TB & Outbreaks Week articles from February 2001

TB & Outbreaks Week archives from February 2001

Multidrug-Resistance On the Rise in the United States.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- According to recent research from the U.S. Centers for Disease Control and Prevention (CDC), multidrug-resistant strains of Streptococcus pneumoniae...

Systemic and Mucosal Immunizations Induce Protective Immune Responses.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Vaccines against Streptococcus pyogenes have been evaluated in an animal model. "The purpose of this study was to examine the suitability of...

Antigen May be Possible Vaccine Candidate.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- According to a study from England, a major secreted mycobacterial antigen (Ag) may have potential as a candidate vaccine against tuberculosis. ...

Malnourished in Indonesia Often Suffer Active Pulmonary TB.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- According to a study from The Netherlands, poor micronutrient status haunts patients in Indonesia with active pulmonary tuberculosis (TB). ...

Many Opportunities Missed for Preventing TB in Kids.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Many opportunities to prevent tuberculosis (TB) in children under five are overlooked in the United States. "Childhood TB is an important...

Prime-Boost Regimens Enhance DNA Vaccine Efficacy.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Knowing when, how much, and how often helped researchers in England improve the immunogenicity and efficacy of a DNA vaccine against Mycobacterium...

T-Cell Expression Cloning Used to Create Novel Vaccine.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- According to a study from the United States, advances in technology are facilitating the development of novel and effective vaccines against...

Auxotrophic Mutants Evaluated as Vaccine Candidates.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Researchers in England report that disruption of genes responsible for virulence of Mycobacterium tuberculosis may result in mutants useful as vaccine...

Latent Reservoirs of Pathogen May Hide in Dendritic Cells.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Dendritic cells (DC) apparently do not clear mycobacterial infections as readily as macrophages. "The interaction of microbes with dendritic cells...

Study Suggests How Cholera Returned to Latin America After 100-Year Hiatus.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- After a century of absence, Vibrio cholerae - the microbe responsible for cholera - invaded the Western Hemisphere by way of Peru in late January 1991. Although a number of theories about the...

Tuberculosis Case Rates at Highest Since 1983.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- Latest figures from the U.K.'s Public Health Laboratory Service (PHLS) show that cases of tuberculosis in Britain are at their highest since 1983. The provisional data for the year 2000 show a...

Killed Vaccine Deemed Protective in Clinical Trial.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- According to a study from Colombia, a population-based trial of a killed Leishmania amazonensis vaccine should be initiated based on the results of...

DNA Immunization Induces Protective Immunity Against Plasmodium falciparum.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Can a DNA vaccine against malaria work? Researchers in France say yes. "DNA-based immunization of mice by Plasmodium falciparum liver-stage...

DNA Persists in Normal Lung Tissue During Latent Infection.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- According to a study from England, Mycobacterium tuberculosis DNA can persist in seemingly healthy lung tissue. "A third of the world's population...

Granulysin Kills Bacteria by Altering Membrane Permeability.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Researchers in the United States reported the discovery of a novel antimicrobial protein with efficacy against Escherichia coli and Mycobacterium...

FDA Approves Treatment for Invasive Fungal Infection.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration (FDA) has approved Cancidas (caspofungin acetate) Intravenous Infusion, an anti-fungal medication for patients who are unresponsive to or cannot tolerate...

Virus Glycoprotein Downregulates Beta 1 Integrins.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- According to a study from the United States, integrins interact with glycoprotein to facilitate Ebola virus entry into cells. "Filoviruses,...

Neutralizing Antibodies Against DPT Induced by Recombinant BCG.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Researchers in Brazil, seeking a new vaccine against diphtheria, pertussis, and tetanus (DPT), put a mutant twist on the old and reliable bacillus...

Vaccine for MMR Supported By Leading Health Organizations.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- Britain's leading health organizations supported the use of the triple vaccine given to young children to protect them against measles, mumps, and rubella (MMR). The Royal College of Nursing...

Costimulatory Molecules Influence Immune Response to Parasite.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- The expression of certain co-stimulatory molecules determine the efficacy of anti-Leishmania immune responses in humans, researchers from the United...

Anti-Glycosylphosphatidylinositol Antibodies are Protective.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Study results indicate anti-glycosylphosphatidylinositols (GPI) antibodies protect against clinical signs of infection. "Induction of...

Influenza Vaccination Reduces Risk of Recurrence.
February 13, 2001... 2001 FEB 13 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Reducing the incidence of upper respiratory infection may reduce the risk of recurrent heart attack. "Numerous studies have suggested that...

Single and Multiple Drug Combinations are Effective Treatment.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Moxifloxacin drug therapy for Mycobacterium avium is effective singly and when combined with ethambutol, researchers in the United States reported. ...

Inhaled Aminoglycosides Evaluated as Adjunctive Salvage Therapy.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Persistent pulmonary tuberculosis infection succumbs to adjunctive salvage therapy, researchers in the United States reported. "A proportion of...

Insecticide-Treated Bed Nets Reduce Morbidity in Endemic Areas.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- A research group from Tanzania and Switzerland confirm that insecticide treated bed nets reduce morbidity in malaria endemic areas. The researchers...

Lab Strain H37Rv and Clinical Isolate CDC 1551 Maintain Similar Traits.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- According to a study from England, two strains of Mycobacterium tuberculosis have maintained genomic similarities although they come from different...

Drugs Have Different Early Bactericidal Activity.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Researchers in South Africa discussed ethical considerations in evaluating antituberculosis drugs. "The early bactericidal activity (EBA) of...

Pathogenic Role of Copper-Zinc Superoxide Dismutase Explored in Mycobacteria.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Copper-zinc superoxide dismutase is not important to the pathogenicity of certain mycobacterial strains, researchers in France report. "Superoxide...

Arboviral Illness Transmitted by Aedes aegypti Mosquitos.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- Medical records in five Laredo, Texas, medical facilities revealed that 50% of suspected dengue fever case-patients examined during one month-long period last summer had undiagnosed dengue fever...

Vaccination Protects Adult Community.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Researchers in Sweden conducted a study to see if adult vaccination could be used to help stem the tide of a diphtheria epidemic in the former Soviet...

Anti-Bacterial Inhibits Parasites that Cause Malaria and Toxoplasmosis.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- Triclosan, a common antiseptic used in household products such as toothpaste, skin creams, and deodorants, kills the parasites responsible for malaria and toxoplasmosis, even at very low...

Chimera Vaccine Evaluated.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Researchers in the United States evaluated different vaccine strains to find the best candidate to provide protection against Japanese encephalitis. ...

Study Indicates Cytokine Status is Not a Prognostic Indicator.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Lung cancer patients have poorer immune profiles than do tuberculosis patients, researchers from Taiwan report. "The present study was designed to...

Treatment Might Include Gene Therapy and Designer Antibiotics.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- Gene therapy to cure hereditary lung disorders, new treatments for asthma, and "designer" antibiotics to eradicate chronic lung infections are among the future advances that might be on the horizon...

Recombinant Vaccinia Virus Vaccine Stimulates Protective Immune Responses.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Researchers in China have developed a malaria vaccine candidate appropriate for clinical trials. "We constructed a live recombinant vaccinia virus...

Symptoms Differ in HIV Patients.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer -- Patients suffering from both HIV infection and tuberculous meningitis have markedly different symptom profiles than HIV negative tuberculous meningitis...

Delayed Antibiotic Treatment is Feasible and Acceptable.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- A "wait and see" approach, compared to immediate prescription of antibiotics for acute otitis media (ear infection) in children, is feasible, acceptable to parents, and should substantially reduce...

Studies Compare Antibiotics for Treatment of Strep Throat, Otitis Media.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- Two comparison studies indicate cefdinir is the preferred antibiotic for treating both otitis media and strep throat. The reports were published in the Pediatric Infectious Disease Journal....

Chronic Stress Modulates Adult Immune Responses.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- According to a study from the United States, adults with chronic stress do not maintain long-term immunity after vaccinations. "Influenza and...

Pesticides Sold in Developing Countries Pose Serious Health Threat.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- Poor-quality pesticides marketed in developing countries are posing a serious threat to human health and the environment, the United Nations Food and Agriculture Organization (FAO) and the World...

Ethnicity an Important Factor in Rates of Gonorrhea and Chlamydia Infections.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- Rates of gonorrhea and chlamydia are about three times as high in black Caribbeans as they are in black Africans in London. Cases of gonorrhea and chlamydia, recorded at 11 sexual health...

Antigenic Specificity of Infected Cells Defined.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- What makes an effective vaccine against Mycobacterium tuberculosis? Researchers in the United States want to know. "Previous studies in murine and...

PCR and Amplicor Facilitate Quick Diagnosis in Children.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- According to a study from Spain, polymerase chain reaction (PCR) and Amplicor tests can provide quick confirmation of Mycobacterium tuberculosis...

Test Aids in Diagnosis and Follow-up.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- According to a study from Germany, a novel test helps researchers differentiate between bone and soft tissue infection of mycobacterial diseases. ...

HLA Class I Polymorphism and Population Genetics Influence Response.
February 20, 2001... 2001 FEB 20 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- According to a study from the United States, genetic differences in populations influence vaccine efficacy. "Human leukocyte antigen (HLA)...