Anti-Infectives Week articles from April 2004

Anti-Infectives Week archives from April 2004

Antimalarial agents derived from Benin medicinal plants.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Agents with strong activity against drug-resistant malaria parasites have been isolated from traditional African medical plants. In a study from Benin, "[t]wenty extracts from nine Benin medicinal...

Chromium(III) complex inhibits Shigella dysenteriae.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- A Schiff base complex of chromium(III) is an efficient inhibitor for the pathogenic and invasive potential of Shigella dysenteriae. "A Schiff base complex of chromium(III),...

Antibiotics alter the normal bacterial flora in humans.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Bacteria that are resistant to antibiotics can live in the human intestines for at least 1 year. Professor Charlotta Edlund from the Karolinska Institute in Stockholm, Sweden, and Research Professor...

Antioxidant gene therapy protects hearing against antibiotic-mediated injury.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Antioxidant gene therapy protects hearing against antibiotic-mediated injury. According to a study from the United States, "aminoglycosides are commonly used antibiotics that often induce...

Pressure treatment reduces infectivity of prions.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Pressure treatment at 60 degrees C reduces the proteinase K resistance and infectivity of prions. "High hydrostatic pressure is a mild technology compared with high temperatures and is commonly...

Camels may be vector for multiresistant Salmonella.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Camels could be a vector for multiresistant strains of Salmonella. In a recent study, a "total of 714 samples consisting of feces, mesenteric lymph nodes, liver, spleen, abdominal and diaphragmatic...

Bacteria manipulate Rho to enhance their survival.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Bacteria manipulate Rho to enhance their survival. According to a study from the United States, "Many features of cell behavior are regulated by Rho family GTPases, but the most profound effects of...

Skeletal imaging agent approved by FDA.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Draximage, Inc., the radiopharmaceutical subsidiary of Draxis Health, Inc., (DRAX) (DAX), has received approval from the U.S. Food and Drug Administration (FDA) to produce and market a new formulation...

Ritonavir treatment may benefit glioblastoma patients.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Ritonavir therapy may be beneficial for glioma patients. "Glioblastoma is a therapeutic challenge as a highly infiltrative, proliferative, and resistant tumor," scientists in France explained....

Factive receives marketing approval in Canada, ready for U.S. launch.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Genome Therapeutics Corp. (GENE) has received marketing approval for Factive (gemifloxacin mesylate) tablets for the treatment of acute bacterial exacerbations of chronic bronchitis from the Therapeutic...

Postoperative infection with MRSA is related to socioeconomic background.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Researchers find patients from deprived areas had a much greater postoperative infection rate than patients from better socioeconomic backgrounds. According to a study from England, "Infectious...

Trial results advance development of vaccine for travelers' diarrhea.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- A clinical trial undertaken by the U.K. biotechnology company Microscience at the St. George's Vaccine Institute at St. George's Hospital Medical School in London, England has demonstrated the safety...

Artemisinin-derived trioxane dimers have potent antimalarial/anticancer activity.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- A series of artemisinin-derived trioxane dimers have potent antimalarial and/or antitumor activity. According to recent research from the United States, in "only four chemical steps from naturally...

Betulonic acid-based agents active against HIV, influenza A, other viruses.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- A group of betulonic acid-based agents have demonstrated activity against a variety of viruses, including HIV. In a study from Russia, "[b]etulonic acid amides with aliphatic and heterocyclic...

Cell-penetrating, Rev-binding peptides can protect against HIV.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- A novel class of cell-penetrating, Rev-binding peptides may protect against HIV infection. "New therapeutic agents able to block HIV-1 replication are eagerly sought after to increase the...

Complete genome sequence of Saccharopolyspora erythraea reported.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Aventis Bulk S.p.A. has successfully sequenced the whole genome of Saccharopolyspora erythraea. The strain is an industrial overproducer of erythromycin antibiotic. The work was carried out in...

Cote d'Ivoire medicinal plants yield antiparasitic agents.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Several promising antiparasitic agents have been derived from Cote d'Ivoire medicinal plants. In a study from Switzerland, the "antitrypanosomal activity of 101 crude ethanol extracts derived from...

Fungal derivatives show promise as HIV integrase inhibitors.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- A series of fungal derivatives are highly active against a key HIV enzyme. "HIV-1 integrase is a critical enzyme for replication of HIV, and its inhibition is one of the most promising new drug...

Novel benzophenones show promise as anti-HIV NNRTIs.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Novel benzophenone non-nucleoside reverse transcriptase inhibitors (NNRTIs) are highly active against drug-resistant strains of HIV. In a recent study from Japan, the agents "GW4511, GW4751, and...

FDA approves once-daily Floxin Otic (ofloxacin otic solution).
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Daiichi Pharmaceutical Corporation announced the recent approval by the U.S. Food and Drug Administration (FDA) of a once-daily for 7 days dosing regimen of Floxin Otic (ofloxacin otic solution) 0.3%, a...

Chemotherapy and HAART feasible for HIV-NHL patients.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Simultaneous chemotherapy and HAART regimens are feasible for HIV patients with non-Hodgkin lymphoma. Researchers in Italy "evaluated replication of human immunodeficiency virus (HIV) and the...

Hepatotoxic effects comparable for all ARVs.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- The drugs used to fight HIV infection all have comparable hepatotoxic effects. HIV patients "frequently present with elevated levels of serum transaminases (alanine aminotransferase [ALT] and/or...

Impact of HCV coinfection on risk of HAART-induced liver damage reviewed.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- The impact of HCV infection on the risk of HAART-induced liver damage has been reviewed. "Drug-induced liver injury (DILI) is the elevation of liver enzyme and/or bilirubin levels caused by the use...

Mitochondrial-to-nuclear DNA ratio may mark mitochondrial toxicity.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- The ratio of mitochondrial DNA to nuclear DNA may mark mitochondrial toxicity in nucleoside-treated HIV patients. "Nucleoside analogues inhibit human DNA polymerase gamma. As a result, they can...

Routine resistance testing can improve ART outcome in experienced patients.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Routine resistance testing can improve the outcome of ART in heavily-treated HIV patients. According to recent research from the United States, the "long-term efficacy of making resistance testing...

Untimed drug levels powerful tool for measuring treatment compliance.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Untimed drug levels are a powerful tool for measuring compliance with anti-HIV treatment. In a recent study, scientists in the United States "examined cross-sectionally the relationship between...

Antiretroviral therapy does not prevent HPV-induced genital lesions.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Antiretroviral therapy does not protect HIV+ women against the effects of HPV infection. In a study from Italy, the "effect of antiretroviral therapy on the natural history of human papillomavirus...

Vitamin A supplements may increase risk of vertical HIV transmission.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Vitamin A supplements may increase the risk of vertical HIV transmission. According to recent research from the United States, "[m]icronutrient status has been associated with shedding of human...

IFN-alpha with ribavirin can suppress virus-specific immunity.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Treatment with interferon (IFN)-alpha and ribavirin may impair immune responses to non-HCV viruses. Anti-HCV treatment "combining IFN-alpha and ribavirin (IFN+R) has still poorly defined effects on...

Self-reported hepatitis B vaccination status unreliable among drug users.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Self-reported hepatitis B virus infection and vaccination status among young drug users is unreliable. "Self-reported hepatitis B virus (HBV) infection status and immunization status were compared...

A critical juncture for hemodialysis-related HCV passage is saline flushing.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- A critical juncture for hemodialysis-related HCV passage is saline flushing. According to recent research published in the International Journal of Artificial Organs, "the hepatitis C virus is a...

Functional regions of plasmodial MAEBL protein identified.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Functional regions of the plasmodial MAEBL protein have been identified and characterized. "MAEBL is an erythrocyte binding protein located in the rhoptries and on the surface of mature merozoites,...

Ocular lesions plague many children born with congenital toxoplasmosis.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Ocular lesions plague many children born with congenital toxoplasmosis. According to recent research from France, "the aim of this study was to identify the high-risk factors associated with the...

Orally active fusion inhibitor of respiratory syncytial virus developed.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Scientists have developed an orally active fusion inhibitor of respiratory syncytial virus. According to recent research from the United States, "BMS-433771 was found to be a potent inhibitor of...

Health communication during SARS outbreak described.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- The health communication during the SARS outbreak is described in a recent issue of Emerging Infectious Diseases. According to research from the United States, " Experience with the outbreak of...

Lack of SARS transmission observed among public hospital workers in Vietnam.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- SARS transmission did not occur among health care workers at a public hospital in Vietnam. According to a study from the United States, "Vietnam was one of the first countries affected by the global...

SARS preparedness checklist developed for state and local health officials.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Researchers have developed a SARS preparedness checklist for state and local health officials. "In March 2003, the number of cases of severe acute respiratory syndrome (SARS) was increasing daily...

Results of anti-sepsis preclinical animal trials released.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- CytoGenix, Inc., (CYGX) announced the successful completion of the first phase of preclinical animal studies. These proof-of-concept studies show that the company's lead DNA anti-bacterial compound...

Chronic sinusitis is an immune disorder; antifungal is effective treatment.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Researchers at the University at Buffalo (UB) and the Mayo Clinic have shown that chronic sinusitis is an immune disorder caused by fungus, opening up a promising new avenue for treating this ubiquitous...

Risk of vaccinia transfer after smallpox vaccination low.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- The risk of vaccinia transfer to the hands of vaccinated persons after smallpox immunization is very low if the vaccination site is properly bandaged. According to published research from the United...

Company initiates enrollment in phase II trial for Aurexis.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Inhibitex, Inc., announced that it has commenced enrollment in a phase II clinical trial for Aurexis, a humanized monoclonal antibody being developed as a first-line therapy, in combination with...

Methylene blue virus photoinactivation reviewed.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- The use of MB photoinactivation to remove viral blood product contamination has been reviewed. Scientists in Alabama examined "the current status of the use of methylene blue (MB) photoinactivation...

Ciprofloxacin and sparfloxacin active against multiresistant TB strains.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Ciprofloxacin and sparfloxacin are active against multiresistant strains of Mycobacterium tuberculosis. Researchers in Turkey conducted a study "to determine the activities of rifampicin,...

Rifamycin resistance risk similar for rifampin and rifabutin DOT regimens.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Rifampin- and rifabutin-based regimens carry comparable risks of inducing TB drug resistance. In a recent study, scientists in Tennessee "sought to determine the risk of acquired...

Study demonstrates HealthRenu effectiveness in infection prevention.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- HealthRenu Medical, Inc., (HRUM.OB) announced the completed results of a 2-year clinical study of its products. Daniel Sparks, an orthopedic surgeon, has used the company's products during the last...

Development of indinavir resistance can be insidious.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The develoment of indinavir resistance by HIV can be an insidious process. In a recent study, scientists in the United States "evaluated zidovudine-experienced patients for whom treatment with...

Hairpin probe and gold gets bad bugs glowing.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Using tiny amounts of gold and a genetic "hairpin probe," U.S. scientists have developed a sensor that will aid hospitals in the fight against serious infections such as Staphylococcus aureus,...

Class of enzymes offers new way to kill superbugs.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Scientists from the New Jersey University of Medicine and Dentistry have discovered a whole new class of enzymes that may represent a major advance in understanding the way bacterial cells self...

Oral mucosa defends against Candida albicans infection in humans.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Oral mucosa defends against Candida albicans infection in humans. "Clinical and experimental observations suggest that oral epithelial cells play a key role in host defenses against candidal...

Giving antibiotics within 4 hours of arrival at a hospital improves outcomes.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Giving older patients antibiotics within four hours of their arrival at a hospital for treatment of pneumonia reduces the length of hospital stay, and may reduce the chances of dying, according to a...

ETI-204 prevents death from anthrax exposure in animals.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Scientists from Elusys Therapeutics, Inc., presented data showing that the company's anthrax antibody, ETI-204, provides complete protection from death due to anthrax exposure in two animal species and...

Anti-PRSP efficacy of meropenem evaluated.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The anti-PRSP efficacy of meropenem in South Korea has been evaluated. "With the widespread emergence of antimicrobial resistance, combination regimens of ceftriaxone and vancomycin (C+V) or...

Caspofungin effective for pediatric cancer patients, bone marrow recipients.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Caspofungin is effective against fungal infections in pediatric cancer patients or bone marrow recipients. In a recent study from Italy, caspofungin, "in association with other antifungal drugs,...

Extended interval gentamicin dosing safe for preterm infants.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Extended interval gentamicin dosing is safe and effective for preterm infants. In a recent study from the United States, "[c]onventional interval dosing (CID) and extended interval dosing (EID) of...

Gemifloxacin inhibits cytokine release by LPS-stimulated monocytes.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Gemifloxacin inhibits cytokine release by lipopolysaccharide (LPS)-stimulated human monocytes. In a recent study from California, the "fluroquinolone gemifloxacin was examined for its capacity to...

Methods detects trace levels of swine antibiotics in groundwater.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Scientists from the department of soil, water and climate at University of Minnesota have developed a simple method to quantify two types of antibiotics in animal manures, and surface and ground...

Well-defined antisense technology delineates the abilities of new antimicrobials.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Well-defined antisense technology delineates the abilities of new antimicrobials. "Validation of antibiotic mode of action in whole bacterial cells is a key step for antibiotic drug discovery. In...

Resistance rates of Salmonella enterica serotype Typhi in S. Korea determined.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The prevalence of drug-resistant S. enterica serotype Typhi in South Korea has been determined. Researchers in South Korea conducted a study "to characterize the epidemiological features of...

Three-year contract signed for FDA-approved waterless surgical hand prep.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Effectively preparing hands for surgery will soon become faster and more convenient for many facilities, thanks to a sole-source agreement between HealthTrust Purchasing Group and 3M Medical Division....

Infliximab can induce lupus erythematosus-like eruptions in RA patients.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The monoclonal antibody infliximab can induce lupus-like eruptions in rheumatoid arthritis patients. "Lupus erythematosus-like syndromes have been reported as an adverse effect of anti-tumor...

Chlamydial LPS-specific IgG antibodies useful as sign of lesion infection.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Immunoglobulin G (IgG) antibodies targeting chlamydial LPS are a strong marker of endovascular infection in atherosclerosis patients. "Atherosclerotic lesions often harbor Chlamydophila pneumoniae...

Biopharmaceutical reports increase in cash position and total shareholder equity.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Hemispherx Biopharma, Inc., (HEB) announced results for its year ended December 31, 2003. The company reported a loss of $14,770,000, or $0.42 per share, compared to a loss of $7,424,000 or $0.23...

Immtech continued to prepare for commercialization.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Immtech International, Inc., (IMM) has signed an agreement with Cambrex Charles City, Inc., a subsidiary of Cambrex Corp. (CBM), a provider to the pharmaceutical industry, to develop an enhanced...

Some bacterial toxins could cause cancer.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- A possible link between cancer and toxins or poisons produced by bacteria has been suggested by King's College London scientists at the Society for General Microbiology's meeting in Bath, UK. "As...

Interferon improves survival in HCV patients by negating liver-related death.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Interferon improves survival in HCV patients by negating liver-related death. According to recent research from Japan, "interferon therapy for chronic hepatitis C reduces the risk of hepatocellular...

Exclusive deal signed for new sepsis marker.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Beckman Coulter, Inc., (BEC) announced that it has signed an exclusive licensing agreement with Research and Diagnostic Antibodies, LLC, (R&D Abs) for R&D Abs' inducible nitric oxide (iNOS) monoclonal...

Project aims to develop microbicides to protect women against HIV.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- While condom use remains the most effective protection against sexual transmission of HIV, it is clear that in many parts of the world women are not empowered to insist on it. The urgent need for...

Novel HIV fusion inhibitor T-1249 safe, effective in early trials.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The novel HIV fusion inhibitor T-1249 has proved to be safe and effective in early human trials. According to recent research from North Carolina, "T-1249 is a 39-aa synthetic peptide that...

Pegylated IFN-alpha effective as SARS prophylaxis in macaques.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Pegylated IFN-alpha is an effective prophylactic treatment against SARS in macaques. "The primary cause of severe acute respiratory syndrome (SARS) is a newly discovered coronavirus. Replication of...

Biotechnology company announces adoption of 10b5-1 trading plans.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- United Therapeutics Corporation (UTHR) announced that its Chief Financial Officer Fred Hadeed and its General Counsel Paul Mahon have each adopted pre-arranged stock trading plans to sell a portion of...

Company announces $7.29 million private placement with institutional investors.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- MacroChem Corp. (MCHM) announced that it has raised approximately $7.29 million in gross proceeds from a private placement of its securities to institutional investors. In this private placement,...

Diagnostics company reports 2003 net revenues increase 27.7% from prior year.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- IVAX Diagnostics, Inc., (IVD) reported financial results for the year and fourth quarter ended December 31, 2003. IVAX Diagnostics reported net revenues for the year ended December 31, 2003, of...

Protein-based biopharmaceutical company reports 2003 financial results.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Xoma Ltd. (XOMA) announced its financial results for the year ended December 31, 2003. For the year ended December 31, 2003, the company recorded a net loss of $58.7 million or $0.78 per share...

Applications submitted for fixed-dose coformulation of Viread and Emtriva.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Gilead Sciences, Inc., (GILD) announced the submission of a new drug application to the U.S. Food and Drug Administration (FDA) for marketing approval of a fixed-dose coformulation of the company's...

Health Canada official to join global HIV partnership.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The International Partnership for Microbicides (IPM) announced the appointment of a government official to advance a public-private health partnership. Under the terms of the agreement, Martin...

Anti-HHV-8 therapy effective against multicentric Castleman disease.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Anti-HHV-8 therapy is beneficial for multicentric Castleman disease patients. MCD is "a lymphoproliferative disorder associated with human herpesvirus 8 (HHV-8) infection among persons with human...

Bone marrow features in AIDS patients characterized.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The clinical features of bone marrow in contemporary and historical AIDS cohorts have been characterized. In a recent study, scientists in the United States "compared bone marrow findings in two...

Bone mineral loss frequent in female patients during HAART.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The metabolic disruption associated with antiretroviral therapy often manifests as bone mineral density (BMD) loss in female HIV patients. Reduced BMD and "abnormalities in fat redistribution,...

"Dipping" may throw off conventional measures of sexual behavior.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The practice of "dipping" may throw off conventional measures of male-male sexual behavior. According to scientists in the United States, "[b]rief acts of unprotected anal sex (i.e. 'dipping')...

Effect of within-patient HIV mutation on population-level evolution clarified.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The effects of HIV mutations within patients on population-level viral evolution have been elucidated. "Within-patient HIV evolution reflects the strong selection pressure driving viral escape...

Recombination dynamics of HIV genome determined.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The dynamics of HIV genome recombination have been characterized. "Recombination plays a pivotal role in the evolutionary process of many different virus species, including retroviruses,"...

Interaction between Leishmania and HIV clarified.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The pathological interactions between HIV andLeishmania have been clarified. "Parasitic infections such as leishmaniasis can modulate the life cycle of HIV-1 and disease progression," immunologists...

Effects of HAART on CNS disorders elucidated.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The effect of antiretroviral therapy on CNS disease has been elucidated. According to neurologists in Italy, a "drastic decrease in incidence has been observed for most human immunodeficiency virus...

Thiol/disulfide exchange needed for R4 HIV T-cell fusion during viral entry.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Thiol/disulfide exchange is needed for envelope-mediated T-cell fusion by R4 HIV strains. "Attachment of gp120 to CD4 during HIV-1 entry triggers structural rearrangement in gp120 that enables...