AIDS Vaccine Week articles from October 2008

AIDS Vaccine Week archives from October 2008

New findings reported from St. George's University describe advances in HIV/AIDS.
October 6, 2008... According to a study from London, the United Kingdom, " The rectum is particularly vulnerable to HIV transmission having only a single protective layer of columnar epithelium overlying tissue rich in activated lymphoid cells; thus, unprotected...

New HIV/AIDS study results from University of Amsterdam described.
October 6, 2008... According to a study from Netherlands, "Vaccination of macaques with live attenuated simian immunodeficiency virus (SIV) provides significant protection against the wild-type virus. The use of a live attenuated human immunodeficiency virus...

Scientists at National Institutes of Health release new data on HIV/AIDS.
October 6, 2008... According to recent research published in the Journal of Virology, "Broadly cross-reactive human immunodeficiency virus (HIV)-neutralizing antibodies are infrequently elicited in infected humans. The two best-characterized gp41-specific...

CDC Expands Testing Recommendations for Chronic Hepatitis B Virus Infection.(Report)
October 6, 2008... The U.S. Centers for Disease Control and Prevention (CDC) published new recommendations for health care providers that are designed to increase routine testing in the United States for chronic hepatitis B, a major cause of liver disease and...

Study findings on DNA vaccines are outlined in reports from Wyeth.
October 6, 2008... New investigation results, 'Comparative ability of various plasmid-based cytokines and chemokines to adjuvant the activity of HIV plasmid DNA vaccines,' are detailed in a study published in Vaccine. According to a study from the United States,...

New HIV/AIDS vaccines study results reported from University of Massachusetts, Department of Medicine.
October 6, 2008... Current study results from the report, 'Cross-subtype antibody and cellular immune responses induced by a polyvalent DNA prime-protein boost HIV-1 vaccine in healthy human volunteers,' have been published. "An optimally effective AIDS vaccine...

Study results from Centers for Disease Control and Prevention in the area of HIV/AIDS vaccines published.(Report)
October 6, 2008... New research, 'Viral, HLA and T cell elements in cross-reactive immune responses to HIV-1 subtype A, CRF01_AE and CRF02_AG vaccine sequence in Ivorian blood donors,' is the subject of a report. According to recent research published in the...

Innovative Biopharmaceutical Company, Domainex, has core intellectual property rights granted for Europe.
October 6, 2008... Domainex Ltd (Domainex), an innovative biopharmaceutical company, announced the grant of European Patent No.1442134 for its Combinatorial Domain Hunting (CDH) Technology. Based in London and Cambridge, Domainex is a research company...

New HIV/AIDS findings from S. Mehendale and co-researchers published.
October 13, 2008... "A novel prophylactic AIDS vaccine candidate, consisting of single-stranded DNA for HIV-1 subtype C gag, protease, and part of reverse transcriptase genes, enclosed within a recombinant adeno-associated virus serotype-2 protein capsid (tgAAC09)...

Reports from Duke University, Medical Department describe recent advances in HIV/AIDS.
October 13, 2008... According to a study from the United States, "The death of CD4(+) CCR5(+) T cells is a hallmark of human immunodeficiency virus (HIV) infection. We studied the plasma levels of cell death mediators and products-tumor necrosis factor...

Research conducted at University of Pennsylvania, Medical Department has updated our knowledge about HIV/AIDS.(Report)
October 13, 2008... According to recent research from the United States, "Vectors based on primate-derived adeno-associated virus (AAV) are being considered in the development of genetic vaccines against a number of diseases including infection with HIV-1....

Research on HIV/AIDS published by scientists at St. George's University.
October 13, 2008... According to recent research from London, the United Kingdom, "The mechanisms by which HIV-1 induces chronic pathogenic immune activation associated with disease progression remain unclear despite many years of AIDS research. One proposal...

Researchers at National Institutes of Health publish new data on HIV/AIDS.
October 13, 2008... According to a study from the United States, "Stimulation through TLR represents a new therapeutic approach for enhancing Ab responses to vaccination. Considering that Ab responses are decreased in HIV disease and that B cells express TLR9 and...

Investigators at University of Melbourne release new data on immunization.
October 13, 2008... "T-cell receptors (TCRs) govern the specificity, efficacy, and cross-reactivity of CD8 T cells. Here, we studied CD8 T-cell clonotypes from Mane-A*10(+) pigtail macaques responding to the simian immunodeficiency virus (SIV) Gag KP9 epitope in a...

Research on immunization discussed by scientists at University of Massachusetts.
October 13, 2008... According to a study from the United States, "A major challenge in human immunodeficiency virus type 1 (HIV-1) vaccine development is to elicit potent and broadly neutralizing antibodies that are effective against primary viral isolates....

Research reports from Fred Hutchinson Cancer Research Center provide new insights into HIV/AIDS vaccines.(Report)
October 13, 2008... Research findings, 'On modeling the effects of T-cell vaccines on HIV acquisition and disease,' are discussed in a new report. According to recent research from the United States, "A 'T-cell vaccine' aims at generating cytotoxic T-lymphocytes...

Investigators at University of Washington, Fred Hutchinson Cancer Research Center zero in on vaccines.
October 13, 2008... A report, 'Evaluating a surrogate endpoint at three levels, with application to vaccine development,' is newly published data in Statistics In Medicine. "Identification of an immune response to vaccination that reliably predicts protection from...

Alba Therapeutics Corporation Announces Promotions.
October 13, 2008... Alba Therapeutics Corporation announced the promotions of Linda Arterburn, PhD, Francisco Leon, MD, PhD, Roberto Allen, Esquire, Mark Ginski, PhD, and Kate Huber. "We are pleased to announce the promotions of several of our team members and we...

SAIC Awarded Major Contract to Support the National Cancer Institute.
October 13, 2008... Science Applications International Corporation (NYSE:SAI) announced that its wholly-owned subsidiary SAIC-Frederick, Inc. has been awarded a follow-on contract by the National Cancer Institute (NCI) to provide operations and technical support...

Standard & Poor's Initiates Factual Stock Report Coverage on Mymetics Corporation.
October 13, 2008... Standard & Poor's announced that it has commenced Factual Stock Report coverage on Mymetics Corporation (see also Standard & Poor's). Mymetics Corporation (OTCBB:MYMX), is a biotechnology company focused on developing prophylactic...

VGX Pharmaceuticals Awarded $23.5 Million NIH Contract to Develop DNA-Based Preventive HIV Vaccine Delivered Via Electroporation.
October 13, 2008... VGX Pharmaceuticals (VGX), a developer of DNA vaccines against cancer and infectious diseases that has entered into a definitive merger agreement with Inovio Biomedical (AMEX:INO), announced that the National Institute of Allergy and Infectious...

Findings from Centers for Disease Control and Prevention provide new insights into hepatitic b vaccines.(Survey)
October 20, 2008... According to recent research published in the journal Addiction, "Objectives To estimate the prevalence of hepatitis B virus (HBV), tetanus, hepatitis A virus (HAV) and human immunodeficiency virus (HIV) in injecting drug users (IDUs), risk...

New HIV/AIDS study findings have been reported by A.N. Martins and co-researchers.(Report)
October 20, 2008... "Feline immunodeficiency virus (FIV) is the Lentipirus responsible for an immunodeficiency-like disease in domestic cats (Felis catus). FIV is divided into five phylogenetic subtypes (A, B, C, D, and E), based on genetic diversity," scientists...

Research from Harvard University in the area of HIV/AIDS published.
October 20, 2008... "one of the major challenges that must be met in developing an HIV-1 vaccine is devising a strategy to generate cellular immunity with sufficient breadth to deal with the extraordinary genetic diversity of the virus. Amino acids in the...

Researchers from Merck & Company, Inc. discuss findings in HIV/AIDS.
October 20, 2008... "Results from Merck's phase II adenovirus type 5 (Ad5) gag/pol/nef test-of-concept trial showed that the vaccine lacked efficacy against human immunodeficiency virus (HIV) infection in a high-risk population. Among the many questions to be...

University of California details research in HIV/AIDS.
October 20, 2008... "Mucosal immune responses induced by HIV-1 vaccines are likely critical for prevention. We report a Phase 1 safety and immunogenicity trial in eight participants using the vaccinia-based TBC-3B vaccine given subcutaneously to determine the...

Case Western Reserve University publishes research in HIV/AIDS co-infection epidemiology.(Survey)
October 20, 2008... Research findings, 'Prevalence and predictors of high-risk human papillomavirus infection in a population-based sample of women in rural Uganda,' are discussed in a new report. According to a study from the United States, "High-risk genital...

Findings from University Federal do Rio of Janeiro broaden understanding of HIV/AIDS therapy.
October 20, 2008... Current study results from the report, 'Travel medicine and HIV infection,' have been published. "The number of HIV-infected persons who travel is increasing. This increase arises from those who have benefited from advances in antiretroviral...

Findings in HIV/AIDS vaccines reported from M. Mahto and co-researchers.
October 20, 2008... Researchers detail in 'Measuring the gap: from Home Office to the National Health Service in the provision of a one-stop shop sexual health service in a female prison in the UK,' new data in HIV/AIDS. According to recent research published in...

Recent findings from University of Washington, Department of Medicine highlight research in immunization.(Report)
October 20, 2008... Scientists discuss in 'Independent clinical predictors of impaired response to hepatitis B vaccination in HIV-infected persons' new findings in immunization. "Protective response rates to hepatitis B (HB) vaccination have been reported as low...

New pneumococcal disease vaccines data have been reported by researchers at Children's Hospital of Philadelphia, Department of Pediatrics.
October 20, 2008... Current study results from the report, 'Invasive pneumococcal disease among human immunodeficiency virus-infected children, 1989-2006,' have been published. According to recent research from the United States, "The heptavalent pneumococcal...

Former NewsHour Health Policy Analyst, HIV/AIDS Pioneer Headline ASCP Annual Meeting.
October 20, 2008... Susan Dentzer, one of the nation's most respected health policy journalists, and Robert C. Gallo, a top American HIV/AIDS researcher, will be the keynote speakers at the American Society for Clinical Pathology (ASCP) Annual Meeting in...

Research Attributes Lack of HIV/AIDS Vaccine to Use of Chimpanzees.
October 20, 2008... "A return to the use of chimpanzees in AIDS research and vaccine development is without scientific justification," according to a paper released in the journal Alternatives to Laboratory Animals (ATLA). "An Assessment of the Role of Chimpanzees...

Report summarizes HIV/AIDS study findings from K.M. Watson and co-researchers.
October 27, 2008... "In the absence of a fully effective human immunodeficiency virus (HIV) vaccine, topical microbicides represent an important strategy for preventing the transmission of HIV through sexual intercourse, the predominant mode of HIV transmission...

Research on HIV/AIDS described by G.B. Jacobs and colleagues.(Report)
October 27, 2008... "South Africa has the highest number of HIV-1-infected individuals in the world, with HIV-1 subtype C prevailing. However, HIV-1 subtype C accessory genes are rarely characterized in the country," scientists writing in the journal AIDS Research...

Studies from Vall d'Hebron University update current data on HIV/AIDS.(Report)
October 27, 2008... "Objectives Despite a recent decrease, bacterial pneumonia (BP) is still the most common admission diagnosis in HIV patients. We analyse BP incidence, characteristics and prevention measures," scientists in Barcelona, Spain report (see also...

Study findings from University of Catanzaro Magna Graecia broaden understanding of HIV/AIDS.
October 27, 2008... According to recent research from Italy, "The recently released results of the Merck's Phase IIb ''test-of concept'' vaccine trials have shown no protection from HIV-1 infection in the vaccinated group compared with a control group vaccinated...

New findings from S. Swaminathan and co-researchers in the area of HIV/AIDS co-infection described.(Report)
October 27, 2008... According to recent research from Madras, India, "In many countries, HIV testing among tuberculosis (TB) patients is recommended so that both infections are appropriately treated. Cross-reacting antibodies to HIV antigens have been reported for...

New data from A.D. Hamblin et al illuminate research in immunodeficiency.
October 27, 2008... According to a study from Bournemouth, the United Kingdom, "Patients with chronic lymphocytic leukaemia (CLL) have progressive immunodeficiency and infection is the commonest cause of death. This review seeks to identify the extent of the...

Study data from University of Manitoba, Department of Medical Microbiology update understanding of HIV/AIDS immunology.
October 27, 2008... New investigation results, 'Substantial intrapatient differences in the breadth and specificity of HIV-specific CD8+ T-cell interferon-gamma and proliferation responses,' are detailed in a study published in Journal of Acquired Immune...

Studies from Armed Forces Research Institute of Medical Sciences update current data on HIV/AIDS prevention.(Report)
October 27, 2008... Researchers detail in 'Incidence and characterization of acute HIV-1 infection in a high-risk Thai population,' new data in HIV/AIDS. "The objective of this study was to investigate the incidence, demographics, HIV subtype, and genotypic...

Scientists at Nagasaki University, Institute of Tropical Medicine target HIV/AIDS vaccines.
October 27, 2008... Data detailed in 'Induction of opsonophagocytic killing activity with pneumococcal conjugate vaccine in human immunodeficiency virus-infected Ugandan adults' have been presented. "The levels of IgG determined by ELISA may have limited relevance...

Studies from University of Reading further understanding of HIV/AIDS vaccines.(Report)
October 27, 2008... Research findings, 'Mapping the immune response to the outer domain of a human immunodeficiency virus-1 clade C gp120,' are discussed in a new report. "The outer domain (OD) of human immunodeficiency virus (HIV)-1 gp120 represents an...

Dr. Larry Corey Named New Member of the Institutes of Medicine.
October 27, 2008... Larry Corey, M.D., senior vice president and co-director of the Vaccine and Infectious Disease Institute at Fred Hutchinson Cancer Research Center, today was named as one of 65 new members of the prestigious Institutes of Medicine (IOM) (see...

Governments urged to fight global child killer.
October 27, 2008... Pneumococcal disease, one of the world's leading causes of death and serious illness (1), must be recognised as an urgent global health issue together with HIV, malaria and TB, say the UK All-Party Parliamentary Group (APPG) on Pneumococcal...

American Academy of Pediatrics Celebrates 15th Anniversary of the CATCH Program.
October 27, 2008... Today, the American Academy of Pediatrics (AAP) celebrates the 15th anniversary of its Community Access to Child Health (CATCH) program during the AAP's National Convention and Exhibition in Boston. CATCH is a national AAP program designed to...

TB Alliance Enters into Collaboration with sanofi-aventis to Fight Tuberculosis.
October 27, 2008... The Global Alliance for TB Drug Development (TB Alliance) and sanofi-aventis announced that they have entered into a collaboration agreement to accelerate the discovery, development and clinical use of drugs against tuberculosis (TB). The TB...