirus (KSHV) is considered the...

Inducible defense mechanism against nitric oxide in Candida albicans reported.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- An inducible defense mechanism against nitric oxide in Candida albicans has been studied. According to a study from the United States, "The yeast Candida albicans is an opportunistic pathogen that...

T-cell differentiation distinct in persistent human virus infection.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- T-cell differentiation is distinct in persistent human virus infection. According to a study from England, "Confusion surrounds the current classification of memory and effector T-cell subsets and...

Center on hygiene and health in the home, community opens in Massachusetts.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- A national center on hygiene and health in the home and community, aimed at helping the public better understand how to minimize the growing risk of infections acquired in the community, has been...

PB1-F2 creates variably sized pores in planar lipid membranes.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- PB1-F2 creates variably sized pores in planar lipid membranes. According to a study from the U.S., "A frameshifted region of the influenza A virus PB1 gene encodes a novel protein, termed PB1-F2, a...

Utility of antibiotic-loaded cement spacers reviewed.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- The utility of antibiotic-loaded bone cement spacers in knee replacement have been reviewed. "There are two types of temporary spacers: block or non-articulating spacers and articulating or mobile...