Drug Week articles from January 2002

Drug Week archives from January 2002

Pediatric Oxacillin Use Carries Heightened Risk of Liver Damage.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Oxacillin is more risky for pediatric patients than other antibiotics, researchers warn. Dr. Nizar F. Maraqa and colleagues at the University of Florida...

Osteoprotegerin Reduces Bone Degradation.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The protein osteoprotegerin (OPG) may help prevent bone damage in patients suffering from multiple myeloma, researchers say. "Multiple myeloma is a B-cell...

Interleukin-2 Does Not Increase Virus-Specific T-Cell Activity.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The use of the immunostimulatory cytokine interleukin (IL)-2 during HIV treatment has little effect on HIV specific immune activity, researchers in the United...

Cyclosporine A Reduces Chemotherapy Resistance.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Texas have found a way to improve the efficacy of chemotherapy drugs used to treat high-risk acute myeloid leukemia (AML) patients. ...

Interferon-(alpha) With Cytarabine Effective For Early Treatment.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Spain say that the combination of interferon and a form of cytarabine can produce positive results in patients with newly diagnosed chronic...

Studies Say Creatine Is OK.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- Athletes who use the energy-building supplement creatine can train without raising their risk of injury, researchers say. "Now we are seeing trends; everybody is finding similar results," said...

ADP Receptor Blockade Reduces Platelet Clumping.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Drugs that block adenosine 5'-diphosphate (ADP) receptors may be useful for preventing thrombotic events, according to researchers in Texas. Nancy A....

Long-Term Cognitive and Functional Improvements Shown With Memantine.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- Clinical data, demonstrating the ability of the investigational compound memantine to preserve cognition and daily functioning and delay the rate of decline in patients with advanced Alzheimer disease,...

Consensus Pharmaceuticals Names New CEO.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- Consensus Pharmaceuticals has appointed John G. Schulte as chief executive officer. Most recently, Schulte was president and CEO of Somnus Medical Technologies, a publicly held medical device...

NeoTherapeutics Appoints Former Pfizer Clinical Research Exec To NeoOncoRx Scientific Advisory Board.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- NeoTherapeutics, Inc. (NEOT) announced today the appointment of Dilip J. Mehta, MD, PhD, to the NeoOncoRx Scientific Advisory Board. Dr. Mehta spent 15 years at Pfizer Inc,. as senior vice president,...

West Pharmaceutical Services Hires Drug Delivery President.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- West Pharmaceutical Services, Inc., (WST) has named Michael Myers, PhD, as president of the drug delivery systems division. Myers most recently held the position of executive vice president,...

Experimental Cancer Drug Beta-Alethine Produces Promising Responses.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- Wilson Miller, PhD, MD, LifeTime Pharmaceuticals, Inc., and principal investigator of the Beta LT clinical trials at McGill University/Jewish General Hospital presented results of the study in Orlando,...

Intravesical Neoquin Shows Antitumor Activity Against Superficial Disease.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- NeoTherapeutics, Inc., announced that research studies, undertaken by the Cancer Research Unit at the University of Bradford in England, suggest that Neoquin (E09) might be effective as a treatment for...

Arsenic Trioxide Shown Safe For A Variety Of Patients.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- Data from clinical trials and postmarketing experience presented at the 43rd annual meeting of the American Society of Hematology show that Trisenox (arsenic trioxide) injection can be used to safely...

Anastrozole More Effective Than Tamoxifen In Early Disease.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- New data presented at the December 2001 San Antonio Breast Cancer Meeting demonstrate for the first time that an aromatase inhibitor Arimidex (anastrozole) is significantly more effective and has a...

Significant Survival Advantages For Combination Chemotherapy Patients.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- U.S. Oncology announced that data presented by two network-affiliated physicians at the 24th San Antonio Breast Cancer Symposium underscore that the chemotherapy combination of Xeloda (capecitabine)...

Outstanding Response Rates In Imatinib Mesylate-Treated Patients.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- New data show that use of the Novartis drug Gleevec (imatinib mesylate) in patients with newly diagnosed chronic myeloid leukemia (CML) in the early chronic phase can result in high cytogenetic...

CogScreen, Invivodata Collaborate To Offer Real-Time Subjective Data Collection.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- Invivodata, Inc., and CogScreen have created an alliance to provide clinical trial sponsors with both cognitive and subjective data collection methods. This combination potentially could help...

Positive Phase I/II Clinical Results Of Novel Narcotic Announced.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- Pain Therapeutics, Inc., announced positive Phase I/II results with PTI-801, a novel narcotic painkiller. Pain Therapeutics, Inc., believes PTI-801 is a safer version of immediate release...

Early Vardenafil Phase III Data Report Positive Results.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- Results of the first pivotal Phase III data released on vardenafil, an investigational phosphodiesterase-5 (PDE-5) inhibitor, found up to 85% reported improvement across a broad population of patients...

AAMC Issues New Guidelines On Financial Conflicts Of Interest.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- The Association of American Medical Colleges (AAMC) has released the first report of its Task Force on Conflicts of Interest in Clinical Research "Protecting Subjects, Preserving Trust, Promoting...

Phase I Results Of Tezacitabine Provide Rationale For Phase II Study.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- Results of a Phase I study of tezacitabine (FMdC) for relapsed or refractory acute leukemias were presented at the 43rd Annual American Society of Hematology Meeting and Exposition on December 10,...

Gliadel Wafer Provides Clinical Benefit With Acceptable Safety.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- Guilford Pharmaceuticals, Inc., announced in December (2001) that the Oncologic Drugs Advisory Committee (ODAC) voted 8 to 5 that Gliadel Wafer (polifeprosan 20 with carmustine implant) provides...

Repifermin Demonstrates Excellent Safety Profile In Phase IIa Clinical Trials.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- Human Genome Sciences, Inc., announced that the results of two Phase IIa clinical trials demonstrate the safety of systemically administered repifermin (keratinocyte growth factor-2, KGF-2). Both...

Perrigo Gets FDA Nod On Treatments For Yeast Infections, Migraines.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- The Perrigo Company (PRGO) has received approval from the U.S. Food and Drug Administration (FDA) to manufacture and market over-the-counter tioconazole ointment and migraine formula tablets. These...

Interallied Group Changes Name To Pilot Therapeutics Holdings.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- Interallied Group, Inc., has reincorporated under the laws of Delaware and changed its name to Pilot Therapeutics Holdings, Inc. The company's stock, which formerly traded on the Nasdaq...

West Pharmaceutical Services Consolidates Divisions.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- West Pharmaceutical Services, Inc., (WST) will consolidate operations into two divisions, which will be named the pharmaceutical systems and drug delivery systems divisions. This change follows...

Discovery Laboratories And Quintiles To Commercialize Surfaxin.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- Discovery Laboratories, Inc., and Quintiles Transnational Corp. have signed a sales and marketing agreement to commercialize in the United States Discovery's Surfaxin (lucinactant), a novel, humanized...

Cellegy Issued Patent for Testosterone Gel in the United States.
January 11, 2002... 2002 JAN 11 - (NewsRx.com & NewsRx.net) -- The U.S. Patent and Trademark Office has approved the patent "Penetration Enhancing and Irritation Reducing Systems" covering methods of topically administering sex hormones, including testosterone and...

Modified Reverse Transcriptase Inhibitors Effective Against Resistant Viral Strains.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United States say that they have improved the efficacy of a group of HIV reverse transcriptase inhibitors. "In an effort to elucidate a...

Filgrastim May Help Infants With Neutrophil Dysfunction.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Granulocyte colony-stimulating factor (G-CSF), also known as filgrastim, may be helpful for treating newborns with "quantitative and qualitative neutrophil...

Busulfan Dose Targeting Improves Pediatric Engraftment.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Individualized pharmacokinetic testing should be used to fine-tune circulating levels of busulfan in children undergoing bone marrow transplantation,...

Oxaliplatin-Based Chemotherapy Safe, Effective.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - A chemotherapy regimen based on oxaliplatin can help patients suffering from high-risk non-Hodgkin's lymphoma, according to researchers in the United Kingdom....

Rifampicin Dose Adjustments Can Prevent Treatment Failure.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Ineffective rifampicin-based treatment in pulmonary tuberculosis patients can be caused by inadequate serum levels of the drug, researchers in Tennessee say....

Steroid Nasal Sprays Seem To Speed Recovery In Sinus Infections.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- A new Duke University Medical Center study shows that patients with sinus infections recover faster and manifest symptoms for a shorter period of time when using fluticasone, a steroid nasal spray, in...

Risperidone Cuts Relapse Rate Over Haloperidol.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- A second-generation antipsychotic drug lowers the risk of relapse in patients with schizophrenia by nearly half, according to a team of researchers, led by psychiatrists at Washington University School...

Study Reveals Higher Than Expected Rate Of Drug Resistance.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- ViroLogic, Inc., announced that the first national assessment of HIV drug resistance has revealed that 78% of HIV patients with measurable levels of virus in their blood are infected with an HIV strain...

Tipranavir, First Nonpeptidic Protease Inhibitor Introduced.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- Data demonstrated the antiretroviral activity of tipranavir in HIV positive patients whose first protease inhibitor (PI)-containing regimen was failing. Tipranavir is the first nonpeptidic protease...

Epoetin Alfa Evaluated In HIV Patients On Antiretroviral Therapy.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- The results of an interim analysis of an open-label study to assess the effect of once-weekly (QW) dosing of Procrit (Epoetin alfa) versus three-times-weekly (TIW) dosing in HIV positive patients...

Ferrous Sprinkles Useful For Pediatric Treatment.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Food with iron sprinkles can be used to treat anemic infants in developing countries, researchers say. "Standard therapy for anemia in infants is ferrous...

Boehringer Ingelheim Submits New Drug Application for Tiotropium.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- Boehringer Ingelheim Pharmaceuticals, Inc., has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration for Spiriva (tiotropium), the first once-a-day inhaled bronchodilator...

Antibiotics That Target DNA Effective Against Drug Resistant Bacteria.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- Genelabs Technologies, Inc., presented research results on its novel antibacterial compounds at the December 2001 41st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in...

New Compound Has The Power To Transform Beta-Lactam Antibiotics.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, senior medical writer - "Destruction of (beta)-lactam antibiotics by Class A and Class C (beta)-lactamase enzymes is a major cause of drug resistance in bacterial infections,"...

Novel Mechanism Of Iseganan HCL Presented At Conference.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- IntraBiotics Pharmaceuticals, Inc., announced new data on its lead compound iseganan HCl at the 41st annual meeting of the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), held...

Ibuprofen Neutralizes Aspirin's Heart-Protective Effects, Study Says.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- The popular pain reliever ibuprofen blocks the heart-protecting effects of aspirin, according to a study that sounds a warning for people who take both medicines. "It would not do you a lot of...

Pfizer Settles With Texas Woman In Diabetes Drug Case.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- A woman who said her liver was destroyed by Pfizer, Inc.'s, recalled diabetes drug, Rezulin, still faces the prospect of a transplantation. But her attorneys say a settlement reached with the drug...

U.S. FDA Creates New Subcommittee On Drug Safety, Risk Management.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration (FDA) has created a new Drug Safety and Risk Management Subcommittee to the Advisory Committee for Pharmaceutical Science. The new subcommittee is comprises...

Elidel Cream Cleared for Marketing in U.S.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration (FDA) has granted marketing approval for Novartis Pharmaceuticals' Elidel (pimecrolimus) Cream 1%, the first nonsteroid prescription cream for mild-to-moderate...

Positive Results From Trial Of Nasally Administered Apomorphine.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- Nastech Pharmaceutical Company, Inc., reported the results of a Phase II clinical trial in 184 men with erectile dysfunction (ED) that concluded its nasally administered apomorphine formulation...

Lansoprazole Relieves Heartburn Faster Than Omeprazole.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- Study data showed that the proton pump inhibitor (PPI) lansoprazole provides faster relief of heartburn than omeprazole in patients with erosive esophagitis. The study, which examined more than...

General Accounting Office Probes Tainted Medical Research.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- Universities and federal health officials must do more to prevent financial conflicts that could taint biomedical research and harm human subjects, a congressional review says. The study by the...

Replagal Patent Suit Dismissed.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- The U.S. District Court of Delaware will dismiss the patent litigation Genzyme Corp. and Mount Sinai School of Medicine brought against TKT Transkaryotic Therapies, Inc. (TKTX) in connection with TKT's...

Novel Tetracyclines Advance Treatment Options.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- At the 41st annual meeting of the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Paratek Pharmaceuticals, Inc., researcher Dr. Michael Draper presented recent milestones in...

Comparison Study Of MS Therapies Shows Two Reduce Relapses.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- Only Copaxone (glatiramer acetate for injection) and Betaseron (interferon (beta)-1b) significantly reduced the mean annualized number of relapses compared with the untreated group of...

FDA Approves Tigan Capsules NDA.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- King Pharmaceuticals, Inc., (KG) has received approval from the U.S. Food and Drug Administration (FDA) for its new drug application (NDA) for Tigan (trimethobenzamide hydrochloride) 300 mg capsules....

Too Much Vitamin A May Increase Risk Of Hip Fracture.
January 18, 2002... 2002 JAN 18 - (NewsRx.com & NewsRx.net) -- Long-term intake of a diet high in retinol, a vitamin A compound, may promote the development of osteoporotic hip fractures in postmenopausal women, according to new research. Diane Feskanich,...

Zidovudine Resistance Mutations Increase Abacavir Resistance.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Mutations that confer zidovudine resistance to HIV strains can also confer or augment resistance to abacavir, possibly limiting choices for effective drug...

Novel Cephalosporin Effective Against Staph-Related Endocarditis.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Switzerland say that a novel antibiotic shows promise in treating disorders caused by drug-resistant staphylococcus bacteria. Jose M....

Azithromycin Partially Effective For Mycobacterium Avium Prophylaxis.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The antibiotic azithromycin provides limited protection against Mycobacterium avium-induced illness in HIV patients failing highly active antiretroviral...

Critics Find Fault With Merck-Medco's Generics Program.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- Like many pharmacists employed by drug companies, Rich Douglass visits dozens of doctors every month to tout the benefits of specific medications. Douglass isn't promoting any hot, new brand-name...

Recombinant Factor VIIa Inhibits Fibrinolysis.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Europe say that recombinant factor VIIa treatment for hemophiliacs can be beneficial in several different ways. "Recombinant factor VIIa...

Rituximab Augments Other Anticancer Drugs.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Germany have provided new information on the therapeutic mechanisms of a potent antilymphoma drug. "Monoclonal antibody IDEC-C2B8...

FDA Tries to Stem Drug Mix-Ups.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- The epilepsy drug Lamictal looks and sounds too much like the antifungal pill Lamisil. How much? At least 22 times, pharmacies have confused the names and dispensed the wrong drug - causing three...

Protease Inhibitors Aid Oral Candidiasis Treatment.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Protease inhibitor (PI)-based antiretroviral HIV treatment is the best option for patients suffering from oral candidiasis, researchers in Italy report. ...

FDA Approves Clarinex for Seasonal Allergic Rhinitis.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- Schering-Plough Corp.'s Clarinex (desloratadine) 5 mg tablets has received marketing clearance from the U.S. Food and Drug Administration for the treatment of seasonal allergic rhinitis (SAR) in adults...

Clarithromycin Active In Vitro With Low Resistance.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- Findings released December 18, 2001, at the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), held in Chicago, Illinois, offer valuable insight into the activity of...

Emisphere Technologies Names President and Chief Operating Officer.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- Emisphere Technologies, Inc., (EMIS) has appointed Alan William Dunton, MD, to the newly created position of president and chief operating officer. Dunton joins Emisphere from The Janssen Research...

ICN Names Executive Vice President Corporate Relations.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- ICN Pharmaceuticals, Inc., (ICN) has appointed Alan Charles as executive vice president, corporate public relations. Charles will be responsible for public, investor and community relations at ICN...

Switzerland First European Country to Approve Non-Steroidal Topical Treatment.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- The Swiss Intercantonal Office for the Control of Medicines (IKS/OICM) has approved Fujisawa GmbH's Protopic (tacrolimus ointment) for the treatment of children and adults suffering from moderate to...

Positive Phase III Results For Oritavancin Antibiotic Announced.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- InterMune, Inc., announced results of a Phase III clinical trial demonstrating that oritavancin, its glycopeptide antibiotic to treat Gram-positive bacterial infections, cut the treatment time in half...

Decitabine Combined Gleevec Helps Circumvent Resistance.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- SuperGen, Inc., announced that data from a preclinical study identified the anticancer compound decitabine as one of two novel compounds that, in separate combination therapy regimens, could overcome...

Data On Compounds Active Against Candida And Aspergillus Presented.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- Genelabs Technologies, Inc., announced that data on its novel antifungal compounds were presented at the 41st annual meeting of the Interscience Conference on Antimicrobial Agents and Chemotherapy...

FDA Declines ImClone Cancer Drug Application.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration has declined to accept ImClone Systems, Inc.'s, application for its new cancer drug, Erbitux. Erbitux has been touted as a possible blockbuster drug that could...

Ramoplanin Active In Vitro Against Intestinal Bacteria.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- In a presentation at the 41st meeting of the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in December (2001) researchers have reported the antibacterial effects of...

New Class Of Drugs Associated With Significant Quality-of-Life Benefits.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- According to a recent study, topical immunomodulators (TIMS), the newest class of drugs to treat moderate-to-severe eczema, show that more than 60% of adults, children and toddlers improved in areas in...

Oxazolidinone Demonstrate Potency Against Drug Resistant Pathogens.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- Worldwide data presented at the 41st annual meeting of the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), in December (2001), show that AstraZeneca's new oxazolidinone...

R&D Funding for 2002 Buffeted by External Forces.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- Total R&D expenditures in the United States are expected to increase about 3.5% to $285.6 billion in 2002, according to the annual Battelle-R&D Magazine research and development forecast. Three...

Epigallocatechin Gallate Reduces Nicotine-Induced Legionella Susceptibility.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Florida say that they have found an agent capable of reversing nicotine-induced susceptibility to Legionella pneumophila infection. ...

Proteasome Inhibitor Shows Promise For Patients With Refractory Disease.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- Millennium Pharmaceuticals, Inc., announced preliminary findings of an ongoing Phase II clinical trial of its investigational drug LDP-341 (formerly known as PS-341) in patients with multiple myeloma...

Positive Trial Results For Intraocular Drug Delivery.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- BioSante Pharmaceuticals, Inc., announced results of a preclinical trial demonstrating the effectiveness of its calcium phosphate nanoparticulate (CAP) delivery system for the administration of drugs...

Patient Enrollment In Phase III Study Of Iseganan Completed.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- IntraBiotics Pharmaceuticals, Inc., announced that it has completed patient enrollment in the second of three planned pivotal Phase III trials of its iseganan HCl antibiotic to reduce the severity of...

Vitamin A Intake Levels Reaffirmed As Safe And Beneficial.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- The Council for Responsible Nutrition (CRN), one of the dietary supplement industry's leading trade associations, in consultation with independent osteoporosis and vitamin A experts, responded to the...

Gatifloxacin Eradicates Common Bacteria In Middle Ear Fluid.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- Preliminary results from ongoing clinical and bacteriologic studies designed to demonstrate the effectiveness of fluoroquinolones in treating pediatric ear infections have shown that Tequin...

Study Shows Antibiotic Effectiveness As Adjunctive Treatment.
January 25, 2002... 2002 JAN 25 - (NewsRx.com & NewsRx.net) -- Results of a study show that patients with periodontitis respond more favorably to a combined treatment of scaling and root planing (SRP) together with Arestin, than to SRP alone. Arestin, a...