AIDS Vaccine Week articles from December 2008

AIDS Vaccine Week archives from December 2008

Reports from University of Liege describe recent advances in enzyme research.
December 1, 2008... According to recent research published in the Febs Journal, "Insertion of heterologous peptide sequences into a protein carrier may impose structural constraints that could help the peptide to adopt a proper fold. This concept could be the...

New HIV/AIDS study findings have been reported from A. Piantadosi et al.(Report)
December 1, 2008... According to recent research from the United States, "HIV-1 superinfection may occur at a rate similar to that of initial infection, raising concerns for HIV-1 vaccine strategies predicated on eliciting immune responses similar to those in...

Studies from S. Kulkarni et al further understanding of HIV/AIDS.
December 1, 2008... According to recent research from Pune, India, "The longitudinal heterologous neutralization response against two HIV-1 subtype C isolates was studied in 33 ART-naive individuals recently infected with HIV-1 subtype C from India. Seven of 33...

Study results from Case Western Reserve University, Medical Department update understanding of HIV/AIDS.
December 1, 2008... "Our understanding of how CD4(+) T cells can regulate CD8(+) T cell responses in HIV infection is still incomplete. Recent evidence obtained in mice suggests that CD4(+) T cell help is required for efficient CD8(+) T cell-mediated immunity in...

New HIV/AIDS clinical trial study findings recently were reported by researchers at Columbia University, Department of Medicine.(Clinical report)
December 1, 2008... Research findings, 'Vaginal microbicides and the prevention of HIV transmission,' are discussed in a new report. According to a study from the United States, "Worldwide, nearly half of all individuals living with HIV are now women, who acquire...

New HIV/AIDS vaccines study findings have been reported by E. Sandstrom and co-researchers.
December 1, 2008... Investigators publish new data in the report 'Broad immunogenicity of a multigene, multiclade HIV-1 DNA vaccine boosted with heterologous HIV-1 recombinant modified vaccinia virus Ankara.' According to recent research from Sweden, "A human...

Study findings from Centers for Disease Control and Prevention provide new insights into immunization.(Report)
December 1, 2008... New research, 'Evaluation of the immune response to a 2-dose measles vaccination schedule administered at 6 and 9 months of age to HIV-infected and HIV-uninfected children in Malawi,' is the subject of a report. "The World Health Organization...

Bavarian Nordic Receives USD 25 Million Milestone Payment After Submission of Important IMVAMUNE(R) Data to the U.S. Health Authorities.
December 1, 2008... Bavarian Nordic has invoiced the U.S. authorities for another milestone payment of USD 25 million as allowed under the RFP-3 contract to manufacture and deliver 20 million doses of the company's IMVAMUNE(R) smallpox vaccine. This milestone...

Important Message for 2008 Universal Children's Day.
December 1, 2008... Calling the daily preventable deaths of 25,000 children worldwide 'profoundly shameful and unnecessary', the U.S. Fund for UNICEF today marked Universal Children's Day by launching "Believe in Zero", a campaign that encourages policy makers...

Sabin Vaccine Institute Elects Morton P. Hyman Chairman.
December 1, 2008... The Sabin Vaccine Institute (Sabin) announced the election of Morton P. Hyman as its new Chairman; he joined the Board of Trustees in 2007. He succeeds long time trustee, chairman and founding president, Philip K. Russell, MD, who has been...

Study findings from National Institutes of Health broaden understanding of Escherichia coli.
December 8, 2008... According to recent research published in the journal Biotechnology and Bioengineering, "Plasmid DNA (pDNA) is an emerging experimental vaccine, Produced in E. coli, initially targeted for viral diseases. Unlike traditional protein vaccines...

Studies from Institute of Biology yield new data on HIV/AIDS immunology.
December 8, 2008... A new study, 'Immunoprevalence of the CD4+ T-cell response to HIV Tat and Vpr proteins is provided by clustered and disperse epitopes, respectively,' is now available. "Recent studies have suggested including nonstructural proteins as Tat and...

EpiVax Receives NIH Grant for $390,000 to Optimize HIV Vaccine Delivery.
December 8, 2008... EpiVax, Inc., a leader in the field of computational immunology, announced that it has received a grant from the National Institute of Allergy and Infectious Diseases (NIAID), a division of the National Institutes of Health (NIH), to optimize...

Data Published in Nature Medicine Highlights Ability of Peregrine Pharmaceuticals' Bavituximab to Cure Lethal Virus Infections.
December 8, 2008... Peregrine Pharmaceuticals, Inc. (NASDAQ:PPHM) reported publication of data in Nature Medicine that supports the broad anti-viral potential of the company's novel anti-phosphatidylserine (anti-PS) antibody platform, showing that its PS-targeting...

M*A*C AIDS Fund Bolsters South Africa HIV Care, Prevention with $2.5 Million USD.
December 8, 2008... A new grant program from the M*A*C AIDS Fund has gifted $2.5 million to fight HIV and AIDS in South Africa. The grant will go to UNICEF South Africa and Nurturing Orphans of AIDS for Humanity (NOAH) to fund testing and treatment for pregnant...

Stanford scientists' discovery of virus in lemur could shed light on AIDS.(Report)
December 15, 2008... The genome of a squirrel-sized, saucer-eyed lemur from Madagascar may help scientists understand how HIV-like viruses coevolved with primates, according to new research from the Stanford University School of Medicine. The discovery, to be...

Research in the area of HIV/AIDS reported from University of Frankfurt.
December 15, 2008... According to a study from Frankfurt, Germany, "Our paper measures the prevalence of hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) in patients at the University Hospital of Frankfurt/Main, and correlates...

Study results from University of Manitoba provide new insights into HIV/AIDS.(Report)
December 15, 2008... According to recent research from Winnipeg, Canada, "Novel tools are necessary to understand mechanisms of altered susceptibility to HIV-1 infection in women of the Pumwani Sex Worker cohort, Kenya. In this cohort, more than 140 of the 2000...

New HIV/AIDS vaccines study results from Centers for Disease Control and Prevention described.
December 15, 2008... New investigation results, 'Effectiveness of 23-valent polysaccharide pneumococcal vaccine on pneumonia in HIV-infected adults in the United States, 1998--2003,' are detailed in a study published in Vaccine. "Pneumococcal polysaccharide vaccine...

Jolie-Pitt Foundation Awards Second Grant to Global Action for Children.
December 15, 2008... Today, Global Action for Children (GAC) announced a $100,000 end-of-year-grant from the Jolie-Pitt Foundation. The grant will support GAC's efforts on an Emergency Presidential Initiative for the World's Children (EPIWC) in the new Obama...

109 Medicines and Vaccines Now in Development for HIV/AIDS.
December 15, 2008... America's pharmaceutical research companies are testing 109 medicines and vaccines to treat or prevent HIV/AIDS and related conditions, according to a report released by the Pharmaceutical Research and Manufacturers of America (PhRMA). December...

GeoVax's Phase 2a HIV/AIDS Vaccine Human Trials to Begin in North and South America.
December 15, 2008... GeoVax Labs, Inc. (BULLETIN BOARD: GOVX) , an Atlanta-based biotechnology company developing human vaccines for diseases caused by HIV-1 (Human Immunodeficiency Virus) and other infectious agents, announced that the launch of its Phase 2a Human...

Blocking immune inhibitor improves response to HIV-like virus, prolongs survival in monkeys.
December 22, 2008... By blocking PD-1 (programmed death-1), an immune receptor molecule known to inhibit the immune response to chronic viral infections, scientists have safely and significantly reduced the plasma viral load and also prolonged survival of rhesus...

Extraordinary immune cells may hold the key to managing HIV.
December 22, 2008... People who manage to control HIV on their own are providing scientists with valuable information about how the immune system eliminates virus-infected cells. A new study, published in the December 4th issue of Immunity, a Cell Press...

Reports from University of California advance knowledge in HIV/AIDS.
December 22, 2008... "Tuberculosis is the leading cause of death in AIDS patients, yet the current tuberculosis vaccine, Mycobacterium bovis bacillus Calmette-Guerin (BCG), is contraindicated for immunocompromised individuals, including human immunodeficiency...

Research on HIV/AIDS described by scientists at University of Mississippi Medical Center.
December 22, 2008... According to recent research from the United States, "Human immunodeficiency virus (HIV)-infected patients have an increased rate of pneumococcal infections. Within the HIV-infected population, patients with low CD4(+) cell counts have a higher...

Researchers at INSERM have published new data on HIV/AIDS.
December 22, 2008... According to recent research from Marseille, France, "The HIV-1 Tat protein is a promising target to develop AIDS therapies, particularly vaccines, due to its extracellular role that protects HIV-1-infected cells from the immune system. Tat...

Studies from P. Borrego et al add new findings in the area of HIV/AIDS.(Report)
December 22, 2008... According to a study from Lisbon, Portugal, "This study was designed to investigate, for the first time, the short-term molecular evolution of the HIV-2 C2, V3 and C3 envelope regions and its association with the immune response. Clonal...

New immunodeficiency study findings have been reported from University of Glasgow.
December 22, 2008... According to a study from Scotland, "Feline immunodeficiency virus (FIV) targets helper T cells by attachment of the envelope glycoprotein (Env) to CD134, a subsequent interaction with CXCR4 then facilitating the process of viral entry. As the...

Study findings from University of Tokyo provide new insights into simian immunodeficiency virus.
December 22, 2008... "Gag-specific cytotoxic T lymphocytes (CTLs) exert strong suppressive pressure on human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) replication. However, it has remained unclear whether they can actually contain primary...

Studies from Children's Hospital in the area of HIV/AIDS in children described.
December 22, 2008... Investigators publish new data in the report 'Bacillus Calmette-Guerin (BCG) vaccine-induced complications in children treated with highly active antiretroviral therapy.' According to a study from Cape Town, South Africa, "To describe the...

Researchers at University of Florida, Health Science Center publish new data on immunization.
December 22, 2008... A new study, 'Hepatitis B vaccine: a seven-year study of adherence to the immunization guidelines and efficacy in HIV-1-positive adults,' is now available. According to recent research published in the International Journal of Infectious...

Two New Studies in the New England Journal of Medicine Show Malaria Vaccine Candidate Advancing in Africa.
December 22, 2008... Results published online today in the New England Journal of Medicine revealed that the world's most clinically advanced malaria vaccine candidate provides both infants and young children with significant protection against malaria. Two...

Well-armed immune cells help long-term nonprogressors contain HIV.(Report)
December 22, 2008... To help develop an effective HIV vaccine, researchers are trying to better understand how the immune systems of a small minority of HIV-infected people known as long-term non-progressors (LTNPs) contain the virus naturally. CD8+ T cells, which...

Study offers insights about development of the human immune system.
December 22, 2008... A UCSF study has found that a surprisingly high number of maternal cells enters the fetus during pregnancy, prompting the generation of special immune cells in the fetus that suppress a response against the mother (see also University of...

Research from J.G. Joyce and colleagues provide new insights into HIV/AIDS.
December 29, 2008... According to recent research published in the journal Proceedings of the National Academy of Sciences of the United States of America, "The conserved oligomannose epitope, Man(9)GlcNAC(2), recognized by the broadly neutralizing human mAb 2G12...

Scientists at Institute for Viral Disease Control and Prevention target HIV/AIDS vaccines.
December 29, 2008... A report, 'Potent specific immune responses induced by prime-boost-boost strategies based on DNA, adenovirus, and Sendai virus vectors expressing gag gene of Chinese HIV-1 subtype B,' is newly published data in Vaccine. According to recent...

Researchers from Imperial College London, Department of Paediatrics describe findings in tuberculosis therapy.(Report)
December 29, 2008... Research findings, 'Perinatal tuberculosis: new challenges in the diagnosis and treatment of tuberculosis in infants and the newborn,' are discussed in a new report. "With increasing rates of tuberculosis (TB) infection and disease worldwide,...

Research from Biological Mimetics, Inc. has provided new data on vaccines.
December 29, 2008... A report, 'Deceptive imprinting and immune refocusing in vaccine design,' is newly published data in Vaccine. According to a study from the United States, "A large number of the world's most widespread and problematic pathogens evade host...

Beating the Number-One Killer in AIDS: Tuberculosis.
December 29, 2008... The success of treating HIV/AIDS with antiretroviral therapy has been a good news, bad news proposition. Individuals with HIV and AIDS are living longer due to the success of antiretroviral therapies. While these agents u of which more than...

Inaugural Back of the Envelope Awards fund creative health research.
December 29, 2008... Can a succinct idea written on the back of an envelope have the spark of research genius? Certainly, said UAB School of Public Health (SOPH) Dean Max Michael, M.D., talking about the origins of the inaugural Back of the Envelope Awards, a seed...

Merck Announces FDA Acceptance of Supplemental New Drug Application for ISENTRESS[R] raltegravir in Adult Patients Previously Untreated for HIV-1.
December 29, 2008... Merck & Co., Inc. announced that the U.S. Food and Drug Administration (FDA) has accepted the supplemental New Drug Application (sNDA) filing for ISENTRESS[R] (raltegravir) Tablets for standard review. The Company is seeking United States...