Drug Week articles from December 2001

Drug Week archives from December 2001

Statins Called "New Aspirin" by Heart Conference Presenter.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- by C.W. Henderson, senior medical correspondent - "Statins are the new aspirin." That's the quote to be remembered from the American Heart Association (AHA) Scientific Sessions 2001 conference in...

Human Genome Sequencing Will Have Profound Impact On 21st Century Medicine.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Chromosome analysis, gene mapping, and the complete sequencing of the human genome provide an anatomic basis for all aspects of clinical medicine, and are likely to change medicine in many ways over the...

Enteric-Coated Didanosine Linked To Milder Gastrointestinal Effects.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - A delayed-release version of the antiretroviral drug didanosine (ddI) is much easier on patients than the standard form of the drug, researchers in...

Novel Technique Developed For Measuring Antiretroviral Toxicity.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United States and Italy have devised a novel method for measuring mitochondrial toxicity caused by antiretroviral HIV drugs. ...

Premier Databases To Support FDA Drug Safety Surveillance.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- To improve its knowledge about the use and effects of new drugs once they have reached the market, the U.S. Food and Drug Administration (FDA) will tap into the most extensive hospital database in the...

Novel Drugs May Improve Survival in Advanced Heart Disease.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- by C.W. Henderson, senior medical correspondent - Several late-breaking clinical trials reported at an international conference are good news for heart patients. Reported at the American Heart...

Newly Found Estrogen Role In Males Might Lead To Contraceptive For Men.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Newly found estrogen role in males might lead to contraceptive for men Researchers tapping into the estrogen pathway that regulates fertility in males have found two independent roles of the...

Kidney Disease In African-Americans Focus Of Study.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- by C.W. Henderson, senior medical correspondent - No one knows which drugs work best to prevent kidney disease linked to hypertension in African-Americans. So Janice G. Douglas, chief of the...

LJP 394 Reduces Renal Complications.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- La Jolla Pharmaceutical Company presented additional data from an earlier Phase II/III clinical trial of its clinical candidate for systemic lupus erythematosus (lupus), LJP 394, at the 2001 World...

Zindaclin Cleared For Marketing In U.K.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Access Pharmaceuticals, Inc., has announced that Strakan, Ltd., the worldwide licensee of its ResiDerm technology, has received marketing authorization in the United Kingdom for Zindaclin. The product...

Neurochem Receives $1.4 Million FDA Grant For Fibrillex.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Neurochem, Inc., (NRM) has received a $1.4 million grant from the U.S. Food and Drug Administration (FDA) for a pivotal Phase II/III study of Fibrillex, which is currently under way. The company also...

Chest Pain Drug Tested for Heart Attack Prevention.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- by C.W. Henderson, senior medical correspondent - A drug used to treat chest pain is being tested to see if it can reduce the risk of heart attack in patients with chronic angina. The drug,...

Arthur Mandell Becomes President And Chief Executive Officer Stemron Corp.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Stemron Corp. has named Arthur M. Mandell president and chief executive officer. Mandell brings more than 20 years of leadership experience in both the pharmaceutical and biotechnology sectors,...

NeoTherapeutics Names New Vice President Of Pharmaceutical Development.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- NeoTherapeutics, Inc., (NEOT) has appointed Ashok Gore, PhD, as vice president, pharmaceutical development. Gore has more than 30 years of experience with many leading pharmaceutical companies and will...

PharmaNet Names Drug Safety Expert To Lead Pharmacovigilance Group.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- PharmaNet has appointed Jan Willem van der Velden, MD, FFPM, to vice president, global safety and pharmacovigilance. van der Velden will be based in the company's Amersfoort, Netherlands, office. ...

Scion Pharmaceuticals Names Pravin R. Chaturvedi President And CEO.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Scion Pharmaceuticals, Inc., has appointed Dr. Pravin R. Chaturvedi as president and chief executive officer. Prior to joining Scion, Chaturvedi was responsible for lead evaluation at Vertex...

Drug for Heart Rhythm Disturbance Tested for Sudden Cardiac Death Prevention.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- by C.W. Henderson, senior medical correspondent - An atrial fibrillation drug now is being tested for ventricular fibrillation. Sudden death, a leading cause of death in North America accounting...

Abbott Recognized For Continuous Improvement In Environmental Issues.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Abbott Laboratories (ABT) has received the 2001 Governor's Pollution Prevention Award for Continuous Improvement for its achievements in a healthy and safe environment. Abbott is the only health care...

Anastrozole Compared With Tamoxifen For Advanced Disease.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- According to authors of a multicenter study, Arimidex (anastrozole) should be the first choice, first-line therapy for postmenopausal women with hormone-sensitive advanced breast cancer. ...

Rolling Biologics License Application Filing For Erbitux Now Complete.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- ImClone Systems, Inc., (IMCL) has completed its rolling biologics license application (BLA) submission to the U.S. Food and Drug Administration (FDA) for approval of Erbitux (formerly known as IMC-C225)...

orBec Enters Phase II Clinical Trial.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Corporate Technology Development, Inc., (CTD) has initiated a Phase II clinical trial to evaluate the efficacy of orBec in treating Crohn disease. This is the second clinical trial that CTD has...

Previously Unknown Antibiotic Identified In Fish.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- A Brief Communication in Nature reports the discovery of a previously unknown family of antibiotics - piscidins - in fish. Piscidins are peptide antibiotics and are made in the fish mast cells,...

Foundation Responds To Acetaminophen Liver Toxicity Research.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- The Aspirin Foundation of America (AFA) objected to press reports of a recent study from the University of Colorado Health Sciences Center in Denver, Colorado on acetaminophen toxicity. The study,...

OxyContin Maker Readies Ad Campaign Against Painkiller's Abusers.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- The manufacturer of a powerful painkiller fast gaining a reputation as a deadly recreational drug is starting an advertising campaign to discourage illegal use of prescription drugs. As of November...

New Therapies Proving Effective For Millions.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Eczema, a chronic skin disease that causes itching and inflammation and resulting redness, swelling, cracking, weeping, and scaling, affects 15 million Americans, many of them children. Speaking...

Ciprofloxacin Can Cause Seizures In Some People.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Medical advisors to the Epilepsy Foundation warned that fluoroquinolone antibiotics such as Cipro (ciprofloxacin), which are the first line of defense for anthrax, can in certain circumstances induce...

Hopkins Sanctions Scientist For Cancer Drug Trial.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Johns Hopkins University sanctioned a researcher who tested experimental cancer drugs on patients in India without the approval of a university review board, the school announced. The sanctions,...

Genzyme General Receives Complete Response Letter For Fabrazyme BLA.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Genzyme General (GENZ), a division of Genzyme Corp., has received a complete response letter from the U.S. Food and Drug Administration (FDA) related to its application to market Fabrazyme (agalsidase...

Long-Term Data Confirms Benefit Of Enzyme Replacement Therapy.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Transkaryotic Therapies, Inc., announced results from an open-label extension of its six-month pivotal trial of Replagal (agalsidase alfa) enzyme replacement therapy for the treatment of Fabry disease....

Revenue Growth Highlights Lynx's Third Quarter Results.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Lynx Therapeutics, Inc., (LYNX) reported revenues of $5.8 million for the third quarter of 2001, a 68% increase over third quarter 2000 revenues of $3.4 million. For the 9-month periods ended September...

Schering-Plough Launches Peg-Intron And Rebetol Combination Therapy in U.S.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Schering-Plough Corp. has launched combination therapy using Peg-Intron (peginterferon alfa-2b) powder for injection and Rebetol (ribavirin, USP) capsules for treating chronic hepatitis C. Rebetol...

Phase II Calcimimetics Data Is Promising.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- NPS Pharmaceuticals, Inc. announced that various investigators of its licensee Amgen, Inc., presented positive data on the drug candidate AMG 073 at medical meetings during October 2001. The data...

Trisenox Recommended For Approval In Europe.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Cell Therapeutics, Inc., (CTI) has received a recommendation for approval from the Committee for Proprietary Medicinal Products (CPMP) for Trisenox (arsenic trioxide) injection in the treatment of...

Metabasis Awarded SBIR Grant to Discover Novel Agents.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Metabasis Therapeutics, Inc., has been awarded a $153,103 Phase I grant by the U.S. National Institute of Diabetes and Digestive and Kidney Diseases. The grant, titled "Adenosinergic Therapy for...

Microcide And Althexis Rename Merged Company Essential Therapeutics.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Microcide Pharmaceuticals, Inc., (MCDE) and the Althexis Co., Inc., announced that at a special meeting held October 24, 2001, Microcide shareholders approved the merger of Microcide Pharmaceuticals and...

Orphan Medical Announces Xyrem Response Accepted For Review By FDA.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration (FDA) has accepted the Orphan Medical, Inc., response, in the form of an amendment, to the approvable letter for Xyrem (sodium oxybate) oral solution of July 2,...

Pharmacyclics Regains Rights To Optrin From Alcon.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Pharmacyclics, Inc., (PCYC) has regained worldwide rights to develop and market Optrin (motexafin lutetium) injection for the potential photodynamic treatment of age-related macular degeneration (ARMD)...

Methylnaltrexone Significantly Reverses Morphine Side Effects.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Progenics Pharmaceuticals, Inc., announced statistically significant, positive results from Phase II clinical studies of methylnaltrexone (MNTX), an investigational drug designed to reverse the...

Unigene Awarded Federal Grant To Continue Development of Oral PTH.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Unigene Laboratories, Inc., (UGNE) has been awarded a small business innovation research grant from the U.S. National Institutes of Health to further develop an oral parathyroid hormone (PTH) product...

FDA Approves Enhanced Pregnancy Prevention Program For Accutane.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration (FDA) has approved an enhanced version of Roche's Pregnancy Prevention Program for Women on Accutane (PPP), according to Hoffmann-La Roche, Inc. The revised...

Bioject Signs License And Development Agreement With Alkermes.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- Bioject Medical Technologies, Inc., (BJCT) and Alkermes, Inc., (ALKS) have entered into a licensing and development agreement to develop up to three undisclosed drug compounds as proprietary products...

De Novo And ChemOvation Announce Collaboration On Chemistry Services.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- De Novo Pharmaceuticals, Ltd., and ChemOvation, Ltd., have entered into a collaborative agreement for the provision of synthetic chemistry services directed toward certain De Novo drug discovery...

New Drugs Hold Promise For Safety, Effectiveness In Treatment.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- A multicenter, international pilot study of two new drugs to treat patients with rheumatoid arthritis has found the drugs to be safe and effective in treating the disease. Larry Moreland, MD,...

Drug Helps Smokers with Heart Disease Quit.
December 7, 2001... 2001 DEC 7 - (NewsRx.com & NewsRx.net) -- by C.W. Henderson, senior medical correspondent - The drug Bupropion SR is a highly effective and well-tolerated smoking cessation aid for individuals with cardiovascular disease (CVD). That's...

Dexamethasone Can Reduce CD4 Cell Loss.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The anti-inflammatory steroid dexamethasone has a protective effect on CD4 cells in HIV patients, researchers report. Previous studies had shown that...

S28463 Effectively Treats Mycobacterium bovis Infection.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Canada say that they have identified a potential new weapon in the arsenal of antimycobacterial treatments. "It has been shown that...

FDA Approves New Class Of Therapy For Rheumatoid Arthritis.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- The first in a new class of therapy for rheumatoid arthritis has won federal approval although studies show Kineret promises just modest effectiveness. The U.S. Food and Drug Administration (FDA)...

Celecoxib Does Not Increase Risk Of Cardiovascular Adverse Events.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- An analysis of safety data, representing over 13,000 patients from the new drug application (NDA) and 8000 patients in the Celecoxib Long-term Arthritis Safety Study (CLASS), supports that Celebrex...

Valdecoxib Effective In Treating OA And RA With Fewer Gastrointestinal Side Effects.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- Results from two Phase III clinical studies of the potent investigational COX-2-specific inhibitor valdecoxib showed that it demonstrated similar efficacy to the conventional non-steroidal...

Prehospital Administration of Reteplase Saves Time To Treatment.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- A study presented November 14, 2001, at the American Heart Association's Scientific Sessions 2001 appears to demonstrate the benefits of the clot-dissolving agent Retavase (reteplase) in the...

Risedronate Sodium Once A Week As Effective As Daily Dose.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- A once-a-week, 35 mg dose of Actonel (risedronate sodium tablets) was as effective as 5 mg of Actonel daily at increasing bone mineral density (BMD) in women with postmenopausal osteoporosis (PMO),...

Moxifloxacin May Make Effective Isoniazid Supplement.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The fluoroquinolone antibiotic moxifloxacin may be useful for neutralizing tuberculosis infections, researchers say. Nacer Lounis and colleagues at the...

Promising Results From Fondaparinux Trial Reported.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- The results of the Phase IIb PENTUA study comparing fondaparinux - the first of a new class of selective synthetic factor Xa inhibitors - with the low-molecular-weight heparin enoxaparin in the...

Cell Model Of Oxidative Stress Valuable For Screening Drugs.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- Panacea Pharmaceuticals, Inc., presented new findings on its Alzheimer drug development program November 13, 2001, at the 31st Annual Meeting of the Society for Neuroscience, held in San Diego,...

Phase III CARISA Trial Meets Primary Endpoint.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- CV Therapeutics, Inc., has announced that its Phase III CARISA trial of ranolazine met its primary efficacy endpoint. With patients on a background antianginal therapy, ranolazine statistically...

Schering AG Acquires Worldwide Rights For Dermatitis Drug.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- Schering AG, Germany (SHR, SCH), has acquired worldwide rights to further develop and market the compound ABT-281 for atopic dermatitis and all other potential dermatological diseases from Abbott...

New Transmucosal Technology Being Evaluated.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- Transmucosal Technology Ltd. (TTL), a joint venture between Atrix Laboratories, Inc., (ATRX) and Elan Corp., PLC (ELN) has submitted an investigational new drug application (INDA) to the U.S. Food and...

Quintiles And Capsugel Expand Alliance for Capsule Capabilities.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- Quintiles Transnational Corp. and Capsugel, a division of Pfizer, Inc., have expanded their current alliance to now include U.S.-based formulation and manufacturing services. Building upon the...

MAXIA Presents Data On Novel Small Molecule Anticancer Agents.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- MAXIA Pharmaceuticals, Inc., presented results of preclinical studies on three novel classes of anticancer compounds that are in development for treatment of solid human tumors, including non-small...

NEO-339 Improves Attentional Deficits, Learning, And Memory In Animals.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- NeoTherapeutics, Inc., presented data at the Society for Neuroscience meeting in San Diego, California, November 13, 2001, showing that NEO-339 improves attentional deficits as well as learning and...

Novel Drug Candidates Address Cognitive Deficits Of Psychotic Patients.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- ACADIA Pharmaceuticals presented data on its proprietary small molecules that offer the unique potential to treat all symptoms of schizophrenia including cognitive deficits The presentation was...

Valsartan Reduces Total Heart Failure Hospitalizations.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- Researchers from the University of Minnesota Medical School presented new findings from the Valsartan Heart Failure Trial (Val-HeFT) during the American Heart Association (AHA) Scientific Sessions...

Sleuthing, A Required Skill For Rheumatologists.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, senior medical writer - Prescription drugs, abused drugs, and herbal supplements can produce toxicities in humans that mimic rheumatic syndromes, according to Dr. Hal Mitnick, New...

Two Phase III Clinical Trials Of Topical Drug Initiated Concurrently.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- NexMed, Inc., announced that it has initiated two Phase III clinical studies on Alprox-TD, its proprietary cream under development for treating erectile dysfunction (ED). The Phase III program,...

United Therapeutics Shows Continued Growth In Revenues In Third Quarter.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- United Therapeutics Corp. (UTHR) has announced financial results for the third quarter ended September 30, 2001. "We are pleased to announce that United Therapeutics ended its third quarter in...

IntraDose Receives Nonapprovable Letter From FDA.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- Matrix Pharmaceutical, Inc., (MATX) has received a nonapprovable letter from the U.S. Food and Drug Administration (FDA) for IntraDose (cisplatin/epinephrine) Injectable Gel. Matrix submitted a New...

Hormonal Study Shows Valsartan Significantly Reduces Severity Marker.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- Results of the largest neurohormonal study ever conducted in patients with heart failure demonstrate that the angiotensin II receptor blocker (ARB) valsartan significantly reduces plasma brain...

Intravenous Amiodarone Demonstrated To Be More Effective Than Lidocaine.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- Data presented November 14, 2001, at the American Heart Association's (AHA) Scientific Sessions 2001 in Anaheim, California, demonstrates that the antiarrythmic agent i.v. amiodarone is almost twice as...

EcoNail Technology Holds Potential For Revolutionizing Treatment.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- EcoNail, an investigational, lacquer-based topical antifungal treatment incorporating MacroChem Corporation's SEPA technology, shows sixfold greater nail penetration by an antifungal drug than an...

Celecoxib Associated With Reduced Hospitalizations And Office Visits.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- Data from the largest, worldwide study ever conducted in osteoarthritis (OA), the Successive Celecoxib Efficacy and Safety Study (also known as the SUCCESS-1 trial), were presented at the scientific...

Second Study Confirms Celecoxib Is Comparable With Rofecoxib.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- Findings from a second study confirmed that 200 mg once daily of Celebrex (celecoxib capsules) is comparable with 25 mg once daily of rofecoxib in providing effective relief from the pain of...

Acadia Nominates 5-HT2A Inverse Agonist For Clinical Development.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- Acadia Pharmaceuticals has nominated a potent and highly selective 5-HT2A inverse agonist for clinical development as a novel treatment for psychosis. The company's clinical candidate, ACP-103,...

FDA Purchases LeadScope Enterprise And ToxScope Toxicity Databases.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration (FDA) has purchased LeadScope, Inc.'s, Enterprise software and the ToxScope toxicity databases to assist in its "in silico" toxicology assessment. Earlier...

InnaPhase Signs Agreement With Pfizer For Drug Metabolism, Pharmacokinetic Data.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- Pfizer, Inc., has signed a worldwide license agreement to implement InnaPhase Corp.'s Watson Laboratory Information Management System (LIMS). The announcement expands Pfizer's use of the Watson...

IKK-2 Inhibitor Blocks Disease Progression In Preclinical Model.
December 14, 2001... 2001 DEC 14 - (NewsRx.com & NewsRx.net) -- Celgene Corporation researchers presented data November 14, 2001, at the 65th Annual Scientific Meeting of the American College of Rheumatology (ACR) on a preclinical study of novel small molecule...

Protease Inhibitors Ineffective Against Pneumocystis Bacteria.
December 21, 2001... 2001 DEC 21 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Contrary to previous reports, HIV drugs have little effect on Pneumocystis carinii microorganisms, researchers in the United States warn. "Human...

Quetiapine Adjunctive Therapy Offers Benefits Over Monotherapy.
December 21, 2001... 2001 DEC 21 - (NewsRx.com & NewsRx.net) -- Results from a first-ever controlled study evaluating efficacy and safety of antipsychotic treatment in adolescent bipolar disorder demonstrate that adding the atypical antipsychotic Seroquel...

Investigational Drug Shows Promise Against Debilitating Disease.
December 21, 2001... 2001 DEC 21 - (NewsRx.com & NewsRx.net) -- Results of a recently published study show that the investigational drug pegvisomant normalized concentrations of the hormone insulin-like growth factor-I (IGF-I) in 97% of patients with acromegaly...

Catalytic Antioxidant Delays Onset Of Autoimmune Diabetes.
December 21, 2001... 2001 DEC 21 - (NewsRx.com & NewsRx.net) -- Incara Pharmaceuticals Corporation's (INCR) prototype catalytic antioxidant, AEOL 10113, significantly delayed onset of elevated blood sugar in a mouse adoptive transfer model of type 1 diabetes. ...

Lerdelimumab Prevents Excessive Postoperative Scarring.
December 21, 2001... 2001 DEC 21 - (NewsRx.com & NewsRx.net) -- Cambridge Antibody Technology (CAT) announced the 6-month follow-up results from a Phase II clinical trial using CAT-152 (lerdelimumab; human anti-TGF(beta)2 monoclonal antibody) in patients undergoing...

Synercid Effective Against Drug-Resistant Enterococcus.
December 21, 2001... 2001 DEC 21 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United States and Europe say that quinupristin/dalfopristin (Synercid, Aventis) can be used to treat patients with drug-resistant...

Low-Dose Acenocoumarol May Be Effective Over The Long Term.
December 21, 2001... 2001 DEC 21 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The anticoagulant acenocoumarol may have long-term therapeutic benefit for patients suffering from sickle cell disease, researchers in the Netherlands say. ...

Interleukin-2 Improves Lymphocyte Function.
December 21, 2001... 2001 DEC 21 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The cytokine interleukin (IL)-2 can restore proper lymphocyte function to HIV patients, researchers say. "Increased susceptibility to apoptosis and loss of...

Study Shows Pentostatin Is Useful As Part Of Less-Toxic Regimen.
December 21, 2001... 2001 DEC 21 - (NewsRx.com & NewsRx.net) -- SuperGen, Inc., (SUPG) announced that data from a study of its anticancer compound pentostatin (Nipent) shows that it is a major component of a novel, less-toxic regimen that also includes...