Virus Weekly articles from November 2008

Virus Weekly archives from November 2008

New bird flu study findings recently were reported by A.J. Pereda and co-researchers.
November 4, 2008... "Avian influenza (AI) viruses have been sporadically isolated ill South America. The most recent reports are from an outbreak it) commercial poultry in Chile in 2002 and its Putative ancestor from a wild bird in Bolivia in 2001," researchers in...

Studies from University of South Carolina provide new data on bird flu.
November 4, 2008... According to a study from the United States, "This study expands third-person effect research to health news coverage. It examines the perceptual and behavioral components of third-person effects." "Moderator variables of third-person...

Recent findings from Northwestern University, Medical Department highlight research in Epstein-Barr virus.
November 4, 2008... "Latent membrane protein 2A (LMP2A) is a viral protein expressed during Epstein-Barr virus (EBV) latency in EBV-infected B cells both in cell culture and in vivo. LMP2A has important roles in modulating B-cell receptor signal transduction and...

Recent findings from University of Ferrara highlight research in Epstein-Barr virus.
November 4, 2008... Researchers in Ferrara, Italy conducted a study "To evaluate (i) the presence of human herpesvirus 7 (HHV-7), Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV), and (ii) the transcription pattern of HHV-7 in gingival biopsies from...

Reports summarize Epstein-Barr virus research from Harvard University.
November 4, 2008... "The switch from Epstein-Barr virus (EBV) latent infection to lytic replication is governed by two transcriptional regulators, Zta and Rta. We previously reported that the EBV protein encoded by the LF2 gene binds to Rta and can inhibit Rta...

Reports from Brown University advance knowledge in JC virus.
November 4, 2008... According to recent research published in the Journal of Virology, "We studied the susceptibility of human embryonic stem cell-derived oligodendrocyte progenitor cells to infection with JC virus, the causative agent of progressive multifocal...

Data on life sciences discussed by researchers at Technical University.
November 4, 2008... "Through dispersal, deer mice (Peromyscits maniculatus) enter peridomestic settings (e.g., outbuildings, barns, cabins) and expose humans and other deer mouse populations to Sin Nombre virus (SNV). In June 2004, research on deer mouse dispersal...

Studies from Rockefeller University provide new data on multiple sclerosis.
November 4, 2008... "Symptomatic primary Epstein-Barr virus (EBV) infection and elevated humoral immune responses to EBV are associated with an increased risk of developing multiple sclerosis (MS). We explored mechanisms leading to this change in EBV-specific...

Research from Children's Hospital yields new data on paramyxovirus.
November 4, 2008... According to recent research from the United States, "BCX 2798 (4-azido-5-isobutyrylamino-2,3-didehydro-2,3,4,5-tetradeoxy-d-glycero-d-galacto-2-nonulopyranosic acid) effectively inhibited the activities of the hemagglutinin-neuraminidase (HN)...

Research from Monash University in the area of respiratory syncytial virus described.(Report)
November 4, 2008... According to a study from Melbourne, Australia, "Cytoplasmic inclusions in respiratory syncytial virus-infected cells comprising viral nucleocapsid proteins (L, N, P, and M2-1) and the viral genome are sites of viral transcription. Although not...

Scientists at University of Virginia release new data on respiratory syncytial virus.
November 4, 2008... "Human respiratory syncytial virus (HRSV) is released from the apical membrane of polarized epithelial cells. However, little is known about the processes of assembly and release of HRSV and which viral gene products are involved in the...

Scientists at MedImmune, Inc. publish research in influenza immunology.
November 4, 2008... A report, 'Respiratory syncytial virus and influenza virus infections: observations from tissues of fatal infant cases,' is newly published data in The Pediatric Infectious Disease Journal. "Respiratory syncytial virus (RSV) and influenza virus...

Scientists at Imperial College London report research in pediatric in children.(Report)
November 4, 2008... New research, 'Respiratory syncytial virus persistence in chronic obstructive pulmonary disease,' is the subject of a report. "Respiratory syncytial virus (RSV) is predominantly recognized as a pediatric pathogen although sensitive molecular...

Study data from Oxford University provide new insights into life sciences.
November 4, 2008... A report, 'H5N1 transmission and disease: observations from the frontlines,' is newly published data in The Pediatric Infectious Disease Journal. According to recent research published in the The Pediatric Infectious Disease Journal, "Avian...

Investigators at University of Rochester target respiratory syncytial virus in children.
November 4, 2008... Researchers detail in 'Human metapneumovirus infection in adults,' new data in respiratory syncytial virus. "Human metapneumovirus (hMPV) was first identified in 2001 in Dutch children with bronchiolitis. The virus is an RNA virus in the...

Reports on respiratory syncytial virus in children findings from Children's Mercy Hospitals and Clinics provide new insights.(Clinical report)
November 4, 2008... Current study results from the report, 'Comparison of BD Directigen EZ RSV and Binax NOW RSV tests for rapid detection of respiratory syncytial virus from nasopharyngeal aspirates in a pediatric population,' have been published. According to...

Research on adenovirus described by scientists at University of Birmingham.
November 4, 2008... "C-terminal binding protein (CtBP) binds to adenovirus early region 1A (AdE1A) through a highly conserved PXDLS motif close to the C terminus. We now have demonstrated that CtBP1 also interacts directly with the transcriptional activation...

Research results from Royal North Shore Hospital update knowledge of allergies.
November 4, 2008... "Idiopathic environmental intolerance syndrome (IEI), formerly known as multiple chemical sensitivity syndrome (MCSS), and chronic fatigue syndrome (CFS) are controversial diseases and there is little information in the literature regarding the...

New antivirals study findings recently were reported by researchers at Emory University, Medical Department.
November 4, 2008... According to recent research published in the Journal of Experimental Medicine, "Although immunity against intracellular pathogens is primarily provided by CD8 T lymphocytes that recognize pathogen-derived peptides presented by major...

Research from University of Kentucky reveals new findings on arteritis.
November 4, 2008... "The horse-adapted virulent Bucyrus (VB) strain of equine arteritis virus (EAV) established persistent infection in high-passage-number human cervix cells (HeLa-H cells; passages 170 to 221) but not in low-passage-number human cervix cells...

Findings from University of Washington in autoimmune disease reported.
November 4, 2008... According to recent research from the United States, "Detection of nucleic acids and induction of type I interferons (IFNs) are principal elements of antiviral defense but can cause autoimmunity if misregulated. Cytosolic DNA detection...

New chronic fatigue syndrome findings from M. Majer and co-researchers published.
November 4, 2008... In this recent study, researchers in the United States conducted a study "To examine the neuropsychological function characterized in subjects with chronic fatigue syndrome (CFS) at the same time controlling for relevant confounding factors....

New chronic fatigue syndrome research reported from University of Newcastle-upon-Tyne.
November 4, 2008... According to a study from the United Kingdom, "Primary biliary cirrhosis (PBC) is characterized in 95% of patients by autoantibody responses directed against the mitochondrial antigen pyruvate dehydrogenase complex (PDC). Although anti-PDC...

New research on coronavirus from Tsinghua University summarized.(Report)
November 4, 2008... According to recent research published in the Journal of Virology, "The newly emergent human coronavirus HKU1 (HCoV-HKU1) was first identified in Hong Kong in 2005. Infection by HCoV-HKU1 occurs worldwide and causes syndromes such as the common...

Researchers at University of Oslo target cytomegalovirus.
November 4, 2008... According to recent research from Oslo, Norway, "Here, we report the molecular characterization of the human cytomegalovirus uracil DNA glycosylase (UNG) UL114. Purified UL114 was shown to be a DNA glycosylase, which removes uracil from...

Reports outline dengue fever research from T.R. Prestwood and colleagues.
November 4, 2008... According to recent research published in the Journal of Virology, "The four serotypes of dengue virus (DENV1 to DENV4) cause extensive morbidity and mortality. A major obstacle to studying disease pathogenesis and developing therapies has been...

Research data from S.S. Lakdawala and colleagues update understanding of DNA research.
November 4, 2008... According to a study from the United States, "Adenoviruses (Ad) with the early region E4 deleted (E4-deleted virus) are defective for DNA replication and late protein synthesis. Infection with E4-deleted viruses results in activation of a DNA...

New enzyme research findings from University of Connecticut described.
November 4, 2008... "Protein kinase R (PKR) is a central component of the interferon antiviral defense pathway. Upon binding double-stranded RNA (dsRNA), PKR undergoes autophosphorylation reactions that activate the kinase," scientists in the United States report...

Research from Shanghai Jiao Tong University has provided new data on enzyme research.
November 4, 2008... According to a study from Shanghai, People's Republic of China, "The cleavage property of hemagglutinin (HA) by different proteases was the prime determinant for influenza A virus pathogenicity. In order to understand the cleavage mechanism,...

Studies from M. Ciarlet and colleagues provide new data on gastroenteritis.
November 4, 2008... According to a study from the United States, "An ovine rotavirus (OVR) strain, 762, was isolated from a 30-day-old lamb affected with severe gastroenteritis, in Zaragoza, Spain, and the VP4, VP7, VP6, NSP4, and NSP5/NSP6 genes were subsequently...

Research from T. Karlsmark and colleagues has provided new data on herpes labialis.
November 4, 2008... " Hydrocolloid technology has been proven effective in treating dermal wounds. A previous study showed that a newly developed thin hydrocolloid patch [Compeed (R) cold sore patch (CSP)] provided multiple wound-healing benefits across all stages...

Research from Harvard University, Medical Department in the area of herpes simplex virus described.
November 4, 2008... According to recent research published in the journal Proceedings of the National Academy of Sciences of the United States of America, "Viruses remodel the host cell to optimize their replication both by delivery of virion proteins into the...

Studies from Okayama University provide new data on herpes zoster virus.
November 4, 2008... According to a study from Okayama, Japan, "We have established an assay system to detect herpesvirus-derived transcripts in lesional crusts. Fifteen patients with herpes simplex (HS), 21 with herpes zoster (HZ), 2 with varicella, and 20 with...

Data from Logan College of Chiropractic advance knowledge in herpesvirus.
November 4, 2008... According to recent research from Budapest, Hungary, "Two conjugates with epitope peptide (278)LLEDPVGTVA(287) derived from glycoprotein D (gD-1) of Herpes simplex virus (HSV) were synthesized for analysis of the effect of conjugation on...

Findings from K.L. Conn and co-authors broaden understanding of herpesvirus.
November 4, 2008... According to recent research from Edmonton, Canada, "Histones interact with herpes simplex virus type 1 (HSV-1) genomes and localize to replication compartments early during infections. However, HSV-1 genomes do not interact with histones in...

Studies from H. Hofemeister et al further understanding of herpesvirus.
November 4, 2008... According to a study from the United Kingdom, "The mechanism by which herpes simplex virus (HSV) exits the nucleus remains a matter of controversy. The generally accepted route proposes that capsids exit via primary envelopment at the inner...

University of Colorado publishes research in herpesvirus.
November 4, 2008... According to recent research from the United States, "We analyzed the interaction of nucleoside triphosphates (NTPs) containing modified sugars to develop a better understanding of how DNA primase from herpes simplex virus I catalyzes primer...

New findings from Erasmus University describe advances in influenza.
November 4, 2008... According to a study from Netherlands, "Although dendritic cells (DCs) play an important role in mediating protection against influenza virus, the precise role of lung DC subsets, such as CD11b(-) and CD11b(+) conventional DCs or plasmacytoid...

New influenza research has been reported by G.Z. Han et al.
November 4, 2008... According to recent research published in the Virology Journal, "Influenza B viruses cause a significant amount of morbidity and mortality. The occurrence of homologous recombination in influenza viruses is controversial." "To determine...

Reports from University of Warwick advance knowledge in influenza.
November 4, 2008... According to recent research from Coventry, the United Kingdom, "Another influenza pandemic is inevitable, and new measures to combat. this and seasonal influenza are urgently needed. Here we describe a new concept in antivirals based on a...

Research from D. Marsolais et al has provided new information about influenza.
November 4, 2008... "The mechanism by which locally delivered sphingosine analogs regulate host response to localized viral infection has never been addressed. In this report, we show that intratracheal delivery of the chiral sphingosine analog...

Research in the area of influenza reported from Ben-Gurion University.(Report)
November 4, 2008... According to recent research from Beer Sheva, Israel, "Standard operating procedures are the basis of a consistent response to varied threats. The aim of this study is to investigate the relationship between the quality of standard operating...

Research on influenza published by T.G. Sheu et al.
November 4, 2008... According to recent research from the United States, "The surveillance of seasonal influenza virus susceptibility to neuraminidase (NA) inhibitors was conducted using an NA inhibition assay. The 50% inhibitory concentration values (IC(50)s) of...

Research reports from C.S. Lee and co-authors provide new insights into influenza.
November 4, 2008... According to recent research published in the journal Virus Genes, "Several influenza A viral subtypes were isolated from pigs during a severe outbreak of respiratory disease in Korea during 2005 and 2006. They included a classical swine H1N1...

Study data from M. Krasnitz and colleagues update understanding of influenza.
November 4, 2008... "A search of the influenza virus genome database reveals anomalies associated with a nonnegligible number of submitted sequences," researchers in the United States report (see also Influenza). "There are many pairs of viral segments that...

Study results from University of Iowa update understanding of influenza.(Report)
November 4, 2008... "Influenza infections induce a rapid, but transient, dendritic cell (DC) migration from the lungs to the lymph nodes (LNs) that is followed by substantial recruitment of DCs into the lungs without subsequent migration to the LNs. Given that...

Reports outline mental health study findings from Radboud University.(Clinical report)
November 4, 2008... According to recent research published in the journal BMC Health Services Research, "This study investigated the costs and outcomes of implementing cognitive behavior therapy (CBT) for chronic fatigue syndrome (CFS) in a mental health center...

Recent findings in multiple sclerosis described by researchers from University of Cologne.
November 4, 2008... According to recent research published in the Journal of Neurology Neurosurgery and Psychiatry, "A polyspecific, intrathecal humoral immune response against neurotropic viruses such as measles, rubella and varicella zoster virus (MRZ reaction,...

Data from Mie University, Medical Department advance knowledge in paramyxovirus.
November 4, 2008... "The monoclonal antibody M1-1A, specific for the hemagglutinin-neuraminidase (HN) protein of human parainfluenza type 2 virus (HPIV2), blocks virus-induced cell-cell fusion without affecting the hemagglutinating and neuraminidase activities....

Scientists at University of Naples report research in phototherapy.(Report)
November 4, 2008... According to a study from Naples, Italy, "Photodynamic therapy (PDT) involves the use of a photosensitizing agent, which may require metabolic synthesis (i.e. a prodrug), followed by light activation. Numerous studies have advanced PDT as a...

New findings from Kyushu University, Medical Department describe advances in protease.
November 4, 2008... According to recent research from Fukuoka, Japan, "Human metapneumovirus (HMPV) is a major causative agent of severe bronchiolitis and pneumonia." "Its fusion (F) protein must be cleaved by host proteases to cause membrane fusion, a...

Studies from Rockefeller University reveal new findings on retrovirus.
November 4, 2008... "Human endogenous retroviruses (HERVs) comprise approximately 8% of the human genome, but all are remnants of ancient retroviral infections and harbor inactivating mutations that render them replication defective. Nevertheless, as viral...

Study results from Louisiana State University, Medical Department broaden understanding of retrovirus.
November 4, 2008... According to a study from the United States, "Changes in the envelope proteins of retroviruses can alter the ability of these viruses to infect the central nervous system (CNS) and induce neurological disease." "In the present study, nine...

New SARS study findings have been published by scientists at University of North Carolina.
November 4, 2008... According to recent research from the United States, "Zoonotic severe acute respiratory syndrome coronavirus (SARS-CoV) likely evolved to infect humans by a series of transmission events between humans and animals in markets in China. Virus...

Researchers at University of Ghent target vibrio.(Report)
November 4, 2008... According to recent research from Ghent, Belgium, "The concept of polymicrobial disease is well accepted in human and veterinary medicine but has received very little attention in the field of aquaculture. This study was conducted to...

Research from S. Herfst and co-authors provides new data about virology.
November 4, 2008... "Membrane fusion promoted by human metapneumovirus (HMPV) fusion (F) protein was suggested to require low pH (R. M. Schowalter, S. E. Smith, and R. E. Dutch, J. Virol. 80:10931-10941, 2006). Using prototype F proteins representing the four HMPV...

Research from Shiraz University in the area of virology published.
November 4, 2008... According to recent research from Iran, "The complete nucleotide sequence of the genome of wheat Eqlid mosaic virus (WEqMV) (excluding the poly A tail) comprised 9636 nucleotides including 5' and 3' noncoding regions of 137 and 172 nt,...

Scientists at Columbia University publish research in virology.
November 4, 2008... "Varicella-zoster virus (VZV) open reading frame (ORF) 63 protein (ORF63p) is one of six VZV ORFs shown to be transcribed and translated in latently infected human dorsal root ganglia. ORF63p accumulates exclusively in the cytoplasm of latently...

Scientists at University of Maryland release new data on virology.
November 4, 2008... According to a study from the United States, "The genomes of positive-strand RNA viruses undergo conformational shifts that complicate efforts to equate structures with function. We have initiated a detailed analysis of secondary and tertiary...

Studies from Huazhong Agricultural University further understanding of virology.
November 4, 2008... According to a study from Wuhan, People's Republic of China, "Citrus tristeza virus (CTV) isolates collected from southern China were characterized by biological indexing on citrus indicators, restriction fragment length polymorphism (RFLP),...

Studies in the area of virology reported from M. Boyce and co-researchers.
November 4, 2008... According to recent research from London, the United Kingdom, "Bluetongue virus (BTV), an insect-vectored emerging pathogen of both wild ruminants and livestock, has had a severe economic impact in agriculture in many parts of the world. The...

Studies in the area of virology reported from S. Cordierdirikoc and co-researchers.
November 4, 2008... "The involvement of immune cells in prion capture and transport to lymphoid tissues still remains unclear. To investigate the role of dendritic cells (DC), we used DTR+/+ mice, a transgenic model designed to trigger short-term ablation of DC,"...

Reports on west nile virus findings from Washington University, Medical Department provide new insights.
November 4, 2008... "The migration of lymphocytes into the CNS during viral encephalitis is hindered by the blood-brain barrier (BBB) such that most infiltrating cells remain localized to perivascular spaces. This sequestration of leukocytes away from the...

Research from North Carolina State University broadens understanding of west nile virus.
November 4, 2008... According to recent research from the United States, "The innate immune response is the first line of defense against foreign pathogens. The recognition of virus-associated molecular patterns, including double- and single-stranded RNA, by...

Scientists at Washington University, Medical Department describe research in west nile virus.
November 4, 2008... "Type I interferon (IFN-alpha/beta) comprises a family of immunomodulatory cytokines that are critical for controlling viral infections. In cell culture, many RNA viruses trigger IFN responses through the binding of RNA recognition molecules...

Investigators at University of Florida release new data on antivirals.
November 4, 2008... Scientists discuss in 'In vitro susceptibility of sea lion poxvirus to cidofovir' new findings in antivirals. According to recent research published in the journal Antiviral Research, "Parapoxviruses of seals and sea lions are commonly...

New endogenous viruses research from United States Department of Agriculture outlined.
November 4, 2008... Research findings, 'Survey of endogenous virus and TVB* receptor status of commercial chicken stocks supplying specific-pathogen-free eggs,' are discussed in a new report. "Endogenous avian leukosis virus (ALVE) and the ALVE receptor (TVB*S1)...

Studies from Department of Agriculture update current data on endogenous viruses.
November 4, 2008... Researchers detail in 'Development of an endogenous virus-free line of chickens susceptible to all subgroups of avian leukosis virus,' new data in endogenous viruses. "Primary chicken embryo fibroblasts (CEF) from special specific pathogen-free...

Researchers at State University of New York, New York State Department of Health release new data on flavivirus therapy.
November 4, 2008... Investigators publish new data in the report 'Flavivirus methyltransferase: a novel antiviral target.' "Many flaviviruses are significant human pathogens. No effective antiviral therapy is currently available for treatment of flavivirus...

Researchers from University of Technology, Department of Organic Chemistry publish findings in herpes simplex virus.
November 4, 2008... Scientists discuss in 'New organoselenium compounds active against pathogenic bacteria, fungi and viruses' new findings in herpes simplex virus. According to a study from Wroclaw, Poland, "Different N-substituted benzisoselenazol-3(2H)-ones,...

New herpes simplex virus immunology study findings have been reported by scientists at Mount Sinai School of Medicine, Department of Microbiology.(Report)
November 4, 2008... New research, 'Reconsideration of viral protein immunoblotting for differentiation of human herpes simplex viruses,' is the subject of a report. According to recent research from the United States, "Herpes simplex virus type 1 (HSV-1) and type...

Reports outline herpes simplex virus therapy study results from University of Cambridge, Department of Veterinary Medicine.
November 4, 2008... New investigation results, 'Mutations close to functional motif IV in HSV-1 UL5 helicase that confer resistance to HSV helicase-primase inhibitors, variously affect virus growth rate and pathogenicity,' are detailed in a study published in...

New herpesvirus immunology research from University of Washington, Department of Medicine discussed.
November 4, 2008... A report, 'Rapidly cleared episodes of herpes simplex virus reactivation in immunocompetent adults,' is newly published data in The Journal of Infectious Diseases. According to recent research from the United States, "Herpes simplex virus (HSV)...

Reports outline herpesvirus therapy research from Chulalongkorn University, Faculty of Pharmaceutical Sciences.
November 4, 2008... Data detailed in 'Anti-herpes simplex virus (HSV-1) activity of oxyresveratrol derived from Thai medicinal plant: mechanism of action and therapeutic efficacy on cutaneous HSV-1 infection in mice' have been presented. According to recent...

Findings in influenza reported from Capital Medical University.(Report)
November 4, 2008... New research, 'Detection of Haemophilus influenzae type B DNA in a murine pneumonia model by in situ PCR,' is the subject of a report. According to recent research published in the Journal of Medical Microbiology, "This study estimated the...

Investigators at Agricultural Research Service, U.S. Department of Agriculture publish new data on influenza.
November 4, 2008... A report, 'Limited susceptibility and lack of systemic infection by an H3N2 swine influenza virus in intranasally inoculated chickens,' is newly published data in Avian Diseases. According to recent research from the United States, "Chickens...

New influenza research has been reported by scientists at Fordham University, Department of Biological Sciences.(Report)
November 4, 2008... A report, 'Spontaneous and influenza virus-induced sleep are altered in TNF-alpha double-receptor deficient mice,' is newly published data in Journal of Applied Physiology. "Tumor necrosis factor-alpha (TNF-alpha) is associated with sleep...

Researchers' work from University of Pennsylvania, Department of Biology focuses on influenza.
November 4, 2008... A new study, 'Directionality in the evolution of influenza A haemagglutinin,' is now available. According to a study from the United States, "The evolution of haemagglutinin (HA), an important influenza virus antigen, has been the subject of...

Reports summarize influenza therapy study results from University of Michigan, Department of Epidemiology.
November 4, 2008... Scientists discuss in 'Antivirals and influenza: frequency of resistance' new findings in influenza. "Antivirals are effective in prophylaxis and therapy for influenza and are likely to be active against a new pandemic variant. They can be...

New findings from Ludwik Hirszfeld Institute of Immunology and Experimental Therapy in the area of life sciences described.(Report)
November 4, 2008... Research findings, 'Effect of donepezil on innate antiviral immunity of human leukocytes,' are discussed in a new report. "The effect of donepezil on two mechanisms of innate immunity: leukocyte resistance to viral infection and cytokine...

New life sciences research from Swedish University of Agricultural Sciences outlined.
November 4, 2008... Current study results from the report, 'Inactivation of bacteria and viruses in human urine depending on temperature and dilution rate,' have been published. "Source separation and reuse of human urine can decrease the environmental pollution...

New life sciences study findings reported from I. Rochlin and co-authors.
November 4, 2008... Research findings, 'Salt marsh as Culex salinarius larval habitat in coastal New York,' are discussed in a new report. "Culex salinarius is considered one of the most likely bridge vectors involved in the human transmission cycle of West Nile...

Reports summarize life sciences research from Johns Hopkins University.(Report)
November 4, 2008... New research, 'Cognitive representation of orientation: a case study,' is the subject of a report. According to a study from the United States, "Although object orientation in the human brain has been discussed extensively in the literature,...

Reports summarize life sciences study results from INSERM.(Report)
November 4, 2008... New research, 'The transcriptional co-activator PGC-1alpha up regulates apelin in human and mouse adipocytes,' is the subject of a report. "By using pangenomic microarray, we identified apelin as a unique adipokine up regulated by the...