Virus Weekly articles from May 2004

Virus Weekly archives from May 2004

DNA vaccine expressing L1 protein protects against papillomavirus challenge.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- A single vaccination with a vesicular stomatitis virus vector expressing high levels of L1 protein provided complete protection from papillomavirus challenge. "We generated an attenuated,...

Apoptosis may be immune response to HSV infection.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Apoptosis may be an immune response to herpes simplex virus (HSV) infection. Acute HSV infection "causes apoptosis in the adrenal cortex and myenteric plexus of the gut, ovary, pituitary gland, and...

Elderly patients demonstrate blunted response to influenza vaccination.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Elderly patients demonstrate a blunted response to influenza vaccination. According to recent research from the United States, "The objective of this study was to analyze the changes in the type 1 T...

Nedd 4 or ubiquitin ligase Nedd4 regulates human T-cell leukemia virus type 1.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Nedd 4 or ubiquitin ligase Nedd4 regulates human T-cell leukemia virus type 1. "The Gag protein of human T-cell leukemia virus type 1 (HTLV-1) contains the conserved sequences PPxY and PTAP, which...

Bovine herpesvirus 4 persistently infects neuronal cells in vitro.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Bovine herpesvirus 4 persistently infects neuronal cells in vitro. "Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus with no clear disease association. Although BoHV-4 is not considered a...

Antibodies that recognize HIV coreceptor-binding site on gp120 studied.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Scientists describe the structural basis of tyrosine sulfation and V[subscript]H-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 in a recent issue of the...

Attenuated SIV vaccine provides early protection against viral infection.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Vaccination with attenuated simian immunodeficiency virus provided early protection against pathogenic viral infection at a mucosal challenge site. "Atraumatic application of attenuated...

Epitope mimic for human HIV-neutralizing antibody 2G12 synthesized.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Scientists have synthesized a template-assembled oligomannose cluster as an epitope mimic for human HIV-neutralizing antibody 2G12. According to published research from the United States, "The...

HIV synthetic peptide-cocktail prevents SHIV transmission.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- An HIV synthetic peptide-cocktail prevented SHIV transmission in rhesus macaques. "An effective vaccine against human immunodeficiency virus (HIV) should not only protect from infection and...

Low-dose mucosal SIV challenge has same kinetics as high-dose challenge.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Repeated low-dose mucosal simian immunodeficiency virus SIVmac239 challenge results in the same viral and immunological kinetics as high-dose challenge. According to published research from the...

Nasal vaccine controls SHIV viremia and disease progression in primates.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- IL-2-augmented DNA-modified vaccinia virus Ankara nasal vaccination controlled simian/human immunodeficiency virus viremia and disease progression in nonhuman primates. According to recent research...

Bird flu now affecting 25 farms in British Columbia.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- The number of farms infected with bird flu inside British Columbia's Fraser Valley high-risk area has increased to 25, officials said April 12, 2004. The increase, with three new infected sites...

RNA-transfected cells induce responses against viral and tumor antigens.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- RNA-transfected CD40-activated B cells induce functional T-cell responses against viral and tumor antigen targets. "Vaccination with antigen-presenting cells (APCs) engineered to mimic mechanisms...

Agreement signed for HIV molecular diagnostics.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- EraGen Biosciences, a rapidly growing life science company driving a new era in genetic diagnostics and drug discovery, announced they have entered into a collaboration agreement with Emory University...

$1.3M NIH grant awarded to study possible viral role in colon cancer.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- The U.S. National Institutes of Health recently awarded Baylor Research Institute a $1.3 million grant to study a common virus suspected to play a role in causing colon cancer. C. Richard "Rick"...

RNA recombination plays induces genomic change in coxsackie B viruses.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- RNA recombination plays a major role in genomic change during circulation of coxsackie B viruses. According to recent research from the United States, "RNA recombination has been shown to occur...

A new assay is well-suited for routine detection of hepatitis B virus DNA.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- A new assay is well-suited for routine detection of hepatitis B virus DNA. "We report on the development of a fully automated real-time polymerase chain reaction (PCR) assay for the quantitative...

QSAR analysis on anti-HIV HEPT analogues described.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- A QSAR analysis of putative antiretroviral HEPT analogues has been described. According to published research from India, a "Quantitative Structure-Activity Relationship (QSAR) study has been...

Epitope from Epstein-Barr virus protein elicits sustained immune response.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- A novel immunodominant HLA-B*0702-associated epitope derived from an Epstein-Barr virus helicase-primase-associated protein elicited a sustained CD8+ T-cell immune response. "Generation of a...

HIV/gammaretrovirus-based STAR vector packaging system evaluated.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- A novel gene therapy vector system based on gammaretrovirus-psuedotyped HIV has been evaluated. Scientists in England "recently described a novel, stable human immunodeficiency virus type 1 (HIV-1)...

Clues discovered to Trojan horse gene in HIV infection.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Researchers are probing details of how HIV commandeers genes in infected cells to disguise itself from the immune system. The researchers, from The Children's Hospital of Philadelphia, have...

Board recommends dosing of final two patients in VRX496 trial.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- VIRxSYS Corporation announced that the independent Data Safety Monitoring Board (DSMB) unanimously recommended that the remaining two patients in the company's phase I trial be dosed using VRX496...

Early anti-EBV cytotoxic immune response impaired in HIV patients.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- The early cytotoxic response to Epstein-Barr virus (EBV) is impaired in HIV patients. According to recent research from France, "[i]mmunodeficiency related to HIV may increase the incidence of...

NCI awards contract for studies in cancer, AIDS, and AIDS-related illnesses.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Gene Logic, Inc., (GLGC) announced that it has entered into a multiyear agreement with the National Cancer Institute (NCI), division of cancer treatment and diagnosis, to provide preclinical safety and...

E152 amino acid region of HIV integrase characterized.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- The region of HIV integrase carrying the E152 amino acid has been characterized. "HIV-1 integrase (IN) catalyzes the integration of the proviral DNA into the cellular genome," scientists in France...

Muslim areas in Africa have lower rates of HIV infection.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Islam may be linked to reduced rates of HIV infection in Africa. According to researchers in the United States, "[r]eligious constraints on sexuality may have consequences for the transmission of...

Recombinant AAV-2 useful as anti-HIV RNAi vector.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Recombinant AAV-2 is suitable for use as an anti-HIV RNAi vector. According to recent research from Rhode Island, the "cellular introduction of short, interfering RNA leads to sequence-specific...

Rare case of thrombotic thrombocytopenic purpura described.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- A rare case of thrombotic thrombocytopenic purpura underlying thrombocytopenia in a hemophiliac HIV patient has been reported. "Thrombocytopenia is a common complication in human immunodeficiency...

HAART-induced recovery of HIV-specific immunity described.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- The recovery of HIV-specific immune activity in HAART-treated patients has been elucidated. According to recent research from Canada, the "extent to which highly active antiretroviral therapy...

Astrocyte-induced matrix remodeling may mediate HIV-related neurodegeneration.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Astrocyte-induced matrix remodeling may help mediate HIV-related neurodegeneration. According to neurovirologists in France, "[c]hanges in the fine balance between matrix metalloproteinases and...

Dapsone-induced hypersensitivity pneumonitis can mimic PCP.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Hypersensitivity pneumonitis triggered by dapsone exposure can emulate PCP in HIV/AIDS patients. "Interstitial pneumonitis, often related to infectious etiologies, occurs commonly in HIV-infected...

Essential eukaryotic core identified from P. carinii.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Genetic data from Pneumocystis carinii has been used to elucidate the essential eukaryotic core. According to researchers in the United States, P. carinii, an "AIDS-related fungal pathogen," is...

Visceral leishmaniasis relapse common during ineffective HAART.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Relapse of visceral leishmaniasis (VL) is common in HIV patients with a weak response to HAART. According to recent research from Spain, there are "contradictory data about whether highly active...

HIV Tat binds directly to NFkappaB enhancer.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- HIV Tat binds directly to the NFkappaB enhancer. "HIV-1 Tat protein reprograms cellular gene expression of infected as well as uninfected cells apart from its primary function of transactivating...

Antiretroviral therapy does not prevent contingent negative variation.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Antiretroviral treatment does not prevent contingent negative variation abnormalities in HIV patients. In a recent study from California, the "contingent negative variation, an event-related...

Cessation of CMV retinitis therapy has no long-term sequelae for HIV patients.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Cessation of successful CMV retinitis therapy has no long-term sequelae for HIV patients. "Potent antiretroviral therapy stimulates robust and durable immune reconstitution among profoundly...

Dose escalation unnecessary in patients switching to nevirapine from efavirenz.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Dose escalation in not necessary when switching HIV patients to nevirapine from efavirenz treatment. "Efavirenz induces the metabolism of co-administered drugs through the induction of CYP 3A4,"...

Early IL-2 treatment increases CD4 cell count in HIV patients.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Exogenous IL-2 therapy can augment CD4 cell counts in HIV patients undergoing antiretroviral treatment. "Early treatment intervention during human immunodeficiency virus (HIV) infection is a...

In utero AZT exposure has little or no impact on neurodevelopment.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Exposure to the antiretroviral agent azidothymidine (AZT) in utero does not have a significant impact on neurodevelopment. AZT is "administered to pregnant women with HIV to prevent the spread of...

Indinavir superior to ritonavir and saquinavir in triple therapies.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Indinavir is superior to ritonavir and saquinavir as a component of triple antiretroviral regimens. According to a recent study from Spain, the "introduction of the so-called highly active...

Indinavir/ritonavir/efavirenz regimen should benefit treatment-naive patients.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Treatment-naive HIV patients should respond well to a regimen of indinavir and ritonavir at standard dose levels with efavirenz. According to published research from the Netherlands, a...

Pre-HAART IL-7 levels linked to long-term CD4 cell count.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Interleukin (IL)-7 levels prior to HAART initiation are correlated with long-term CD4 cell recovery. "Highly active antiretroviral therapy (HAART) in HIV patients generally increases the CD4 cell...

Surgery can benefit patients with antiretroviral-induced "buffalo hump".
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Surgical intervention is feasible for treatment-induced "buffalo humps" in HIV patients. "Fat redistribution disorders are common complications of antiretroviral therapy," explained C. Gervasoni...

Mycobacteremia among HIV patients in Sao Paulo examined.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- The rate of mycobacterial infections - including tuberculosis - among HIV patients in Sao Paulo has been characterized. "From July 1995 to August 1998, mycobacterial blood cultures were obtained...

Novel CD4+ T-helper lymphocyte epitope identified in hepatitis A virus.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Researchers have identified a novel CD4+ T-helper lymphocyte epitope in the VP3 protein of the hepatitis A virus. According to a study from Spain, "Prediction analysis of Th-cell epitopes in the...

Hepatitis B vaccine decreases hepatitis B incidence in cohort of drug users.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- The incidence of hepatitis B infection has progressively decreased in a cohort of drug users followed over a period of 15 years due to anti-HBV vaccination. According to recent research from Italy,...

Functional hepatitis C virus envelope glycoproteins characterized.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Scientists have characterized functional hepatitis C virus envelope glycoproteins. According to published research from France and the United States, "Hepatitis C virus (HCV) encodes two envelope...

US11 of herpes simplex virus type 1 interacts with HIPK2.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- US11 of herpes simplex virus type 1 interacts with homeodomain-interacting protein kinase 2 (HIPK2) and antagonizes HIPK2-induced cell growth arrest. "HIPK2 is a nuclear serine/threonine kinase of...

B lymphocytes produce normal signals despite hepatitis C virus infection.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- B lymphocytes produce normal signals despite hepatitis C virus infection. "To clarify whether some of the functions of B lymphocytes could be affected during hepatitis C virus (HCV) infection,...

Genetic trick adapted from viruses makes gene-therapy vectors more versatile.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- A genetic trick used by viruses to replicate themselves has been adapted for laboratory use to build complex protein structures required by immune system cells, according to investigators at St. Jude...

Listeria-induced encephalitis can mimic West Nile encephalitis.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Encephalitis caused by Listeria infection can emulate that caused by the West Nile virus. Physicians in New York described the "case of a 50-year-old man who presented to Winthrop University...

Interleukin-1 could be targeted for treating herpes-related stromal keratitis.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Interleukin-1 could be targeted for treating herpes-related stromal keratitis. "Ocular infection with HSV may result in the blinding immunoinflammatory lesion stromal keratitis (SK). This represents...

Flu shot makers say orders for next season filling up fast.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Overwhelming demand for flu shots last season is causing this year's vaccine orders to fill up fast. So much so that there might not be as many extra doses left for sale during the upcoming season. ...

CDC says flu shots will be stockpiled for first time.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- For the first time, the government will stockpile flu shots and will target them toward children to avoid the vaccine shortages that caught health officials off-guard this past winter. "We really...

Neuraminidase-deficient influenza virus is potential vaccine vector.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Scientists have characterized a neuraminidase-deficient influenza A virus that is a potential gene delivery vector and a live vaccine. "We recently identified a packaging signal in the...

Genes from 1918 pandemic influenza virus used to test pathogenicity.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Scientists have investigated the pathogenicity and immunogenicity of influenza viruses with genes from the 1918 pandemic virus. According to a study from the United States, "The 1918 influenza A...

Lytic KSHV infection inhibits host gene expression.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Surprisingly, lytic KSHV infection has been found to suppress gene expression by the host. According to researchers in the United States, the "stimulation of host gene expression by lytic gene...

Prairie dogs transmit monkeypox to humans.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Prairie dogs transmitted monkeypox to humans in the United States. "During May and June 2003, the first cluster of human monkeypox cases in the United States was reported. Most patients with this...

Oncogenesis from single base mutation in IRES of Epstein-Barr nuclear antigen 1.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Oncogenesis develops from a single base mutation in the internal ribosome entry site of Epstein-Barr nuclear antigen 1. Recently published data show that "the U leader exon located within the 5'...

Childhood hepatitis B e antigen seroconversion may be a risk for liver cancer.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Childhood hepatitis B e antigen seroconversion may be a risk for liver cancer. "We prospectively followed 426 children with chronic hepatitis B virus infection. During 6250 person-years, 2 boys...

Pneumococcal vaccine not useful in HIV patients responding to HAART.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- The 23-valent pneumococcal vaccine does not offer additional protection against pneumonia in HIV-infected patients who have an immunological response to highly active antiretroviral therapy (HAART). ...

Only Sabin type 3 polio vaccine strain mutation reduces viral growth.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Only the Sabin type 3 strain mutation significantly reduces viral growth in HeLa and neuroblastoma cells. "Initiation of poliovirus (PV) protein synthesis is governed by an internal ribosome entry...

Complex protein interactions counteract adenovirus-induced inflammation.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Complex protein interactions counteract adenovirus-induced inflammation. "Replication-defective human adenovirus (Ad) group C transducing vectors, most of which have the E1A, E1B, and E3 genes...

Hepatitis C virus core protein intercepts p53 activity to halt apoptosis.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus core protein intercepts p53 activity to halt apoptosis. "The core protein of hepatitis C virus affects several biological functions of the host cells such as cellular growth and...

Up-regulation of ubiquitin-specific protease enhances EBV proliferation in vitro.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Up-regulation of ubiquitin-specific protease enhances Epstein-Barr virus proliferation in vitro. "The family of ubiquitin (Ub)-specific proteases (USP) removes Ub from Ub conjugates and regulates a...

Region of rabies virus glycoprotein plays important pathogenic role.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- A region involving amino acids 164 to 303 of the rabies virus glycoprotein plays an important role in the pathogenicity toward adult mice. According to recent research from Japan, "The authors have...

Anti-LFA-1 delays viral clearance in RSV infection.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Treatment with anti-LFA-1 delays the CD8+ cytotoxic-T-lymphocyte response and viral clearance in mice with primary respiratory syncytial virus (RSV) infection. According to a study from the United...

Antibodies to rotavirus common in non-human primates.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Rotavirus antibodies were common in non-human primates. According to a study from the United States, "Rotavirus and norovirus are associated with a substantial burden of diarrheal disease in humans...

Antibody to S1 protein neutralizes SARS coronavirus.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- A human monoclonal antibody to S1 protein that blocks receptor association neutralized the severe acute respiratory syndrome (SARS) coronavirus. "Effective prophylaxis and antiviral therapies are...

Response to plasmid DNAs encoding SARS-CoV spike gene fragments characterized.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Researchers have characterized the humoral responses in mice immunized with plasmid DNAs encoding SARS-CoV spike gene fragments. "The immunological characteristics of SARS-CoV spike protein were...

Inverse relation between enterovirus antibodies and type 1 diabetes.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Results from the EPIVIR project indicated a significant inverse relation between enterovirus antibody frequency and the incidence of type 1 diabetes. "The incidence of type 1 diabetes varies...

Adenoviral vectors for gene transfer and therapy reviewed.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Scientists review adenoviral vectors for gene transfer and therapy in a recent issue of the Journal of Gene Medicine. "Due to the very efficient nuclear entry mechanism of adenovirus and its low...

Antibodies and CD8+ T cells contribute to immunity to adenovirus vectors.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Neutralizing antibodies and CD8+ T lymphocytes both contribute to immunity to adenovirus serotype 5 vaccine vectors. According to a study from the Netherlands and the United States, "The high...

Hepatitis C virus NS3 protein displays significant genetic variability.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus NS3 protein displays significant genetic variability. "Hepatitis C virus (HCV) variation in specific T-cell epitopes may represent a mechanism of viral persistence in chronic...

Hyperacetylation define classes of acetylated SV40 chromosomes.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Hyperacetylation and differential deacetylation of histories H4 and H3 define two distinct classes of acetylated SV40 chromosomes early in infection. According to recent research published in the...

Lentiviral vectors can be re-engineered to optimize gene delivery.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Lentiviral vectors can be re-engineered to optimize gene delivery. "Vectors derived from retroviridae offer particularly flexible properties in gene transfer applications given the numerous possible...

MyD88 protein suppresses hepatitis B virus replication.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- MyD88 protein suppresses hepatitis B virus replication. "Myeloid differential primary response protein (MyD88) is a critical component in the signaling cascade through Toll-like receptors (TLRs)...

Novel techniques offer state-of-the-art retrovirus vector production.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Novel techniques offer state-of-the-art retrovirus vector production. According to recent research from France, "retroviral vectors are still the vectors that are used in the majority of gene...

Expression of viral peptide animal vaccine achieved in tobacco chloroplasts.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Scientists have produced high-yield expression of a viral peptide animal vaccine in transgenic tobacco chloroplasts. "The 2L21 peptide, which confers protection to dogs against challenge with...

Simian foamy virus infection found in people exposed to primates.
May 4, 2004... 2004 MAY 4 - (NewsRx.com & NewsRx.net) -- Frequent simian foamy virus infection was found in people occupationally exposed to nonhuman primates. "The recognition that AIDS originated as a zoonosis heightens public health concerns...

Fuzeon to be widely available in U.S. pharmacies.
May 11, 2004... 2004 MAY 11 - (NewsRx.com & NewsRx.net) -- Roche and Trimeris (TRMS) announced that Fuzeon (enfuvirtide), the first and only fusion inhibitor available for the treatment of HIV, will be available through retail and specialty pharmacies across...

Viral-induced diabetes is accompanied by phagocytosis of beta cells.
May 11, 2004... 2004 MAY 11 - (NewsRx.com & NewsRx.net) -- The induction of coxsackieviral-mediated diabetes requires antigen-presenting cells and is accompanied by phagocytosis of beta cells. "Epidemiological studies have associated coxsackie B virus...

Researchers look at viral triggers for multiple sclerosis in children.
May 11, 2004... 2004 MAY 11 - (NewsRx.com & NewsRx.net) -- Researchers at the Hospital for Sick Children (Sick Kids) have shown an association between pediatric multiple sclerosis (MS) and the Epstein-Barr virus (EBV), indicating that exposure to the virus at...

Antiretroviral agents may be useful for SARS prevention and treatment.
May 11, 2004... 2004 MAY 11 - (NewsRx.com & NewsRx.net) -- Antiretroviral agents may be useful for SARS prevention and/or therapy. In a recent study, scientists in China "observed that 0 of 19 patients with human immunodeficiency virus type 1 (HIV-1)...