Drug Week articles from July 2004

Drug Week archives from July 2004

Special protocol assessment agreed on for approval-enabling study of Ranexa.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- CV Therapeutics, Inc., (CVTX) announced that the company and the U.S. Food and Drug Administration (FDA) have reached written agreement on a protocol for a clinical trial of Ranexa (ranolazine), which,...

Application filed for European marketing approval of RSR13 (efaproxiral).
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Allos Therapeutics, Inc., (ALTH) announced that it has filed a Marketing Authorization Application (MAA) with the European Medicines Agency (EMEA) to market RSR13 (efaproxiral) as an adjunct to whole...

Ceplene 36-month malignant melanoma survival data published.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Maxim Pharmaceuticals, Inc., (MAXM) announced that the 36-month patient follow-up data from the M01 phase III study of Ceplene (histamine dihydrochloride) as a combination therapy to treat advanced...

Study links chromium picolinate supplementation, reduced carbohydrate cravings.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Results of a new double-blind, placebo-controlled human clinical trial found daily supplementation with chromium picolinate significantly reduced some key symptoms of atypical depression. People...

Risperdal reduces acute bipolar mania symptoms as early as day 3 of treatment.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Results from a controlled, large-scale, clinical trial show that when Risperdal (risperidone) was used to treat patients with acute bipolar mania, a statistically significant reduction of symptoms as...

Millennium, partner begin trial with INTEGRILIN (eptifibatide) Injection.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Millennium Pharmaceuticals, Inc., (MLNM) and Schering-Plough Corp. (SGP) announced the initiation of a multicenter, phase IIIb, clinical trial to evaluate the benefit of INTEGRILIN when administered...

Fusion proteins overcome the hurdle of leukemia cell chemoresistance.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Fusion proteins overcome the hurdle of leukemia cell chemoresistance. According to recent research from the United States, "chemoresistance is a common cause of treatment failure in patients with...

Liver function test results for naltrexone patients may be misleading.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Liver function test results for naltrexone patients may be misleading. "Many clinicians appear to be concerned about the potential hepatotoxicity of the opiate antagonist naltrexone (NTX) and this...

Actin and its C-terminal peptide act as cofactors with adenovirus proteinase.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Actin and its 11-amino acid C-terminal peptide act as cofactors with the adenovirus proteinase. "Actin bound to the adenovirus proteinase (AVP) with a lower equilibrium dissociation constant, 4.2...

SnET2 NDA accepted by FDA with priority review designation.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Miravant Medical Technologies (MRVT), a pharmaceutical development company specializing in PhotoPoint photodynamic therapy (PDT), announced that the U.S. Food and Drug Administration (FDA) has accepted...

Study will investigate safety, efficacy of PFTA as adjunct to Visudyne therapy.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- QLT Inc. (QLTI) has entered into a cooperative research and development agreement (CRADA) with the National Eye Institute (NEI) to study the effects of preservative-free triamcinolone acetonide (PFTA)...

Allergy vaccine disrupts structure of calcium-binding allergen.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Researchers have developed an allergy vaccine that acts by disrupting the three-dimensional structure of the cross-reactive calcium-binding allergen, Phl p 7. According to a study from Austria,...

Cytochrome P450 isoforms involved in oxatomide metabolism identified.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Cytochrome P450 isoforms involved in oxatomide metabolism have been identified. "Oxatomide is an antiallergic drug used for the treatment of diseases mediated by type 1 allergy," scientists in Japan...

Lung proteome within airway mucosa following allergen challenge investigated.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Scientists explore the context of the lung proteome within the airway mucosa following allergen challenge in a recent issue of the Journal of Proteome Research. "The lung proteome is a dynamic...

Nanocrystalline silver cream potentially therapeutic for skin inflammations.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Nanocrystalline silver cream is potentially therapeutic for skin inflammations. "The anti-inflammatory activity of topical nanocrystalline silver cream was assessed and compared with the effects of...

Total IgE measurement is valid surrogate for antigen-specific IgE.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Measurement of total IgE is a valid, simple surrogate for antigen-specific IgE analysis. "Due to its dependence on IL-4 and IL-13 production, IgE production is frequently used to assess the type 2...

AApoAII amyloidosis induced by various heterogeneous amyloid fibrils.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- AApoAII amyloidosis was induced by various heterogeneous amyloid fibrils. "Preformed amyloid fibrils accelerate conformational changes of amyloid precursor proteins and result in rapid extension of...

CD36 overexpression correlates with A-beta, not with Alzheimer disease.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- CD36 overexpression in human brain correlates with beta-amyloid deposition but not with Alzheimer disease. "Scavenger receptors recently have been related to Alzheimer disease, although it is still...

Neurodegeneration and amyloid plaques occur in transgenic Drosophila.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Scientists have studied age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila. According to recent research published in the Journal of Neuroscience,...

Olfactory dysfunction occurs in mice overexpressing human tau protein.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Olfactory dysfunction occurs in transgenic mice overexpressing human tau protein. According to a study from the United States, "Disorders of olfaction are among the first clinical signs of...

Oxidative stress and mitotic changes necessary for Alzheimer disease progression.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Oxidative stress and mitotic changes are both necessary for Alzheimer disease progression. According to a study from Case Western Reserve University, "There are many lines of evidence showing that...

Seeding specificity in amyloid growth induced by heterologous fibrils.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Seeding specificity in amyloid growth can be induced by heterologous fibrils. "Over residues 15-36, which comprise the H-bonded core of the amyloid fibrils it forms, the Alzheimer disease plaque...

Link suspected between soccer and amyotrophic lateral sclerosis.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Soccer, neurotrauma, and amyotrophic lateral sclerosis appear to be related. According to recent research from Germany, "Trauma has long been hypothesized but never proven to be a risk factor for...

Study initiated for ferumoxytol under company's agreements with NCI.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Advanced Magnetics, Inc., (AVM) announced that the National Cancer Institute's Cancer Imaging Program (NCI/CIP) has initiated the first clinical study under the clinical trial agreement for ferumoxytol...

Platelet-derived growth factor stimulates pericyte recruitment to tumors.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Platelet-derived growth factor stimulates pericyte recruitment to tumors. "Platelet-derived growth factor (PDGF) receptor signaling participates in different processes in solid tumors, including...

NIH supports phase I clinical trial of DNA-based anthrax vaccine.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Vical, Inc., (VICL) announced that the National Institute of Allergy and Infectious Diseases (NIAID) of the U.S. National Institutes of Health (NIH) has advised the company it will support a phase I...

Public-private partnership extends Dutch-American cooperation in biodefense.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- IQ Corp., a biopharmaceutical company based in The Netherlands, and the U.S. Navy Medical Research Center (NMRC) have entered into a Cooperative Research and Development Agreement (CRADA) to develop...

B. anthracis antigens for testing anthrax immunity identified.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Scientists have identified Bacillus anthracis extractable antigens that are suitable for testing anthrax immunity. According to published research from Israel, "Three extractable Bacillus anthracis...

Antimicrobial drug development declining.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Despite an increasing need for antimicrobial drugs, drug development in this area in the United States is declining. According to recent research published in the journal Clinical Infectious...

Thyroliberin controls murine candidosis.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Exogenous thyroliberin (TRH) significantly reduces candidosis severity in a murine model. TRH "is one of the hormones which affect immunologic processes," researchers in Poland explained. In a...

Development and marketing agreement signed for novel formulation of amoxicillin.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Par Pharmaceutical Companies, Inc., (PRX) has signed a definitive agreement with Advancis Pharmaceutical Corporation (AVNC) to develop and market a novel formulation of the antibiotic amoxicillin. ...

New antifungal agents offer prospects for treatment.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- New antifungal agents offer prospects for treatment. "As invasive fungal infections in immunocompromised patients become increasingly important, the field of antifungal chemotherapy continues to...

PIDDosome activates caspase-2 in response to genotoxic stress.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- The PIDDosome is a protein complex implicated in the activation of caspase-2 in response to genotoxic stress. According to a study from Switzerland, "Apoptosis is triggered by activation of...

Short-stemmed modular shoulder prosthesis safe and effective.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- A novel shoulder prosthesis is safe and effective for arthritis patients. According to recent research from the Netherlands, "[b]etween 1994 and 2001, a short-stemmed modular shoulder prosthesis was...

Diaphragm patch facilitates placement of AbioCor implantable replacement heart.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- A diaphragm patch can facilitate the placement of artificial hearts. "One of the concerns when placing a total artificial heart is whether the device will fit in the thoracic cavity without...

Strattera provides full-day relief from ADHD symptoms in systematic study.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Strattera (atomoxetine HCl), approved for attention-deficit/hyperactivity disorder (ADHD), significantly reduced symptoms of ADHD for the full day in the first systematic study of Strattera treatment in...

Strattera now available in the United Kingdom.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Strattera (atomoxetine HCl), a nonstimulant treatment for attention-deficit hyperactivity disorder (ADHD), is now approved for use in the United Kingdom and will be available by mid-July. Before...

Anti-HIAP antibodies prevalent in systemic sclerosis patients.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Anti-HIAP antibodies are often found in systemic sclerosis patients. According to recent research from Italy, "[s]erum antibodies against human intracisternal A-type particle (HIAP) endogenous...

Link between vaccinations and autoimmune disease reviewed.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Scientists review the link between vaccinations and autoimmune disease in a recent issue of the European Journal of Dermatology. "The potential association between vaccination and autoimmune...

MFG-E8 mediates removal of apoptotic germinal center B cells.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- The protein MFG-E8 mediates efficient removal of apoptotic germinal center B cells. "Apoptotic cells expose phosphatidylserine and are swiftly engulfed by macrophages," scientists in Japan...

Biotechnology company named on list of technology industry's top 100 companies.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Perlegen Sciences, Inc., has been named by Red Herring magazine as one of the technology industry's top 100 companies. Red Herring's editors examined more than 600 private global companies'...

Mosquito-larvicidal toxin produced by Bacillus sphaericus crystallized.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Researchers have crystallized the mosquito-larvicidal binary toxin produced by Bacillus sphaericus. According to a study from the United States, "The Bacillus sphaericus binary toxin is expressed...

Viral Antigens enters strategic collaboration.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Meridian Bioscience, Inc., (VIVO) announced that its wholly owned subsidiary, Viral Antigens, Inc., (VAI) has entered into a strategic collaboration with Viral Therapeutics, Inc., (VTI), Ithaca, New...

Diversity of Bartonella in rodents of Thailand determined.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Scientists have determined the prevalence and diversity of Bartonella in rodents of northern Thailand. According to a study from the United States and Thailand, "We report results of the first...

Collagenous matrices release exogenous growth factors for tissue regeneration.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Collagenous matrices release exogenous growth factors for tissue regeneration. According to researchers in Japan, "we have investigated the use of natural and synthetic collagenous matrices as...

Albumin-containing sol-gel glasses developed.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Albumin-containing sol-gel glasses have been developed and characterized. In a recent study from Italy, "[g]lasses incorporating increasing amounts of bovine serum albumin were prepared by sol-gel...

DNA-encapsulating polysulfone hollow microspheres developed.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Novel DNA-encapsulating microspheres may be useful for environmental monitoring. In a recent study from Japan, "[p]olysulfone hollow microspheres encapsulating DNA were prepared using a...

Four pH-dependent formation constants for free PSA elucidated.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Four pH-dependent formation constants for free PSA was elucidated. "Both the free and total PSA had been reported to be pH- and temperature-labile. We have introduced two submodels to describe the...

Vaccines for the prevention of diseases caused by potential bioweapons.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Scientists review vaccines for the prevention of diseases caused by potential bioweapons in a recent issue of the journal Clinical Immunology. According to researchers in the United States, "The...

Seroquel combined with mood stabilizer may improve mania symptoms.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Patients with mania associated with bipolar disorder receiving Seroquel (quetiapine fumarate) adjunct therapy in combination with lithium or divalproex achieved significantly greater rates of response...

Accuracy of blood glucose estimation by children with diabetes studied.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Researchers report results of a study to determine the accuracy of blood glucose estimation by children with diabetes in a recent issue of Psychological Reports. According to recent research from...

Company announces new intravenous gene-delivery method.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Mirus Bio Corp. announced the development of Pathway IV gene delivery, a new method to efficiently deliver therapeutic genes to muscle via the blood stream. According to Mirus, this technique...

Calcium and thrombin trigger factors that spark endothelial cell proliferation.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Calcium and thrombin trigger factors that spark endothelial cell proliferation. "Platelet concentrates (PCs) constitute new biological mediators used in osseous reconstructive surgery. In this...

Secca clinical patient registry for bowel incontinence treatment.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Curon Medical, Inc., (CURN), the manufacturer of the Secca system for the treatment of Bowel Incontinence (BI), announced the launch of its new Secca Clinical Patient Registry for Bowel Incontinence, an...

Relation between stress and circulating levels of S100B protein reported.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Scientists report the relation between stress and circulating levels of S100B protein in a recent issue of the journal Brain Research. According to research from Italy, "It has been proposed that...

Follow-up data presented on autologous hemoderivative vaccine.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- A team of researchers from France and the U.S. presented at the 2004 annual meeting of the American Society of Clinical Oncology follow-up data on an autologous hemoderivative vaccine administered to...

Nanoparticle form of paclitaxel is active in patients who failed taxane therapy.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Abraxis Oncology, a division of American Pharmaceutical Partners, Inc. (APP) (NASDAQ: APPX) said that results from a 106-patient Phase II study of Abraxane in patients with advanced breast cancer whose...

Researchers develop better understanding of tamoxifen resistance.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- A new study by researchers at Georgetown University's Lombardi Comprehensive Cancer Center may have implications for the thousands of breast cancer patients who develop resistance to antiestrogen drugs...

Survivin, Bcl-2, p53 and bax expression increased in breast carcinoma.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Survivin, Bcl-2, p53 and bax expression are increased in breast carcinoma. According to published research from Turkey, "Survivin is a recently discovered member of the family of proteins that...

Vaccine containing multiple antigens generates higher immune response.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- A breast cancer vaccine containing multiple antigens may boost a patient's clinical response rate because this strategy increases the chances that the immune system will respond to at least one antigen....

Women treated for breast malignancies receive poor postoperative education.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Women treated for breast malignancies receive poor postoperative education. According to published research from Finland, "in this retrospective survey we investigated the recall of breast cancer...

FDA warns against women using domperidone to increase milk production.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- In response to reports that women may be using an unapproved drug, domperidone (Motilium; manufacturer: Janssen), to increase lactation, the U.S. Food and Drug Administration (FDA) is warning...

Bridge Pharmaceuticals Corporation launched.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- SRI International announced the launch of Bridge Pharmaceuticals Corporation. Bridge recently closed $3.5M through a Series A investment round led by WI Harper Group. Additional investors include...

Company acquires rights to novel proteasome inhibitors and related technology.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Millennium Pharmaceuticals, Inc., (MLNM) announced that it has signed a research agreement with Harvard University and Professor E.J. Corey for a family of proteasome inhibitors and a related chemical...

Company opens new preclinical pharmaceutical inhalation facility.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Huntingdon Life Sciences, a provider of preclinical research services, announced the official launch of its new pharmaceutical inhalation-safety testing facility at its location in East Millstone, New...

Company to acquire controlling interest in HBBenda.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Hubei Pharmaceutical Group (HBEI) has entered into a formal agreement to acquire a 60% controlling interest in Hubei Tongji Benda Ebei Pharmaceutical Co., Ltd., (HBBenda), located in Guangshui City,...

Drug discovery company announces completion of two validation milestones.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- SGX (Structural GenomiX, Inc.) announced the completion of its installation of a high-throughput structural biology facility for Eli Lilly and Company (LLY) and the achievement of two significant...

Hospira expands manufacturing capacity.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Hospira, Inc., (HSP) has acquired from Fresenius Kabi its manufacturing facility in Clayton, North Carolina. The acquisition includes a 100,000 square-foot facility and equipment, the...

ImClone shares jump on favorable data on cancer drug.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Shares of biotechnology company ImClone Systems Inc. rose sharply June 7, 2004, after the company reported positive data on its Erbitux cancer drug. ImClone told the American Society of Clinical...

Integrated BioPharma delivers update on paclitaxel API.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Integrated BioPharma, Inc.'s, (INB) subsidiary, Paxis Pharmaceuticals, Inc., was expected to submit a drug master file for its paclitaxel API (active pharmaceutical ingredient) to the U.S. Food and Drug...

Nutraceutical/pharmaceutical company selects Central American distributor.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Pharmessen Scientific, Inc., has entered into an agreement with Pharmacorp Internationale S.A. for the distribution of Pharmessen's products in Central America. While terms of the agreement were...

Pharmaceutical firm announces move to new facility.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Anadys Pharmaceuticals, Inc., (ANDS) announced the relocation of its facilities in San Diego, California. "We are extremely excited to move to this state-of-the-art facility that was specially...

Pharmaceuticals firm acquires two new drugs for ADHD, completes financing.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Alliant Pharmaceuticals, Inc., - an emerging pediatric specialty pharmaceutical company, announced that it has acquired the exclusive U.S. marketing rights to two products for attention deficit...

SEC finds Schering-Plough unit made bribes through charity.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Federal regulators said June 9, 2004, that the Polish subsidiary of pharmaceutical company Schering-Plough Corp. paid $76,000 to influence decisions by a government official in Poland by making...

Stem cell company announces plans for new facility.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Cryo-Cell International, Inc., (CCEL) announced that it has entered into a 10-year lease with Harrod Properties, Inc., to construct a customized, nearly 18,000 square-foot state-of-the-art good...

Strategic Alliance formed for pulmonary delivery technologies.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- SkyePharma PLC has entered into a strategic alliance with Vectura Limited in the area of pulmonary delivery technologies. Through this alliance SkyePharma will acquire rights to use Vectura's...

Lipid-mobilizing factor protects tumor cells from oxidative damage.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Lipid-mobilizing factor plays a role in protecting tumor cells from oxidative damage. "Lipid-mobilizing factor (LMF) is produced by cachexia-inducing tumors and is involved in the degradation of...

Mechanism of caffeine as psychomotor stimulant proposed.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Researchers have proposed a mechanism of caffeine as a psychomotor stimulant. According to recent research from Sweden, "The popularity of caffeine as a psychoactive drug is due to its stimulant...

Epidermal growth factor receptor and Cerb-B2 fail to predict tongue cancer.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Epidermal growth factor receptor and Cerb-B2 fail to predict tongue cancer. "Squamous cell carcinoma (SCC) of the tongue is sometimes associated with local recurrence and regional metastases despite...

Men with vitamin D receptor polymorphisms are at risk for prostate cancer.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Men with vitamin D receptor polymorphisms are at risk for prostate cancer. According to a study from Taiwan, "recent molecular epidemiological studies have shown that the inherited polymorphisms of...

Role of hMLH1 and HPP1 in adenocarcinomas determined.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- The roles of the hMLH1 and HPP1 genes in adenocarcinoma have been elucidated. "Using methylation-specific real-time PCR," researchers in Germany "determined the prevalence of aberrant methylation in...

Cancer risk lowered in those taking statins to prevent heart attacks.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- People taking statins to lower their cholesterol and ward off heart attacks may have even more reason to keep swallowing their medicine: New data suggests the drugs also may fight off cancer. The...

Warfarin does not prevent bladder cancer formation.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Warfarin does not prevent bladder cancer formation. "There has been growing interest in studying the biological effects of certain drugs and their potential to reduce the risk of various cancers....

Calcitonin gene hypermethylation marks the progress of leukemia.
July 2, 2004... 2004 JUL 2 - (NewsRx.com & NewsRx.net) -- Calcitonin gene hypermethylation marks the progress of leukemia. According to a study from Byelarus, "methylation of the 5'-region of the calcitonin gene was investigated in bone marrow and...