Biotech Week articles from April 2001

Biotech Week archives from April 2001

Protein Identified As Apoptosis Inhibitor.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- by Deborah W. Heinrich, staff medical writer - Researchers at AstraZeneca Pharmaceutical have found a novel apoptosis inhibitor that may be a candidate for cancer gene therapy. Expression of the...

Test Offers Rapid, Accurate Detection Of Extrapulmonary Disease.(tuberculosis )
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - A new test for the detection of extrapulmonary tuberculosis rivals Mycobacterium culture for accuracy, but works as quickly as the acid-fast bacilli smear. ...

Drug Reverses DNA Damage Caused By Sunlight.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- A topical lotion, applied once a day, uses liposomes to deliver DNA repair enzymes into the skin that reverse the DNA damage caused by sunlight. Daniel B. Yarosh, PhD, AGI Dermatics, Inc, announced...

Aerosol Delivery Of Vaccine May Be Ideal For Developing Countries.(measles vaccine )
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - A powder formulation of measles vaccine would be a practical alternative to injectable vaccine in developing countries. Measles still carries a high...

New Implanted Device Under Evaluation.(heart failure )
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- University of California, San Francisco (UCSF), researchers have begun clinical trials on a new device to treat patients with heart failure - a progressive cardiovascular disease affecting more than...

Lipase Inhibitor Can Be Useful Adjunct Treatment, Further Studies Needed.(orlistat )(obesity)
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- by Susan Hasty, staff medical writer Pharmacists reviewing the short clinical history of orlistat have concluded that it can be a useful adjunct treatment for obesity, especially when there are...

DTPa/Hib Single Injection Safer Than DTPw Plus Hib Given Separately.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - A single injection of diphtheria-tetanus-acellular pertussis (DTPa) and Haemophilus influenzae type b conjugate (Hib) vaccine causes fewer local and systemic...

Endothelin Receptor Antagonist Shows Positive Preliminary Results.(Veletri, heart failure)
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Actelion Ltd (ATLN) and Genentech, Inc. (DNA) announced positive results March 20, 2001, from a Phase III trial of the first intravenous, dual endothelin receptor antagonist Veletri (tezosentan) in...

New Study To Investigate Chemokine Inhibitor's Role In Increasing White Blood Cells.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- AnorMED announced March 19, 2001 that it has initiated a new Phase I clinical trial in healthy volunteers to study the white blood cell count increasing effects of AMD-3100, an inhibitor of the CXCR4...

Spacer Improves Surgical Outcomes For Arthrosis In Thumb Basal Joint.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Patients with arthrosis in the basal joint of the thumb who are treated using a new surgical method with an implant (spacer) from Artimplant (Stockholm, Sweden) increase their gripping strength and feel...

Adenosine Receptor Antagonist Protects And Improves Renal Function.(congestive heart failure )
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Biogen, Inc. (BGEN) and CV Therapeutics, Inc. (CVTX) announced March 19, 2001, that positive results were presented at the annual meeting of the American College of Cardiology from a Phase II trial with...

Analysis Suggests pFox Inhibitor Safely Benefits Diabetic Patients.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- CV Therapeutics, Inc. (CVTX) announced March 19, 2001, results from an analysis of the MARISA trial demonstrating that patients with a history of chronic angina and diabetes exhibited a clinical...

Over 20 Clinical Trials Are Underway With Arsenic Trioxide.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Cell Therapeutics, Inc. (CTIC) continues to advance the investigation of Trisenox (arsenic trioxide) injection in the treatment of a variety of blood-related cancers. Recently-initiated studies...

Gene Therapy Clinical Trial Shows Treatment Is Safe, Well Tolerated.(angina pectoris)
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Collateral Therapeutics (CLTX) and Berlex Laboratories, the U.S. affiliate of Schering AG, Germany (SHR) announced on March 19, 2001, that results of a Phase I/II clinical trial of Ad5-FGF4 showed that...

FDA Approves Oligonucleotide To Treat Coronary, Peripheral Bypass Graft Failure.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Corgentech, Inc., announced March 20, 2001, that the U.S. Food and Drug Administration (FDA) has granted fast track designation for the company's E2F Decoy, designed to prevent vein grafts used in...

FDA Approves Wrist-Worn Device To Monitor Glucose Levels.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration has approved a wristwatch-like device that provides adult diabetics with more information for managing their disease. It is intended for use along with, not as a...

Vaccine Against Seasonal Rhinitis Is Safe.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Dynavax Technologies Corporation announced preliminary results March 20, 2001, at the 57th annual meeting of the American Academy of Allergy, Asthma, and Immunology from a Phase II clinical trial that...

NIH Awards Research Grant For Development Of Cell Signaling Delivery Methods.(Echelon Research Laboratories Inc. )
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Echelon Research Laboratories Inc. has been awarded a Small Business Innovation Research (SBIR) Phase II grant by the National Institute of General Medical Sciences of the U.S. National Institutes of...

Laser Heart Treatment Demonstrates Substantial Relief.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Eclipse Surgical Technologies (ESTI), a medical device company specializing in cardiac angiogenesis, announced on March 19, 2001, promising data from a randomized, double-blinded, independent assessment...

Five-Year Follow-Up Data Support Cryosurgery As Primary Treatment.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Endocare, Inc. (ENDO), a developer of temperature-based treatments for prostate cancer and prostate obstruction, reported March 20, 2001, that new five-year follow-up data showed that cryoablation was...

Researchers Report Results From Cell Therapy Trials.(Parkinson's disease)
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Genzyme General (GENZ), a division of Genzyme Corp., and Diacrin Inc. (DCRN) announced March 16, 2001, that they have completed a preliminary analysis of results from the Phase II clinical trial of...

European Union Grants Ribavirin Orphan-Drug Status Designation.(Hemorrhagic fever with renal syndrome )
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- ICN Pharmaceuticals, Inc. (ICN), announced March 16, 2001, that the European Commission has granted Orphan Drug Status designation in the European Union to intravenous ribavirin (Virazole) 100 mg/ml for...

Anti-CD23 Monoclonal Antibody Demonstrates Safety, Efficacy.(asthma)
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- IDEC Pharmaceuticals Corp. reports results from a single-dose, placebo-controlled, dose-escalating Phase I trial of its investigational agent IDEC-152, a primatized, anti-CD23 monoclonal antibody in...

Slow-Growing Tumors Respond To Vascular Inhibitors.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Slower growing, weakly vascular tumors respond just as well to angiogenic inhibitors as faster growing, highly vascular tumors do, scientists report. A new...

Human Trials Begin For Antisense Drug.(cancer )
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Lorus Therapeutics Inc. announced March 19, 2001, that the U.S. Food and Drug Administration (FDA) has approved the company's Investigational New Drug (IND) application to begin a Phase I clinical trial...

CDC Selects Rapid HIV Testing For Treatment Investigational Device Exemption.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- OraSure Technologies, Inc., announced that the U.S. Centers for Disease Control and Prevention (CDC) has selected the OraQuick HIV-1/2 rapid HIV test to be used in the CDC-sponsored Treatment...

Clinical Trial Begins On Device To Cool Brain To Save Tissue.(stroke)
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Radiant Medical, Inc., which developed a catheter-based cooling technology for the treatment of myocardial infarction, has announced it has received an investigational device exemption (IDE) from the...

Faster Nanowires May Advance Applications For Detecting Glucose, Hormones, Or DNA.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Teeny-tiny wires capable of connecting with the kinds of molecules that make up the human body could be building blocks for what may be among the first nanotechnology applications: biological sensors...

New Drug Therapy Prevents Calcium Overload In Cells.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- An article in the April 1, 2001, issue of Nature Medicine focuses on a new stroke therapy developed by the pharmaceutical company Bristol Myers Squibb. When the blood supply to a certain part of...

Synergy Between VEGF and HGF Enhances Neovascularization.(vascular endothelial growth factor, hepatocyte growth factor)
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Hepatocyte growth factor increases the impact of vascular endothelial growth factor (VEGF) on neovascularization. Scientists at Genentech, Inc., in San...

DNA Assay Better Than Culture For Detection.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - A new DNA test for the simultaneous detection of chlamydia and gonorrhea is comparable to existing DNA assays, and is more sensitive than culture for...

New Egg-Free Flu Vaccine Promising For Those With Egg Allergy.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Researchers in Austria have developed a unique flu vaccine that is made without egg proteins, which can trigger rare, but potentially fatal, allergic reactions in some people. "The development...

Manufacturers To Test Drugs In Children, Elderly.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Amid an explosion of U.S. cases of type 2 diabetes, pharmaceutical companies are testing drugs on two groups once excluded from experiments for safety reasons: children and the elderly. ...

Human Trials Of New Vaccine Technique Prove Promising For Allergy Sufferers.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- For years, efforts to develop improved vaccines for asthma and allergies have been thwarted because the vaccines themselves often cause the very symptoms a person is trying to avoid. At the 57th...

Novel System For Isolation Of Full-Length Adenoviral Genomes Reported.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- by Deborah W. Heinrich, staff medical writer - Researchers at Merck & Co., Inc., have developed a novel system for isolating full-length adenoviral genomes without plaque purification. R. Youil...

Regulatory Proteins Can Disrupt DNA Repair.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - During HIV related lymphomas, the HIV regulatory protein Tat apparently alters the expression of the DNA polymerase [beta] ([beta]-pol) gene. Deepak K....

Angiogenesis Inhibitor Lengthens Median Survival Two-Fold.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- AEterna Laboratories, Inc. (AEL, AELA) reported on March 26, 2001, clinical data from a Phase I/II clinical trial, demonstrating a statistically significant two-fold increase (p[less than]0.01) in...

Antibodies Invoke Cell-Mediated Tumor Killing In Vitro.
April 11, 2001... 2001 APR 11 -- (NewsRx.com & NewsRx.net) -- AltaRex Corp. (AXO, ALXFF) of Waltham, Massachusetts, additional data further explaining its clinical demonstration of effective T-cell activation induced by its [OvaRex.sup.R] antibody. The in...

Safety, Efficacy Tests Begin On Controversial Vaccine.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- New tests on the effectiveness and safety of the anthrax vaccine were scheduled to begin at the end of March 2001. The battery of studies, coordinated by the U.S. Centers for Disease Control and...

Anti-Platelet Agent Enhances Fibrinolytic's Ability To Bust Clots.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Results announced March 18, 2001, at a symposium preceding the 50th Annual Scientific Session of the American College of Cardiology from a study of patients with ST-segment elevation myocardial...

Data Show Compound Inhibits Angiogenesis, Stimulates Apoptosis.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- New preclinical research by scientists from Cell Pathways, Inc. (CLPA) and its collaborators further supports the ongoing clinical investigation of the company's lead investigational drug, Aptosyn[TM]...

Scientists Investigate How 'Knots' In DNA Affect Genes.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- In their search for better ways to combat cancer, scientists are looking at knots in DNA as potential targets for new cancer therapeutics. These knots occur when DNA folds over upon itself,...

Immunotherapeutic Antisense Agent Extends Survival.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Genta, Inc. (GNTA) reported on March 26, 2001, updated results of clinical trials for its immunotherapy drug Genasense[TM] at the annual meeting of the American Association for Cancer Research (AACR)...

Transmucosal Drug To Begin Trials In South Africa.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Hollis-Eden Pharmaceuticals, Inc. (HEPH) March 21, 2001, announced it has received clearance from the South African Medicines Control Council (MCC) to initiate testing of a new transmucosal (buccal)...

Vaccine Against Group A Strep Infections Approved For Phase I/II Clinical Trial.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- ID Biomedical Corp. announced on March 21, 2001, that it has been granted permission by the Therapeutic Products Program of Health Canada to conduct a Phase I/II clinical trial of StreptAvax[TM], a...

Phase I Study Halted After Unexplained Adverse Findings.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Immune Network Ltd. (IMMKF, IMM) reported March 23, 2001, that the company's Canadian Phase I clinical study, dapsone trial, as announced on February 27, 2001, has been halted. The DAD2000...

Peptide-Based Linking Improves Retention Of Radioisotope In Tumors.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Immunomedics, Inc. (IMMU) announced an advance made by the company's scientists in the attachment of iodine-131 (I-131), a potent therapeutic isotope, to antibodies. The improved technique was...

Encapsulated Vincristine To Be Tested In CHOP Therapy.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Inex Pharmaceuticals Corp. (INEX; IEX) announced on March 26, 2001, that a Phase II clinical trial has begun enrolling patients to evaluate its lead product Onco TCS as part of a first-line treatment...

Companies Add 35,054 Clones To Public Gene Databases.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Invitrogen Corp. (IVGN) and GenoScope, France's National Sequencing Center, announced on March 21, 2001, the release into public databases gene sequence data from 35,054 clones related to approximately...

Clinical Trial Gets Underway For Anticancer Drug.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- The biopharmaceutical company MediGene AG (MDG) announced on March 21, 2001, that a Phase I, dose-escalating, clinical trial to determine the safety of a novel anticancer therapeutic, NV 1020, a...

Synthetic Enzyme Improves Efficacy Of Interleukin-2 Therapy.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Advanced skin and end-stage kidney cancer patients may have a better chance of survival with drugs developed from a new synthetic enzyme that significantly improves the effectiveness of existing...

Compounds Demonstrate Strong HBV-Specific Antiviral Activity In Vitro.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Researchers with Mitsubishi-Tokyo Pharmaceuticals, Inc., in Japan reported that certain trifluoroethyl esters of phosphonomethoxyethyl purine derivatives demonstrate strong and specific antiviral...

Beta Radiation Reduces Recurrent Blockage In Angioplasty Patients.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- New research presented March 18, 2001, at the 50th Annual Scientific Sessions of the American College of Cardiology shows that beta radiation significantly reduces the risk of in-lesion restenosis...

Second-Generation Cox-2, Other Drug Developments Announced,.
April 11, 2001... 2001 APR 11 -- (NewsRx.com & NewsRx.net) -- Pharmacia Corporation (PHA) announced March 23, 2001 several developments in ongoing pharmaceutical programs. The company said that it has submitted a New Drug Application (HDA) to the U.S. Food...

Immunoglobulin E Test Improves Allergen Screening's Accuracy.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Pharmacia Diagnostics announced on March 26, 2001, that the ImmunoCAP[TM]. allergy blood test has been accepted as a quantitative test by the U.S. Food and Drug Administration (FDA). The test...

Drug Candidate Stimulates Neutrophil Production.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Telik, Inc. (TELK) announced that additional data supporting the potential of its TLK199 product candidate were presented March 23, 2001, at the annual meeting of the American Association of Cancer...

Preliminary Data Reported From Phase II Clinical Study of VX-175.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Preliminary results from a 28-day Phase II clinical study of VX- 175, a prodrug of the HIV protease inhibitor amprenavir, were presented at the 8th Conference on Retroviruses and Opportunistic...

Polymer Gel Holds Promise For Therapeutics Delivery And Tissue Engineering.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- A new polymer-based material with unique gelling properties found useful in medical applications ranging from targeted cancer treatment to tissue engineering has been developed by researchers at the...

Nonviral, Electroporation-Assisted Vaccine Produces 100% Tumor Rejection In Mice.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer -- A plasmid-delivered vaccine consisting of two melanoma tumor antigens enabled mice to completely overcome tumor challenge and even improved survival time for...

Canarypox Virus Vector For IV p53 Vaccine Delivery Safe In Rhesus Macaques.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - A potential anti-cancer vaccine has been shown safe at up to 10 times the required dose in rhesus macaques when administered intravenously, and further trials...

Chick Membranes Useful For Biomaterials And Angiogenic Analyses.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Scientists in Germany say chorioallantoic membranes in chick embryos provide a good way to study the effect of new biomaterials on angiogenesis and...

Oral Vaccine Development Gets A Shot In The Arm From Chitosan Microparticles.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer Microparticles that can entrap vaccine and then release it in the gastrointestinal tract represent an exciting potential carrier for oral immunization, say...

Commonly Used Heparin-Coated Circuits Equally Effective.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - The most widely-used heparin-coated coronary artery bypass circuits produce virtually identical results despite their functional differences, cardiologists in...

Protein Inhibitor Targets Chronic Myeloid Leukemia And Gastrointestinal Stromal Tumors.(Gleevec (formerly known as Glivec))
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- A compound developed to fight one form of leukemia at the molecular level also is working to combat a rare gastrointestinal cancer, report researchers in the April 5, 201, issue of the New England...

License Agreement Signed To Commercialize Intelligent Hearing Aid.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- For someone with partial hearing loss, picking out a voice in a crowded social gathering can be hard, even with the help of a hearing aid. That's about to change in a revolutionary way. Scientists...

Advances Could Mean Longer-Lasting Artificial Hips.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- Researchers in Switzerland are developing new materials that are more "friendly" to the body's lubricating proteins and could make future hip replacements last longer. Each year, more than 300,000...

New Type Of Mass Spectrometry Expands 'Molecular Photography' Options.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net -- Move over Kodak, Vanderbilt University Medical Center investigators have developed a new way to take pictures. Of the molecules in a slice of tissue, that is. The technique, called "Imaging Mass...

Monoclonal Antibody Shows Anti-Angiogenic Activity.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- Abgenix, Inc. (ABGX) announced preclinical study results showing that its investigational human monoclonal antibody, ABX-IL8, blocks angiogenesis and inhibits the growth of human melanoma tumors...

Controlling Inflammation May Yield Better Outcomes.(congestive heart failure )
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- Controlling chronic inflammation in congestive heart failure patients may improve outcomes and survival, according to a study published in the April 2001 issue of the American Heart Journal. ...

Gene Therapy Doubles Survival Time For Brain Cancer Patients.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- Ark Therapeutics, Ltd., announced on April 4, 2002, positive results from a Phase I/IIa clinical trial investigating its new gene medicine treatment, EG009, for malignant glioma, an aggressive form of...

Compound Causes Up To Five-Fold Decrease In Tumor Weight, Volume.
April 18, 2001... 2001 APR 18 -- (NewsRx.com & NewsRx.net) -- Collgard Biopharmaceuticals, Ltd., reports that low doses of its proprietary lead compound, Halofuginone, caused a four- to five-fold decrease in human tumor weight and volume in SCID mice when...

Fallopian Tube Device Gets High Marks From Patients.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- Conceptus, Inc. (CPTS), developer of the Stop[TM] (Selective Tubal Occlusion Procedure) non-surgical permanent birth control device for women, announced that the first interim review of data from the...

Researchers Explain Novel Gene-Shuffling Method.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- Enchira Biotechnology Corp. (ENBC) announced on April 2, 2001, the publication of the first peer-reviewed report documenting the application of the company's Rachitt[TM] (Random Chimeragenesis on...

Preclinical Data Indicate Candidate Vaccine's Ability To Inhibit Viral Mutation.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- Epimmune, Inc. (EPMN) announced on April 2, 2001, positive pre-clinical data on its HIV vaccine, which is designed to directly address the problem of viral mutation. Company scientists reported...

Study Demonstrates Utility of Telomerase Promoter.(in cancer cells)
April 18, 2001... 2001 APR 18- (NewsRx.com & NewsRx.net) -- Geron Corp. (GERN) announced the publication of a study that demonstrates the utility of the human telomerase promoter to drive the preferential expression of therapeutic genes in cancer cells. The...

Combination Antiretroviral Tablet Does Not Alter Pharmacokinetics.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - A single tablet combining doses of abacavir, lamivudine, and zidovudine is equivalent to individual doses of these antiretroviral drugs, according to...

Study Demonstrates Tumstatin-5 Inhibits Blood Vessel Growth Better Than Endostatin.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- flex Oncology, Inc. (ILXO) announced results of a study showing that human tumstatin-5 (tum-5), an endogenous protein derived from a collagen fragment, is an effective inhibitor of turnor-associated...

Data Show Drug Triggers Anti-Angiogenesis, Apoptosis.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- Introgen Therapeutics, Inc. (INGN) announced March 29, 2001, that its gene therapy product candidate INGN 241, Adenoviral-mda7, may offer potential benefits in the treatment of lung cancer. Sunil...

Antisense Drug Normalizes Blood Glucose Levels In Mice.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- ISIS 113715, an antisense inhibitor of the PTP-1B gene, has produced significant therapeutic benefit in multiple animal models of diabetes by normalizing blood glucose and insulin levels, according to...

Researchers Determine 3-D Structure Of Target Protein.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- Karo Bio AB and Abbott Laboratories announced on April 5, 2001, that they have determined the three-dimensional structure of the glucocorticoid receptor (GR), an important target protein for...

Neuroregenerative Drug Enters Clinical Trials.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- NeoTherapeutics, Inc. (NEOT), announced on March 29, 2001, that it has begun a 12-week, double-blind, placebo-controlled Phase II study of Neotrotin in Parkinson's disease. This marks the third...

Study Confirms Link Between Spherons And Senile Plaques.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- A recently completed study has found strong new evidence confirming the link between spherons and senile plaques - the characteristic lesion found abundantly in the brains of patients with Alzheimer's...

Thiazolyl Thiourea Compounds Show Therapeutic Promise.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - A number of thiazolyl thiourea derivatives possess potent and selective HIV inhibitory ability. pharmaceutical researchers report. F.M. Uckun and...

Anti-Lipid Drug Reduces Chance Of Brain Injury After Heart Attack.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- Pfizer, Inc., reported that newly published results of a clinical study showed that patients treated with Lipitor (atorvastatin calcium) upon hospital admission for an acute coronary syndrome (ACS)...