Drug Week articles from November 2001

Drug Week archives from November 2001

Leuprorelin Prevents Menstruation During Treatment Recovery.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in France say that the synthetic hormone leuprorelin, often used to treat prostate cancer, can also prevent menstruation during treatment for...

Plant-Derived Chemicals Prevent Brain Cell Death.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- Two plant-derived chemicals can reduce the damage from a simulated stroke in cultured mouse brain cells, according to a study from the San Francisco Veteran's Administration Medical Center researchers....

Cancer Patients Report Improvements From Healing Tea; Researchers Urge Clinical Trials.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- A study funded by the U.S. National Institutes of Health (NIH) recommended that an herbal tea formula called Flor-Essence should undergo clinical trials due to its widespread use and perceived benefits...

Janus Kinase 3 Inhibitors Can Reduce Graft-Versus-Host Severity.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United States say that drugs that block a key signaling protein may prevent or ameliorate graft-versus-host disease (GvHD) after bone marrow...

BBR 2778 Shows Promise In Preclinical Trials.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- Novuspharma SpA (NOV.MI) announced that Dr. Gonsette from the National Center for Multiple Sclerosis, together with colleagues from the University of Leuven in Belgium, have presented preclinical...

First Oral Drug Proven Effective In Multicenter Trial.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- A first-of-its-kind oral drug has been shown to treat primary pulmonary hypertension (PPH) successfully , according to the results of a multicenter trial led by University of California at San Diego...

Phase II Clinical Trial Of Org 24448 Initiated.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- Cortex Pharmaceuticals, Inc. (COR) announced that it had been notified of Organon's intent to continue development of the Ampakine Org 24448 in a Phase II trial as a potential treatment for...

AIDS-Related CMV Retinitis Drug Receives Approval in Europe.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- Roche announced that Valcyte received regulatory approval for the treatment of AIDS-related cytomegalovirus (CMV) retinitis in the Netherlands. This decision by the Dutch Medicines Evaluation Board...

ViroLogic Enters Agreement With Triangle Pharmaceuticals To Evaluate New HIV Drugs.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- ViroLogic Inc. has signed an agreement with Triangle Pharmaceuticals Inc. to assist in clinical evaluation of new anti-HIV agents in development at Triangle Pharmaceuticals. Triangle Pharmaceuticals...

Hybrigen And Bionomics Announce Drug Target Discovery Alliance.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- Hybrigen Inc. and Bionomics Ltd. (BNO) have signed a letter of intent to negotiate the terms of a collaboration to discover drug targets in breast cancer. The drug target discovery program will be...

Oral Renin Inhibitor Aliskiren Moves Into Additional Development Activities.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- Speedel Pharma AG, a member of the Speedel Group, a cardiovascular and metabolic drug development company based in Basel, Switzerland, will continue to develop Aliskiren (SPP 100) through an additional...

GSK And Tanabe To Develop Preclinical Products.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- Tanabe Seiyaku Co. Ltd. and GlaxoSmithKline PLC (GSK) have signed a letter of intent to enter into a broad-ranging global collaboration on the research, development, and commercialization of a series...

Merck KGaA Partners With ImClone, Bristol-Myers Squibb To Develop C225.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- Merck KGaA has clarified that it acquired the worldwide rights to develop and commercialize the cancer drug C225 outside the U.S. and Canada in December 1998 from ImClone Systems Inc. of New York City....

Genotyping Kit Is First DNA Sequence-Based Test For HIV Drug Resistance Testing.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- Visible Genetics, Inc. (VGI) received clearance September 26, 2001, from the U.S. Food and Drug Administration (FDA) to market its Trugene HIV-1 Genotyping Kit and OpenGene DNA Sequencing System for...

Carrington Subsidiary Will Advance Controlled-Release Technology.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- Carrington Laboratories Inc. is forming a subsidiary to develop its patented drug delivery technology. This technology, first announced at a scientific conference in June 2001, employs a natural...

High-Throughput Screening System Has Expanded Capabilities.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- Molecular Devices Corporation announced the launch of FLIPR 3, a more sensitive, higher throughput version of the FLIPR Fluorescent Imaging Plate Reader system used primarily in high-throughput...

Morphotek Announces Research Agreement With Wyeth-Ayerst Laboratories.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- Morphotek, Inc. announced September 27, 2001, that it has signed a collaborative research agreement with Wyeth-Ayerst Laboratories, the pharmaceutical division of American Home Products Corporation....

Odyssey Pharmaceuticals Awarded Second Patent For Target Validation and Drug Discovery Platform.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- Odyssey Pharmaceuticals, Inc. announced September 28, 2001, that the United States Patent and Trademark Office has issued U.S. Patent No. 6,294,330 entitled "Protein fragment complementation assays for...

Direct-To-Consumer Advertising Ambiguous, Study Concludes.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- American consumers are given incomplete prescription-drug information in advertising campaigns directed to them, report Dartmouth Medical School/Veterans Affairs physicians. Pharmaceutical...

Quality/Safety Standards Of Traditional Chinese Medicines Investigated.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- The Medicines Control Agency (MCA) begin consulting September 27, 2001, on proposals to extend the list of potent or toxic ingredients which are not permitted in unlicensed herbal medicines. It...

Phase III Drug Candidate Receives Orphan Drug Designation.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration has granted Enteron Pharmaceuticals Inc., the majority-owned subsidiary of Corporate Technology Development Inc., an orphan drug designation for use of orBec to...

Class Action Lawsuit Against Serologicals Corp. Dismissed.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- The United States District Court for the Northern District of Georgia, Atlanta Division has ordered the dismissal of the class action lawsuit alleging securities fraud against Serologicals Corp....

Court Decision Clears Way For Generic Tiazac.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- A Florida judge has ruled against Biovail Corp. in a patent case involving the heart drug Tiazac. Biovail filed a new patent on Tiazac last spring, just as the old patent was about to expire. The...

POZEN to Submit MT 100 Carcinogenicity Study Results To FDA In Early 2002.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- POZEN Inc. (POZN), a pharmaceutical development company with a portfolio of product candidates for the treatment of migraine, will submit the results of the mouse carcinogenicity study in the first...

Genasense Gets FDA Fast Track Designation.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- Genta Inc. (GNTA) has received notice from the U.S. Food and Drug Administration that Genasense, its lead anticancer compound, has been granted fast track designation for multiple myeloma. Genasense...

Neuroimmunophilin Ligand Program Returned To Guilford Pharmaceuticals.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- Guilford Pharmaceuticals, Inc. (GLFD), announced that Amgen (AMGN) has elected to terminate its agreement with Guilford and return all rights to the neuroimmunophilin ligand technology it licensed from...

Encouraging ADL 8-2698 Study Data Published.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- Adolor Corporation announced September 27, 2001, that its lead drug candidate, ADL 8-2698, shows promise as a preventative against opioid bowel dysfunction. Specifically, a team of researchers, led...

AstraZeneca Signs Multiyear Global Agreement With Tripos.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- Tripos Inc. (TRPS) has signed a multiyear, multimillion dollar agreement with AstraZeneca (AZN) to provide the SYBYL suite of in silico drug discovery technologies to the pharmaceutical company's life...

Quality Control System Cuts Time for Assay Development.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- Biacore International AB (BCOR) has launched its Biacore C system for rapid concentration analysis in drug development, manufacturing quality control (QC), and in-process control applications. Biacore...

FDA Offers Further Elaboration On Clinical Hold Of Cancer Vaccines.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- AVAX Technologies Inc. (AVXT) has received additional correspondence from the FDA related to the agency's clinical hold for the clinical trials of M-Vax and O-Vax, AVAX's autologous cell cancer...

Sparfloxacin Affects Mycobacterial Cell Envelope.
November 2, 2001... 2001 OCT 26 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The antibiotic sparfloxacin has a more diverse range of action on mycobacteria (including tuberculosis) than previously realized, according to researchers in...

Oral Delivery Of Insulin Deemed Safe, Nontoxic In Animal Studies.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Generex Biotechnology Corporation announced positive results from a long-term safety and toxicology study of Oralin, an oral insulin spray formulation, which was performed in dogs. The study showed...

Intermittent Streptomycin Doses May Increase Efficacy.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Colorado say that intermittent doses of the antibiotic streptomycin can maximize its effectiveness in treating tuberculosis. C.A. Peloquin...

Abacavir Pharmacokinetics Unaffected By Renal Impairment.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Patients suffering from both HIV infection and kidney dysfunction can be treated with unmodified abacavir regimens, according to researchers in France. ...

Infliximab Can Increase Tuberculosis Risk.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The monoclonal antibody infliximab may put patients at risk for tuberculosis infection, researchers in the United States warn. "Infliximab is a humanized...

Novel Anticancer Drugs Selectively Activate Apoptosis.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Myriad Genetics, Inc. has discovered a novel drug target for the treatment of a broad range of cancers and has initiated lead optimization with a series of compounds that selectively kill cancer cells....

Acetaminophen Not Linked To Liver Injury In Alcoholics.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Results of a recent study show repeated use of the maximum recommended daily dose of acetaminophen, the medicine in Tylenol, is not associated with evidence of liver (hepatic) injury - even in high-risk...

Unique Sperm Protein A Possible Contraceptive Target.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- An ion channel protein that plays a central role in sperm motility could be an enticing target for a new type of contraceptive that could be taken by either men or women to block fertilization. The...

Scientists Prove That Protein Plays Role In Tumor Blood Supply.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- A genetic analysis of a protein believed to affect the formation of blood vessels has proved that Thrombospondin-1 does indeed regulate a tumor's ability to form the independent blood supply that...

FDA Awards $1.4 Million Grant For Drug Candidate.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Neurochem, Inc. (NRM) announced that it received a $1.4 million grant from the U.S. Food and Drug Administration (FDA) for a Phase II/III study of Fibrillex, which is currently underway. The...

Voriconazole Effective Treatment Of Fungal Infections.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Pfizer, Inc., said that an Advisory Committee to the U.S. Food and Drug Administration (FDA) unanimously recommended approval of both oral and intravenous formulations of voriconazole for the treatment...

Evidence Of Cancer Risks From Ritalin Use.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- The following statement is from Samuel S. Epstein, MD, chairman of the Cancer Prevention Coalition. Based on an industry-funded multi-university trial on 282 pre-teen children treated with Ritalin...

Treatment Now Widely Available After Four-Year Limited Access.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Questcor Pharmaceuticals, Inc. announced that it began shipping HP Acthar Gel (repository corticotropin injection) to wholesalers after a four-year period during which limited supplies were available....

SkyePharma Gets FDA Approvable Letter For UroXatral.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- SkyePharma PLC and Sanofi-Synthelabo have received an "approvable letter" from the U.S. Food and Drug Administration (FDA) for UroXatral (once-daily formulation of alfuzosin) for the symptomatic...

Genta's Decoy Program Suppresses Key Cancer Genes In Breast and Ovarian Cancer.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Genta Inc. has announced the publication of two scientific papers that show an important pipeline drug downregulated key cancer genes and exerted potent preclinical antitumor activity in breast and...

FDA Fast Tracks Antigenics' Oncophage For Kidney Cancer.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration has designated Oncophage, a cancer vaccine candidate developed by Antigenics, Inc. (AGEN), a Fast Track Product for the treatment of renal cell carcinoma. In...

Novel Muscarinic Mechanism Has Potential Therapeutic Application.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- ACADIA Pharmaceuticals announced the discovery of a new approach to the treatment of chronic pain, using small molecules that selectively activate a specific subtype of the muscarinic receptor. ...

Velos Launches Free Internet Clinical Research Service.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Velos, a leading health care software and Internet services vendor, has launched a transformational investigator-centered, Internet-based clinical trials management service called Velos eResearch....

Tranzyme To Codevelop Cell Lines For Cystic Fibrosis Drug Discovery.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Tranzyme Inc. and Cystic Fibrosis Foundation Therapeutics Inc. (CFFTI), a nonprofit affiliate of the Cystic Fibrosis Foundation, have entered a partnership to develop novel cell lines to be used for...

Helicon Therapeutics To Test New Treatments For Memory Enhancement.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- The Institute for the Study of Aging (ISOA) is providing grant funding of $238,780 to Helicon Therapeutics to study novel memory enhancing drugs in a number of animal models of memory. The drugs work...

Investigational New Drug Application Filed For AIT-034.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- NeoTherapeutics, Inc. has announced that it has filed an investigational new drug application (IND) with the U.S. Food and Drug Administration (FDA) to begin human clinical studies of AIT-034. ...

OC-1016 Stimulates Bone and Tissue Regeneration.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- OraPharma, Inc. announced that Sven Glindemann, DMD, of Harvard School of Dental Medicine, Department of Periodontology, presented data from a preclinical study of OraPharma's compound OC-1016 for bone...

Clinical Trials Of Topical VEP/PC Biotechnology Commencing In Virginia.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Phlo Corporation (Phlo) has announced that it plans to conduct clinical trials at the Medical College of Virginia, Virginia Commonwealth University, in Richmond, Virginia, related to the use of its...

Phylos, Lawrence Livermore Lab To Develop High Throughput Methods.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Phylos, Inc. has partnered with Lawrence Livermore National Laboratory to develop high throughput methods for protein production to create research reagents and microarrays that may be used to design...

Intranasal Human Growth Hormone Phase I Clinical Trial Initiated.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Nastech Pharmaceutical Company, Inc. announced that it has commenced a Phase I clinical trial in the United States to evaluate the nasal administration of somatropin (recombinant human growth hormone,...

Avax Expects Clearance To Continue With Its Autologous Cell Vaccines.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Avax Technologies, Inc. has submitted its response to the U.S. Food and Drug Administration's (FDA) request for additional information related to the clinical hold of Avax's clinical trials of M-Vax and...

Entomed Gains Access To Insects From Shanghai Institute.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Entomed, which develops medicines derived from the biology of insects, has announced a new collaboration with the Shanghai Institute of Entomology from the Institutes for Biological Sciences of the...

Immune-Regulating Hormone Enters Clinical Trials.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Hollis-Eden Pharmaceuticals, Inc. announced that it has received approval to initiate a Phase II clinical trial in hepatitis B (HBV) infected patients with its investigational drug, HE2000, at Mt....

Oxagen Licenses Gene Polymorphism Patients From Isis Innovation.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Oxagen Limited in Abingdon, U.K., has acquired exclusive rights to a series of patents from Isis Innovation, the technology transfer arm of Oxford University. The patents cover gene polymorphisms...

Positive Phase II Clinical Results For Novel Painkiller Announced.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Pain Therapeutics, Inc. announced positive results from preliminary analysis of a large Phase II clinical trial with PTI-555, an investigational painkiller aimed at the U.S. market for morphine and...

Primary Endpoint Reached In Pivotal Phase III Trial Of Daptomycin.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Cubist Pharmaceuticals, Inc. announced preliminary results from Study 9801, the second of two pivotal Phase III clinical trials assessing the safety and efficacy of its investigational drug Cidecin...

ViroLogic Broadens Agreement With Roche and Trimeris For Technology Use.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- ViroLogic, Inc. has signed an expanded agreement with Hoffmann-La Roche, Inc. and Trimeris, Inc. to use ViroLogic's proprietary HIV resistance testing technology in the development of T-20 and T-1249,...

Possible Permanent Hearing Loss From Extensive Use Of Painkillers.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- In a retrospective observation conducted at the House Ear Clinic (HEC) in Los Angeles, California, physicians have found a possible correlation between permanent hearing loss and a commonly prescribed...

Antex To Continue DOD Grant Work On Gastrointestinal Vaccine.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Antex Biologics, Inc. has announced it completed work funded by a U.S. Army Small Business Innovation Research (SBIR) grant on the development of an oral microbead vaccine to protect U.S. troops against...

Estrogen Protection May Explain Differences In Response Between Sexes.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Estrogen may play a role in protecting against endotoxic shock associated with Vibrio vulnificus infection, a finding that may help explain the vast difference between the infection in men and women....

Alpharma Assumes Management Of Faulding's Generic Pharmaceutical Businesses.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Alpharma Inc., a specialty pharmaceutical company, has assumed operating management responsibility of the F.H. Faulding's generic oral solid dose businesses. Alpharma had previously announced its...

Bayer Long-Term Ratings Cut to AA(minus) After Drug Withdrawal and Acquisition Talks.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Standard & Poor's lowered its long-term ratings on the German pharmaceuticals and chemicals group Bayer AG (Bayer) and related entities to AA(minus) from AA. All ratings remain on CreditWatch, where...

Genetic Predisposition May Explain Drug Reactions.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- GlaxoSmithKline (GSK) and First Genetic Trust announced a research collaboration to study the genetic variations that influence why some patients experience certain adverse reactions when taking a...

Viragen Reports On Avian Transgenic Project.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Viragen, Inc. and Roslin Institute (Scotland) jointly reported on the progress of the Avian Transgenic Project. Using the same antibody construct previously expressed in chicken cell lines, Viragen...

360-Degree Display Aids Firm In Defining Protein Structures.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Actuality Systems, Inc. has announced that the first beta customer for its spherical 3-D display is Structural GenomiX, Inc., (SGX) in San Diego, California. SGX transforms genomic information into...

Cyclacel's CDK Inhibitor Candidate Meets Safety Objectives.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Cyclacel Limited, a United Kingdom-based cancer therapeutics company, has announced that CYC202, its lead CDK-inhibitor drug candidate, has completed Phase Ia evaluation in humans and is entering...

Hybrigenics Expands Alliance With Institut Pasteur.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Hybrigenics and Institut Pasteur have announced that they have signed an exclusive collaboration in the field of functional proteomics applied to infectious diseases. The new agreement provides an...

Amarillo Biosciences Receives Grant To Develop H. pylori Vaccine.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Amarillo Biosciences, Inc. has received a Small Business Innovative Research (SBIR) grant from the U.S. National Institutes of Health (NIH) for $96,248 to be used to develop a vaccine to combat...

IntegriDerm Awarded NIH Grant To Study Diagnostic Biomarkers For GI Diseases.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- IntegriDerm Inc. has been awarded a U.S. National Institutes of Health (NIH) Small Business Innovation Research (SBIR) Phase I grant for $147,650 to study the gastrointestinal tract. IntegriDerm is a...

PhRMA Survey Finds 785 Drugs in Development for Diseases Affecting Older Americans.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- New medicines in the pipeline for Alzheimer disease, osteoporosis, arthritis, and Parkinson disease are among the many promising treatments in development for these and other diseases of aging,...

Ancient Chinese Remedy Studied For Gastric Upsets.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- An ancient Chinese medicine extracted from pine trees may be effective against ulcers, heartburn, reflux esophagitis and other digestive disorders common in the Western world, say scientists. Dr....

Phase II Trial Initiated By Ribozyme Pharmaceuticals.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Ribozyme Pharmaceuticals (RPI) announced the beginning of a multicenter Phase II clinical trial utilizing Heptazyme for the treatment of patients with chronic hepatitis C. Heptazyme, developed by...

Study Quantifies Risk To Patients Participating In Clinical Trials.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- A recent CenterWatch study finds that the incidence of deaths attributed to investigational treatments, during both government and industry-sponsored clinical trials, is rare. The study also finds that...

Celgene Receives Orphan Drug Designation For Revimid.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Celgene Corp.'s Revimid, the company's lead immunomodulatory drug (IMiD), has been granted orphan drug designation by the U.S. Food and Drug Administration (FDA) for multiple myeloma. Orphan drug...

Enrollment Completed For Phase II Trial Of LDP-341.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Millennium Pharmaceuticals, Inc. announced that it has completed enrollment of a Phase II clinical trial of LDP-341 (formerly PS-341) in patients with multiple myeloma. The accrual was completed ahead...

Commonly Prescribed Sedative May Cause Delirium Symptoms In Elderly.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- The frequently prescribed antihistamine and sedative medication diphenhydramine is associated with a 70% increased risk of changes in mental status and evidence of delirium symptoms in older,...

Experiments Offer Major Clue To Repairing Diseased Nerves.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Using specially designed and bred laboratory mice, scientists at the University of North Carolina at Chapel Hill have discovered that a well-known protein in the body called tumor necrosis...

Modafinil Significantly Improves Wakefulness In Patients.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Cephalon, Inc. has announced results from a 327-patient, multicenter clinical study that indicate Provigil (modafinil) Tablets [C-IV] increased daytime wakefulness in patients suffering from excessive...

Nasal Calcitonin Reduces Bone Loss By Over 40%.
November 9, 2001... 2001 NOV 9 - (NewsRx.com & NewsRx.net) -- Unigene Laboratories, Inc. (UGNE) reported that the analysis of the data from the pivotal clinical trials for its proprietary nasal calcitonin spray showed a rapid and persistent reduction in bone loss...