Biotech Week articles from February 2004

Biotech Week archives from February 2004

New drug improves outcomes when added to existing therapy for AD.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- The drug memantine lessens the decline in cognition and activities of daily living for patients with moderate to severe Alzheimer disease (AD) who are also receiving donepezil (another drug used to...

Successful, rapid protein crystallization possible with new technique.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- An innovative method that allows increased success and speed of protein crystallization - a crucial step in the laborious, often unsuccessful process to determine the 3-dimensional structure unique to...

U.S. patent granted for treatment of human papillomavirus infections.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Advanced Viral Research Corp. (ADVR) announced that it has been awarded U.S. Patent Number 6.670,118 entitled "Method for Treating Papillomavirus Infections." The patent describes the use of AVR118...

Phase III study of Actimmune published in leading journal.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- InterMune, Inc., (ITMN) announced the publication in the New England Journal of Medicine of previously presented results of the company's initial randomized, double-blind, placebo-controlled, phase III...

NCX 4016 successfully achieves primary efficacy endpoint in phase II study.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- NicOx, SA, (NICOX) announced that NCX 4016 reached its primary efficacy endpoint in a phase IIa study in patients with symptomatic peripheral arterial obstructive disease (PAOD). NCX 4016 is a...

Drop in hormone therapy use shows doctors heed research findings.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- The dramatic drop in prescriptions for postmenopausal hormone replacement therapy after the risks of long-term estrogen/progestin use were announced suggests that physicians respond more readily to new...

Health insurance lobby group releases forecast of states' issue in 2004.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- At a January 14, 2004, press briefing, the American Association of Health Plans-Health Insurance Association of America (AAHP-HIAA) released its State Forecast 2004 report outlining issues that will be...

Results of CHF drug trials reported.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Results from a variety of CHF drug trials have been reported. "There is now evidence for the efficacy and safety of a variety of neurohormonal modulators in chronic heart failure (CHF),"...

New board members named at pharmaceutical company.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- ARYx Therapeutics, Inc., announced the election of Paul Goddard, PhD, and Lars Ekman, MD, PhD, as members of the company's board of directors. Goddard was also appointed chairman of the board. ...

Device firm provides preliminary outlook on fourth quarter results.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- ATS Medical, Inc., (ATSI) reported that fourth quarter revenue is expected to increase more than 50% to approximately $5.6 million, as compared to sales of $3.7 million for the quarter ended December...

Inhibition of SARS coronavirus with Neugene antisense drugs reported.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- AVI BioPharma, Inc., (AVII) presented confirmatory positive results on the inhibition of the SARS coronavirus using its Neugene antisense drugs. Michael Buchmeier, PhD, of The Scripps Research...

A 10-degree reverse Trendelenburg position can reduce pressure during craniotomy.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- During craniotomy, a 10-degree reverse Trendelenburg position rapidly reduces subdural pressure and dural tension reducing cerebral perfusion pressure (CPP). "Recently we studied the effect of...

Myriad Genetics agreement to include pharmacogenetics.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Myriad Genetics, Inc., (MYGN), and Abbott Laboratories, Inc., (ABT) have expanded their strategic alliance to include a broad new pharmacogenetics program. The research collaboration will focus on...

Malignant stem cells express high levels of FGFR-3.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Leukemic stem cells express heightened levels of FGFR-3. Scientists in the Czech Republic had previously found that "expression of myeloma-associated (proto) oncogene fibroblast growth factor...

Milestone achieved as Allergan advances glaucoma drug candidate.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Acadia Pharmaceuticals announced that it has achieved a milestone in its collaboration agreement with Allergan (AGN) to discover, develop, and commercialize selective muscarinic drugs for the treatment...

$32M raised to advance multiple cardiovascular device opportunities.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Accelerated Technologies, Inc., (ATI), a New York-based partnership model for the creation and acceleration of cardiovascular devices into the market, announced that it received $32 million in funding...

Agreement signed with Wyeth for OTC product using OraDisc technology.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Access Pharmaceuticals, Inc., (AKC) announced that it has executed a licensing agreement with Wyeth Consumer Healthcare, a division of Wyeth (WYE), granting Wyeth the North American rights to develop...

Abnormal scotopic threshold response linked to stationary night blindness.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Abnormalities of the scotopic threshold response correlate with gene mutation in X-linked retinoschisis and congenital stationary night blindness. According to a study from England, "Scotopic...

Milestone payment of $3M received from deal with GlaxoSmithKline.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Advancis Pharmaceutical Corporation (AVNC) announced the achievement of the first milestone in a collaboration with GlaxoSmithKline (GSK). As a result, Advancis received a payment of $3.0 million...

Chief financial officer appointed at drug delivery development firm.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Aesgen, Inc., announced the appointment of David J. Cammarata as its chief financial officer (CFO). Before joining Aesgen, Inc., Cammarata was CFO at Lavipharm Corporation and CFO, vice president...

Mayo Clinic official joins board of pharmaceutical company.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Aesgen, Inc., a specialty pharmaceutical company, announced the appointment of Steven Stenhaug to its board of directors. Stenhaug's 20-year career includes extensive experience in finance,...

Hepatitis C glycoprotein expression leads to cryptic intron excision.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Expression of unmodified hepatitis C virus envelope glycoprotein-coding sequences leads to cryptic intron excision and cell surface expression of E1/E2 heterodimers comprising full-length and partially...

Rats exposed to morphine before birth exhibit normal maternal behaviors.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Rats exposed to morphine before birth exhibit normal maternal behaviors. According to a study from the United States, "previous studies have demonstrated that chronic morphine treatment of pregnant...

Women with systemic lupus erythematosus are at risk for losing bone density.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Women with systemic lupus erythematosus are at risk for losing bone density. According to recent research from Bulgaria, "the aim of this study was to analyze the heterogeneity of bone mineral...

Survey shows healthcare a top issue in 2004 election.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- As the 2004 election cycle begins in the U.S., voters expect candidates to address healthcare issues, according to a new national survey conducted by Public Opinion Strategies and Greenberg Quinlan...

Report: Medicare ER bills show worrisome variations in hospital coding.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- More than a year after implementation of the Medicare outpatient prospective payment system (OPPS), there are unexpected variances in the assignment of evaluation and management (E&M) codes on emergency...

Report gives failing grades to state of Missouri.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- In a national report released by the American Lung Association, the state of Missouri received mostly failing grades for its efforts to fight the harmful effects of tobacco use, demonstrating little...

Insurance company extends consumer-centric products with HSAs.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- American Medical Security Group, Inc., (AMZ, AMS) announced that the independent agents marketing its products to individuals are now offering Health Savings Accounts (HSA) coupled with the company's...

Group adopts new policies, some addressing women's issues.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- The American Public Health Association (APHA) recently adopted 27 policies addressing a broad range of issues in public health from emergency contraception and the public health nursing shortage to...

Genome Therapeutics retains certain rights to bone diseases' research program.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Genome Therapeutics Corp. (GENE) and Amgen, Inc., have concluded their research collaboration focused on discovering and developing therapeutics for bone diseases. Announced in January of 2003, the...

Swiss regulatory application for Symlin withdrawn.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Amylin Pharmaceuticals, Inc., (AMLN) announced receipt of correspondence from the Swiss Agency for Therapeutic Products (Swissmedic) indicating that Symlin could not be approved for marketing in...

Drug makers sign deal to develop combined diabetes product from Actos, Fortamet.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Andrx Corporation of Fort Lauderdale, Florida, (ADRX) and Takeda Chemical Industries, Ltd., of Osaka, Japan, have entered into an agreement to develop and market a combination product consisting of...

FDA grants tentative approval for generic Ortho Tri-Cyclen.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Andrx Corporation (ADRX) announced that the U.S. Food and Drug Administration (FDA) has tentatively approved the company's Abbreviated New Drug Application (ANDA) for Ortho Tri-Cyclen...

Longer interferon regimens might clear hepatitis D virus.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Longer interferon regimens might clear hepatitis D virus. According to published research from Turkey, "chronic hepatitis B virus (HBV) infection is a common infectious disease in the world. Two...

Agreement signed with ProSkelia for new gel products.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Antares Pharma, Inc., (ANTR) announced that it had signed a development and licensing option agreement with ProSkelia, SAS, a company with headquarters near Paris, France, for the development and future...

Argentina IDUs have high HIV rate.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Drug injecters in Argentina have a high rate of HIV infection. Researchers there conducted a study "to compile published data and to describe the prevalences of human immunodeficiency virus (HIV)...

Vaccines based on Plasmodium vivax Sal I strains show promise.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Malaria vaccines based on Plasmodium vivax Sal I strains show promise in animal models. "We have previously demonstrated that mouse antisera against yeast-produced recombinant forms of the ookinete...

Published study results show BIS monitoring reduces intraoperative awareness.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Aspect Medical Systems (ASPM) announced that results from a Swedish study documenting a 77% reduction in the incidence of intraoperative awareness with recall when BIS monitoring was used was published...

Apolipoprotein-E-deficient mice resistant to atherosclerosis.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Mice deficient in apolipoprotein E but not LDL receptors are resistant to accelerated atherosclerosis associated with obesity. "The aims of this study were to determine whether mice induced to...

Iressa phase II trial data published.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- New data published in the Journal of Clinical Oncology (JCO) highlight the first phase II clinical trial of Iressa (gefitinib) Tablets in patients with recurrent glioblastoma. Glioblastoma is the...

Trade publication recognizes pharmaceutical company's product pipleine.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- AstraZeneca was named to have the best product pipeline in the pharmaceutical industry by R&D Directions, a pharmaceutical trade publication. The editors of R&D Directions have identified 10...

Atrigel formulation advances into additional human clinical testing.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Atrix Laboratories, Inc., (ATRX) announced that Atrix's partner, Pfizer Inc, has completed the initial phase of clinical testing of CP-533,536 formulated in the Atrigel sustained-release drug delivery...

Atrisone completes pivotal phase III studies.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Atrix Laboratories, Inc., (ATRX) announced that the company's proprietary acne drug, Atrisone (5% topical dapsone gel) has successfully completed two pivotal phase III clinical efficacy studies. ...

Specialist clinic service for HIV+ mineworkers helps prevent TB.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- A novel clinic helps prevent tuberculosis and other infections in HIV+ mineworkers. "Occupational settings offer an ideal opportunity to provide preventive health services for HIV-infected workers,"...

Bone disease biotech company closes $1.6M financing.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Auxeris Therapeutics, Inc., a biopharmaceutical company focused on the development and commercialization of medicines to treat a broad range of bone diseases, announced the completion of a $1.6M...

Alliance to develop, commercialize influenza vaccines.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Aventis (AVE) and Crucell N.V. (CRXL) announced that they have entered into a strategic agreement to further develop and commercialize novel influenza vaccine products based on Crucell's proprietary...

CsA derivatives show promise as antiretroviral agents.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- A series of novel CsA-derived agents strongly inhibit HIV activity with limited immunomodulatory effects. In a study conducted by M. Evers and colleagues at Aventis Pharma S.A. in Vitry-sur-Seine,...

Blood clot risk not treated preventively, study finds.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- In a nationwide study of hospitalized patients, researchers at Duke University Medical Center and Brigham and Women's Hospital found that people at risk for developing deep vein thrombosis (DVT) - a...

Clinical trials firm names Bennett as director.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Averion, Inc., announced the appointment of Randy Bennett as director of late phase studies and clinical monitoring. In this role, Bennett will direct the coordination and execution of late phase...

$50 million private placement of common stock and warrants issued.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Axonyx, Inc., (AXYX) announced that the company has entered into definitive agreements with new and existing institutional investors relating to a private placement of $50 million of securities through...

Rise in homocysteine level rapidly increases arterial stiffness.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- A rise in homocysteine levels causes a rapid increase in arterial stiffness. "Homocysteine appears to be causally related to cardiovascular disease and shown to induce endothelial dysfunction,"...

Health contracts guide older adults into regular exercise.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Sedentary older adults exercise more by entering into a health contract that combines a fitness regimen with motivation, social support and memory recall techniques, says a Ball State University...

Tentative approvals granted for Modafinil, Topiramate.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Barr Pharmaceuticals, Inc., (BRL) announced that its wholly owned subsidiary, Barr Laboratories, Inc., has received tentative approvals from the U.S. Food and Drug Administration (FDA) for its generic...

Inhaled pharmaceuticals maker changes name to Ventaira.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- BattellePharma announced that it has changed its name to Ventaira Pharmaceuticals, Inc., to reflect the company's transition to a specialty pharma company focusing on inhaled pharmaceuticals. ...

Flavonoids inhibit Syk activity and promote degranulation of human mast cells.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Flavonoids inhibit Syk activity and promote degranulation of human mast cells. According to a study from Japan, "To investigate the effect of flavonoids on the activation of p72[superscript]syk...

Deoxyribonuclease II cripples nonviral transfection.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Deoxyribonuclease II cripples nonviral transfection. According to recent research from the United States, "DNA delivered in nonviral vectors or as naked DNA must overcome a number of extracellular...

Idarubicin unlikely to be used for treating primary CNS tumors.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Study results indicate that it is unlikely that Idarubicin (IDA), daunomycin, or other related anthracyclines will be useful for treating primary CNS tumors," researchers say. "IDA, the 4-demethoxy...

New highly scalable GenomeLab system launched.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Beckman Coulter, Inc., (BEC) began shipping its new GenomeLab SNPstream Genotyping System. Capable of performing 4,600 to more than 800,000 genotypes per day, SNPstream offers scalability unmatched...

Pharmaceutical company announces almost all redeemable warrants exercised.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Bentley Pharmaceuticals, Inc., (BNT) announced that almost all of the company's outstanding Class B redeemable warrants were exercised prior to expiration on December 31, 2003. Approximately...

Report: Market research critical to blockbuster launches.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- In an increasingly competitive market, pharmaceutical companies invest more and more in market research to improve product positioning, according to a study by pharmaceutical research firm, Best...

Lab company reports record operating results for fourth quarter.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Bio-Reference Laboratories, Inc., (BRLI) released its fourth quarter, fiscal year 2003 earnings for the 3 months ending October 31, 2003. For the quarter, the company posted record pre-tax net...

Pharmaceutical companies establish alliance to develop periodontal product.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- BioMimetic Pharmaceuticals, Inc., (BMPI) announced that it has established a worldwide strategic alliance with Luitpold Pharmaceuticals, Inc., a subsidiary of Sankyo Co., Ltd., for research,...

Subcontract given to develop anthrax vaccines using nanotechnology.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- BioSante Pharmaceuticals, Inc., (BPA) announced that it has been awarded a subcontract valued at $658,207 for the development of anthrax vaccines for delivery via alternative routes of administration....

Nanotechnology portfolio expands with U.S. patent.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Biophan Technologies, Inc., (BIPH), an innovator, developer, and marketer of advanced biomedical technology, announced that its licensor for nanomagnetic particle technologies has been issued a U.S....

Hemopure regulatory status updated following FDA meeting.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Biopure Corporation (BPUR) reported that, on January 6, 2004, the company and the U.S. Food and Drug Administration (FDA) met at Biopure's request to discuss its reply to the FDA complete response...

Ethnicity may affect allergies in children with asthma.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Puerto Rican and African American children with asthma may be at risk for multiple indoor and outdoor allergies, says a new study. The study found that Puerto Rican children with asthma were up to...

Telomerase is a major regulator of leukemia cell growth.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Telomerase is a major regulator of leukemia cell growth. According to recent research published in the journal Leukemia, "telomeres play an important role in the proliferation and senescence of...

HIV genital tract shedding linked to plasma viremia.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- HIV genital tract shedding is correlated with plasma viremia. In a recent study, researchers "examined 30 HIV-infected women in Manila to assess the relationship between cervicovaginal and plasma...

Haase leaves x-ray analysis company.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Bruker BioSciences Corporation (BRKR) announced that Martin Haase will leave the company at the end of April 2004 to pursue other interests. Haase presently serves as senior VP of Bruker BioSciences...

FDA 510k clearance granted for dual lumen extended length catheter.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- CHF Solutions has received 510(k) marketing clearance from the U.S. Food and Drug Administration for a dual lumen extended length catheter (dELC) for use with the company's System 100 Fluid Removal...

Adoptive immunity fosters gene expression after cell transfection.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Adoptive immunity fosters gene expression after cell transfection. "Like cellular transplantation, gene therapy is often limited by immune rejection of the newly expressed antigen. In a model of...

Medication reduces angina attacks, increases exercise capacity for patients.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Taken with other anti-anginal medications, the drug ranolazine reduces the frequency of angina and increases exercise capacity in patients with severe chronic angina, according to a new study. ...

Maternal diet restriction raises the risk for neural tube defects.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Maternal diet restriction raises the risk for neural tube defects. "The authors examined whether maternal dieting behaviors were associated with increased neural tube defect (NTD) risk among...

Cardiological device company expects to report 115% increase in revenues.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Cambridge Heart, Inc., (CAMH) announced that it expects to report revenues in excess of $2,300,000 and for the 3-month period ended December 31, 2003. This would represent an increase of...

Data shows CF101 to be effective in restraining growth of certain cancers.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Can-Fite BioPharma announced new preclinical study results, published in three peer reviewed, high score scientific journals: the Journal of Biological Chemistry, the British Journal of Cancer, and...

Nematode finding could shed light on BRCA1-involved cancers.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Our common evolutionary heritage with the humble nematode worm is helping unravel one of the key genetic puzzles in breast cancer. For the first time, Cancer Research UK researchers have found a...

Risk differs among specific ethnic subgroups of South Asian women in U.K.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Cancer Research UK scientists have discovered that the risk of breast cancer among South Asian women in Britain differs according to their specific ethnic subgroup. Published in the January 6,...

AED equipment sold to major pharmaceutical firms.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Cardiac Science, Inc., (DFIB), a manufacturer of automated public-access defibrillators (AEDs), announced that it has been awarded multiyear contracts by several pharmaceutical manufacturers, including...

Cardiography technology maker appoints medical director.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- CardioDynamics (CDIC), developer of impedance cardiography (ICG) technology, has appointed Neil W. Treister, MD, MBA, FACC, to fill the newly created position of medical director. This position...

Delivery of 30,000 HydroMed wound dressings made.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- CardioTech International, Inc., (CTE) announced that it has taken delivery of 30,000 of its U.S. Food and Drug Administration (FDA)-cleared HydroMed wound dressings and will begin distribution...

Downstream targets of SIM1 and ARNT2 identified.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Scientists have identified the downstream targets of SIM1 and ARNT2, a pair of transcription factors essential for neuroendocrine cell differentiation. According to a study from the United States,...

Chronic ovarian hyperstimulation may precede a subset of pituitary adenomas.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Researchers say that estrogen is sufficient for the formation of lactotrope adenomas only in animals with a hyperstimulated ovary. "The majority of pituitary adenomas in humans are...

Survival of rectal cancer patients over age 75 has improved.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Improvements in mortality may be related to the shift from postoperative to preoperative radiotherapy, the development of the total mesorectal excision technique, and subspecialization of surgeons in...

Distinct roles for VEGF isoforms in bone development described.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- During bone formation, epiphyseal cartilage is avascular until secondary ossification occurs. Vascularization of this maturing tissue relies on angiogenic recruitment from surrounding vessels. ...