AIDS Vaccine Week articles from January 2009

AIDS Vaccine Week archives from January 2009

Data from S.P. Buchbinder and colleagues advance knowledge in HIV/AIDS.(Clinical report)
January 5, 2009... According to recent research from the United States, " Observational data and non-human primate challenge studies suggest that cell-mediated immune responses might provide control of HIV replication. The Step Study directly assessed the...

Data on HIV/AIDS described by M.L. Precopio et al.
January 5, 2009... According to a study from the United States, "Mapping T-cell epitopes for a pathogen or vaccine requires a complex method for screening hundreds to thousands of peptides with a limited amount of donor sample. We describe an optimized...

New HIV/AIDS study findings recently were reported by researchers at McMaster University.
January 5, 2009... "The membrane-proximal external region (MPER) of the gp41 fusion protein of HIV is highly conserved among isolates of this virus and is considered a target for vaccine development. This region also appears to play a role in membrane fusion as...

New HIV/AIDS study results reported from M.J. Mcelrath et al.
January 5, 2009... " In the Step Study, the MRKAd5 HIV-1 gag/pol/nef vaccine did not reduce plasma viraemia after infection, and HIV-1 incidence was higher in vaccine-treated than in placebo-treated men with pre-existing adenovirus serotype 5 (ALIS) immunity. We...

Recent studies from University of California add new data to HIV/AIDS.
January 5, 2009... "Human immunodeficiency virus (HIV) infection leads to severe CD4+ T-cell depletion in gut-associated lymphoid tissue (GALT) that persists despite the initiation of highly active antiretroviral therapy (HAART). It is not known whether...

Recent studies from University of Wisconsin add new data to HIV/AIDS.
January 5, 2009... According to a study from the United States, "An effective AIDS vaccine will need to protect against globally diverse isolates of HIV. To address this issue in macaques, we administered a live-attenuated simian immunodeficiency virus (SIV)...

National Institutes of Health publishes research in life sciences.
January 5, 2009... According to recent research published in the journal Proceedings of the National Academy of Sciences of the United States of America, "Toll-like receptors (TLRs) may need to cooperate with each other to be effective in detecting imminent...

Scientists at Swedish Institute for Infectious Disease Control release new data on HIV/AIDS vaccines.
January 5, 2009... A report, 'CTA1-DD adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization,' is newly published data in The Journal of General Virology. According to recent research...

ImQuest Presentations at International HIV Meeting Highlight Significant Progress in Their Therapeutic and Microbicide Development Programs.
January 5, 2009... ImQuest Life Sciences presented important new results on the continued development of their small molecule pyrimidinedione inhibitors of HIV-1 at the bi-annual HIV-DART meeting held this week in Puerto Rico. The presentations highlighted the...

The International AIDS Vaccine Initiative Posts $150,000 Challenge on InnoCentive in Search of New Approaches to AIDS Vaccine Design.
January 5, 2009... InnoCentive, Inc., the global innovation marketplace, announced that the International AIDS Vaccine Initiative (IAVI), a global not-for-profit organization whose mission is to ensure the development of safe, effective, accessible, preventive...

Research from University of Nebraska has provided new information about HIV/AIDS.
January 12, 2009... According to a study from the United States, "Selection of a minor viral genotype during perinatal transmission of human Immunodeficiency virus type 1 (HIV-1) has been observed, but there is a lack of information on the correlation of the...

Research reports on HIV/AIDS from E.K. Quirk and colleagues provide new insights.
January 12, 2009... According to recent research from the United States, "We analyzed human immunodeficiency virus (HIV) seroresponses from 3 phase 1 HIV-1 vaccine trials to assess the frequency of vaccine-induced seroconversion. HIV-1 and HIV-2 enzyme-linked...

Researchers from Department of Agriculture describe findings in veterinary immunopathology.
January 12, 2009... According to recent research from the United States, "Previous studies using F1 reciprocal crosses and two parental lines of broilers show the sire is instrumental in determining the ill vitro leukocyte function and cytokine/chemokine profile....

Scientists at University of Michigan release new data on HIV/AIDS.
January 12, 2009... According to recent research published in the journal Biometrics, "Grouped failure time data arise often in HIV studies. In a recent preventive HIV vaccine efficacy trial, immune responses generated by the vaccine were measured from a...

Data on immunization reported by researchers at University of New South Wales.
January 12, 2009... According to recent research published in the Journal of Virology, "The dynamics of HIV infection have been studied in humans and in a variety of animal models. The standard model of infection has been used to estimate the basic reproductive...

Findings from University of Washington provide new insights into life sciences.
January 12, 2009... "Frangakis and Rubin (2002, Biometrics 58, 21-29) proposed a new definition of a surrogate end-point (a ''principal'' surrogate) based on causal effects. We introduce an estimand for evaluating a principal surrogate, the causal effect...

'Sharing Miracles' Television Program to Feature Country Music Superstar and Grammy Winner Naomi Judd.
January 12, 2009... Each Sunday throughout January, Sharing Miracles, a 30-minute public affairs television program that tells the compelling and inspirational stories of real patients, will feature country music superstar and six-time Grammy Award winner Naomi...

Hard To Treat Diseases (HTDS) Pending Merger Update.
January 12, 2009... Hard to Treat Diseases (HTDS) www.htdsmedical.com Further to the company's news release of December 30, 2008 where amongst other things the company addressed the targeted merger candidate, firstly the company is pleased to announce that it has...

Reports from University of Arizona describe recent advances in drug resistance.
January 19, 2009... "Many of the greatest challenges in medicine and public health involve the evolution of drug resistance by pathogens. Recent advances in the theory of natural selection suggest that there are two broad classes of pathogen traits that can be...

Data on HIV/AIDS discussed by researchers at University of Geneva, Medical Department.
January 19, 2009... According to recent research published in the Jaids - Journal of Acquired Immune Deficiency Syndromes, "New prevention strategies are urgently needed to slow the spread of the HIV/AIDS pandemic, and in the absence of an effective vaccine, there...

New HIV/AIDS research from K. Mayer et al outlined.
January 19, 2009... According to a study from the United States, "The reasons that epidemics occur largely are a function of human behaviors and responses to environmental changes, known as the social ecology of infectious diseases. The AIDS epidemic began in...

New HIV/AIDS study findings recently were reported by researchers at Columbia University.
January 19, 2009... "Given the ethical controversies concerning HIV vaccine trials (HVTs), we aimed to understand through an exploratory study how members of institutional review boards (IRBs) in the United States (US) and research ethics committees (RECs) in...

Research data from A. Cagigi and colleagues update understanding of HIV/AIDS.
January 19, 2009... "HIV-1 infection is associated with B-cell abnormalities, such as hypergamma-globulinemia, poor immunization responses, and loss of serologic memory. To determine whether altered expression of chemokine receptors and their ligands may play a...

Studies in the area of HIV/AIDS reported from Indiana University.(Report)
January 19, 2009... According to a study from the United States, "A previous study (Goh G.K.-M., Dunker A.K., Uversky V.N. (2008) Protein intrinsic disorder toolbox for comparative analysis of viral proteins. BMC Genomics. 9 (Suppl. 2), S4) revealed that HIV...

Reports from Karolinska Institut add new data to research in HIV/AIDS vaccines.(Report)
January 19, 2009... Current study results from the report, 'Maternal immune status influences HIV-specific immune responses in pups after DNA prime protein boost using mucosal adjuvant,' have been published. According to recent research from Solna, Sweden, "This...

Researchers at University of the Basque Country publish new data on HIV/AIDS vaccines.
January 19, 2009... A new study, 'Lipid modulation of membrane-bound epitope recognition and blocking by HIV-1 neutralizing antibodies,' is now available. According to recent research published in the journal FEBS Letters, "The conserved, aromatic-rich...

ImQuest Submits Investigational New Product Application to the Food and Drug Administration to Initiate HIV Therapeutic Clinical Trials with IQP-0410.
January 19, 2009... ImQuest Life Sciences announced the successful submission of an IND application to the Food and Drug Administration to initiate human clinical trials for their lead pyrimidinedione HIV inhibitor IQP-0410. ImQuest anticipates initiating their...

Learn about the World HIV/AIDS Testing Market.
January 19, 2009... Reportlinker.com announces that a new market research report related to the Diagnostic equipment industry is available in its catalogue. World HIV/AIDS Testing Market http://www.reportlinker.com/p098402/World-HIV/AIDS-Testing--Market.html This...

Researchers from Harvard University publish new studies and findings in the area of adenovirus.
January 26, 2009... "A recombinant adenovirus serotype 5 ( rAd5) vector- based vaccine for HIV-1 has recently failed in a phase 2b efficacy study in humans(1,2). Consistent with these results, preclinical studies have demonstrated that rAd5 vectors expressing...

Reports from University of Utah, Medical Department highlight recent research in HIV/AIDS.
January 26, 2009... According to recent research from the United States, "During viral entry, HIV gp41 adopts a transient conformation called the ''prehairpin intermediate'' in which a highly conserved therapeutic target, the N-trimer, is exposed. Despite...

Research from C.A. Blish et al has provided new information about HIV/AIDS.(Report)
January 26, 2009... "Superinfection by a second human immunodeficiency virus type 1 (HIV-1) strain indicates that gaps in protective immunity occur during natural infection. To define the role of HIV-1-specific neutralizing antibodies (NAbs) in this setting, we...

Researchers from University of California publish findings in HIV/AIDS.
January 26, 2009... "The recently failed clinical efficacy trial of an acquired immunodeficiency syndrome (AIDS) vaccine that elicits antiviral CD8(+) T-cell responses has emphasized the challenge of producing an effective vaccine against human immunodeficiency...

Study results from A. Forsman et al provide new insights into HIV/AIDS.
January 26, 2009... According to recent research published in the Journal of Virology, "Members of the Camelidae family produce immunoglobulins devoid of light chains. We have characterized variable domains of these heavy chain antibodies, the VHH, from llamas...

Research from K.M. Roy and colleagues has provided new data on immunization.
January 26, 2009... According to recent research from Scotland, "Background and Aims The United Kingdom has adopted a selective approach to the control of hepatitis B (HBV), vaccinating those at increased risk of infection through lifestyle, occupation or other...

Studies from Catholic University in the area of immunization described.
January 26, 2009... According to recent research from Seoul, South Korea, "Carcinoembryonic antigen (CEA) is expressed on human colon carcinomas, is well characterized, and continues to be a promising target for cancer immunotherapy in humans. To enhance the in...

Studies from Huazhong Agricultural University yield new data on HIV/AIDS.
January 26, 2009... Investigators publish new data in the report 'Generation and characterization of an H5N1 avian influenza virus hemagglutinin glycoprotein pseudotyped lentivirus.' "An H5N1 avian influenza virus (AIV) hemagglutinin (HA) protein pseudotyped...

Studies from National Institute for Communicable Diseases further understanding of pneumococcal disease vaccines.(Report)
January 26, 2009... New investigation results, 'Serotype 6C is associated with penicillin-susceptible meningeal infections in human immunodeficiency virus (HIV)-infected adults among invasive pneumococcal isolates previously identified as serotype 6A in South...