AIDS Vaccine Week articles from November 2003

AIDS Vaccine Week archives from November 2003

Glycolytic enzyme plays key role in L-nucleoside analog efficacy.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- An enzyme crucial for the efficacy of L-nucleoside analogs has been identified. These drugs represent "a new class of clinically active antiviral and anticancer agents," scientists in the United...

Reduced NCR expression underlies NK cell dysfunction during HIV infection.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Reduced NCR expression underlies NK cell dysfunction during HIV infection "Signals leading to NK cell triggering are primarily mediated by natural cytotoxicity receptors (NCR) upon binding to...

Yeast model aids study of CCR5 activation.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- A yeast model has enabled a detailed characterization of CCR5 signaling. "CCR5 is a G protein-coupled receptor for RANTES, MIP-1alpha, MIP-1beta, and MCP-2 that functions as the front line...

Adjuvant licensed for the development of HIV vaccine.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- The Immune Response Corporation (IMNR) and Hybridon, Inc., (HYBN) have entered into a license agreement for the use of Amplivax as an adjuvant in the development of a novel vaccine candidate for the...

Gates Foundation doubles grant for India.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- The Bill and Melinda Gates Foundation says it is doubling, to $200 million, the prevention funds for HIV and AIDS that the Microsoft chairman promised India in a visit last year. The announcement...

Cancer vaccine company completes UKP 17M financing.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- BioVex, Ltd., announced the completion of a UKP 17 million (U.S. $28 million) private placement. The placement was led by Scottish Equity Partners (U.K.). Other new investors participating in the...

HLA-B22 alleles linked to rapid disease progression in white HIV patients.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- HLA-B22 alleles exert a potent influence over the course of HIV infection in white patients. "The human leukocyte antigen (HLA)-B22 serogroup - which consists of the alleles B*54, B*55, and B*56 -...

Highly virulent X4-tropic CRF02.AG HIV isolate cloned.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- A highly virulent, T-cell-tropic CRF02.AG HIV isolate from Africa has been cloned. "Based on our previous analysis of HIV-1 isolates from Cameroon," scientists in Germany "constructed a full-length...

SHIV Nef ITAM deletions linked to loss of virulence in macaques.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Deletions in the ITAM motif of simian-human immunodeficiency virus (SHIV) Nef protein cause of loss of virulence in macaques. According to published research from France, "SHIVsbg, expressing Vpu,...

FDG-PET imaging shows HIV progression.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- FDG-based positron emission tomography (PET) can be used to track HIV disease progression. FDG-PET is already known to detect "active lymphoid tissues during HIV-1 infection in man," scientists in...

Dimeric derivatives of peptide HIV integrase inhibitors show improved efficacy.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Dimeric derivatives of peptide HIV integrase inhibitors show improved efficacy over their parent agents. In a recent study from the United States, "Dimers of known HIV-1 integrase inhibitory...

Modified HIV PIs active against drug-resistant virus, but lack bioavailability.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- A series of modified HIV PIs are highly active against PI-resistant strains, but have limited bioavailability. According to published research from Merck Research Laboratories, "Transposition of...

Plasma-derived HIV should be used for drug resistance genotyping.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Plasma-derived HIV should be used for viral genotyping to determine drug resistance. "HIV-1 genotype assays using plasma viruses have been widely applied for detection of resistant viruses in...

HIV sensitivity to RANTES neutralization can mark disease progression.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- HIV sensitivity to RANTES neutralization can be used to help mark disease progression. "In approximately half of human immunodeficiency virus (HIV) type 1-infected individuals, the development of...

CSF analysis vital for diagnosis of opportunistic CNS infections in HIV patients.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- CSF analysis is vital for the diagnosis of opportunistic CNS infections in HIV patients. "In up to 50% of all human immunodeficiency virus (HIV) patients, the nervous system is clinically involved,"...

Oral epithelial cells can be infected with HIV in vitro.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Cultured oral epithelial cells are vulnerable to HIV infection. "Epithelial cells lining the oral cavity are exposed to HIV-1 through breast-feeding and oral-genital contact," scientists in the...

Some HIV-2 strains don't use normal HIV coreceptors.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Some HIV-2 strains don't use the normal HIV coreceptors for cell entry. "In vivo, human immunodeficiency virus type 2 (HIV-2) infection reveals several unique characteristics when compared to HIV-1...

Efavirenz analog binding to K103N HIV mutants determined.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- The factors that determine efavirenz analog binding to mutant HIV RT have been identified. In a recent study from the United States, "Monte Carlo-extended linear response (MC/ELR) calculations"...

Effect of blood-brain barrier on hydroxyurea elucidated.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- The effect of the blood-brain barrier on hydroxyurea pharmacokinetics has been elucidated. "Hydroxyurea is used in the treatment of HIV infection in combination with nucleoside analogues,...

Improved method for aryl beta-diketo acids developed.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- A novel oxalylation technique may lead to increased production of anti-HIV beta-diketo acids. According to published study results from China, "An improved and efficient oxalylation of aryl methyl...

Indinavir suppresses transendothelial migration of immature dendritic cells.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- The anti-HIV agent indinavir (IDV) suppresses the transendothelial migration of some immature immune cells. IDV "is a protease inhibitor that successfully suppresses HIV-1 replication as part of...

Birth order in twins has no effect on HIV transmission risk.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Contrary to previous reports, birth order in twins has no effect on HIV vertical transmission risk. In a recent study, scientists in the United States "examined birth order and delivery route as...

Murine model may aid study of opportunistic histoplasmosis.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- A novel murine model may aid research on opportunistic histoplasmosis in HIV and other immunocompromised patients. "Use of a pulmonary model of histoplasmosis in CD4/CD8 lymphocyte-depleted animals...

Novel genetic markers useful for Encephalitozoon hellem typing.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- A series of newly identified genetic markers can aid the epidemiological study of the opportunistic pathogen Encephalitozoon hellem. In a recent study from Spain, seven E. hellem isolates collected...

Valacyclovir inhibits EBV replication in HIV-associated HLP.
November 3, 2003... 2003 NOV 3 - (NewsRx.com & NewsRx.net) -- Valacyclovir can suppress EBV activity in patients with HIV-related HLP. In a recent study from the United States, "Nineteen cases of human immunodeficiency virus (HIV)-associated oral hairy...

Snake venom-derived LAO with anti-HIV activity described.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- A snake venom-derived LAO with antiretroviral activity has been described. According to recent research from China, "A novel L-amino acid oxidase, named TSV-LAO, has been purified and cloned from...

Mucosal delivery of HIV-1 Tat protein elicits strong immune response.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- Mucosal delivery of the human immunodeficiency virus-1 Tat protein in mice elicits systemic neutralizing antibodies, cytotoxic T lymphocytes, and mucosal IgA According to a study from Italy, "Human...

DCs loaded with yeast-derived HIV particles immunogenic during chronic infection.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- DCs loaded with yeast-derived HIV particles are immunogenic during chronic infection. "To evaluate the immunogenicity of human immunodeficiency virus (HIV type I p55(gag) virus-like particles...

HIV Nef does not affect the efficiency of viral cell fusion.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- The HIV Nef protein does not affect the efficiency of viral cell fusion. HIV Nef "stimulates viral infectivity by an unknown mechanism," scientists in Tennessee explained. "Recent studies have...

Drugmaker cuts costs on HIV/AIDS medications.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- GlaxoSmithKline (GSK) has reduced the not-for-profit prices of its HIV/AIDS medicines for qualifying countries and organizations. It has also extended the voluntary license granted to Aspen...

Novel gp41 crystal structure licensed from Cornell Research Foundation.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- Locus Pharmaceuticals, Inc., a privately held pharmaceutical company focused on developing small-molecule therapeutics, has licensed from Cornell Research Foundation a proprietary crystal structure of...

Antiretroviral activity of BMS-378806 characterized.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- The antiretroviral activity of BMS-378806 has been characterized. "BMS-378806 is a recently discovered small-molecule human immunodeficiency virus type I (HIV-1) attachment inhibitor with good...

Biopharmaceutical corporation plans $12 million private placement financing.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- The Immune Response Corporation (IMNR) has entered into agreements to sell, through a private placement, approximately 6 million shares of common stock at $2.02 per share to a number of unaffiliated...

Early transcription from nonintegrated HIV DNA possible.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- Nonintegrated HIV DNA is capable of early transcription. "Replication of human immunodeficiency virus (HIV) involves obligatory sequential processes. Following viral entry and reverse...

Proteins needed for MVB biogenesis involved in HIV budding.
November 10, 2003... 2003 NOV 10 - (NewsRx.com & NewsRx.net) -- Several proteins which induce MVB budding also play key roles in the release of HIV particles from infected cells. "HIV release requires TSG101, a cellular factor that sorts proteins into vesicles...

NIH-funded HIV vaccine design and development team in place.
November 17, 2003... 2003 NOV 17 - (NewsRx.com & NewsRx.net) -- The U.S. National Institutes of Health (NIH) has awarded a $19 million, 5-year grant for HIV vaccine development grant to Novavax, Inc., along with partners at Emory University School of Medicine and...

Drosophila aids study of HIV Vpu activity.
November 17, 2003... 2003 NOV 17 - (NewsRx.com & NewsRx.net) -- A fruit fly model can aid the study of the HIV Vpu protein and its immunomodulatory effects. "Human immunodeficiency virus 1 (HIV-1) expresses several accessory proteins that manipulate various...

Modified liposomes improve lentiviral transfection of lymphocytes.
November 17, 2003... 2003 NOV 17 - (NewsRx.com & NewsRx.net) -- Novel liposomes improve the efficiency of lentiviral-based gene therapy targeting lymphocytes. "Circulating lymphocytes are important target cells for the treatment of HIV-related and autoimmune...

Exogenous IL-2 improves proliferation of HIV-specific CD4 cells.
November 17, 2003... 2003 NOV 17 - (NewsRx.com & NewsRx.net) -- Low IL-2 production is linked to impaired proliferation of HIV-specific CD4 cells, which can be reversed by treatment with exogenous IL-2. "Virus-specific CD4+ T-cell function is thought to play a...

Intracellular HMGB1 blocks HIV LTR-mediated transcription in some cells.
November 17, 2003... 2003 NOV 17 - (NewsRx.com & NewsRx.net) -- Intracellular HMGB1 blocks HIV LTR-mediated transcription in some cells. In a recent study, scientists in New York "investigated whether the high mobility group B1 (HMGB1), an abundant nuclear...

Structure of dimerized NFAT1 bound to HIV LTR kappa B clarified.
November 17, 2003... 2003 NOV 17 - (NewsRx.com & NewsRx.net) -- The structure of dimerized NFAT1 bound to a key site in the HIV promoter has been elucidated. "DNA binding by NFAT1 as a dimer has been implicated in the activation of host and viral genes,"...

Anti-HIV agents derived from Petrosia sponge.
November 17, 2003... 2003 NOV 17 - (NewsRx.com & NewsRx.net) -- Anti-HIV agents have been isolated from a Petrosia sponge. According to a recent study from India, the "marine sponge Petrosia similis afforded two compounds which belongs to bis-quinolizidine...

Improved AZT derivatives developed.
November 17, 2003... 2003 NOV 17 - (NewsRx.com & NewsRx.net) -- A series of AZT derivatives show promise as antiretroviral agents. In a recent study from France, "The synthesis and in vitro anti-HIV activity of phosphoramidate diester derivatives of...

Peptide analogs may aid study of retroviral-induced immunosuppression.
November 17, 2003... 2003 NOV 17 - (NewsRx.com & NewsRx.net) -- A pair of retroviral peptide analogs may aid research on virus-induced immune suppression. "The mechanism by which retroviral proteins exert their immunosuppressive influence has remained...

Pharmacophore model predicts anti-HIV CCR5 antagonist activity.
November 17, 2003... 2003 NOV 17 - (NewsRx.com & NewsRx.net) -- A novel molecular model can be used to predict the activity of CCR5 antagonists prior to synthesis. According to published research from the United States, "Predictive pharmacophore models were...

Promising small peptide HIV RT inhibitor designed.
November 17, 2003... 2003 NOV 17 - (NewsRx.com & NewsRx.net) -- A promising small peptide HIV RT inhibitor has been designed. "A crucial step in the replication of HIV-1 is the conversion of its single-stranded RNA to double-stranded DNA, which is catalyzed by...

Recombinant CD154 can reactivate latent HIV infection.
November 17, 2003... 2003 NOV 17 - (NewsRx.com & NewsRx.net) -- A recombinant form of CD154 may be useful for reactivating latent HIV infection. "Reservoirs of latent HIV-1 in T cells and macrophages pose one of the major obstacles that hamper final eradication...

HIV-based vectors do not disrupt cellular transcription.
November 17, 2003... 2003 NOV 17 - (NewsRx.com & NewsRx.net) -- HIV-based gene therapy should not disrupt normal cellular gene transcription. In a recent study, scientists in California "examined the changes in cellular transcription resulting from infection...

Genetic recombination between R5 and X4 HIV strains occurs in vivo.
November 17, 2003... 2003 NOV 17 - (NewsRx.com & NewsRx.net) -- In vivo genetic recombination between X4 and R5 strains of HIV has been reported. "Human immunodeficiency virus type 1 (HIV-1) infection is in general established by CCR5-utilizing (R5) virus...

HIV gene transcription reviewed.
November 17, 2003... 2003 NOV 17 - (NewsRx.com & NewsRx.net) -- The process of HIV gene transcription during infection has been reviewed. "Transcription from the HIV genome is regulated by the 5' long-terminal-repeat viral promoter as well as regulatory...

HIV Nef plays key role in virus-induced podocyte dedifferentiation.
November 17, 2003... 2003 NOV 17 - (NewsRx.com & NewsRx.net) -- The HIV Nef protein plays a key role in virus-induced podocyte dedifferentiation. According to published research from the United States, "The notable glomerular feature of human immunodeficiency...

HIV Tat induces cerebral inflammation and monocyte invasion.
November 17, 2003... 2003 NOV 17 - (NewsRx.com & NewsRx.net) -- HIV Tat can induce cerebral inflammation resulting in monocyte invasion. "Impaired inflammatory functions may be critical factors in the mechanisms by which HIV-1 enters the CNS," scientists in the...

HIV protease inhibitors increase cellular 2-DG transport.
November 17, 2003... 2003 NOV 17 - (NewsRx.com & NewsRx.net) -- HIV protease inhibitors significantly alter cellular 2-DG transport. Scientists in Canada conducted a study "to investigate the long-term effects of antiretroviral protease inhibitors (PIs) on...

HIV Rev binds specifically to SL1 purine loop in viral leader RNA.
November 17, 2003... 2003 NOV 17 - (NewsRx.com & NewsRx.net) -- The HIV Rev protein binds specifically to a purine loop located in the SL1 region of viral leader RNA. According to published research from England, "The leader RNA sequence of human...

HIV terminal exon splicing silencer function clarified.
November 17, 2003... 2003 NOV 17 - (NewsRx.com & NewsRx.net) -- The activity of an HIV exon splicing silencer has been characterized. "The control of HIV-1 viral RNA splicing and transport plays an important role in the successful replication of the virus,"...

Treatment with multiple small interfering RNAs augments gene silencing.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- The use of multiple small interfering RNAs (siRNAs) can augment gene silencing in transfected cells. According to scientists in Switzerland, siRNAs "induce gene silencing in various eukaryotic...

New gene-based approaches for AIDS vaccine reviewed.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- Researchers have reviewed new gene-based approaches for an AIDS vaccine in a recent issue of the journal Comparative Immunology, Microbiology, and Infectious Diseases. According to recent research...

G-quartets direct HIV nucleocapsid protein assembly along single-stranded DNA.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- G-quartets direct HIV nucleocapsid protein assembly along single-stranded DNA. According to a study from France, "The d(TTGGGGGGTACAGTGCA) sequence, derived from the human immunodeficiency virus...

New approaches in vaccine development reviewed.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- A researcher has reviewed the latest progress in new approaches to vaccine development in a recent issue of Comparative Immunology, Microbiology, and Infectious Diseases. "In the last century,...

Human trial of HIV vaccine in South Africa under way.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- Researchers have begun testing an experimental HIV vaccine on 24 human volunteers in South Africa, a country where more than 1 in 10 people is infected with the AIDS-causing virus. The treatment,...

NewsRx wins 2003 eHealthcare Leadership awards.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- NewsRx, a leader in professional health publishing and databases, won top honors in the 2003 eHealthcare Leadership Awards. The company was recognized for its Internet excellence at a recent...

Easily generated HIV protease inhibitors derived from carbohydrate alditols identified.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- A novel series of easily generated antiretroviral agents has been identified. Scientists in Canada evaluated "the synthesis and structure-activity relationships of HIV protease inhibitors derived...

HIV Tat-TAR RNA antagonist strongly inhibits replication in vitro.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- A novel HIV Tat-TAR antagonist strongly inhibits viral replication in vitro. "Antiretroviral therapy to treat AIDS uses molecules that target the reverse transcriptase and protease enzymes of human...

Novel HIV protease inhibitor effective against PI-resistant strains in vitro.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- A recently developed HIV PI is highly active against PI-resistant viral strains in vitro. Scientists in Japan "designed, synthesized, and identified UIC-94017 (TMC114), a novel nonpeptidic human...

Pyridine oxide derivatives have dual-mode anti-HIV activity.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- A novel class of antiretroviral agents possesses dual-mode activity against HIV. In a recent study, scientists in Belgium found that "novel pyridine oxide derivatives are inhibitors of a wide range...

CTL epitope specificity determines extent of HIV suppression.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- CTL epitope specificity determines the extent of their anti-HIV activity. "Although CD8+ CTLs are presumed to be an important mediator of protective immunity in HIV-1 infection, the factors that...

Thiamine supplements may help prevent HIV-related Wernicke encephalopathy.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- Thiamine supplements may help prevent HIV-related Wernicke encephalopathy. "Wernicke encephalopathy is commonly associated with chronic alcohol abuse, but may also occur in patients with poor...

CCL2 may play key role in virion production by HIV-infected cells.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- CCL2 may play a key role in virion production by HIV-infected cells. "CC chemokine ligand 2 (CCL2) is constitutively expressed at high levels in human peripheral blood monocytes, and its expression...

Epstein-Barr virus infection may increase T-cell susceptibility to HIV.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- Epstein-Barr virus (EBV) infection may increase the vulnerability of T cells to HIV invasion. According to virologists in Japan, EBV "is an important pathogen in human immunodeficiency virus...

HIV Vif disrupts APOBEC3G translation and intracellular stability.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- The HIV Vif protein disrupts APOBEC3G translation and intracellular stability. "The human immunodeficiency virus type 1 (HIV-1) relies on Vif (viral infectivity factor) to overcome the potent...

HAART lowers levels of HIV-enhancing antibodies.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- HAART reduces levels of HIV-enhancing antibodies in treated patients. In a recent study, scientists in Hungary examined "the effect of highly active antiretroviral therapy (HAART) on balance of the...

High-dose oral hydroxyurea produces effective CSF drug levels.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- High-dose oral hydroxyurea treatment produces effective CSF levels of the drug. "Hydroxyurea has been shown to potentiate the activity of the antiretroviral nucleoside analogs," scientists in the...

Nadir CD4 cell count in HIV patients predicts response to subcutaneous rIL-2 treatment.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- Nadir CD4 cell count in HIV patients predicts their response to subcutaneous rIL-2 treatment. According to published research from the United States, "Community Program for Clinical Research on...

Structured HIV treatment interruptions have no impact on salvage regimen efficacy.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- The STI strategy does not improve the antiretroviral activity of salvage therapy for HIV patients. In a recent study, scientists in Spain "evaluated the efficacy of a five-drug salvage regimen,...

Visceral leishmaniasis rate in HIV patients dropped after HAART introduction.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- The risk of visceral leishmaniasis in HIV patients has dropped since the introduction of HAART. In a recent study, scientists in Spain examined "the effect of highly active antiretroviral therapy...

Apical loop of HIV TAR RNA hairpin characterized.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- The apical loop of the HIV transactivation response element (TAR) RNA hairpin has been elucidated. "The TAR hairpin of the HIV-1 RNA genome is indispensable for transactivation of the viral...

Computerized reminder system improves Pap smear compliance at HIV clinic.
November 24, 2003... 2003 NOV 24 - (NewsRx.com & NewsRx.net) -- A computerized reminder system may improve Pap smear compliance for women receiving treatment at HIV care centers. According to published research from New York, "Current guidelines call for...