Drug Week articles from June 2002

Drug Week archives from June 2002

Cyclosporin A may be unsuitable for use during organ transplants.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The immunosuppressant cyclosporin A may not be a suitable treatment for HIV[superscript]+ patients undergoing solid organ transplantation, researchers in the...

Lamivudine can heighten transplacental zidovudine toxicity.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The antiretroviral agent lamivudine may increase the toxicity of zidovudine when the two drugs are used to prevent peripartum transmission of HIV, researchers...

Tenofovir cytotoxicity lower than that of similar agents.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The nucleoside reverse transcriptase inhibitor (NRTI) tenofovir is less toxic to cells than similar agents, researchers in the United States report. ...

Research: Common acne antibiotic minocycline delays progression of ALS.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- Project A.L.S.-funded researchers at Brigham and Women's Hospital (BWH) have identified the process in which the antibiotic minocycline, commonly prescribed for acne, inhibits the progression of cell...

Commonly prescribed antibiotic ineffective.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- A U.S. study in the May 11, 2002, issue of the Lancet concludes that the antibiotic azithromycin is ineffective for treating bronchitis, even though it is often prescribed by physicians for this...

Researchers seek new hope in old treatment.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- Theophylline, an asthma medication prescribed since the 1970s, is now being studied for new potential merits. The Effectiveness of Low Dose Theophylline as Add-On Therapy in the Treatment of Asthma...

New radioimmunotherapy drug proves highly effective.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- A Mayo Clinic study indicates the first of a new class of drugs involving radioimmunotherapy benefited a significant number of patients with low-grade B cell non-Hodgkin lymphoma who have exhausted...

Protease inhibitors enhance life expectancies but can cause adverse effects.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- Breakthroughs in protease inhibitors (PIs), drug therapies designed to combat HIV, have enhanced the life expectancies of those infected with the virus. However, there is increasing evidence that PI...

IND application submitted for new nitroglycerin lingual spray.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- Flemington Pharmaceutical Corporation announced that that it has filed an investigational new drug application (IND) with the Division of Cardiorenal Drug Products of the U.S. Food and Drug...

Botox approved by FDA for cosmetic use.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- On April 15, the U.S. Food and Drug Administration officially approved the use of Botox for use as a cosmetic. This unparalleled turn in the dermatology world will change the face of an entire...

Collaboration to involve high throughput screening of Japanese compounds.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- CombinatoRx, a privately held biopharmaceutical company, announced a 3-year research collaboration with Sosei Co., Ltd., a leading Tokyo-based biopharmaceutical company, to discover novel combination...

Company provides update of progress.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- Human Genome Sciences, Inc., (HGSI) recently told financial analysts in New York that the company expects to file four investigational new drug (IND) applications in 2002, seeking clearance from the...

NDA submitted for new antifungal product.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- Fujisawa Healthcare, Inc., (Fujisawa) announced that a new drug application (NDA) has been submitted to the U.S. Food and Drug Administration (FDA) for their antifungal product micafungin. "The...

Zofran may reduce vomiting associated with acute gastroenteritis in children.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- The results of two recently published studies suggest that the use of the antiemetic Zofran (ondansetron hydrochloride) may reduce vomiting episodes in children treated in the emergency department for...

Studies: CellCept benefits patients reinfected with after liver transplant.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- The immunosuppressive drug CellCept (mycophenolate mofetil) positively altered the course of hepatitis C reinfection after liver transplantations in three investigational studies reported at the...

CEL-SCI announces that its derG peptide protects against malaria in mice.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- CEL-SCI Corporation (CVM) and the Naval Medical Research Center (NMRC) announced the presentation of detailed protection results against malaria challenge obtained with CEL-SCI's newly discovered...

Alcon releases results for anecortave acetate therapy.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- Alcon Research, Ltd., reported preliminary results from its phase II clinical trials demonstrating that anecortave acetate, one of its key drugs under development, preserves or improves vision in...

Study shows that ePocrates helps reduce drug errors.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- In the first published study evaluating the clinical impact of handheld drug reference guides, researchers at Brigham and Women's Hospital, a teaching affiliate of Harvard Medical School, demonstrated...

GD0039 phase II clinical results are positive.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- GlycoDesign, Inc., a leading Canadian biopharmaceutical company, announced the release of important data from the first phase II clinical trial for GD0039, the company's lead anticancer drug. The...

First patient enrolled in pivotal phase III study of Oncophage.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- Antigenics, Inc., (AGEN) announced that investigators have enrolled the first patient in a pivotal phase III trial of its personalized cancer vaccine Oncophage (HSPPC-96) for the treatment of metastatic...

INCOMIN data showing superior efficacy of Betaferon/Betaseron vs. Avonex.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- Schering AG announced that the final 2-year results from INCOMIN (Independent Comparison of Interferon) study were published on April 27 in the peer-reviewed journal, The Lancet. The results show that...

IND approved for buccal morphine.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- Generex Biotechnology Corporation (GNBT), a leader in the area of buccal drug delivery, announced that the U.S. Food and Drug Administration (FDA) has approved an investigational new drug (IND)...

Proof-of-concept study for buccal fentanyl citrate completed.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- Generex Biotechnology Corporation (GNBT), a leader in the area of buccal drug delivery, announced that it successfully completed a proof of concept clinical study of fentanyl citrate delivery using its...

Human Genome Sciences initiates clinical development of a novel anticancer drug.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- Human Genome Sciences, Inc., (HGSI) announced that it has received clearance from the U.S. Food and Drug Administration (FDA) of its investigational new drug (IND) application to begin trials of a novel...

Immunosuppressive therapy with Prograf reduces rejection risk in pediatric liver transplant patients.
June 7, 2002... 2002 JUN 7 - (NewsRx.com & NewsRx.net) -- Pediatric patients receiving liver transplants are less likely to suffer acute rejection if they receive immunosuppressive therapy based on Prograf (tacrolimus), as opposed to ciclosporin microemulsion....

Ramoplanin beats antibiotic resistance by fighting the battle on its own terms.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- In a new report in the Proceedings of the National Academy of Sciences USA, researchers at the University of Pennsylvania School of Medicine describe how one antibiotic currently under phase III...

Cancer drug proves effective therapy.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- Researchers at the University of Illinois at Chicago College of Medicine have demonstrated that a drug long used to treat cancer is also effective in combating sickle cell disease. The drug,...

Venlafaxine significantly effective for children and teens.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- Venlafaxine HCl is a significantly effective and well-tolerated treatment for children and adolescents who have generalized anxiety disorder (GAD), according to clinical trial data presented at the...

Viagra significantly effective, well-tolerated for men taking multiple blood pressure treatments.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- More than 80% of men taking two or more drugs for their high blood pressure reported improvement in their erections and their ability to have sexual intercourse after taking Viagra (sildenafil citrate)...

Patients with advanced B-CLL double life expectancy in clinical trial.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- Life expectancy for patients with B cell chronic lymphocytic leukemia (B-CLL) doubled from eight to 16 months in a worldwide clinical trial of alemtuzumab (CampathR), according to lead researcher Dr....

Higher filgrastim doses increase stem cell yield, toxicity risk.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - High doses of granulocyte colony-stimulating factor (G-CSF) provide more efficient mobilization of stem cells for transplantation, but can increase patient...

Research suggests diabetes drug being prescribed even when contraindicated.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- Some doctors prescribe metformin, the most widely used type 2 diabetes treatment drug, for patients also suffering from congestive heart failure or kidney dysfunction or both despite clear warnings on...

Simplified antiretroviral regimen safe, effective.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Anti-HIV maintenence therapy consisting solely of reverse transcriptase inhibitors provides benefits comparable with those of conventional regimens, with...

Positive outcome of FDA advisory committee's review of Acamprosate data revealed.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- Forest Laboratories (FRX) and Merck KGaA announced that an advisory committee to the U.S. Food and Drug Administration (FDA) concluded that clinical trial data for acamprosate demonstrates efficacy in...

Dynavax initiates first human trial of ISS for Asthma.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- Dynavax Technologies, a privately held biopharmaceutical company, announced it has initiated a phase I clinical study to evaluate the safety and tolerability of its inhaled ISS (immunostimulatory DNA...

Endovasc presents canine results of intramyocardial injection of Angiogenix.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- Endovasc, Ltd., Inc., (ENDV; ED7) presented new data in a poster entitled "Nicotine Delivered via Intramyocardial Injections Proved Safe in Canines" at the 11th International Congress on Cardiovascular...

Clinical data on Thalomid in combination with Irinotecan presented.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- Celgene Corp. (CELG) reported clinical data from a phase II trial of Thalomid (thalidomide) and Camptosar (irinotecan) in metastatic colorectal cancer at the 38th annual meeting of the American Society...

Company reacquires rights to ramoplanin for topical use from IntraBiotics.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- Biosearch Italia SpA (BIO.MI) has reacquired North American development and commercialization rights to Ramoplanin for topical applications from IntraBiotics Pharmaceuticals, Inc (IBPI). Following...

Enrollment completed in phase II/III clinical trial of Neurodex.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- Avanir Pharmaceuticals (AVN) announced that enrollment has been completed in a Phase II/III clinical trial of Neurodex in the treatment of emotional lability. The objectives of the trial are to...

Positive 12-month phase II results for CAT-152 reported.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- Cambridge Antibody Technology announced the 12-month follow-up results from a phase II clinical trial using CAT-152 (lerdelimumab; human anti-TGFBeta2 monoclonal antibody) in patients undergoing...

Clinical trial results of StreptAvax presented at international vaccine conference.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- ID Biomedical announced that Shelly McNeil of Dalhousie University in Halifax presented phase I clinical trial results for StreptAvax at the Fifth Annual Conference on Vaccine Research. McNeil's...

Genetronics launches phase III trial of electroporation therapy.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- Genetronics Biomedical Corporation, San Diego, (GEB) Toronto announced that the company is launching a phase III clinical trial evaluating its MedPulser system in combination with the generic...

Biovail reports graded-release diltiazem helps control blood pressure surges.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- Biovail Corp.'s (BVF) new graded-release formulation of diltiazem hydrochloride given at 10 p.m. provided the most significant reductions in blood pressure in the hours between 6 a.m. and noon, a time...

Data shows new pain relief treatment effectively reduces pain, narcotic use, costs.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- Results from a new study of women who underwent an abdominal hysterectomy showed that 43% of patients using the narcotic-free ON-Q Post-operative Pain Relief System did not need the usual...

Data presented on cetuximab combined with docetaxel.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- ImClone Systems Inc. (IMCL) and Bristol-Myers Squibb (BMY) announced data from a study of the investigational monoclonal antibody Erbitux (cetuximab) in combination with docetaxel. Data showed the...

New experimental pill found to improve symptoms and quality of life.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- An experimental pill has been found to improve symptoms and quality of life in patients with non-small-cell lung cancer, according to research findings presented by Ronald B. Natale, MD, acting medical...

Decision Resources publishes new report on obesity.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- Decision Resources announced the availability of a new report on obesity. The report includes information on therapies in development such as Axokine from Regeneron, which may be the first obesity...

GlaxoSmithKline alerts patients, pharmacists, physicians to watch for incorrectly labeled Combivir.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- GlaxoSmithKline (GSK) announced that the company has received four reports of suspect bottles containing 60 tablets of Combivir (lamivudine plus zidovudine) that actually contained another medicine,...

Knockout blood protein drug signals possible new treatment for Alzheimer and diabetes.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- Scientists at the University College London (UCL) have developed a drug to treat a serious medical condition linked to Alzheimer disease and type 2 diabetes. The research, supported by the Medical...

Long-term survival data in phase II trial of GVAX vaccine reported at conference.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- Cell Genesys, Inc. (CEGE) has reported encouraging long-term survival data from a phase II multicenter clinical trial of GVAX prostate cancer vaccine which demonstrates a dose-dependent trend toward...

Molecularly targeted drug slows tumor growth in patients.
June 14, 2002... 2002 JUN 14 - (NewsRx.com & NewsRx.net) -- Researchers from the National Cancer Institute (NCI) have reported that the molecularly targeted drug bevacizumab slowed tumor growth in patients with metastatic renal cell carcinoma, the most common...

Tetra-arsenic tetra-sulfide safe, effective.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Tetra-arsenic tetra-sulfide (As[subscript]4S[subscript]4) shows promise for the treatment of patients suffering from acute promyelocytic leukemia (APL),...

Prevalence of diabetes increased for patients on atypical antipsychotics.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - The prevalence of diabetes was seen by U.S. researchers as significantly higher for schizophrenic patients receiving atypical neuroleptics than for...

Oral glycoprotein IIb/IIIa associated with 31% increase in mortality.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- Despite the success of intravenous glycoprotein IIb/IIIa antagonists to prevent recurrent cardiac events, several clinical trials have revealed that oral formulations have thus far failed to show the...

New antibiotics may treat antimicrobial resistance.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- Researchers at the University of Pennsylvania School of Medicine describe how one antibiotic currently under phase III clinical testing, ramoplanin, works on the molecular level to disrupt the ability...

Methotrexate interferes with KS virus gene transcription.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The anti-inflammatory drug methotrexate (MTX) disrupts gene activity by the virus responsible for Kaposi's sarcoma, researchers say. "Kaposi's...

Drug prescribing by nurses in the U.K. - Editor of Lancet urges caution.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- The contentious issue of drug prescribing by nurses is assessed by Richard Horton, editor of the Lancet, in a commentary in the June 1, 2002, issue of the journal. He concludes that U.K. government...

Stem cell transplantation feasible after arsenic trioxide therapy.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Hematopoietic stem cell transplantation is feasible for acute promyelocytic leukemia patients treated with arsenic trioxide, researchers in Italy report. ...

Interleukin-12 blocks stem cell eosinophil differentiation.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United States have shed new light on the mechanisms by which the cytokine interleukin (IL)-12 relieves the symptoms of asthma. ...

Neurocrine Biosciences announces positive phase I results with GnRH receptor antagonist.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- Neurocrine Biosciences, Inc., (NBIX) announced the completion of the first phase I clinical trial with its proprietary, orally active small molecule gonadotropin-releasing hormone (GnRH) receptor...

Cambridge Antibody reports interim results on several trials.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- Cambridge Antibody Technology (CAT) has released interim results of several monoclonal antibody studies underway. Professor Peter Garland, CAT's chairman, said, "In the first 6 months of the year...

Study: Few new drugs in last decade were improvement.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- Only 15% of new drugs approved in the U.S. during the last decade were novel chemicals that the U.S. Food and Drug Administration (FDA) deemed a significant improvement over older drugs, a study says...

Adolor Corporation reports first quarter 2002 financial results.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- Adolor Corporation (ADLR), a biopharmaceutical company specializing in pain management, reported financial results for the quarter ended March 31, 2002. For the first quarter of 2002, the company...

Amarin Corporation reports first-quarter sales and earnings.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- Amarin Corporation plc (AMRN) reported that total revenues grew 165% to $17.6 million for the first quarter ended March 31, 2002. For the quarter, net income rose 34 percent to $1.6 million and...

Avanir reports results for second quarter of fiscal 2002.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- Avanir Pharmaceuticals reported financial results for the second fiscal quarter ended March 31, 2002, and provided a progress report on its drug development strategy, which is focused on large market...

GI cancer patients still responding to Gleevec after 1 year follow-up.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- New data demonstrate that more than 60% of patients with an inoperable and life-threatening form of gastrointestinal cancer (gastrointestinal stromal tumors, or GISTs) are continuing to respond to the...

Apotex announces FDA approval of generic cyclosporine capsules.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- Apotex Corp. announced the approval by the U.S. Food and Drug Administration (FDA) of the company's abbreviated new drug application (ANDA) for cyclosporine capsules, USP in both 25 mg and 100 mg...

Emisphere reports results from phase III oral heparin trial.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- Emisphere Technologies, Inc., (EMIS), announced initial results from its phase III study with an oral heparin formulation for the prevention of deep vein thrombosis (DVT, or blood clots) in total hip...

Study: 9 in 10 hepatitis C patients with cirrhosis are virus free on PEGASYS with ribavirin.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- Early results from an ongoing study by the Swiss Association for the Study of the Liver show that PEGASYS [peginterferon alfa-2a] used in combination with a standard dose of ribavirin (1000-1200 mg)...

'Real world' study indicates effective control of hypertension possible in three patient subgroups.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- In one of the largest community-based trials of its kind, researchers found that high blood pressure can be effectively controlled in African Americans, people with diabetes and the elderly, according...

Campath study shows increased life expectancy.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- Life expectancy for heavily pretreated B-cell chronic lymphocytic leukemia (B-CLL) patients, who were subsequently treated with Campath/MabCampath (alemtuzumab), was shown to double, from 8 to 16...

Brain cancer drug candidate G207 receives orphan drug status.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- The German-American biopharmaceutical company MediGene (MDG) announced that the Office of Orphan Products Development (OOPD) of the U.S. Food and Drug Administration (FDA) has granted orphan drug...

Avonex (interferon (beta)-1a) gains Medicare coverage.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- Biogen, Inc., (BGEN) announced that Medicare will provide coverage for multiple sclerosis patients treated with Avonex as part of physician services. The action by the Center for Medicare and Medicaid...

Lilly, patients hope drug for asbestos-related cancer gains OK.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- Eli Lilly and Co. is working with U.S. regulators to speed up review of a drug to treat a rare cancer linked to asbestos exposure. If approved, the drug, known as Alimta, would become the first...

Phase II trial of squalamine shows encouraging results.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- Genaera Corporation (GENR) announced the presentation of encouraging results for its antiangiogenic drug, squalamine, in its phase II recurrent advanced ovarian cancer clinical trial, at the meeting of...

Atrasentan (ABT-627) offers hope to patients with metatastic prostate cancer.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- New phase II data presented at the American Society of Clinical Oncology (ASCO) annual meeting show that treatment with atrasentan Abbott Laboratories' investigational, selective endothelin-A receptor...

Cell Genesys reports encouraging long-term survival data in phase II trial.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- Cell Genesys, Inc. (CEGE) reported encouraging long-term survival data from a phase II multicenter clinical trial of GVAX prostate cancer vaccine, which demonstrates a dose-dependent trend toward...

Cellular Genomics patents process for discovering enzyme inhibitors.
June 21, 2002... 2002 JUN 21 - (NewsRx.com & NewsRx.net) -- Cellular Genomics, Inc., (CGI) announced that it has been awarded U.S. Patent No. 6383790 by the United States Patent and Trademark Office for general methods for discovering enzyme inhibitors, as well...

New drug holds promise to block clots.
June 28, 2002... 2002 JUN 28 - (NewsRx.com & NewsRx.net) -- The first study of a new drug designed to block blood clot formation showed no major adverse effects in people with stable coronary artery disease, according to a report in Circulation: Journal of the...

Liposomal daunorubicin encapsulation reduces excessive cytotoxic activity.
June 28, 2002... 2002 JUN 28 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United Kingdom have shed new light on the effects of encapsulating the anticancer agent daunorubicin (DNR) in a liposomal coating. Dr....

Grapefruit juice does not affect amprenavir levels.
June 28, 2002... 2002 JUN 28 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The HIV protease inhibitor amprenavir may be safely taken with grapefruit juice, researchers in France report. Dr. D. Demarles and colleagues at the...

Anti-inflammatory drugs fail to prevent a hereditary colon cancer.
June 28, 2002... 2002 JUN 28 - (NewsRx.com & NewsRx.net) -- The anti-inflammatory drug sulindac may not have the colon cancer prevention properties once hoped for, according to Johns Hopkins Kimmel Cancer Center researchers. Results of a 4-year study,...

Prevention regimens in Africa need to deter women from breastfeeding.
June 28, 2002... 2002 JUN 28 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Treatment to prevent mother-to-child transmission of HIV in developing countries needs to be accompanied by ways to deter women from breastfeeding, researchers...

Levofloxacin best choice for treating resistant staph infections.
June 28, 2002... 2002 JUN 28 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The fluoroquinolone levofloxacin may be the best option for dealing with methicillin-resistant Staphylococcus aureus (MRSA) infections, researchers in...