TB & Outbreaks Week articles from October 2003

TB & Outbreaks Week archives from October 2003

Case reopens on Black Death cause.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Fresh controversy has broken out over the cause of the Black Death that killed up to half the people in Europe in 1348 and circulated for centuries after that. For a century, the blame has rested...

Lower susceptibility of S. pneumoniae associated with increased use of levofloxacin.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- New research shows that the increased use of levofloxacin to treat Streptococcus pneumoniae, the most common bacterial cause of community-acquired pneumonia, has led to a decrease in the...

Better outcomes and cost savings for life-threatening fungal infections.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Data presented at the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) showed that the antifungal treatment voriconazole, a second-generation triazole, is more effective and...

Chickpea-derived peptide has potent and durable antifungal activity.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- A novel peptide derived from chickpeas shows promise as an antifungal agent. "A peptide designated cicerarin, with an N-terminal amino acid sequence VKSTGRADDDLAVKTKYLPP dissimilar from known...

Antibiotics that bind to S. aureus 30S ribosomal subunit also block subunit assembly.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Antibiotics that bind to the S. aureus 30S ribosomal subunit also block the assembly of that subunit. "A number of different antibiotics that prevent translation by binding to the 50S ribosomal...

Lack of funding threatens to derail WHO's Roll Back Malaria program.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- A lack of funding from donor countries may derail the World Health Organization's ambitious anti-malaria program. "The WHO announced the Roll Back Malaria (RBM) movement in 1998, with the goal of...

Some Acanthamoeba strains are different enough to need reclassification.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Two Acanthoamoeba polyphaga strains are different enough to need reclassification, and they may even have different pathogenicity. "The genus Acanthamoeba includes more than 20 morphological...

Guillain-Barre syndrome can occur following Campylobacter infection.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Guillain-Barre syndrome of the axonal pharyngeal cervical brachial type may not have anti-GT1a antibodies, but can have other, anti GM or GD, antibodies. According to published research from Japan,...

CaCo-2 cells have concentration-dependent responses to CPE enterotoxin.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Increasing doses of Clostridium perfringens enterotoxin induce different mitochondrial apoptosis and oncosis pathways in vitro, and thus either may occur in the intestine. "Clostridium perfringens...

Ubiquitin-like peptide with anticancer and immunostimulatory activity isolated from mushroom.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- A novel peptide with anticancer and immunostimulatory activity has been extracted from a common mushroom. In a recent study from China, "A peptide, with a molecular mass of 9.5 kDa and...

Phages point the way to novel targets for antimicrobials.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- By discovering and exploiting the targets that bacteriophages, or bacterial viruses, attack to inhibit microbial growth, scientists at PhageTech, Inc., have identified novel small-molecule compounds...

"Forgotten" malaria still kills millions.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Shivering and sweating feverishly, Felicia Egbuchue took the malaria medicine her doctor prescribed. Although it had cured her in years past, this time it didn't. She was rushed to the hospital, and...

Effects of mutant Neisseria penA on encoded penicillin-binding protein clarified.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- The effects of mutations in the penA gene on the penicillin-binding protein it encodes in Neisseria have been clarified. "Reduced susceptibility to penicillin G in Neisseria meningitidis is...

First ESBL-producing Shigella sonnei strain found in Turkey.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- The first ESBL-producing Shigella pathogen has been identified in Turkey. "A Shigella sonnei strain resistant to cefotaxime and aztreonam (but not ceftazidime) was isolated from the stool sample of...

VIM-1 metallo-beta-lactamase-producing K. pneumoniae found in Greek hospitals.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Klebsiella strains producing the VIM-1 metallo-beta-lactamase have been identified in Greek hospitals According to published research from Greece, in 2002, "seventeen Klebsiella pneumoniae clinical...

WHO chief warns SARS not the last epidemic of the 21st century.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- The head of the World Health Organization (WHO) said the world should be prepared for more deadly epidemics following the SARS outbreak that killed more than 900 people earlier this year. "SARS was...

Imaging system detects contaminants on poultry.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Agricultural Research Service (ARS) scientists in Athens, Georgia, have been granted a patent on an imaging system that detects contaminants on food surfaces. Using a real-time imaging system in the...

Vitamin A deficiency common in HIV, tuberculosis patients in Africa.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- In African patients, HIV and/or tuberculosis infections are associated with vitamin A deficiency. In a recent study from Tanzania, "serum vitamin A was determined" and compared in "100 HIV-positive...

Liver memory CD8 cells protect after treatment with irradiated plasmodial sporozoites.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Liver memory CD8 cells provide antimalarial protection after treatment with irradiated plasmodial sporozoites. Scientists in the United States had previously "demonstrated that protection induced...

Biodefense grant to aid continued development of the GeneCode System.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- EraGen Biosciences, a genetic diagnostics and drug discovery company, announced that the National Institute of Allergy and Infectious Diseases (NIAID), part of the U.S. National Institutes of Health...

First VEB-1-producing Acinetobacter baumannii strain found in French hospital.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- The first known Acinetobacter strain to produce the beta-lactamase VEB-1 has been found in a French hospital. According to published research from France, "twelve clonally related and...

EVIGENE assay provides accurate and convenient MRSA identification.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- The EVIGENE assay provides accurate and convenient MRSA identification. In a recent study from England, "a total of 200 blood cultures containing putative staphylococci were analyzed by a commercial...

Molecular assay can detect and distinguish fecal Giardia duodenalis.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- A novel molecular assay can find and identify Giardia pathogens in fecal samples. According to published research from England, "a nested PCR assay (TPILC-PCR) was developed to detect and...

Molecular blood test suitable for CMV monitoring.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- A novel molecular blood test is suitable for monitoring cytomegalovirus infection. "The measurement of human cytomegalovirus (HCMV) DNA in blood is becoming the standard method for monitoring HCMV...

Adults with asthma fail to follow flu vaccine guidelines.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Adults with asthma are considered a high risk group for developing complications after contracting the influenza virus, yet the majority of adults with asthma does not receive an annual influenza...

Many species of Lactobacillus can cause bacteremia.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Many species of Lactobacillus can cause bacteremia in the immunocompromised. "Six cases of bacteremia in hospitalized patients, five with a depressed immune status, were caused by lactobacilli,"...

Link found to hot water pipes.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Outbreaks of Legionnaires disease are often blamed on germs spewing from air conditioning systems in big buildings, but new research shows home hot water pipes can also be a common source of the...

Hepatic granuloma may be antileishmania defense; IL-4, receptor may be involved.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Hepatic granuloma formation may play a role in antileishmania defense; IL-4 and its receptor IL4Ralpha may play a role in granuloma formation. According to recent research published in the journal...

Telomerase assay detects activity in P. falciparum.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- A novel assay provides fast and accurate assessments of plasmodial telomerase activity. In a recent study from Colombia, "a simple, quick and sensitive method was used to detect telomerase activity...

Aotus infulatus monkeys useful for studying malaria-related anemia.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- A novel animal model may aid research on malaria-related anemia. "Severe anemia is the earliest and a frequently fatal complication of Plasmodium falciparum infection," scientists in Brazil...

Hydroxychloroquine should not be used to treat chloroquine-resistant malaria.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Hydroxychloroquine should not be used to treat chloroquine-resistant malaria. "The 4-aminoquinoline drug hydroxychloroquine (HCQ) is reported to be as active as chloroquine (CQ) against falciparum...

Novel culture augments Artemisia annua artemisinin production.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- A novel culture technique augments artemisinin production. "Artemisinin, an anti-malarial drug isolated from the annual wormwood Artemisia annua L, has a marked activity against...

Polyamine analogues active against resistant P. falciparum.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- A series of novel polyamine analogues have demonstrated promising activity against drug-resistant malaria parasites. "Polyamine biosynthesis and function has been shown to be a good drug target in...

Quinacrine binds to cellular prion protein's C-terminal helix.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- The anti-malarial agent quinacrine binds to the C-terminal helix of the cellular prion protein. "Using NMR [nuclear magnetic resonance] spectroscopy," M. Vogtherr and colleagues at the Swiss...

Measles outbreak reported in a suburb of Tokyo in 1998-1999.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- A measles outbreak occurred in a suburb of Tokyo, Japan, in 1998-1999. According to recent research published in the Scandinavian Journal of Infectious Diseases, "A 1998-1999 outbreak of measles in...

Newly discovered bug ubiquitous in society.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Something called the metapneumovirus, discovered just 2 years ago, is turning out to be an exceedingly common cause of human misery, responsible for garden-variety colds in adults and more severe...

Nanogen teams to develop infectious disease diagnostics.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Nanogen, Inc., (NGEN) and Prodesse, Inc., announced the signing of a collaboration agreement to develop automated, highly sensitive microarray-based products to detect a number of infectious disease...

Anopheles gambiae GST gene mutations can confer DDT resistance.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Mutations in Anopheles gambiae GST genes can provide the malaria vector with resistance to DDT-based pesticides. According to recent research from England, "a cluster of eight genes encoding...

T-cell costimulatory molecule function may determine PCP susceptibility.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- T-cell costimulatory molecule function may determine pneumonia susceptibility in HIV patients. "Loss of T-cell number and function during HIV infection or secondary to pharmacologic...

Augmentin ES-600T more effective than Zithromax in study.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- In a large study of young children with acute otitis media (AOM, or middle ear infections), clinical and bacteriologic outcomes with Augmentin ES-600T (amoxicillin/clavulanate) were statistically...

High-dose steroids, CPAP, strict quarantine helped control Chinese SARS outbreak.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Treatment with high-dose steroids and CPAP ventilation - as well as strict quarantine procedures - helped control a SARS outbreak in China. SARS, "now known to be caused by a coronavirus, probably...

An animal model is found for Q fever endocarditis.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- An animal model is found for Q fever endocarditis, with calcifications and bacteria filled macrophages, as in humans. According to a study from Japan, "Q fever, a worldwide zoonosis caused by...

Chinese province designates 158 hospitals for treating possible future victims.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Southern China's Guangdong province has designated 158 hospitals for treating SARS victims as part of preparations for a possible re-emergence of the disease, official newspapers report. Those...

SBIR grant awarded to develop anti-smallpox therapeutics.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Aphios Corporation has been awarded a phase I Small Business Innovative Research (SBIR) grant for the "Development of Novel Anti-Smallpox Therapeutics from Marine Microorganisms," from the National...

First report of combined spinal subdural tuberculous empyema and intramedullary tuberculoma.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- For the first time, a patient with combined spinal subdural tuberculous empyema and intramedullary tuberculoma has been reported. "Tuberculous involvement of the spinal subdural and intramedullary...

Neurogenesis may be induced in hippocampus soon after bacterial meningitis.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- In experimental Streptococcus pneumoniae induced meningitis, neural progenitors begin differentiation, migration soon after infection; thus there is some hippocampal nerve repair. According to a...

New vaccine reduces antibiotic-resistant infections and protects families.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- A new vaccine introduced nearly 3 years ago has been shown to be effective in reducing antibiotic resistance pneumococcal disease for all ages, particularly for children under 2 years old, according to...

Platelet-activating factor not involved in immune response to TB infection.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Platelet-activating factor (PAF) does not appear to play a role in the immune response to tuberculosis infection. PAF "is a phospholipid with potent, diverse actions, which has been implicated as...

Role of CCL2 in host tuberculosis defense clarified.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- The role of chemokine ligand 2 (CCL2, monocyte chemoattractant protein-1) in host defense against tuberculosis infection has been clarified. "Chemokines play an important role in the development of...

Valpha14 NK T cells may help control inflammation during TB infection.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Valpha14 NK T cells may help control inflammation during TB infection "The possible contribution of NKT cells to resistance to Mycobacterium tuberculosis infection remains unclear," scientists in...

M. tuberculosis capable of gene-selective suppression of IFN-gamma-induced transcription.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Mycobacterium tuberculosis is capable of gene-selective suppression of IFN-gamma-induced transcription. M. tuberculosis "is a highly successful human pathogen," and "a major component of this...

Mycobacterial Nudix hydrolase characterized.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- The mycobacterial Nudix hydrolase MT-ADPRase has been characterized, with results that may aid in the development of anti-tuberculosis agents. "Nudix hydrolases are a family of proteins that contain...

TB not always evident at arrival in new country.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- A paper published by researchers from the U.K. Health Protection Agency, British Thoracic Society, and Department of Health Collaborative Group looked at changes in the number of cases of tuberculosis...

Anti-tuberculous efficacy of fluoroquinolones compared.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- The anti-tuberculous efficacy of several fluoroquinolone antibiotics has been compared, with no clear victor emergent. "Mycobacterium tuberculosis (MTB) is capable of invading not only macrophages...

Fresh-frozen allografts suitable for spinal tuberculosis treatment.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Fresh-frozen allografts are suitable for spinal tuberculosis treatment. In a recent study from South Africa, "one-hundred-twenty-three patients with neurological deficit due to spinal tuberculosis...

Study evaluates "rabbit fever" as part of biodefense research plan.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Since September 11, rabbits have taken on a whole new meaning for biodefense researchers at the University of Missouri-Columbia, who are trying to unravel the science behind rabbit fever, also known as...

Enterocolitis diarrheal symptom may result from expression of chemokine GROalpha.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- Animal models of typhoid fever may vary in diarhheal symptoms due to variation in different species of GROalpha chemokine transcript activity. "Infection of bovine ligated loops with the Salmonella...

CDC: Chickenpox rates drop in 4 states.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- The number of chickenpox cases in four states dropped more than 75% as inoculations became more common in the last decade, according to a new federal study. The total number of cases in Illinois,...

Clinical trial of West Nile virus patients begins.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- AVI BioPharma, Inc., (AVII) has begun dosing patients in a phase Ib clinical trial evaluating its West Nile virus Neugene antisense drug, AVI-4020. AVI is the first company to begin human testing of...

National study planned to evaluate treatment.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- The University of Alabama at Birmingham (UAB) is leading a 35-site study to evaluate the effectiveness of a potential new treatment for West Nile virus. "Animal studies show that viral antibodies...

Test helps protects the nation's blood supply.
October 7, 2003... 2003 OCT 7 - (NewsRx.com & NewsRx.net) -- While September marks the official end of summer, it does not mean the end of mosquito season and the threat of West Nile virus (WNV). More than 80% of the nation's blood supply will continue to be...

Mycobacterial arabinogalactan linkage disaccharide analogs block cell wall biosynthesis.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- Mycobacterial arabinogalactan linkage disaccharide analogs can prevent cell wall biosynthesis. "The mycobacterial arabinogalactan linkage disaccharide [alpha-(L)-Rha-(1 --> 3)-alpha-D-GlcNAc]...

Potent inhibitors of M. tuberculosis TMPK developed.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- Potent inhibitors of mycobacterial TMPK have been developed. "Thymidine monophosphate kinase (TMPK) of Mycobacterium tuberculosis (TMPKmt) represents an attractive target for blocking the...

Rab5 activity, iron access needed for mycobacterial arrest of phagosome maturation.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- Rab5 activity and iron access are needed for mycobacterial arrest of phagosome maturation. "Many mycobacteria are intramacrophage pathogens that reside within nonacidified phagosomes that fuse with...

Azadirachta indica derivatives not practical for malaria treatment.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- Azadirachta indica derivatives are not likely to be practical for malaria treatment. In a recent study from Nigeria, "The antimalarial activities of the tablet suspension of the bark and leaf of...

TDM needed for macrophage infection with M. tuberculosis.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- A key factor needed for macrophage infection by M. tuberculosis has been identified. "The persistence of tuberculosis within pulmonary granulomatous lesions is a complex phenomenon, with bacterial...

M. tuberculosis Rel needed for latent TB infection.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- The mycobacterial Rel protein plays a key role in the development of latent tuberculosis infection. "Long-term survival of nonreplicating Mycobacterium tuberculosis (Mtb) is ensured by the...

Studies to look at role of alcohol in HIV risk in heterosexual women.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- The relationship between drinking and HIV/AIDS in women will be the focus of studies to be conducted under two grants totaling $3.1 million awarded by the National Institute on Alcohol Abuse and...

HIV vaccine candidate trial begins in 18 cities around the world.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- The HIV Vaccine Trials Network (HVTN) and Merck & Co., Inc., announced that they have begun the first global clinical trial of Merck's HIV vaccine candidate in 18 cities around the world. The...

Model predicts optimal antibiotic prophylaxis duration during anthrax outbreak.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- A novel model predicts the optimal duration of antibiotic prophylaxis during an anthrax outbreak. "A critical consideration in effective and measured public health responses to an outbreak of...

Gram-positive bacterial cell walls are identified by innate immune sensors.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- Innate sensors identifying Gram-positive bacterial cell walls account for the strong immune response to these bacteria. According to recent research from Germany, "More than half of invasive...

Terbinafine safe, effective in children.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- Terbinafine is safe and effective in children "Terbinafine is an allylamine antifungal agent that has been effective and safe in the treatment of superficial and some deep mycotic infections in...

Burkholderia cepacia is an increasing problem in CF, immunodeficient patients.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- Burkholderia cepacia, a naturally antimicrobial resistant pathogen, is increasingly a problem in cystic fibrosis and immunodeficient patients. "Although sporadic human infection due to Bulkholderia...

G-CSF given before or with ceftazidime provides no added benefit against melioidosis.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- G-CSF given before or during ceftazidime gave no added benefit in an animal model of melioidosis. "Burkholderia pseudomallei, the causative agent of melioidosis, is an important pathogen in...

Paired DTD values can differentiate catheter and non-catheter bacteremia.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- The continuous read blood culture system, using paired blood cultures with difference in time of detection, can differentiate between catheter-origin and systemic bloodstream infections. According...

Babies exposed to Kingella kingae are susceptible to disease after 6 months.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- Once maternal antibody is gone, babies exposed to Kingella kingae are susceptible to disease, but normally infection is not symptomatic. According to recent research from Israel, "The immune...

Dose-ranging study of CholeraGarde confirms immunogenicity.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- Avant Immunotherapeutics, Inc., (AVAN) presented the full study results of a dose-ranging, immunological study of the company's oral cholera vaccine candidate, CholeraGarde, in healthy volunteers as a...

Dendritic cells have defined subsets that are specialized; some fight viruses.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- Dendritic cells have defined subsets that are specialized; some fight viruses. "Dendritic cells orchestrate the adaptive immune response," scientists in Australia report. "As well as...

Cervicofacial actinomycoses are produced by various genera.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- Fermentative actinomycetes of various genera can infect human neck and face; there is a preference for men. According to a study from Germany, "Actinomycoses are sporadically occurring endogenous...

Diasteromeric antimalarial agent developed.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- A pair of novel antimalarial agents has been developed, although their efficacy is limited. According to published research from France, "A concise and efficient synthesis of two simplified...

Jatrorrhizine shows promise as antifungal therapy.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- Jatrorrhizine shows promise as an antifungal therapy. In a recent study from Slovakia, "The crude extract of Mahonia aquifolium (Berberidaceae) stem bark and its components berberine, palmatine...

Novel plant-derived agents inhibit M. tuberculosis growth.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- Novel plant-derived agents have been found to inhibit the growth of M. tuberculosis. According to recent research from the United States, "Bioactivity-guided fractionation of the CH2Cl2/MeOH...

Campaign aims to promote awareness of proper antibiotic use.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- The U.S. Department of Health and Human Services and a consortium of national health organizations are urging consumers to be cautious about their use of antibiotics as the cold and flu season...

Health risks from indoor pollution are higher than previously thought.
October 14, 2003... 2003 OCT 14 - (NewsRx.com & NewsRx.net) -- Do you really know what you are breathing when sitting at home? Europeans spend 90% of their time indoors. But closed environments are not always the healthiest. The latest studies on human...