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Study finds that using wakefulness tests to detect daytime sleepiness in drivers may be unreliable.
March 7, 2009... A study in the Feb. 15 issue of the Journal of Clinical Sleep Medicine shows that a 40 minute protocol for the Maintenance of Wakefulness Test (MWT40) is superior to a 20-minute protocol (MWT20) at detecting excessive daytime sleepiness (EDS)...
Journal Chest: February news briefs.(Report)
March 7, 2009... WORLD TRADE CENTER HEALTH EFFECTS LINGER YEARS LATER New research confirms that responders to the World Trade Center (WTC) attack are still experiencing health effects more than 5 years later. In a new study from the Mount Sinai School of...
What is the suppressing effect of the PPAR-gamma ligands on stomach cancer cells?
March 7, 2009... PPAR- gamma is manifested in a variety of tissues and cancer cells and the ligands that activate PPAR- PPAR- are currently being studied as a novel treatment. The PPAR-gamma ligand generally decreases the survival rate of cancer cells via...
Investigators at St. James Hospital have published new data on aneurysm.(Report)
March 7, 2009... According to a study from Dublin, Ireland, "Cumulative radiation dose, cost, and increased demand for computed tomography aortography (CTA) suggest that duplex ultrasonography (DU) may be an alternative to CTA-based surveillance. We compared...
Data on bariatrics detailed by researchers at University of Alabama.
March 7, 2009... "Laparoscopic sleeve gastrectomy (SG) is an accepted bariatric procedure, with an advantaged by a low complication rate. A feared complication is stapler line leak," investigators in the United States report (see also Bariatrics).
...
Leading Healthcare CEOs See Opportunity in Challenges of Financial Crisis.(Company overview)
March 7, 2009... Despite terrific challenges facing them in the global economic crisis, CEOs of health delivery organizations see within it an opportunity for recreating the American healthcare environment into a more integrated system of care that favors...
Researchers from University of Leon report on findings in life sciences.
March 7, 2009... According to a study from Leon, Spain, "Growth of maize (Zea mays L.) callus-culture cells was inhibited using dichlobenil (2,6 dichlorobenzonitrile, DCB) concentrations a parts per thousand yen1 mu M; I (50) value for the effect on inhibited...
Reports from Columbia University highlight recent research in Alzheimer disease.
March 7, 2009... "Amyloid-beta (A beta) peptides are produced in high amounts during Alzheimer's disease, causing synaptic and memory dysfunction. However, they are also released in lower amounts in normal brains throughout life during synaptic activity,"...
Studies in the area of Alzheimer disease reported from Boston University.
March 7, 2009... According to recent research from the United States, "Mints/X11s are neuronal adaptor proteins that bind to amyloid-beta precursor protein (APP). Previous studies suggested that Mint/X11 proteins influence APP cleavage and affect production of...
Research findings from M. Decarvalho et al update understanding of amyotrophic lateral sclerosis.
March 7, 2009... According to recent research published in the journal Muscle & Nerve, "In 38 amyotrophic lateral sclerosis (ALS) patients and 28 controls, we performed motor unit potential (MUP) analysis in the C-6 and T-5 paraspinal and biceps muscles."
...
Research from University of Palermo yields new data on amyotrophic lateral sclerosis.
March 7, 2009... According to recent research published in the European Journal of Neurology, "Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder leading to progressive motor neuron cell death. Etiopathogenesis is still imperfectly known and...
Research results from S.M. Stivaros and co-authors update knowledge of aneurysm.(Report)
March 7, 2009... "The aim of this study was to assess whether the addition of a black blood (BB) sequence to standard three-dimensional time-of-flight (3D-TOF) imaging yields improved quantitative assessment of intracranial aneurysms. Thirty seven patients with...
Researchers from Wake Forest University, Medical Department report details of new studies and findings in the area of aneurysm.(Report)
March 7, 2009... "Novel stratagems to improve the efficacy of platinum coils in occluding cerebral aneurysms have primarily involved coating coils with materials thought likely to provoke more desirable histologic reactions, No investigations to date, however,...
Scientists at University of Cape Town publish new data on aneurysm.
March 7, 2009... According to a study from Cape Town, South Africa, "The International Subarachnoid Aneurysm Trial confirmed endovascular treatment as the treatment of choice for intracranial 'berry' aneurysms. The durability of coiling and the relevance of...
New angiography study findings recently were reported by researchers at University of Berlin.(Report)
March 7, 2009... According to recent research from Berlin, Germany, "Scanning parameters used in multislice computed tomographic (MSCT) coronary angiography should be adapted to patients' heart rates. The aim Of this Study was to evaluate the rate of success of...
Data on angiology published by N. Perezcastellano and colleagues.
March 7, 2009... According to a study from Madrid, Spain, "Currently, selection of the ablation catheter for pulmonary vein (PV) isolation is a matter of choice. To evaluate the efficiency of cooled ablation for PV isolation."
"A prospective randomised...
Researchers from Radboud University detail findings in angiology.
March 7, 2009... According to recent research from Netherlands, "Thijssen DH, Green DJ, Steendijk S, Hopman MT. Sympathetic vasomotor control does not explain the change in femoral artery shear rate pattern during arm-crank exercise."
"Am J Physiol Heart...
Scientists at Duke University target angiology.
March 7, 2009... According to recent research from the United States, "The objective of our study was to review expected findings and complications after thoracic endovascular aortic repair on CT angiography (CTA)."
"Luminal and extraluminal changes to the...
Scientists at University of Helsinki publish research in angiology.
March 7, 2009... "The distal part of the internal carotid artery (ICA) close to the skull base can be reached surgically with different approaches. Exposure using the standard lateral incision is eventually limited by bony structures which preclude the...
Studies from University of California, Medical Department reveal new findings on angiology.(Report)
March 7, 2009... According to recent research from the United States, "High-resolution contrast-enhanced MR angiography (CE-MRA) acquired at 3T exquisitely depict carotid artery (CA) stenosis. In this study, we examined the agreement of different...
Study data from M.E. Zelent et al provide new insights into angiology.
March 7, 2009... According to a study from the United States, "The development of a pseudoaneurysm of the posterior tibial artery is a rare event. In this article, we describe the case of a 63-year-old female with rheumatoid arthritis, who initially presented...
Reports from X.O. Sun and co-researchers add new data to research in angiotensins.(Survey)
March 7, 2009... According to recent research from Berlin, Germany, "Angiotensin-converting enzyme (ACE) demonstrates, besides its typical dipeptidyl-carboxypeptidase activity, several unusual functions. Here, we demonstrate with molecular, biochemical, and...
Studies from Ehime University, Medical Department add new findings in the area of angiotensins.(Report)
March 7, 2009... "We examined the possibility that continuous activation of the human brain renin-angiotensin system causes cognitive impairment, using human renin (hRN) and human angiotensinogen (hANG) gene chimeric transgenic (Tg) mice. Cognitive function was...
Studies conducted at University of Tehran on aphthous stomatitis recently published.
March 7, 2009... According to a study from Iran, "Pemphigus vulgaris (PV) usually presents as non-healing, painful oral erosions, but transient or aphtha-like lesions are not exceptional at the very beginning of the disease leading to the common misdiagnosis of...
Research from M.A. King and co-authors in the area of apoptosis published.
March 7, 2009... "Proteins containing extended polyglutamine repeats cause at least nine neurodegenerative disorders, but the mechanisms of disease-related neuronal death remain uncertain. We show that sympathetic neurons containing cytoplasmic inclusions...
Researchers at Cincinnati Children's Hospital target arteriovenous malformation.
March 7, 2009... According to recent research published in the American Journal of Neuroradiology, "We describe a rare case of a de novo cerebral arteriovenous malformation (AVM) in a 9-year-old girl."
"MR imaging at 6 years of age demonstrated band...
Research on arthritis detailed by scientists at University of Kansas.
March 7, 2009... According to a study from the United States, "Patients with rheumatoid arthritis (RA) and their physicians often disagree as to the success of RA treatment or RA outcomes. However, guidelines (such as EULAR criteria for DAS scores) are heavily...
Study data from Korea University update knowledge of arthritis.
March 7, 2009... In this recent report published in the Journal of Rheumatology, researchers in Seoul, South Korea conducted a study "To determine whether interleukin I (IL-1) polymorphisms confer susceptibility to rheumatoid arthritis (RA). We conducted...
Study findings from A. Berth et al provide new insights into arthroplasty.(Report)
March 7, 2009... "Both bipolar and hemiarthroplasty have been used to treat rotator cuff arthropathy (RCA) of the shoulder in patients with low functional demands. In this study, 41 patients treated with either a bipolar or hemiarthroplasty were selected...
Study results from F. Menegoni and colleagues broaden understanding of ataxia.(Report)
March 7, 2009... According to a study from Italy, "The design of useful and effective treatment strategies for movement disorders largely depends on the ability to objectively quantify changes in performances, providing reliable outcome measures. Evaluation of...
Data on atrial fibrillation reported by researchers at Medical College.(Report)
March 7, 2009... "The development of pulmonary vein stenosis has recently been described after radiofrequency ablation (RF) to treat atrial fibrillation (AF). The purpose of this study was to examine expression of TGF beta 1 in pulmonary vein stenosis after...
New atrial fibrillation research has been reported by scientists at Columbia University.
March 7, 2009... According to recent research from the United States, "Dominant frequency (DF) analysis is sometimes limited in its characterization of atrial fibrillation (AF), thus better methodology is needed. To develop methods for analyzing the AF signal...
Study data from West Virginia University provide new insights into borrelia.
March 7, 2009... "Electron cryotomography was used to analyze the structure of the Lyme disease spirochete, Borrelia burgdorferi. This methodology offers a new means for studying the native architecture of bacteria by eliminating the chemical fixing,...
Scientists at Pennsylvania State University, Medical Department publish new data on cell proliferation.
March 7, 2009... "Opioid growth factor (OGF) is an endogenous opioid peptide ([Met(5)] enkephalin) that interacts with the OGF receptor (OGFr) and serves as a tonically active negative growth factor in cell proliferation of normal cells. To clarify the...
Scientists at Fukuyama University publish research in chromatography.
March 7, 2009... According to recent research published in the Journal of Agricultural and Food Chemistry, "This is a report on the development of immunoaffinity chromatography using a column of silica gel with an immobilized single-chain variable fragment...
Research from K. Stravinskaite and co-researchers in the area of chronic obstructive pulmonary disease described.
March 7, 2009... According to a study from Kaunas, Lithuania, "Cough reflex sensitivity has not been studied extensively in patients with chronic obstructive pulmonary disease (COPD). The aim of the study was to evaluate cough reflex sensitivity to capsaicin in...
Study results from University of Barcelona broaden understanding of community-acquired.
March 7, 2009... "The recent Infectious Disease Society of America/American Thoracic Society guidelines for the management of community-acquired pneumonia (CAP) in adults defined a predictive rule to identify patients with severe CAP to determine the need for...
Studies from Ajinomoto Co., Inc. provide new data on Corynebacterium.
March 7, 2009... According to a study from Kawasaki, Japan, "The twin-arginine translocation (Tat) pathway in Corynebacterium glutamicum has been described previously. The minimal functional Tat system in C. glutamicum required TatA and TatC but did not require...
Scientists at National University detail research in endocytosis.(Report)
March 7, 2009... "The Prk1 family of protein kinases are important regulators of endocytosis and actin cytoskeleton in some eukaryotic cells. In budding yeast, Prk1p phosphorylates numerous endocytic proteins including Pan1p and Sla1p," researchers in...
Studies from J.F. Abenza and colleagues reveal new findings on endocytosis.
March 7, 2009... According to recent research published in the journal Traffic, "In fungal hyphal cells, intracellular membrane trafficking is constrained by the relatively long intracellular distances and the mode of growth, exclusively by apical extension....
Findings from Ruhr University advance knowledge in enzyme research.
March 7, 2009... "Electrical synapses can undergo activity-dependent plasticity. The calcium/calmodulin-dependent kinase II (CaMKII) appears to play a critical role in this phenomenon, but the underlying mechanisms of how CaMKII affects the neuronal gap...
New enzyme research research from T.K. Bagui and co-researchers described.
March 7, 2009... "How mitogens reduce the abundance of the cell cycle inhibitor p27(Kip1) is an important question, and regulation of p27(Kip1) translation and turnover has been described. Here we show that platelet-derived growth factor (PDGF) reduces the...
Scientists at University of Toronto target enzyme research.
March 7, 2009... "Cryptosporidiosis is a neglected disease without a wholly effective drug. We present a study demonstrating nitrogen-containing bisphosphonates (N-BPs) to be capable of inhibiting Cryptosporidium parvum at low micromolar concentrations in...
Studies conducted at Columbia University on enzyme research recently published.(Report)
March 7, 2009... "Tobacco-related diseases are leading causes of death worldwide, and many are associated with expression of matrix metalloproteinase-1 (MMP-1). We have reported extracellular signal-regulated kinase (ERK)1/2-dependent induction of MMP-1 by...
Brigham Young University details research in Escherichia coli.
March 7, 2009... According to a study from the United States, "Expression of the Pho regulon in Escherichia coli is induced in response to low levels of environmental phosphate (Pi). Under these conditions, the high-affinity PstSCAB(2) protein (i.e., with two...
Findings in Escherichia coli reported from University of Dundee.
March 7, 2009... "The thiamine diphosphate (ThDP) and metal-ion-dependent enzyme succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxyl ate synthase, or MenD, catalyze the Stetter-like conjugate addition of a-ketoglutarate with isochorismate to release...
Research data from T.S. Moon and colleagues update understanding of Escherichia coli.
March 7, 2009... "A synthetic pathway has been constructed for the production of glucuronic and glucaric acids from glucose in Escherichia coli. Coexpression of the genes encoding myo-inositol-1-phosphate synthase (Ino1) from Saccharomyces cerevisiae and...
Scientists at Medical College of Wisconsin, Medical College report research in Escherichia coli.
March 7, 2009... According to recent research from the United States, "ATP-binding cassette (ABC) transporters make up one of the largest classes of proteins found in nature, and their ability to move a variety of substrates across the membrane using energy...
Studies from Department of Agriculture reveal new findings on Escherichia coli.
March 7, 2009... "To establish an infection, bacteria must first adapt to the host environment and grow. For mastitis, the media in which bacteria must adapt to is milk," scientists in the United States report (see also Escherichia coli).
"Mammary...
Studies from J. Mcpartland and colleagues provide new data on Escherichia coli.
March 7, 2009... According to a study from the United States, "Unlike other characterized phages, the lytic coliphage N4 must inject the 360-kDa virion RNA polymerase (vRNAP), in addition to its 72-kbp genome, into the host for successful infection. The process...
Data on headache and migraine discussed by researchers at University of Stellenbosch.
March 7, 2009... According to recent research from South Africa, "Headaches and neck pain are reported to be among the most prevalent musculoskeletal complaints in the general population. A significant body of research has reported a high prevalence of...
Data on headache and migraine reported by E. Hazard and co-researchers.(Report)
March 7, 2009... According to recent research from the United States, "Migraine is often perceived as a low-impact condition that imposes a limited burden to society and the health-care system. This study reviews the current understanding of the burden of...
Report summarizes headache and migraine study findings from University of Rochester.
March 7, 2009... According to recent research published in the Journal of Clinical Investigation, "Migraine is an episodic headache disorder affecting as many as 10% of people worldwide. Familial hemiplegic migraine (FHM) is an autosomal dominant subtype of...
Researchers from University of Tehran detail findings in headache and migraine.(Report)
March 7, 2009... According to recent research published in the Southern Medical Journal, "The objective of this Study was to assess the warning signs and symptoms in patients with spontaneous subarachnoid hemorrhage (SAH). Patients admitted with spontaneous SAH...
New hemiplegia study findings have been reported from University of Texas.
March 7, 2009... "Neuromuscular electrical stimulation can improve motor function in those affected by paralysis, but its use is limited by a high rate of muscular fatigue. Variable stimulation patterns have been examined in young adults with and without spinal...
Study results from N. Ohkura et al provide new insights into life sciences.
March 7, 2009... According to recent research published in the Journal of Cellular Biochemistry, "In extraskeletal myxoid chondrosarcoma, a chromosomal translocation creates a gene fusion between EWS and an orphan nuclear receptor, NOR1. The resulting fusion...
Scientists at Tel-Aviv University release new data on male infertility.
March 7, 2009... "The human X chromosome is enriched with testis-specific genes that may be crucial for male fertility. One is the ubiquitin-specific protease 26 (USP26)," scientists in Tel Aviv, Israel report (see also Male Infertility).
"Five frequent...
Data on malignant hyperthermia reported by researchers at University of Nottingham.(Report)
March 7, 2009... According to recent research from Nottingham, the United Kingdom, "This study represents a new approach to characterising patients at risk of malignant hyperthermia (MH) through the use of a recently published method for identifying high-risk...
New mastocytosis study findings have been reported from A. Barker et al.
March 7, 2009... "A case of adult-onset mastocytosis is presented to illustrate the classification, signs, symptoms, workup, treatment, and prognosis for this unusual condition. Although there is 110 cure for mastocytosis, symptoms of histamine release can be...
Research on meningioma detailed by scientists at National Taiwan University.(Report)
March 7, 2009... "Abnormal caloric and vestibular evoked myogenic potential (VEMP) responses are frequently encountered with a large cerebellopontine angle (CPA) schwannoma, while normal caloric responses and abnormal VEMPs are noted with a large CPA...
New research on muscular dystrophy from Lund University summarized.
March 7, 2009... According to recent research from Lund, Sweden, "Deficiency of laminin alpha 2 chain leads to a severe form of congenital muscular dystrophy (MDC1A)."
"Here, we analyzed whether the intrinsic laryngeal muscles (ILM) are spared in the...
Studies from L.G.G.C. Verhoef and co-researchers in the area of neurodegenerative disease published.
March 7, 2009... According to recent research from Stockholm, Sweden, "An erroneous transcriptional process, known as molecular misreading, gives rise to an alternative transcript of the ubiquitin B (UBB) gene. This transcript encodes the protein UBB+1, which...
Data from S. Rouatbi et al provide new insights into obstructive sleep apnea.(Report)
March 7, 2009... According to recent research from Sousse, Tunisia, "The objective of this study was to assess whether parameters of the negative expiratory pressure (NEP) technique are able to detect obstructive sleep apnea syndrome (OSAS) in snoring patients....
Researchers' work from Cleveland Clinic focuses on Parkinson disease.
March 7, 2009... "Prevalence rates of depression in medically ill elderly people are strikingly high. In particular, the prevalences of depression at any given time in Alzheimer's, Parkinson's, and stroke are as high as 87%, 75%, and 79%, respectively,"...
Recent findings from University of Groningen highlight research in phosphatase.
March 7, 2009... "CD45 is the most prominent membrane protein on lymphocytes. The function and regulation of this protein tyrosine phosphatase remain largely obscure, mainly because of the lack of a known ligand, and it still remains unknown whether such...
Findings from MassTech, Inc. advance knowledge in proteomics.
March 7, 2009... According to a study from the United States, "The effects of metastable energy level and peptide sequence on the fragmentation patterns of singly charged peptide ions dissociated in collisions with metastable rare gas atoms were studied....
Researchers at University of Pennsylvania target proteomics.
March 7, 2009... "Several neurotransmitters act through G- protein- coupled receptors to evoke a 'slow' excitation of neurons(1,2). These include peptides, such as substance P and neurotensin, as well as acetylcholine and noradrenaline," researchers in the...
Studies from Kyushu University have provided new information about proteomics.
March 7, 2009... According to recent research from Hakozaki, Japan, "The expression of pathogenicity-related extracellular proteases, namely, gelatinase and serine protease, in Enterococcus faecalis is positively regulated by a quorum-sensing system mediated by...
Studies from University of Wisconsin in the area of proteomics published.
March 7, 2009... "We report in vitro (cell-free) protein expression in a microfluidic device using passive pumping. The polystyrene device contains 192 microchannels, each of which is connected to two wells positioned in a 384-well microplate format,"...
Reports from University of Frankfurt highlight recent research in pulmonary embolism.
March 7, 2009... According to recent research published in the European Heart Journal, "Prolonged air travel is considered a risk factor for pulmonary embolism (PE). The clinical characteristics as well as the long-term prognosis of patients suffering from...
Study data from University of California, Medical Department provide new insights into pulmonary fibrosis.
March 7, 2009... "Idiopathic pulmonary fibrosis (IPF) is characterized by progressive (myo)fibroblast accumulation and collagen deposition," scientists writing in the Journal of Clinical Investigation report (see also Pulmonary Fibrosis).
"One possible...
Studies in the area of retinitis pigmentosa reported from University of Pennsylvania.
March 7, 2009... According to recent research published in the journal Eye, " To define molecular and ophthalmic features of a rare phenotype in autosomal dominant ( ad) retinitis pigmentosa ( RP) Methods A 32-year-old woman (proband) with adRP and the...
New strep infection study findings have been reported by researchers at Emory University.(Report)
March 7, 2009... According to a study from the United States, "It has been proposed that the relative scarcity of Staphylococcus aureus and Streptococcus pneumoniae cocolonization in the nasopharynxes of humans can be attributed to hydrogen peroxide-mediated...
Reports from G.D.R. Camacho et al highlight recent research in tuberculosis.
March 7, 2009... According to recent research from Marbella, Spain, "Interpretation of tuberculin tests (TSTs) can be difficult. However, it is even more difficult to classify an individual as infected or non-infected if he or she has undergone a prior TST, as...
Researchers at University of Tennessee publish new data on pediatric otorhinolaryngology.
March 7, 2009... According to recent research published in the International Journal of Pediatric Otorhinolaryngology, "Suprastomal tracheal, granuloma/fibroma (SSTGF) is a common cause of failure to decannulate following pediatric tracheostomy. Because larger...
Recent findings from University of Szeged, Department of Medical Chemistry highlight research in Alzheimer disease.
March 7, 2009... Investigators publish new data in the report 'An intraperitoneally administered pentapeptide protects against Abeta (1-42) induced neuronal excitation in vivo.' "The underlying cause of Alzheimer's disease (AD) is thought to be the accumulation...
Study findings from University of Gothenburg, Sahlgrenska Academy broaden understanding of Alzheimer disease.
March 7, 2009... A new study, 'Synaptic retrogenesis and amyloid-beta in Alzheimer's disease,' is now available. "Pathological hallmarks of Alzheimer's disease (AD) include synaptic and neuronal degeneration and the presence of extracellular deposits of...
New complex regional pain syndrome research from University of Foggia described.
March 7, 2009... Data detailed in 'Role of biphosphonates and lymphatic drainage type leduc in the complex regional pain syndrome (shoulder-hand syndrome)' have been presented. According to recent research published in the journal Pain Medicine, "Complex...
Reports outline dislocations study findings from O.A. Olakulehin and colleagues.(Report)
March 7, 2009... Research findings, 'Case study: report of nine cases of posterior hip dislocations in a single accident involving a modified minibus,' are discussed in a new report. According to recent research published in the journal Traffic Injury...
Studies from C.H. Chou et al in the area of headache and migraine described.(Clinical report)
March 7, 2009... Current study results from the report, 'Throbbing pain is related to Queckenstedt's test effect in migraine patients,' have been published. According to a study from Taiwan, "The Queckenstedt's (Q)-test can aggravate headache intensity during...
Researchers at Obafemi Awolowo University target life sciences.(Clinical report)
March 7, 2009... Fresh data on life sciences are presented in the report 'A prospective multicenter study of injury profile, severity and risk factors in 221 motorcycle-injured Nigerian maxillofacial patients.' According to recent research from Ile-Ife,...
Researchers at Hospital for Sick Children publish new data on salmonellosis.
March 7, 2009... Fresh data on salmonellosis are presented in the report 'Salmonella-containing vacuoles display centrifugal movement associated with cell-to-cell transfer in epithelial cells.' According to a study from Toronto, Canada, "Intracellular...
NBA All-Star 2009 and Daytona 500 Pushes AutoTrader.Com to Record Traffic, Sessions and Page Views.
March 7, 2009... On Monday, February 16, AutoTrader.com, the ultimate automotive marketplace, experienced an all-time record number of car shoppers: 974,851 unique visitors, 1,199,515 sessions and 19,796,740 page views. AutoTrader.com attributes these record...
Help Your Pet, Get to the Vet Campaign Foots the Bill, so Pets Don't Pay the Price.
March 7, 2009... Advantage(R) Topical Solution from Bayer Animal Health announced the Help Your Pet, Get to the Vet Campaign with a mission to distribute more than $250,000 in $20 Veterinary Vouchers and offer valuable money-saving information to help offset...