Virus Weekly articles from October 2004

Virus Weekly archives from October 2004

HIV vaccine combination safe and immunogenic in HIV-negative adults.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- An HIV subtype B and E prime-boost vaccine combination was safe and immunogenic in HIV-negative Thai adults. "ALVAC-HIV (vCP1521) and AIDSVAX B/E were evaluated in a phase 1/2 trial of human...

Enterovirus 71 strain causes neurological disease after oral infection.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Enterovirus 71 strain causes neurological disease after oral infection. "A mouse-adapted enterovirus 71 (EV71) strain with increased virulence in mice, MP4, was generated after four serial passages...

Cirrhosis and hepatocellular carcinoma increasing despite HCV infection decline.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Cirrhosis and hepatocellular carcinoma are increasing in Greece, despite a decline in the incidence of HCV infection. "In this study, a comprehensive methodology for modelling the hepatitis C virus...

Roles of IgA and IgG in influenza control in respiratory tract studied.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Researchers have investigated the roles of IgA and IgG in the control of influenza viral infection in the murine respiratory tract. According to published research from the United States, "The...

Immunokinetics in severe pneumonia due to influenza virus/bacteria coinfection.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Immunokinetics in severe pneumonia is a result of influenza virus/bacteria coinfection. According to recent research from Japan, "Coinfections of bacteria and influenza are a major cause of...

Memory CD4+ T cell responses in HIV not restored by antiretroviral therapy.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Central memory CD4+ T cell responses in chronic HIV infection are not restored by antiretroviral therapy. "A strong CD4+ T cell response has been correlated with better control of HIV infection....

Heat shock protein mediates cross-presentation of exogenous HIV antigen.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Heat shock protein mediates cross-presentation of exogenous HIV antigen on HLA class I and class II. According to a study from the United States, "Strong CD4+ and CD8+ T cell responses are...

Immunization with Listeria controls virus load after FIV challenge.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Oral immunization with recombinant Listeria monocytogenes controls virus load after vaginal challenge with feline immunodeficiency virus. "Recombinant Listeria monocytogenes has many attractive...

Papillomavirus-HIV-1 gp41 virus-like particles induce HIV antibodies.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Oral immunization with bovine papillomavirus-HIV-1 gp41 chimeric virus-like particles induced mucosal and systemic neutralizing antibodies against human immunodeficiency virus type 1 (HIV-1). ...

Plasmacytoid dendritic cell activation augments SIV-specific T cells.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- CpG-C immunostimulatory oligodeoxyribonucleotide activation of plasmacytoid dendritic cells in rhesus macaques augments the activation of IFN-gamma-secreting simian immunodeficiency virus-specific T...

DNA binding to viral enzyme may serve as new target for antiviral drugs.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Scientists at the U.S. Department of Energy's Brookhaven National Laboratory and the Albert Einstein College of Medicine have produced the first molecular-scale images of DNA binding to an adenovirus...

Novel podophyllotoxin derivatives have anti-HIV activity.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Novel podophyllotoxin derivatives have anti-HIV activity. According to recent research from the United States, "A series of novel podophyllotoxin derivatives containing structural modifications at...

Recommendations made for two versus three drugs for postexposure HIV prophylaxis.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Recommendations are made for two versus three drugs for postexposure HIV prophylaxis. "Thousands of health care workers are potentially exposed to human immunodeficiency virus (HIV) each year via...

Multiferon is an alternative for treating difficult chronic hepatitis C cases.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Multiferon is an alternative for treating difficult hepatitis C virus cases. According to recent research published in the journal Hepato - Gastroenterology, "a currently 65-year-old patient with...

Interlaboratory results support Hybrid Capture 2 HPV test's reliability.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Interlaboratory results show Digene's Hybrid Capture 2 test is reliable for detecting human papillomavirus DNA in liquid cytology specimens. Researchers at the U.S. National Cancer Institute and at...

Non-European HPV type 16 variants more frequent in invasive disease.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- A study from Italy found non-European variants of human papillomavirus type 16 occurred more frequently in invasive cervical cancer lesions than European variants. "Human papillomavirus type 16...

Rashes from Oka vaccine are derived from single clones of virus.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Rashes occurring after immunization with a mixture of viruses in the Oka vaccine are derived from single clones of the virus. According to recent research published in the Journal of Infectious...

No patterns emerge with viral breakthrough during HCV combination therapy.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- No patterns emerge with viral breakthrough during HCV combination therapy. According to recent research published in the Journal of Medical Virology, "little is known about hepatitis C virus (HCV)...

Personal lubricant has antimicrobial and sperm-inhibiting potential.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Instead, Inc., announced that the U.S. Food and Drug Administration (FDA) has granted clearance to the company to market its personal lubricant product, Amphora. In addition to its lubricating...

RNA interference may protect humans from vector-borne infections.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- RNA interference may protect humans from vector-borne infections. According to a study from the United States, "diseases caused by arthropod-borne viruses are significant public health problems, and...

Biotech holding company receives endorsement of Infectech's Identikit.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Nutra Pharma Corp. (OTCBB:NPHC) announced that its majority owned subsidiary, Infectech, Inc. (Pink Sheets:IFEC) has received third party verification of its technology by Dr. Paul Hyman of Ohio State...

ELVIS plate method is effective in detecting and typing herpes simplex.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Study finds that a commercial enzyme-linked viral inducible system (ELVIS) is a reliable alternative to shell vial culture (SVC) for rapid detection and typing of herpes simplex virus (HSV). "This...

Zinc deficiency impairs immune function and resistance to infection.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Zinc deficiency impairs immune function and resistance to infection. "Zinc is an essential micronutrient for human growth, development, and immune function. Zinc deficiency impairs overall immune...

Substance abuse programs would slow HCV transmissions among homeless men.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Substance abuse programs would slow HCV transmissions among homeless men. According to recent research from the United States, "homeless individuals are at risk for numerous health problems...

Arsenic trioxide inhibits hepatitis C virus replication.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Arsenic trioxide inhibits hepatitis C virus replication. According to a study from Taiwan, "hepatitis C virus (HCV) is a serious global problem, and present therapeutics are inadequate to cure HCV...

Roche and biotechnology company enter antiviral drug discovery partnership.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Roche and SGX (Structural GenomiX) announced an alliance to discover new antiviral therapeutics. Using its proprietary FAST technology, SGX will be responsible for discovering small molecule...

Microparticle encephalitis vaccine elicits mixed immmune response.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- A cationic microparticle-adsorbed plasmid DNA encoding Japanese encephalitis virus envelope protein is immunogenic in mice. "Previously, we described a plasmid pMEa, synthesizing the anchored form...

Enteroviral meningitis outbreak in France is caused by human echovirus 30.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- An enteroviral meningitis outbreak in France is caused by human echovirus 30. According to recent research from France, "Enteroviruses (EVs) are responsible for an array of clinical diseases...

Healthcare corporation issues third quarter update.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Priority Healthcare Corporation (Nasdaq: PHCC) announced that it is adjusting its sales guidance for the third quarter ending on October 2, 2004, due to the delays in shipment and the release of...

Uncooked deer meat consumption presents a risk for hepatitis E virus infection.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Uncooked deer meat consumption presents a risk for hepatitis E virus infection. "It was reported previously food-borne transmission of hepatitis E virus (HEV) to humans from deer meat. The present...

Consistency of treatment for external genital warts is variable in the U.K.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- The consistency of treatment for external genital warts is variable in the United Kingdom. According to recent research from the United States, "Our objective was to identify patterns of treatment...

Antiretroviral therapy is safe for women with HCV infection.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Antiretroviral therapy is safe for women with HCV infection. "To characterize longitudinal hepatic toxicity of antiretroviral therapy in HIV-infected women with and without hepatitis C virus (HCV)...

Declining HIV rates in Uganda a result of availability of cleaner needles.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Declining HIV rates in Uganda are a result of the availability of cleaner needles. According to scientists in Germany, "Public health and political authorities have ascribed the apparent decline in...

Factors associated with short delay between initial HIV test and AIDS elucidated.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- The factors associated with the short delay between initial HIV test and an AIDS-defining event were elucidated. According to a study from France, "A diagnosis of AIDS shortly after the detection...

Unsafe health care fuels HIV epidemics in Africa.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Unsafe health care fuels HIV epidemics in Africa. "Current reconsideration of the contributions of various modes of transmission to HIV epidemics in sub-Saharan Africa has important implications...

Patient-provider relationship must improve to increase long-term quality of life.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Patient-provider relationships must improve in order to increase long-term health-related quality of life of patients. According to recent research from France, "The aim of this study was to...

Normal CD4 and CD8 values established in healthy Chinese adults from Shanghai.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Normal CD4 and CD8 lymphocyte values were established in healthy Chinese adults from Shanghai. "The aim of this study was to establish reference ranges for lymphocyte subsets in Chinese adults,"...

IVDA cessation concomitant with decrease in other addictions and unsafe sex.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Cessation of intravenous drug use is concomitant with a decrease in other addictions and unsafe sex behavior. "This article reports findings from a cohort study that investigated drug injection...

Bivalent miniproteins enhanced anti-HIV activity over monovalent miniproteins.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Bivalent miniproteins show enhanced anti-HIV activity over monovalent miniproteins. According to a study from the United States, "HIV-1 envelope glycoprotein gp120 is displayed as a trimeric complex...

HIV-1 nef effects on CD4 expression/infectivity are independent of rafts.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- HIV-1 nef effects on CD4 expression and infectivity are independent of rafts. According to published research from France, "The HIV-1 Nef protein is a critical virulence factor that exerts multiple...

HIV-specific CTL cultures + IL-7 and IL-15 does not improve cell growth/function.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- HIV-specific cytotoxic T cell cultures with added interleukin 7 and interleukin 15 does not improve cell growth or function. According to recent research from the United States, "The ability to...

Ligands for ICOS potentially suppress HIV-1 replication mainly at entry stages.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Ligands for ICOS potentially suppress HIV-1 replication mainly at the entry stages. According to recent research from Japan, "We investigated the effects of signaling through CD28 family molecules...

Low-level HIV replication in glial cells associated with p55 alterations.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Low-level HIV replication in glial cells is associated with alterations in p55 processing. According to recent research published in the journal Virology, "We report a novel long-lived infection...

Polyanions are able to modulate HIV-1 pathogenesis.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Polyanions are able to modulate HIV-1 pathogenesis. "Polyanions are potent HIV-1 entry inhibitors. Nevertheless, resistant viruses may emerge under polyanion inhibitory pressure. Specifically, a...

Presence of functional vif influences HIV-1 infectivity and disease.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- The presence of functional vif influences HIV-1 infectivity and disease. According to research published in the journal Microbes and Infection, Scientists "analyzed the function of human...

RT residue 215 active in resistance of multidrug-resistant HIV containing i69SS.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- RT residue 215 is active in the resistance of multidrug-resistant HIV containing i69SS. "A two-serine insertion at position 69 (i69SS) of human immunodeficiency virus type 1 (HIV-1) reverse...

Simple model simulates cellular changes in T cells following HIV-1 infection.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- A simple model simulates cellular changes in T cells following HIV-1 infection. "A new mathematical model is presented to simulate various changes of cell pools in the T cell immune system with...

Trim5 alpha protein restricts HIV-1 and murine leukemia virus.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Trim5 alpha protein restricts HIV-1 and murine leukemia virus. "Replication of HIV-1 and N-tropic murine leukemia virus (N-MLV) is restricted in a number of different primate cells. In some cell...

Vif expression controlled to be low and optimal by proteasome degradation.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Vif expression is controlled to be low and optimal by proteasome degradation. According to recent research published in the journal Microbes and Infection, "While the Vif protein of human...

Efavirenz discontinuation associated with multiple factors.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Efavirenz discontinuation is associated with multiple factors. According to recent research from France, "Efavirenz (EFV) is a potent antiretroviral drug; its use may be limited, however, by...

Improved procedures produce good yields of HIV-1 integrase inhibitors.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Improved procedures produce good yields of HIV-1 integrase inhibitors. "A simple and efficient oxalylation of aryl methyl ketones was accomplished with dimethyl oxalate in the presence of sodium...

Traditional healers vital in AIDS prevention and control programs in Africa.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Traditional healers have a vital role in AIDS prevention and control programs in Africa. "Prevention and control programs for HIV/AIDS have had limited success, especially in sub-Saharan Africa. Not...

HIV-related sexual dysfunction in women mainly driven by psychological factors.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- HIV-related sexual dysfunction in women is mainly driven by psychological factors. According to a study from Belgium, "Little is known about female sexual dysfunction (FSD) among HIV-positive women....

OI prophylaxis reduces drug-related toxicity and pharmaceutical interactions.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Prophylaxis of HIV-related opportunistic infections reduces drug-related toxicity and pharmaceutical interactions. According to researchers in France, "Remarkable progress has been made in...

gp120 and NRTIs cause sensory neuron apoptosis through activation of JNK pathway.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- gp120 and nucleoside reverse transcriptase inhibitors cause sensory neuron apoptosis through the activation of the JNK pathway. "Peripheral neuropathy is the most common neurological symptom in...

Strategies to manage patients with viral hepatitis discussed at conference.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- The world's leading hepatitis experts, along with more than 850 physicians, met for the first International Conference on the Management of Patients with Viral Hepatitis. The conference reviewed...

Fully automated test for Hepatitis A virus released.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Abbott Laboratories introduced its second fully automated hepatitis A test in the United States for its widely used AxSYM automated immunoassay instrument system. Used to aid in the laboratory...

High-risk groups for hepatitis B need higher vaccine rates in France.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Greater vaccination coverage of groups at high risk of hepatitis B is needed in France to eradicate hepatitis B transmission. According to recent research from France, "Both HBV plasma derived...

CCR5-Delta32 and CCR2-V641 polymorphisms not related to HCV infection response.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- CCR5-Delta32 and CCR2-V641 polymorphisms are not related to HCV infection response. Chemokine-chemokine receptor interactions are clearly "important in chronic hepatitis C virus (HCV) infection. ...

Dosing complete in phase 1a study of oral HCV protease inhibitor for hepatitis C.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Vertex Pharmaceuticals Incorporated (VRTX) has successfully completed the dosing portion of a phase 1a clinical trial for VX-950, an investigational oral protease inhibitor for the treatment of...

Non-sexual household exposures spawn hepatitis C virus clusters in Pakistan.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Non-sexual household exposures spawn hepatitis C virus clusters in Pakistan. According to recent research from Pakistan, "transmission rates of hepatitis C virus (HCV) infection through non-sexual...

HGV transmitted efficiently via the sexual route.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Hepatitis G virus is transmitted efficiently via the sexual route. According to a study from Lebanon, "The importance of sexual transmission in the epidemiology of hepatitis G virus (HGV) and...

IFN-gamma, TNF-alpha antiviral effects depend on indoleamine 2,3-dioxygenase.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- The antiviral effects of interferon-gamma and tumor necrosis factor alpha on human herpes simplex virus type 2 appear to depend on indoleamine 2,3-dioxygenase activity, according to a study from...

HVS Orf51 protein has role in viral pathogenicity/persistence/cell tropism.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Herpesvirus saimiri Orf51 protein has a role in viral pathogenicity, persistence, and cell tropism. "Herpesvirus saimiri (HVS) is a gamma(2)-herpesvirus sharing genomic colinearity and a high...

Post-transcriptional regulator of KSHV controls gene expression through IRES.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- A posttranscriptional regulator of Kaposi sarcoma-associated herpesvirus controls gene expression through the internal ribosome-entry site. According to recent research from Japan, "Kaposi's...

MAdCAM-1-expressing sacral lymph nodes provide site for immunity.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- The MAdCAM-1-expressing sacral lymph nodes in lymphotoxin beta-deficient mice provide a site for immune generation following vaginal herpes simplex virus-2 infection. According to a study from the...

Marijuana may be useful as an antiviral drug.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- The active ingredient of cannabis, delta-9-tetrahydrocannibol (THC), can prevent the replication and activation of several forms of herpes known to cause cancer, according to new research. This finding...

HIV-1 nef down-regulates antigen-presenting molecules.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Endogenously expressed HIV-1 nef down-regulates antigen-presenting molecules, not only class I MHC but also CD1a, in immature dendritic cells. According to published research from Japan, "The...

HPV 16 L2E6E7 booster vaccine elicits immune response.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- An HPV 16 L2E6E7 booster vaccine elicited an immune response in vulval intraepithelial neoplasia patients previously vaccinated with TA-HPV (vaccinia virus encoding HPV 16/18 E6E7). "Heterologous...

HPV type 16 L1 virus-like particle vaccine may prevent infection.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- A human papillomavirus (HPV) type 16 L1 virus-like particle vaccine shows promise for protection against HPV16 infection. "A post hoc analysis was performed using combined data from two Phase I...

Domestic violence threatens health of children with lower immunization rates.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Domestic violence has an obvious impact on the health and well being of the women being abused, but a new report also highlights important intergenerational effects of such violence: the children of...

New assay for antigenic characterization influenza B virus developed.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Scientists have developed a new microneutralization assay for the antigenic characterization of influenza B virus. According to a study from Italy, "Although the hemagglutination inhibition assay...

Influenza and pneumococcal vaccination lower mortality in elderly.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Influenza and pneumococcal vaccinations lower the mortality of the elderly in Taiwan. According to a study from Taiwan, "In 1998, Taiwan became the first country in Asia to provide free influenza...

Novel HIV glucosidase inhibitors developed with computer-aided technology.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Novel HIV glucosidase inhibitors were developed with computer-aided technology. "Since the onset of the AIDS epidemic, some 20 million people have died and the estimate is that today close to 40...

Biotechnology company challenges validity of Benitec's Australian patent.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Nucleonics, Inc., announced that it has filed with The Commissioner of Patents in Australia a request for reexamination of Benitec and Commonwealth Scientific and Industrial Research Organization's...

Investigational New Drug application filed for macular degeneration trials.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Sirna Therapeutics, Inc., (NASDAQ:RNAI) announced that the company has filed an Investigational New Drug (IND) application with the U.S. Food & Drug Administration (FDA) to begin trials of Sirna-027 in...

Pharma company completes sale of vaccines business to ID Biomedical.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Shire Pharmaceuticals Group plc (Shire) (LSE: SHP, NASDAQ: SHPGY, TSX: SHQ) and ID Biomedical Corporation (ID Biomedical) (TSX: IDB; NASDAQ: IDBE) announced that they have closed the sale of Shire's...

Gains made in controlling mosquito-borne diseases in Australia from 1972 to 2004.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Gains have been made in controlling mosquito-borne diseases in Australia from 1972 to 2004. According to recent research from Australia, "Our paper presents an assessment of research and operational...

Population genetics of Aedes aegypti mosquitoes from Cambodia summarized.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Scientists have compared amplified fragment length polymorphism (AFLP), microsatellite, and isoenzyme markers in populations of Aedes aegypti from Phnom Penh, Cambodia. According to recent research...

Restriction enzyme-based assay can rapidly identify NDV strains.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- A novel restriction enzyme-based assay can be used to rapidly identify virulent strains of Newcastle disease virus (NDV). In a study from Japan, the "[n]ucleocapsid protein (NP) gene" of NDV...

Norovirus gastroenteritis longer in healthcare settings than in healthy persons.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Norovirus gastroenteritis lasts longer in healthcare settings than in healthy persons. According to scientists in England, "Noroviruses are generally believed to cause relatively mild...

Suicide gene therapy containing recombinant viral vector attacks sarcoma.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Suicide gene therapy containing recombinant viral vector attacks sarcoma. "Soft-tissue sarcomas are mesenchymal tumors that respond poorly to systemic chemotherapy. Suicide gene therapy may be an...

The oncolytic adenovirus OAS403 destroys cancer cells.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- The oncolytic adenovirus OAS403 destroys cancer cells. According to recent research published in the journal Cancer Gene Therapy, "a potentially promising treatment of metastatic cancer is the...

Nucleolin plays important role during parainfluenza virus type 3 cellular entry.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Nucleolin plays an important role during human parainfluenza virus type 3 cellular entry. According to recent research published in the Journal of Virology, "Human parainfluenza virus type 3...