Biotech Week articles from July 2009

Biotech Week archives from July 2009

Studies from C.F. Yen et al provide new data on addiction medicine.
July 1, 2009... "The aim of the present study was to examine the discriminative effects of sociodemographic, individual, family, peers, and school life factors on Internet addiction in Taiwanese adolescents. A total of 8941 adolescents were recruited and...

Studies from J.A.R. Carr and co-researchers update current data on addiction medicine.
July 1, 2009... In this recent study, researchers in London, Canada conducted a study "To determine the incidence of concurrent substance misuse among individuals entering first-episode psychosis treatment, and examine whether patients with concurrent...

Reports summarize adenoma research from Osaka University, Medical Department.
July 1, 2009... "Tensin3 is a member of tensin family which is localized in focal adhesion. In our previous study, a high level of tensin3 mRNA expression was observed in the thyroid but not ill other tissues, thus, tensin3 gene was regarded as a novel...

Scientists at National Cheng-Kung University, Medical Department target adipose tissue.
July 1, 2009... "Adipocyte plays an important role in lipid regulation in mammals. Understanding of adipocyte differentiation becomes a key issue for the development of anti-obesity agent," investigators in Tainan, Taiwan report (see also Adipose Tissue). ...

New adolescence research from Ball State University outlined.(Report)
July 1, 2009... "This study takes a life-course approach to examine whether family, and religious characteristics influence individual-level delinquency, trajectories from early adolescence through young adulthood. Based oil data from the NLSY79, results...

Research from Michigan State University yields new findings on adolescence.
July 1, 2009... "The threat of victimization has been regarded as a central feature in both the development and the continuation of youth gangs. Although many studies find the need for protection to be a common reason youth join gangs, recent literature...

Study data from University of New Hampshire update understanding of adolescence.(Report)
July 1, 2009... According to recent research from the United States, "An important developmental task during adolescence is ego development. Millions of adolescents choose to initiate cigarette smoking at a young age as a result of transitional conflicts...

Research reports from Shanghai Jiao Tong University provide new insights into adult onset still disease.
July 1, 2009... In this recent study, researchers in Shanghai, People's Republic of China conducted a study "To describe the onset, clinical features, prognostic factors, and treatment of adult-onset Still's disease (AOSD) in cases from China. Sixty-one...

Studies in the area of adverse drug reactions reported from S. Wangweigand and co-researchers.(Clinical report)
July 1, 2009... "Ramelteon is an MT1/MT2 melatonin receptor agonist indicated for the treatment of insomnia characterized by difficulty with sleep onset. In previous clinical studies, ramelteon reduced latency to persistent sleep (LPS) in subjects with chronic...

New aggression study results from R. Perrone et al described.(Report)
July 1, 2009... "Brachyhypopomus pinnicaudatus (pulse-type weakly electric fish) is a gregarious species that displays reproductive behavior and agonistic encounters between males only during the breeding season. During social interactions, in addition to its...

Data on aging detailed by N. Alipanah and co-authors.
July 1, 2009... According to recent research published in the Journal of Nutrition Health & Aging, "Walking speed is an important measure of physical performance that is predictive of disability and mortality. The relationship of dietary factors to changes in...

Findings from Monash University in aging reported.
July 1, 2009... According to recent research from Parkville, Australia, "We characterized spontaneous electrical activity in the aging guinea pig prostate. Membrane potential recordings were made using conventional single microelectrode recording techniques."...

New aging research from University of Medicine and Dentistry of New Jersey discussed.
July 1, 2009... According to a study from the United States, "Potassium channels are key regulators of neuronal excitability. Here we show that oxidation of the K+ channel KVS-1 during aging causes sensory function loss in Caenorhabditis elegans and that...

New behavior research has been reported by scientists at Georgia State University.
July 1, 2009... "Previous research on police officer shoot decisions has focused on the influence of situational factors that lead to shooting error. Focusing instead on the ''shooter,'' the present study examined whether WM capacity influenced participant...

Reports from C.R. Burtner and co-researchers add new data to research in aging.
July 1, 2009... "The molecular mechanisms that cause organismal aging are a topic of intense scrutiny and debate. Dietary restriction extends the life span of many organisms, including yeast, and efforts are underway to understand the biochemical and genetic...

Reports from University of Montpellier highlight recent research in aging.
July 1, 2009... According to recent research published in the journal Aging & Mental Health, "The present study was prompted by the lack of agreement on how coping changes with age. We postulate that the effect of age on coping is mediated by coping resources,...

Research from Hallym University, Medical Department in the area of aging published.
July 1, 2009... According to recent research published in the journal Cellular and Molecular Neurobiology, "Oxidative stress is one of predisposing factors to age-related neurodegeneration in the brain. In particular, thiol-containing groups are susceptible to...

Research on aging discussed by scientists at University of Wisconsin.
July 1, 2009... "Age-related changes in tongue function may contribute to dysphagia in elderly people. The authors' purpose was to investigate whether aged rats that have undergone tongue exercise would manifest increased protrusive tongue forces and increased...

Studies from Ben-Gurion University in the area of aging published.
July 1, 2009... According to recent research published in the Journal of Nutrition Health & Aging, "To examine the association between dietary factors to daily activity energy expenditure (DAEE) and mortality among older adults. A sub-study of Health, Aging,...

Study data from Dalhousie University update knowledge of aging.
July 1, 2009... According to recent research published in the Journal of Nutrition Health & Aging, "Smoking has adverse effects on a variety of organ systems but little is known about the relationship between smoking and frailty. We aimed to investigate...

New alcoholism research from Seoul National University discussed.(Report)
July 1, 2009... According to recent research published in the Journal of Pharmacological Sciences, "The generally accepted hypothesis for the pathogenesis of alcoholic liver disease (ALD) is the two-hit model, which proposes that fat accumulation in the liver...

University of Bristol reports research in alcoholism.(Report)
July 1, 2009... According to recent research from Bristol, the United Kingdom, "We recently demonstrated that alcohol elicits a difference between men and women in perceptual threshold for facial expressions of sadness. However, this study did not include a...

Investigators at University of Tokushima target allergies.
July 1, 2009... According to recent research published in the Journal of Pharmacological Sciences, "Kujin, the dried root of Sophorae flavescensis, has been used in Chinese folklore medicine against allergy. Evaluation of its anti-allergic potential as welt as...

New allergies research has been reported by scientists at Southampton General Hospital.
July 1, 2009... "Leukotrienes (LTs) and prostanoids are potent pro-inflammatory and vasoactive lipid mediators implicated in airway disease, but their cellular sources in the nasal airway in naturally occurring allergic rhinitis (AR) are unclear. To quantify...

Recent findings in allergies described by K. Ahn and colleagues.
July 1, 2009... According to recent research from the United States, "IgE-mediated allergic reactions to pistachio appear to be occurring more frequently; however, little is known about its allergenic proteins. We attempted to identify pistachio allergens and...

Studies from University of Florence further understanding of allergies.
July 1, 2009... "Allergic reactions to beta-lactams are a frequent cause of adverse drug reactions; the diagnosis is based on history, clinical examination, skin testing (prick and intradermal) and demonstration of serum-specific IgE antibodies (Abs). We...

Studies from Seoul National University yield new information about allergy medicine.
July 1, 2009... "Evidence for beneficial effects of squalene on ultraviolet (UV)-induced photoaging of the skin is lacking. To investigate whether squalene supplementation improves signs and molecular markers of photoaging in human skin in vivo," researchers...

Findings from R. Ramirezlorca and co-authors broaden understanding of Alzheimer disease.
July 1, 2009... "The genetic basis of Alzheimer's disease (AD) is being analyzed in multiple whole genome association studies (WGAS). The GAB2 gene has been proposed as a modifying factor of APOE epsilon 4 allele in a recent case-control WGAS conducted in the...

New Alzheimer disease study findings have been reported by C. Sampaio and co-researchers.
July 1, 2009... According to recent research published in the Journal of Nutrition Health & Aging, "Biomarkers are key for the different phases of drug development in Alzheimer Disease and in other fields. Traditionally the process of biomarker qualification...

Research from University of Texas reveals new findings on Alzheimer disease.
July 1, 2009... According to a study from the United States, "The pathomechanism of Alzheimer's disease (AD) is multifactorial although the most popular hypotheses are centered on the effects of the misfolded, aggregated protein, amyloid beta (A beta) and on...

Researchers at University of Dublin, Trinity College have published new data on Alzheimer disease.(Report)
July 1, 2009... According to recent research from Dublin, Ireland, "In the earliest clinical stages of Alzheimer's Disease (AD), when symptoms are mild, clinical diagnosis will still be difficult. AD related molecular mechanisms precede symptoms." ...

Researchers from Dong-A University provide details of new studies and findings in the area of amyloidosis.
July 1, 2009... "Amyloidosis is characterized by the extracellular deposition of amyloid protein in various organs. Gastrointestinal involvement in amyloidosis is common, but a diagnosis of amyloidosis is often delayed," scientists writing in the journal...

Data from S. Saxena et al provide new insights into amyotrophic lateral sclerosis.
July 1, 2009... According to recent research from Basel, Switzerland, "The mechanisms underlying disease manifestations in neurodegeneration remain unclear, but their understanding is critical to devising effective therapies. We carry out a longitudinal...

Research data from Northwestern University update understanding of amyotrophic lateral sclerosis.
July 1, 2009... According to a study from the United States, "The alanine to valine mutation at codon 4 (A4V) of SOD1 causes a rapidly progressive dominant form of amyotrophic lateral sclerosis (ALS) with exclusively lower motor neuron disease and is...

Research from S. Tartari and colleagues has provided new data on amyotrophic lateral sclerosis.
July 1, 2009... "Motor neuron degeneration in amyotrophic lateral sclerosis involves oxidative damage. Glutathione (GSH) is critical as an antioxidant and a redox modulator," scientists writing in the Febs Journal report (see also Amyotrophic Lateral...

Research from University of Maryland provide new insights into analgesics.
July 1, 2009... "Chronic morphine administration may alter the expression of hundreds to thousands of genes. However, only a subset of these genes is likely involved in analgesic tolerance," scientists in the United States report (see also Analgesics). ...

Findings in anaphylactic shock reported from National Institutes of Health.
July 1, 2009... According to recent research from the United States, "To report a case of probable anaphylaxis due to anakinra in a patient with rheumatoid arthritis and multiple drug allergies. SUMMARY: A 46-year-old Indian female with rheumatoid arthritis...

George Washington University reports research in anatomy.(Report)
July 1, 2009... According to a study from the United States, "In a recent study Diogo & Abdala [(2007) J Morphol 268, 504-517] reported the results of the first part of a research project on the comparative anatomy, homologies and evolution of the pectoral...

New anatomy study results from I. Derakhshan et al described.
July 1, 2009... "Although the relationship of handedness to the ability to talk has been known to the ancients (Psalm 137, for example) the exact knowledge of anatomical underpinnings of this relationship at the public level is a new understanding. This...

Studies from Marshall University add new findings in the area of anatomy.(Report)
July 1, 2009... According to recent research from the United States, "Animal models have contributed greatly to the study of voice, permitting the examination of laryngeal biology and the testing of surgical, medical, and behavioral interventions. Various...

New findings in anesthesia described from Roosevelt Hospital.
July 1, 2009... According to recent research published in the journal Muscle & Nerve, "Until now, there have been no reports on eliciting the blink reflex (BR) during anesthesia at a depth compatible with surgery. We introduce a novel method for eliciting the...

Research from University of Toronto in the area of anesthesia published.(Report)
July 1, 2009... According to recent research published in the journal Regional Anesthesia and Pain Medicine, "Epidural anesthesia is a technically challenging regional anesthetic technique that can be difficult to teach to novices. Epidural simulators are now...

Studies from E. Duggan et al have provided new data on anesthesia.(Report)
July 1, 2009... "The aim of this study was to determine the minimum effective anesthetic volume required to produce an effective supraclavicular block for surgical anesthesia using an ultrasound (US)-guided technique. Twenty-one adults undergoing elective...

Wake Forest University, Medical Department details research in anesthesia.
July 1, 2009... According to recent research from the United States, "For knee surgery, obturator nerve block (ONB) has been shown to enhance postoperative analgesia provided by femoral block. Current techniques for obturator block use surface landmarks or...

Research from Osaka University, Medical Department in the area of angiography published.(Report)
July 1, 2009... According to recent research from Suita, Japan, "The purpose of this study was to evaluate the usefulness of a tool that we developed to simulate performance of visceral angiography to train beginners in the field of splanchnic angiography....

Research on angiography reported by H. Kramer et al.
July 1, 2009... According to a study from Munich, Germany, "Imaging of the arteries of the lower extremity is most often performed in patients who have known or suspected peripheral artery occlusive disease." "Due to the recent advances in imaging...

Studies from M. Yamamoto and co-authors have provided new information about angiography.
July 1, 2009... "The purpose of this research is to develop a new method of digital subtraction angiography (DSA) that can be applied to real time with reducing motion artifacts caused by heart movement and respiration. To create the mask image for DSA, the...

Data from University of Copenhagen provide new insights into angiology.
July 1, 2009... "The purpose of this investigation was to determine the contribution of muscle O-2 consumption (m(V) over dot(O2)) to pulmonary O-2 uptake (p(V) over dot(O2)) during both low-intensity (LI) and high-intensity (HI) knee-extension exercise, and...

New angiology findings from M.A. Mateev and co-authors described.
July 1, 2009... In this recent study, researchers in Bishkek, Kyrgyzstan conducted a study "To overcome the donor-site morbidity associated with radial forearm flaps, many modifications of this technique have been reported, including the development of the...

New angiology research reported from Shanghai Jiao Tong University.
July 1, 2009... "In the present study, we compared the elastin and collagen content of thoracic aortic medial and adventitial layers from Wistar-kyoto (WKY) and spontaneously hypertensive rats (SHR). In addition, the effects of losartan, an angiotensin II...

New angiology study findings recently were reported by researchers at Semmelweis University.(Report)
July 1, 2009... "Carotid stenting is a minimally invasive treatment for extracranial carotid artery stenosis. Stent design may affect technical success and complications in a certain subgroup of patients," scientists in Budapest, Hungary report (see also...

Recent findings from Showa University highlight research in angiology.(Report)
July 1, 2009... "The objective of this Study was to compare intracellular Calcium concentration ([Ca2+](i)) and contractile responses in isolated rat middle cerebral artery (MCA) with those in basilar artery (BA) employing real-time confocal laser microscopy....

Studies from Royal London Hospital add new findings in the area of angiology.(Report)
July 1, 2009... "The purpose of this study was to examine the immediate and midterm outcomes of percutaneous endovascular repair of thoracic and abdominal aortic pathology. Between December 2003 and June 2005, 21 patients (mean age: 60.4 +/- A 17.1 years; 15...

Study results from Q.V. Vu and colleagues in the area of angiology published.(Clinical report)
July 1, 2009... According to a study from Hanoi, Vietnam, "The supraclavicular flap is an excellent flap that has been used widely, but its vascular reliability remains unclear. In this article, the authors report the results of their anatomical studies on 40...

Reports summarize angioplasty research from Baskent University.(Report)
July 1, 2009... "The aim of this study was to report our experience in endovascular treatment of total aortoiliac occlusion. Five patients who underwent endovascular recanalization procedures including manual aspiration thrombectomy, balloon angioplasty, and...

Findings from Chinese University of Hong Kong in angiotensins reported.
July 1, 2009... According to recent research from Hong Kong, People's Republic of China, "Angiotensin II has been shown to play a role in the pathogenesis of acute pancreatitis (AP). The present investigation aimed at elucidating redox-sensitive mechanistic...

New angiotensins research from D.J. Campbell and colleagues discussed.
July 1, 2009... "There is continuing uncertainty about the tissue compartments where angiotensin and bradykinin peptide formation occurs. Mice with angiotensin-converting enzyme (ACE) expression targeted to the cardiomyocyte membrane provide a unique...

New findings reported from P. Singh and co-authors describe advances in angiotensins.
July 1, 2009... According to recent research from the United States, "Singh P, Deng A, Blantz RC, Thomson SC. Unexpected effect of angiotensin AT(1) receptor blockade on tubuloglomerular feedback in early subtotal nephrectomy." "Am J Physiol Renal Physiol...

Reports summarize angiotensins research from New York Medical College, Medical College.(Report)
July 1, 2009... According to a study from the United States, "Jin Y, Wang Y, Wang Z, Lin D, Wang W. Inhibition of angiotensin type 1 receptor impairs renal ability of K conservation in response to K restriction. Am J Physiol Renal Physiol 296: F1179-F1184,...

Research data from J. Yatabe and colleagues update understanding of angiotensins.(Report)
July 1, 2009... According to recent research published in the American Journal of Physiology - Renal Physiology, "Yatabe J, Sanada H, Yatabe MS, Hashimoto S, Yoneda M, Felder RA, Jose PA, Watanabe T. Angiotensin II type 1 receptor blocker attenuates the...

Research from Kyoto University provides new data about angiotensins.
July 1, 2009... According to a study from Kyoto, Japan, "Novokinin (Arg-Pro-Leu-Lys-Pro-Trp) is a vasorelaxing and hypotensive peptide acting through the angiotensin AT(2) receptor. Centrally administrated novokinin (30 nmol/mouse) inhibited the...

Research from Washington University, Medical Department has provided new information about angiotensins.
July 1, 2009... "Residues that mediate helix-helix interactions within the seven transmembranes (TM) of G protein-coupled receptors are important for receptor biogenesis and the receptor switch mechanism. By contrast, the residues directly contacting the lipid...

Research from Y. Okunuki et al has provided new information about angiotensins.(Report)
July 1, 2009... According to a study from Tokyo, Japan, "Angiotensin II type 1 receptor (AT1-R) blockers are used widely for the treatment of patients with hypertension. Recent reports have suggested that AT1-R also plays a key role in various inflammatory...

Researchers at Mukogawa Women's University target angiotensins.(Report)
July 1, 2009... According to recent research published in the Journal of Pharmacological Sciences, "We have previously reported that peroxynitrite is involved in dysfunction of nitric oxide (NO)-mediated vasorelaxation in SHR/NDmcr-cp rats (SHR-cp), which...

Researchers from National Defense Medical College, Medical College describe findings in angiotensins.(Report)
July 1, 2009... "Angiotensin (Ang) II plays an important role in fibrogenesis in various organs, including the lung. The aim of this study is to elucidate (i) the effects of Ang II on the expression of cytokines, growth factors or matrix proteins in normal...

Studies from Uludag University in the area of angiotensins described.
July 1, 2009... "1. The aims of the present study were to determine the cardiovascular effects of arachidonic acid (AA) and to investigate the peripheral mechanisms mediating these effects in haemorrhage-induced hypotensive rats. 2. Acute haemorrhage was...

Study data from Johns Hopkins University update knowledge of angiotensins.
July 1, 2009... According to recent research published in the Journal of Urology, "Angiotensin II is a known mediator of smooth muscle vasoconstriction and fibrosis. It up-regulates thrombospondin-1, a major activator of latent transforming growth...

Study data from Z.A. Radi and co-authors update knowledge of angiotensins.
July 1, 2009... "Hypertensive mice expressing the human renin (REN) and angiotensinogen (AGT) genes are used as a model for human hypertension. The aim of the present study was to investigate the cellular expression and distribution of inducible nitric oxide...

University of Sherbrooke, Medical Department details research in angiotensins.
July 1, 2009... According to recent research published in the Journal of Biological Chemistry, "The octapeptide hormone angiotensin II (AngII) exerts a wide variety of cardiovascular effects through the activation of the angiotensin II type-1 (AT1) receptor,...

New ankylosing spondylitis study findings have been reported by scientists at Vrije University Amsterdam.
July 1, 2009... According to recent research from Netherlands, "Cardiovascular mortality is increased in ankylosing spondylitis (AS), and inflammation plays an important role. Inflammation deteriorates the lipid profile and alters high-density lipoprotein...

Researchers from Hanyang University describe findings in ankylosing spondylitis.
July 1, 2009... "IL23R polymorphisms have been shown to have a significant association with ankylosing spondylitis (AS). To date, these Studies have been restricted to Caucasian patients with AS," researchers in Seoul, South Korea report (see also Ankylosing...

Studies from Ruhr University in the area of ankylosing spondylitis described.
July 1, 2009... In this recent study, researchers in Herne, Germany conducted a study "To describe the natural Course of radiographic progression and to differentiate rates of progression in patients with ankylosing spondylitis (AS). Overall, 146 patients with...

Studies from University of Paris provide new data on ankylosing spondylitis.(Report)
July 1, 2009... According to a study from Clamart, France, "A minority of patients with ankylosing spondylitis (AS) fail to respond to infliximab treatment. This study compared the circulating infliximab concentration and the presence of clinical symptoms in...

Study data from J.A. Singh and colleagues update understanding of ankylosing spondylitis.
July 1, 2009... In this recently published article, scientists in the United States conducted a study "To Study physical function and health-related quality of life (HRQOL) in US veterans with spondyloarthritis (SpA). In a postal survey of 70,334 eligible...

Recent studies by S.S. Yeh and co-authors add new data to anorexia-cachexia syndrome findings.(Clinical report)
July 1, 2009... According to recent research from the United States, "The aim of this review is to assess the efficacy and safety of megestrol acetate (MA) in geriatric cachexia. The paper presented here reviews a previously published study of MA use in 69...

Recent findings in anterior uveitis described by S. Munozfernandez and colleagues.(Clinical report)
July 1, 2009... According to recent research published in the journal Eye, " To evaluate the efficacy of methotrexate (MTX) in preventing the recurrence of acute anterior uveitis (AAU). This prospective, open, longitudinal study included patients from June...

New anti-infectives study findings have been reported by scientists at University of Paris.
July 1, 2009... "The characterization of AmpC-type beta-lactamases was performed in a collection of 32 clinical Pseudomonas aeruginosa isolates with intermediate susceptibility or resistance to imipenem and ceftazidime. Twenty-one out of those 32 isolates...

New findings from A.S. Millan and co-authors describe advances in anti-infectives.
July 1, 2009... According to recent research from Paris, France, "Three Enterococcus faecium strains isolated successively from the same patient, vancomycin-resistant strain BM4659, vancomycin-dependent strain BM4660, and vancomycin-revertant strain BM4661,...

Reports from J. Weers et al highlight recent research in anti-infectives.(Report)
July 1, 2009... According to a study from the United States, "The purpose of this study was to investigate the inhalation of a liposomal formulation of amikacin in healthy male volunteers in terms of pulmonary deposition, clearance, and safety following...

Reports outline anti-infectives study results from G. Weiss et al.
July 1, 2009... "This prospective, randomized, open, international, multicenter study of adults with complicated intra-abdominal infections (clAI) compared the efficacy and safety of sequential intravenous (i.v.) to oral (p.o.) moxifloxacin 400 mg once daily,...

Study results from F. Depardieu and colleagues in the area of anti-infectives published.
July 1, 2009... According to a study from Paris, France, "We studied the clinical isolates Enterococcus faecium NEF1, resistant to high levels of vancomycin (MIC, 512 mu g/ml) and teicoplanin (MIC, 64 mu g/ml); Enterococcus faecium BM4653 and BM4656 and...

Studies from E. Pereamilla et al have provided new data on antibiotherapy.
July 1, 2009... According to recent research published in the journal BMC Public Health, "Mortality from invasive meningococcal disease (IMD) has remained stable over the last thirty years and it is unclear whether pre-hospital antibiotherapy actually produces...

Data on antibiotics discussed by G. Suarez and colleagues.
July 1, 2009... According to recent research from Neuchatel, Switzerland, "A multiplexed immunoassay-based antibiotic sensing device integrated in a lab-on-a-chip format is described. The approach is multidisciplinary and involves the convergent development of...

Data on antibiotics reported by researchers at University of Minnesota.
July 1, 2009... According to a study from the United States, "Simocyclinone D8 (SD8) exhibits antibiotic activity against gram-positive bacteria but not against gram-negative bacteria. The molecular basis of the cytotoxicity of SD8 is not fully understood,...