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Intranasal Vaccine Demonstrates Safety, Immunogenicity.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
by N.R. Saltmarsh, staff medical writer - A new Shigella flexneri 2a vaccine delivered intranasally could offer as much protection as live vaccines already studied in humans and warrants further...
Growth Factor Inhibitor - Gemcitabine Combination Blocks Tumor Growth.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
by Sonia Nichols, senior medical writer - Pancreatic cancer proliferation and metastasis can be curbed with a new drug combination that blocks epidermal growth factor receptor (EGFR) signaling.
...
Shifting Liquid Crystals May Serve As Personal, Portable Chemical Sensors.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
Liquid crystals formed from molecules weakly tethered to a nanotextured surface could form the basis of highly sensitive, wearable sensors to detect personal exposure to certain synthetic organic...
Adjuvant Speeds Relief For Pollen Sufferers.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
by N.R. Saltmarsh, staff medical writer - A new allergy vaccine for pollen sufferers is more effective when given with monophosphoryl lipid A (MPL), a Th1-stimulating adjuvant, researchers in...
Grant Awarded For Rapid Sequencing Of Disease-Transmitting Mosquito.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
The U.S. National Institute of Allergy and Infectious Diseases (NIAID) announced a $9 million award to help reveal the genetic secrets of malaria, a complex disease responsible for up to three...
Novel in silico Method Predicts Cellular Protein Interactions.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
A novel computational approach developed by Hybrigenics for predicting cellular protein interactions across whole organisms delivers substantial advantages in sensitivity and accuracy over current...
Two-Dose Hepatitis B Vaccination Expected To Reduce Costs In Long Run.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
by Sonia Nichols, senior medical writer - Even though the cost of a two-dose regimen of hepatitis B vaccine may be more for adolescents in the short term, in the long run, it could save money,...
Virus-Like Particles Induce Antibody, Cytokine Responses In Chimps.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
by N.R. Saltmarsh, staff medical writer - Chimpanzees vaccinated with virus-like particles (VLPs) of human papillomavirus (HPV) are able to mount antibody and cytokine responses to various HPV...
Noninvasive, Early Detection Procedure May Aid Early Finding Of Cancer.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
A model incorporating ultrasound and optics technology may have application in early detection of cancer.
The analytical model that took Texas A&M University biomedical engineer Lihong Wang six...
Clarithromycin Extended-Release Tablet Receives FDA Approval.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
Abbott Laboratories announced that it has received U.S. Food and Drug Administration (FDA) approval of a new seven-day indication for Biaxin(R) XL (clarithromycin extended-release tablets) for the...
Positive Phase II Trial Outcomes With Mucoadhesive Liquid Technology.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
Access Pharmaceuticals, Inc. (AKC) announced results from its Phase II randomized clinical study of OraRinse(TM) for the prevention and treatment of mucositis, or inflammation of the mucosal...
Bayer Anticholesterol Drug May Be Linked To 52 Deaths.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
Bayer AG said on August 13, 2001, that its Baycol anticholesterol drug may be linked to 52 deaths, five days after Germany's biggest drug maker announced a voluntary recall of the drug.
The...
Milestone Reached In Phase I Enzyme Replacement Therapy Study.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
BioMarin Pharmaceutical, Inc. (BMRN) announced that it has completed the 24-week treatment stage of its Phase I clinical trial of recombinant human N-acetylgalactosamine 4-sulfatase (rhASB), an...
Study Reports On Viremia Suppression By Quadruple Combination Therapy.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
Quadruple combination HIV therapy with efavirenz (brand name: Sustiva; DuPont Pharmaceuticals), a non-nucleoside reverse transcriptase inhibitor (NNRTI), plus nelfinavir and two nucleoside reverse...
Oral Parathyroid Hormone Has Promising Preclinical Results.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
Emisphere Technologies, Inc. (EMIS), announced that an oral delivery formulation of its parathyroid hormone (PTH) fragment produces serum PTH levels comparable to those found following injection in...
European Commission Opposes Funding Human Cloning And Stem Cell Research.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
The European Commission will not finance any projects involving the cloning of humans or stem cell research and hopes all 15 European Union members will forbid work in such areas, its research...
FDA Approves Diagnostic Kit.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
INOVA Diagnostics, Inc. and Luminex Corporation announced that INOVA's new QUANTA Plex(TM) ENA Profile 4, based on Luminex's open-platform LabMAP(TM) system, has recently received 510(k) approval...
First Cloned Sheep Born In North America, Protein Production Targeted.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
Infigen, Inc. announced the birth of Pickles, the first lamb to be cloned in North America.
Born July 22, 2001, the female makes Infigen the only organization in North America to have...
Spring-Based Retracting Needle Syringe Receives FDA Approval.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
The Med-Design Corporation (MEDC) congratulated BD (BDX) on receiving clearance from the U.S. Food and Drug Administration (FDA) to market a new safety-engineered, spring-based, retracting needle...
New Class Of Antibody Drug Candidate Discovered.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
MorphoSys AG (Mor) and ProChon Biotech, Ltd. announced the discovery of a novel antibody lead resulting from their collaboration initiated in June 2000.
The antibody, representing a new class...
States Seek To Bring Down Drug Costs.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
Bedeviled by sharply rising prescription drug costs, states across the U.S. are seeking new strategies for wringing discounts from pharmaceutical companies.
At the same time, the states are...
Patient Enrollment Completed In Motexafin Gadolinium Phase II Trial.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
Pharmacyclics, Inc. (PCYC) announced that it has completed patient enrollment in a Phase II clinical trial to evaluate its lead investigational product, Xcytrin(R) (motexafin gadolinium) injection,...
Receptor Linked To Pain, Blood Pressure, And Other Functions Discovered.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
Synaptic Pharmaceutical Corporation (SNAP) announced that it has been awarded a U.S. patent (6,262,246) entitled "DNA Encoding Mammalian Neuropeptides FF (NPFF) Receptors and Uses Thereof" to cover...
New Enzyme Replacement Therapy Available In European Union.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
Transkaryotic Therapies, Inc. (TKTX) announced the European Commission has granted marketing authorization for Replagal(TM) (agalsidase alfa) - an enzyme replacement therapy for long-term treatment...
Phase I Trial Of Enzyme Inhibitor And Gemcitabine Initiated.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
Vion Pharmaceuticals, Inc. (VION) has begun enrollment in a Phase I clinical trial of its investigational anticancer agent Triapine(R) in combination with the anticancer agent gemcitabine, for...
Phase II Clinical Trial Of Enzyme Inhibitor Initiated.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
Vion Pharmaceuticals, Inc. (VION) has initiated a Phase II clinical trial of its anticancer agent Triapine(R) for patients with metastatic breast cancer.
The study will be conducted at the...
Novel Immunosuppressant Now Comes In Tablet Formulation.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
Wyeth-Ayerst Laboratories announced that the first solid formulation of its transplant immunosuppressant, Rapamune(R) (sirolimus), is now available in the United States.
The new 1-mg tablet...
Personalizing Medicine: Tests Optimize Treatments For Major Diseases.
September 5, 2001... 2001 SEP 5 - (NewsRx.com & NewsRx.net) --
deCODE Genetics (DCGN) and Affymetrix, Inc. announced that they have signed a collaboration to develop DNA-based tests to predict the responsiveness of individual patients to treatments for common...
Therapy With Natural Vessel Inhibitor May Lessen Vision Loss.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
by Sonia Nichols, senior medical writer - If animal model experiments eventually pan out, patients diagnosed with age-related macular degeneration (ARMD) may some day benefit from receiving...
Experimental Drug Inhibits Corneal Angiogenesis And Tumor Growth.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
by Sonia Nichols, senior medical writer - Tests of a new tubulin-binding drug called BTO-956 show it inhibits both growth factor-induced corneal angiogenesis and the growth of rodent cancer cells....
Rivers A Significant Transmission Source For Campylobacter Species.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
by N.R. Saltmarsh, staff medical writer - Analysis of New Zealand recreational and drinking water sources reveals that Campylobacter contamination of water sources poses a potential threat to...
Health Officials Identify 10 Stem Cell Labs Eligible For U.S. Research Funds.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
The U.S. National Institutes of Health has identified 10 companies and research laboratories with embryonic stem cell colonies that the Bush administration says are eligible for federal research...
Lamivudine More Cost Effective Than Interferon For Hepatitis B.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
by Sonia Nichols, senior medical writer - Using a decision-analysis model, analysts at two major pharmaceutical and biotechnological firms have decided lamivudine monotherapy is more cost effective...
Collaboration Scales Up Computer Power To Study Protein Folding.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
Massive computing power and biology are coming together in a big way through a cooperative research and development agreement (CRADA) announced by IBM and the U.S. Department of Energy's Oak Ridge...
Neurons Implanted In Damaged Brain Tissue Show Function.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
An imaging study of neurons implanted in damaged areas of the brains of stroke patients in the hopes of restoring function has shown the first signs of cellular growth, say University of Pittsburgh...
Breakthrough Mouse Model Has Both Amyloid Plaques And Neurofibrillary Tangles.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
Researchers at Mayo Clinic in Jacksonville, Florida, have successfully bred mice exhibiting amyloid plaques and neurofibrillary tangles, the two key pathologic hallmarks of Alzheimer disease (AD)....
BufferGel Prevents Pregnancy, STDs In Animal Models.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
by N.R. Saltmarsh, staff medical writer - A new spermicidal and microbicidal gel may have useful applications for the prevention of pregnancy and sexually transmitted diseases (STDs) in humans.
...
Mechanized Microfluidic Device Interacts With Red Blood Cells.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
Silicon microteeth that open and close like jaws have been developed at Sandia National Laboratories, affiliated with the U.S. Department of Energy.
The microjaws fit in a microchannel about...
Company Receives Grant For Spinal Cord Injury Regeneration.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
Acorda Therapeutics announced that it has been awarded a Phase I Small Business Innovation Research (SBIR) grant by the U.S. National Institutes of Health to study the repair of damaged nerves...
Agreement Strengthens Gene Therapy Program.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
Amsterdam Molecular Therapeutics B.V., Amsterdam, The Netherlands (AMT), announced the signing of an exclusive Sublicense and Research Agreement with Xenon Genetics Inc., a drug discovery company...
Health Experts Form Latino Diabetes Coalition.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
In response to the escalating diabetes epidemic among Latino Americans, Aventis Pharmaceuticals has joined with eight Latino health and diabetes experts to form the Latino Influencer Network (LIN)....
Advisory Committee Approves 7.5% Icodextrin Solution For Peritoneal Dialysis.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
Baxter Healthcare Corporation reported that the Cardiovascular and Renal Drugs Advisory Committee to the U.S. Food and Drug Administration (FDA) unanimously recommended approval of Extraneal (7.5%...
Drug Significantly Arrests Tumor Growth with Minimal Side Effects, Study Shows.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
A study published in the September 2001 issue of the Journal of Urology is the first of its kind to show a significant effect of a new class of drugs that may stabilize progressive, recurrent...
First Structural Insight Into New Class Of Protease Cancer Targets Presented.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
Corvas International, Inc. (CVAS) reported that company scientists and collaborators at the Max-Planck Institute of Biochemistry in Martinsried, Germany, have solved the three-dimensional molecular...
Current Lines May Get FDA's Approval.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
The fact that colonies of human embryonic stem cells are grown with the help of mouse cells won't block their eventual use in people as long as scientists meet well-known federal safety rules,...
Fertility Clinic To Give Embryos To Harvard University For Research In Major Deal.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
A fertility clinic will give embryos to Harvard University in a deal that could make the university one of the world's top suppliers of embryonic stem cells.
Boston IVF, an organization of...
New Test Detects Bacteria Faster On Food Processing Surfaces.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
In a study that simulated analysis of samples from equipment surfaces in food processing plants, IGEN International, Inc.'s Pathigen(TM) tests for Salmonella and Listeria and supplied, in just one...
Caspase Inhibitors Reduce Damage In Animal Model.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
Idun Pharmaceuticals, Inc. presented preclinical evidence that caspase inhibitors may have therapeutic potential for the treatment of heart disease.
The data were presented at the American...
Phase I Study Evaluates Novel Respiratory Nasal Spray.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
Inspire Pharmaceuticals, Inc. announced that an investigational new drug application (IND) has been filed with the U.S. Food and Drug Administration for INS37217 respiratory nasal spray for the...
New Dietary Supplement Ingredient Available In U.S.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
Merck KGaA announced that its U.S. specialty chemicals affiliate, EM Industries, Inc., of Hawthorne, New York, will immediately begin marketing L-methylfolate, or Metafolin(TM), a derivative of...
Simple Method For Rapid Amplification Of Circular DNA Developed.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
Molecular Staging, Inc., announced that, together with Amersham Pharmacia Biotech, the two companies have developed a simple method of using Rolling Circle Amplification to copy circular DNA for...
2-Methoxyestradiol Blocks Cell-Cycle Progression/Inhibits Growth.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
Oncology Sciences Corporation (OSC) announced the publication of findings that 2-methoxyestradiol (2-ME), a naturally occurring hormone, inhibits the growth of human prostate cancer cells.
The...
Pilot Study Of PH-10 Concludes With Promising Results.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
Photogen Technologies, Inc., announced the final results of its initial clinical investigator trial examining the use of the company's unique highly selective photoactive agent PH-10 together with...
Anhydrovinblastine Completes Phase I Safety Study.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
Prescient NeuroPharma, Inc. (PRE) announced that it has successfully completed a Phase I clinical trial demonstrating the safety and tolerability of Anhydrovinblastine (AVLB).
"The final...
New Method Engineers HIV Zinc Finger Proteins.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
Recently published research describes a new system that permits the rapid engineering of zinc finger proteins (ZFPs) able to bind in a highly specific fashion to more diverse DNA sequences than was...
Combination Therapy Receives FDA Approval.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
Schering-Plough Corporation announced that the U.S. Food and Drug Administration (FDA) has approved Peg-Intron (peginterferon alfa-2b) Powder for Injection for use in combination therapy with...
Device Allows For High-Speed Processing Of Diversified Food Products.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
SureBeam Corporation - innovator of the nation's first electronic pasteurization system for food - announced that it has been awarded a U.S. patent for a major technological advancement that allows...
Expanded Enrollment Approved For Trial Of Ventricular Assist System.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
Thoratec Corporation reports that, based on a review of the preliminary data from the REMATCH trial, the U.S. Food and Drug Administration (FDA) has approved an Investigational Device Exemption...
Machine That Simulates A Warm Human Body Keeps Kidney Functioning.
September 12, 2001... 2001 SEP 12 - (NewsRx.com & NewsRx.net) --
A machine that simulates a warm human body kept a kidney functioning for almost 24 hours in a test of a technique researchers say could longer preserve donated organs.
The team at the...
Tenofovir Can Protect Macaque Infants.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
by Michael Greer, senior medical writer - The HIV reverse transcriptase inhibitor tenofovir (or PMPA) can protect newborn primates from the simian form of HIV and may be able to perform the same...
Microbicide Shows Potential Against Herpes Simplex.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
by N.R. Saltmarsh, staff medical writer - A vaginal microbicide shows promise in preventing transmission of herpes simplex and possibly other sexually transmitted diseases, researchers in Canada...
Breakthrough Allergen Tests Will Help Millions Worldwide.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
ABC Research Corporation announced it is using tests developed by the University of Nebraska's Food Allergy Research & Resource Program in cooperation with the Neogen Corporation of Lansing,...
Tetravalent Vaccine Protects Monkeys.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
by N.R. Saltmarsh, staff medical writer - A newly constructed chimeric vaccine against dengue virus/yellow fever achieves antibody levels in rhesus monkeys
similar to those found in animals...
Annotations Of 89% Of Human Proteome Released.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
Accelrys, Inc. announced that it has used GeneAtlas to extend the number of functional annotations of the human proteome by almost 20% over those publicly available.
These new annotations...
FDA Approves Start Of Phase III Clinical Trial With E2F Decoy.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
Corgentech, Inc. announced that the U.S. Food and Drug Administration (FDA) has approved its investigational new drug application (IND) for the initiation of a Phase III clinical trial to evaluate...
FDA Approves Zoledronic Acid Treatment.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
Novartis has received marketing approval from the U.S. Food and Drug Administration (FDA) for Zometa (zoledronic acid for injection), a new generation intravenous (IV) bisphosphonate for the...
Genetic Screening Test Now Available In The U.S.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
Orchid BioSciences, Inc. (ORCH) announced that the cystic fibrosis (CF) genetic screening test Elucigene CF29 has been launched for use by CLIA-approved laboratories in the United States.
...
Sertraline HCl Approved For Long-Term Use.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
Pfizer, Inc. announced that it has received U.S. Food and Drug Administration (FDA) approval for long-term use of Zoloft (sertraline HCl) in the treatment of post-traumatic stress disorder (PTSD)....
Therapeutic Vaccine To Start Testing In Phase II Study.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
AVANT Immunotherapeutics, Inc. announced today the start of a placebo-controlled Phase II study of its cholesterol management vaccine (CETi-1) in approximately 200 patients with low levels of HDL...
Gene Therapy Technology Licensed In France.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
AVAX Technologies, Inc. announced that it has been granted an option to license the gene therapy technology developed by Professor Alain Fischer, MD, PhD, for treatment of the genetic disease,...
Animas, Diabetes Trust Fund Partner To Provide Insulin Pumps To Young Patients.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
Animas Corporation, manufacturer of the R1000 insulin pump, and the Diabetes Trust Fund have partnered to create The Diabetes Trust Fund Insulin Pump Plan. The program will make need-based...
Clinical Results Of Vaccine Trial Are Promising.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
Antex Biologics, Inc. announced results from the Phase IB clinical trial of Helivax, a vaccine intended to prevent and treat gastrointestinal infections and disease caused by Helicobacter pylori....
Treatment Boasts Money Back Guarantee.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
Berlex Laboratories, Inc., announced a money back guarantee program for patients using its topical acne medicine, Finevin (azelaic acid cream) 20%, for the treatment of mild-to-moderate...
Theratope Anticancer Vaccine Under FDA Review.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
Biomira Inc., (BIOM) and its collaborator, Merck KGaA, announced plans for a meeting with the U.S. Food and Drug Administration (FDA).
The purpose of the meeting is to review the Theratope...
Coronary Perfusion Imaging Agent Starts Phase II Trial.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
CV Therapeutics, Inc. announced that it has initiated a Phase II clinical trial of CVT-3146, a selective short-acting A2A adenosine receptor agonist.
CVT-3146 is being developed to selectively...
Lerdelimumab Evaluated In Combined Cataract And Glaucoma Surgery Trial.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
Cambridge Antibody Technology (CAT) announced the early results from a Phase II clinical trial using CAT-152 (lerdelimumab; human anti-TGFBeta(2) monoclonal antibody) in patients undergoing surgery...
Cell Genesys Appoints New Vice President of Research and Development.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
Cell Genesys, Inc. (CEGE) has announced that Peter K. Working, PhD, has joined the company in the new position of vice president, research and development.
Working, who served most recently as...
Peptide Drug Completes Promising Pilot Clinical Trial.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
Chrysalis Biotechnology, Inc. announced that it has completed analysis of a pilot Phase I/II clinical trial in diabetic ulcers for its drug Chrysalin.
This is the first clinical trial using...
3-D Molecular Structure Provides Structural Insight Into New Class of Protease Cancer Targets.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
Corvas International, Inc. reported that scientists and collaborators at the Max Planck Institute of Biochemistry in Martinsried, Germany, have solved the three-dimensional molecular structure of...
Preliminary Results Using Etanercept Are Positive.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
Immunex Corporation announced positive preliminary results from its first clinical study of Enbrel (etanercept) in psoriasis patients.
In this Phase II clinical study, 112 patients with...
Monoclonal Antibody Developed For Treatment/Prevention Of Infection.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
InterMune, Inc. (ITMN) announced that it has accepted a humanized monoclonal antibody targeted against the PcrV protein of the bacterium Pseudomonas aeruginosa.
The monoclonal form of the...
Medivir Signs Joint Venture Treatment Agreement with Chiron.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
Medivir and Chiron have signed a new collaboration agreement to work together on hepatitis C virus (HCV) infections treatments. Compound libraries from Medivir will be screened in Chiron's battery...
NeoTherapeutics Completes Site Selection For Phase II Trial.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
NeoTherapeutics, Inc. (NEOTW) announced that it has expanded its Neotrofin Phase II Parkinson disease trial to include four additional clinical locations.
New participants include Memorial...
NeoTherapeutics Expands Neotrofin Trials To Additional Sites.
September 19, 2001... 2001 SEP 19 - (NewsRx.com & NewsRx.net) --
NeoTherapeutics, Inc. (NEOT) announced that it has expanded its Neotrofin spinal cord injury trial to include Thomas Jefferson University Hospital, Pennsylvania, and Craig Rehabilitation Center,...