Drug Week articles from November 2004

Drug Week archives from November 2004

Study documents adverse events of pneumococcal vaccine in children.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Examination of reports from the first 2 years after licensure of a new vaccine against pneumococcal infections indicates that the majority of adverse effects are minor, but that continued surveillance...

Statistically significant positive phase II data reported on Cetrorelix.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- AEterna Zentaris, Inc., (AEZ; AEZS) announced statistically significant positive results from a randomized, double-blind, placebo-controlled phase II trial designed to evaluate different dosage regimens...

Positive phase II data reported for Alequel.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Enzo Biochem, Inc., (ENZ) announced that the phase II, randomized, double-blind study of Alequel, the company's investigational therapeutic modality for the management of Crohn disease, successfully met...

Study: Fuzeon plus active boosted PI doubles long-term response.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Twice as many treatment-experienced patients who used Fuzeon (enfuvirtide) with an active boosted protease inhibitor (PI) regimen experienced a significant virologic response when compared to patients...

SERM+ teriparatide offers improved bone therapy for postmenopausal patients.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- The combination of teriparatide (Forteo; Eli Lilly & Co.), an injectable parathryoid hormone medication, when administered with the selective estrogen receptor modulator, raloxifene (Evista; Eli Lilly &...

HIV-1 superinfections assessed by autologous heteroduplex mobility.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Scientists have assessed HIV-1 superinfections in a cohort of commercial sex workers in Burkina Faso by an autologous heteroduplex mobility procedure. In a recently published article, scientists in...

Current state of HIV and AIDS in Sub-Saharan Africa reviewed.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Researchers review the current state of AIDS and HIV in Sub-Saharan Africa in a recent issue of the Croatian Medical Journal. According to a study from Malawi and the United States, "Sub-Saharan...

HIV-1 immunogen vaccine plus antiretrovirals promotes virologic control.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Therapeutic immunization with an inactivated HIV-1 immunogen plus antiretrovirals promotes virologic control in asymptomatic HIV-infected subjects. According to a study from Spain, "To determine...

Estrogen protects male rats from aneurysm.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- When it comes to abdominal aortic aneurysms - life-threatening bulges or weak areas in the main artery feeding blood to the lower half of the body - it is definitely better to be female. During...

Multiresistant Acinetobacter baumannii outbreak occurred in surgical room.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Multi-resistant Acinetobacter baumannii outbreak occurred in a surgical room in Germany. "Outbreaks of Acinetobacter baumannii demonstrating multiple antibiotic resistance, including meropenem...

Phase II study of zileuton for moderate-to-severe acne begins.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Critical Therapeutics, Inc., (CRTX), a biopharmaceutical company focused on the discovery, development, and commercialization of products for respiratory, inflammatory, and critical care diseases,...

Loss of clone with FLT3 gene mutation at relapse does not improve AML prognosis.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- The loss of a clone with an FLT3 gene mutation at relapse does not improve the prognosis of acute myeloid leukemia. According to recent research from Germany, "Internal tandem duplications (ITDs)...

Genetic profiling links key genes to alcohol-related expectancies.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Genetic profiling links key genes to alcohol-related expectancies. According to recent research from the United States, "molecular genetic research has identified promising markers of alcohol...

Membrane Cofactor Protein identified as adenovirus receptor.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Membrane Cofactor Protein is identified as the adenovirus receptor. "A tandem mass spectrometry-based approach is demonstrated for detecting a receptor for Ad37, one of the causative agents for...

Growth hormone treatment stimulates adiponectin gene expression in adipocytes.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Chronic treatment with growth hormone stimulates adiponectin gene expression in 3T3-L1 adipocytes. "Growth hormone (GH) is an important regulator of adiposity and systemic energy metabolism. Here,...

Carbohydrate response element-binding protein gene expression studied.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Scientists have studied the modulation of carbohydrate response element-binding protein gene expression in 3T3-L1 adipocytes and rat adipose tissue. "Carbohydrate response element-binding protein...

Increased insulin not needed for increases in mouse brain tryptophan.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Increased insulin is not required for beta[subscript]2-adrenoceptor-induced increases in mouse brain tryptophan. "The current study tested the hypothesis that beta[subscript]2-adrenoceptor-mediated...

Combination therapy for liver cancer is linked to interstitial pneumonia.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Combination therapy for liver cancer is linked to interstitial pneumonia. According to recent research published in the Journal of Gastroenterology, "previously we reported combined...

Genes involved in valproic acid teratogenicity identified.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Genes involved in teratogenicity induced by the antiepileptic drug valproic acid (VPA) have been identified. "Embryonic development is a highly coordinated set of processes that depend on...

Slightly increased risk of ischemic stroke found with tamoxifen.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Researchers at Duke University Medical Center have found a slightly elevated risk of ischemic stroke due to a blood clot in the brain in patients treated with tamoxifen, a drug commonly prescribed both...

Study suggests caution against using certain drugs to unclog heart arteries.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Dartmouth Medical School cardiology researchers have discovered a new mechanism for what drives the growth of muscle tissue in the lining of injured heart vessels that can eventually lead to blockage....

Ethanol effects on uncoupling protein-1 mRNA alter thermogenesis set point.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- The effects of ethanol on uncoupling protein-1 mRNA in brown adipose tissue alter the thermogenesis set point. According to recent research from Japan, "Expression of uncoupling protein-1 (UCP1) is...

Study: Anti-dust mite covers effective in reducing allergens.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- A new study provides evidence that people who have allergic asthma and use dust mite-impermeable bed covers have improved peak flow measurements. These findings are featured in the October 2004...

Allergen immunotherapy reviewed.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Researchers review allergen immunotherapy in a recent issue of American Family Physician. According to recent research from the United States, "Allergen immunotherapy (also called allergy vaccine...

NFAT1 protein assists mast cells with interleukin-13 gene transcription.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- NFAT1 protein assists mast cells with interleukin-13 gene transcription. "Th2 and mast cells are participants in the asthmatic response to allergens, and both cell types produce the cytokines...

Patient knowledge of allergy immunotherapy better than expected.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Patient knowledge of allergy immunotherapy was better than expected. "Immunotherapy is an invaluable therapy for allergic asthma, allergic rhinitis, and hymenoptera hypersensitivity. It is, however,...

Biotechcompany scientist presented with award from Alzheimer Association.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Prana Biotechnology Limited (NASDAQ:PRAN)(NASDAQ:ASX:)(NASDAQ:PBT) announced that Dr. Ashley Ian Bush, cofounding scientist and senior scientific consultant to Prana Biotechnology, was named a 2004...

Blood pressure drugs may slow deterioration of Alzheimer.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Certain blood pressure drugs may slow the deterioration of Alzheimer disease, according to a new study. Called angiotensin-converting enzyme inhibitors, or ACE inhibitors, the drugs are used to...

Forecast: Considerable research to be devoted to pathomechanism of Alzheimer.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Management of Alzheimer disease remains a challenge, with nearly 8 million sufferers from this condition in the 7 major world markets and anticipated increases in the future. Considerable research...

NSAID prodrugs show promise for CNS delivery.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- A series of prodrugs of non-steroidal anti-inflammatory drugs (NSAIDs) show promise for CNS delivery of these agents. NSAIDs "have been proposed to prevent or to cure Alzheimer disease," according...

Partnership between government, industry will streamline clinical trials.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- The U.S. National Institute on Aging (NIA) is launching a landmark study to find neuroimaging and other methods for monitoring the progression of Alzheimer disease (AD) aimed at significantly reducing...

Pharma company announces progress with Alzheimer strategy.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Nymox Pharmaceutical Corporation (NASDAQ: NYMX) has made steady progress pursuing a multipronged strategy against Alzheimer disease (AD) that targets the prevention, diagnosis and treatment of AD,...

Pharma company's long-term study of Celebrex expected to continue.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Pfizer Inc. said that three large long-term Celebrex (celecoxib capsules) studies involving more than 6,000 patients have not shown any significant safety issues and are expected to continue to...

CytRx adds three drug candidates with acquisition of Biorex assets.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- CytRx Corp. (CYTR) has acquired all the clinical and pharmaceutical assets and related intellectual property of Hungary-based Biorex Research & Development, RT, (Biorex), a privately held biotechnology...

Phase I trial of Hematide initiated.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Affymax, Inc., announced that it has initiated a placebo controlled, phase I dose-finding clinical trial with its lead product candidate, Hematide, a peptide-based erythropoiesis stimulating agent (ESA)...

JCAHO Sentinel Event Alert issued targeted at preventing anesthesia awareness.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Aspect Medical Systems (ASPM) announced that the Joint Commission on Accreditation of Healthcare Organizations (JCAHO) has issued a new Sentinel Event Alert (issue no. 32) aimed at preventing and...

Microvascular dysfunction encourages the progression of steatohepatitis in mice.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Microvascular dysfunction encourages the progression of steatohepatitis in mice. According to recent research from the United States, "in alcoholic steatohepatitis, hepatic microvascular changes...

Vitamin E can increase carotid artery compliance and baroreflex gain.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- A recent report described the effect of vitamin E on carotid artery elasticity and baroreflex gain in young, healthy adults. According to published research from Hungary, "In [our] study we tested...

Prescriptions for antibiotics to prevent anthrax now uncommon.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Prescriptions for antibiotics that could be taken in advance to prevent against anthrax were uncommon among concerned patients after September 11, 2001 and the 2001 U.S. anthrax attacks, according to a...

Biotech company working to address problem of antibiotic resistance.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- New biotechnology company, RiboNovix, Inc., is addressing the worsening problem of antibiotic-resistant bacteria by developing new anti-infectives that are less susceptible to drug resistance. Over...

Oral fluconazole safe/effective empiric treatment for neutropenic fever.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Oral fluconazole is a safe and effective empiric treatment for persistent neutropenic fever. According to a study from Israel, "Neutropenic patients who continue to be febrile despite adequate...

Antisense inhibitors of TRADD could modulate TNF-related pathologies.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Antisense inhibitors of TRADD could modulate TNF-related pathologies. "Tumor necrosis factor (TNF) receptor 1-associated death domain protein (TRADD) is an adaptor protein known to be involved in...

The antisense mRNA sONE offers endothelial-cell specific gene expression.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- The antisense mRNA sONE offers endothelial-cell specific gene expression. According to a study from Canada, "endothelial nitric-oxide synthase (eNOS) mRNA levels are abnormal in diseases of the...

Antiestrogenic drug combinations may be used for glioblastoma malignancies.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Antiestrogenic drug combinations may be used for glioblastoma malignancies. According to researchers in Turkey, "The antitumor activity of nonsteroidal antiestrogens on C6 and low passage of human...

RANTES haplotypes influence the response to chronic hepatitis C therapy.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- RANTES haplotypes influence the response to chronic hepatitis C therapy. "The response to antiviral therapy for chronic hepatitis C virus (HCV) is complex and is determined by both environmental and...

CD45 plays significant role in nuclear apoptosis by chloride channel regulation.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- CD45 plays a significant role in nuclear apoptosis by chloride channel regulation. According to published research from Canada, "Mitochondrial-perturbating agents such as toxic compounds induce...

Humic acid induces apoptosis in premyelocytic leukemia HL-60 cells.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Humic acid induces apoptosis in promyelocytic leukemia HL-60 cells. According to a study from Taiwan, "It has been shown that humic acid (HA), a phenolic polymer, exhibits pro-oxidant and cytotoxic...

Pharmaceutical company offers its alternative to recalled arthritis medication.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- With the recent recall of the arthritis medication rofecoxib, Boehringer Ingelheim announced that it is supporting patients while they look for new alternatives. The company offered up its own...

Topical medication effective in relieving symptoms of knee osteoarthritis.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Symptoms of primary osteoarthritis of the knee, including pain and stiffness, were significantly improved in patients who used a topical nonsteroidal anti-inflammatory drug (NSAID), according to new...

Glucuronoxylomannan exhibits anti-inflammatory effects in arthritis.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Glucuronoxylomannan exhibits anti-inflammatory effects in collagen-induced arthritis. "This investigation was planned to assess the therapeutic efficacy of glucuronoxylomannan (GXM) in...

Bioassay detects soluble MAdCAM-1 in body fluids.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Researchers have developed a bioassay to detect soluble MAdCAM-1 in body fluids. According to recent research from New Zealand, "Mucosal addressin cell adhesion molecule (MAdCAM-1) is a key player...

Data collection complete for phase III Aridol study.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Final patient recruitment for Pharmaxis' phase III trial of Aridol, its asthma management product, was 654 compared with a target of 600, and 616 patients completed the study. Data collection from...

Suite of asthma control and asthma impact surveys launched.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- QualityMetric Incorporated announced launch of a full suite of asthma control and asthma impact surveys for adults and children that measure health-related quality of life (HRQoL) from the patient...

Drug for rheumatism possible boon to heart patients.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Atherosclerosis, which lies behind heart attacks, stroke and other cardiovascular problems, has a major impact on public health. So does chronic rheumatoid arthritis. These two diseases are completely...

Results presented on antibody-based treatment of atherosclerosis.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- A new report describes the research performed by a research team lead by professor Jan Nilsson at the University Hospital MAS in Malmo in collaboration with BioInvent International AB (BINV) in Lund....

Cholesteryl ester transfer protein induces long-lasting antibodies.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Subcutaneous and mucosal administration of a 26-amino acid cholesteryl ester transfer protein (CETP) epitope carried by heat shock protein 65 kDa in the absence of adjuvants induced long-lasting...

Beta-radiation can create linear lesions that are contiguous and nonthrombogenic.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- A recent report described the use of beta-radiation for the creation of linear lesions in the canine atrium. Creating linear lesions is important for the treatment of arrhythmias such as atrial...

Antinuclear antibody absorption by hepatitis B vaccine warrants evaluation.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Antinuclear antibody absorption by hepatitis B vaccine warrants evaluation. According to published research from France, "the aim of this work is to propose a method to search for a possible...

T cell genes expressed in human and murine autoimmune disease compared.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Scientists have compared differentially expressed genes in T lymphocytes between human autoimmune disease and murine models of autoimmune disease. According to recent research published in the...

Thyroid peroxidase DNA immunization replicates thyroid autoimmunity.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Thyroid peroxidase DNA is superior to protein immunization in replicating human thyroid autoimmunity in HLA-DRB1*0301 (DR3) transgenic mice. "Murine experimental autoimmune thyroiditis (EAT),...

Reassortant influenza vaccines control avian influenza.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Scientists have generated reassortant influenza vaccines by reverse genetics that allows utilization of a Differentiating Infected from Vaccinated Animals (DIVA) strategy for the control of avian...

Biotech firm lauds Nobel winner, announces olfactory-based government contract.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Joseph K. Pagano, chairman of the board of Sentigen Holding Corp. (SGHL), a biotechnology company, extended congratulations to Dr. Richard Axel, Sentigen's long term good friend and consultant, on being...

Oligonucleotide array technology rapidly detects foodborne pathogenic bacteria.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Oligonucleotide array technology rapidly detects foodborne pathogenic bacteria. According to a study from China, "A rapid and accurate method for detection for common pathogenic bacteria in...

Biosynthesis study results of 55 bacterial strains reported.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Researchers in Brazil screened "55 bacterial strains isolated from soil... for efficient poly-3-hydroxybutyrate (P3HB) biosynthesis from xylose. Three strains were also evaluated for the utilization of...

Pharma company completes phase 1 clinical trial for complicated skin infections.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Peninsula Pharmaceuticals, Inc., announced that is has completed a phase 1 clinical trial for PPI-0903, one of its product candidates. Peninsula is investigating PPI-0903 as a potential treatment...

Significance of microbial interactions in biooxidation of pyrite.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Significance of microbial interactions in biooxidation of pyrite. Researchers writing in Biotechnology and Bioengineering explained, "The oxidative dissolution of pyrite (FeS2) by pure and mixed...

Swedish company presents mass screening tests at investment conference.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Swedish blood diagnostics company LifeAssays Inc. presented its mass screening and point-of-care tests on Oct. 21 at the Windhover Information and Medtech Insight's "Investment In Innovation" Event, at...

Triclosan's insertion in cell membrane may account for its antibacterial effect.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Triclosan's insertion into the bacterial cell membrane may account for its antibacterial effect. According to a study from Spain, "Triclosan is a hydrophobic antibacterial agent used in...

Gli proteins up-regulate expression of basonuclin in basal cell carcinoma.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Gli proteins up-regulate the expression of basonuclin in basal cell carcinoma. "Tumorigenesis is frequently accompanied by enhanced rRNA transcription, but the signaling mechanisms responsible for...

Avodart offers improvements in quality of life for men with prostate problems.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Men who suffer from benign prostatic hyperplasia (BPH) experience long-term benefits with the new treatment Avodart, according to a new study. For the first time, the study looked at the effects of...

Peptidomics offers sensitive search for biomarkers.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- The German biotech company BioVisioN opens up new possibilities for peptide biomarker research. Improvements of their proprietary Clinical Peptidomics technologies were presented at this year's...

Lactobacillus spp. biofilm growth promoted by Actinomyces spp., S. mutans.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Lactobacillus species biofilm growth promoted by Actinomyces species and Streptococcus mutans. According to recent research from New Zealand, "The ability of oral bacteria to integrate within a...

BioProcess International Conference & Exhibition unites 1,000 attendees.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- The first-ever BioProcess International Conference & Exhibition in October united more than 1,000 attendees from worldwide biotech and pharmaceutical companies at the Boston Convention & Exhibition...

Polycation-mediated precipitation captures plasmid DNA from alkaline lysate.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Polycation-mediated precipitation captures plasmid DNA from alkaline lysate. "The demand for highly purified plasmids in gene therapy and plasmid-based vaccines requires large-scale production of...

Tetrahydropapaverine seen to inhibit serotonin biosynthesis in murine model.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Tetrahydropapaverine have been seen to inhibit serotonin biosynthesis in a murine mastocytoma model. "The inhibitory effects of tetrahydropapaverine on serotonin biosynthesis in serotonin-producing...

More than 1 million Bioanalyzer chips sold.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Agilent Technologies, Inc., (A) announced that it has sold more than one million LabChip chips - small, analytical devices used with the Agilent 2100 bioanalyzer to perform fast, automated analysis of...

NIH grants awards for the development of human antibody against anthrax.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Medarex (MEDX) announced that it has received two grants from the U.S. National Institute of Allergy and Infectious Diseases (NIAID) to support Medarex's research and development of MDX-1303, a fully...

FDA approves ABILIFY for acute bipolar mania, including manic and mixed episodes.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Bristol-Myers Squibb Co. (BMY) and Otsuka Pharmaceutical Co., Ltd., announced that the U.S. Food and Drug Administration (FDA) has approved ABILIFY (aripiprazole) for the treatment of acute bipolar...

Anticancer effects of DADS characterized.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- The anticancer effects of diallyl disulfide (DADS) have been further characterized. DADS, "one of the major components of garlic (Allium sativum), is well known to have chemopreventative activity...

Molecular assessments can facilitate the management of bladder carcinoma.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Molecular assessments can facilitate the management of bladder carcinoma. According to published research from England, "hypoxia and proliferation are important determinants of radiation...

Interaction of two botulinum subdomains needed to elicit antibodies.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Interaction between the two subdomains of the C-terminal part of the botulinum neurotoxin A is essential for the generation of protective antibodies. According to a study from France, "The botulinum...

Clinical bovine mastitis diagnosed in a Prototheca zopfii outbreak.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Clinical bovine mastitis was diagnosed in a Prototheca zopfii outbreak. According to a study from Brazil, "Biopsy by fine needle aspiration together with microbiological examination and scanning...

Brain metastases patients' radiographic response at 3 months predicts survival.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- For brain metastases patients undergoing whole brain radiation therapy (WBRT), radiographic response in the brain at 3 months is a statistically significant predictor of prolonged survival, according to...

Data on GliaSite Radiation Therapy System presented at ASTRO.
November 5, 2004... 2004 NOV 5 - (NewsRx.com & NewsRx.net) -- Proxima Therapeutics, Inc., announced encouraging results of a postmarket study on the GliaSite Radiation Therapy System as a first-line treatment for single resected brain metastasis. Each year,...