Virus Weekly articles from March 2004

Virus Weekly archives from March 2004

Translation efficiency affects cellular infection in dengue virus strains.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Translation efficiency determines differences in cellular infection among dengue virus type 2 strains. According to recent research published in the journal Virology, "We have investigated the...

Microbead-conjugated anti-gp41 antibodies can isolate HIV-infected cells.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Microbead-conjugated anti-gp41 antibodies can be used to enrich for HIV-infected cells. "The isolation of a pure population of human immunodeficiency virus (HIV)-infected cells is highly desirable...

HBV treatment can lead to recovery of virus-specific T-cell responses.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- HBV treatment can lead to the recovery of HBV-specific T-cell responses in HIV patients. "Liver-related mortality is an increasing problem in human immunodeficiency virus (HIV)/hepatitis B virus...

IFN-gamma from influenza-infected cells stimulates IFN-inducible protein-10.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Interferon-gamma from human endothelial cells infected with influenza A virus stimulate interferon-inducible protein-10 and monokine. "Primary human umbilical vein endothelial cells (HUVECs) were...

Three-year data highlight Viread efficacy, safety, and side effect profile.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Gilead Sciences, Inc., (GILD) announced preliminary 3-year (144-week) data from a double-blind, phase III clinical trial (Study 903) suggesting that Viread (tenofovir disoproxil fumarate) is associated...

Germline transfection is possible after intramyocardial gene delivery.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Germline transfection is possible after intramyocardial gene delivery. According to published research from the United States, "intramyocardial injection of adeno-associated virus (AAV) has been...

Influenza virus enhances asthma.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Asthma in children is increasingly common in Westernized countries. Ironically, the greater prevalence of allergic disease is thought to be due to lifestyle improvements that bring with them better...

Avian flu virus continues to spread in Asian countries.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Despite massive efforts to stamp out the virulent avian influenza virus, the disease continues to spread in poultry-producing areas in some Asian countries, the UN Food and Agriculture Organization...

New Zealand authorities make avian influenza a notifiable disease.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- New Zealand has made avian influenza, or bird flu, a notifiable disease, requiring health authorities to be informed urgently of any actual or suspected cases. New Zealand Health Minister Annette...

HPV, chromosome aberrations correlate with transition to microinvasive carcinoma.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Integration of human papillomavirus (HPV) 16/18 DNA is an important event in the transition of cervical intraepithelial neoplasia (CIN I, II, and III) to microinvasive carcinoma. "Cervical...

In situ hybridization techniques may be able to detect HPV.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- High-risk human papillomaviruses (HPVs) might be detected by sensitive in situ hybridization techniques. "Human papillomaviruses are accepted as a necessary cause of cervical neoplasia. However,...

Phase III CFS clinical trial complete.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Hemispherx Biopharma, Inc., (HEB) has completed the randomization and placebo-controlled dosage stage of its phase III clinical trial for chronic fatigue syndrome (CFS), becoming - according to the...

Antiretroviral mechanisms of DSB identified.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- The antiretroviral mechanisms of the novel agent DSB have been characterized. According to published research from Tennessee, "Despite the effectiveness of currently available human immunodeficiency...

Antiviral and DNA-cleaving activities of fullerene derivatives reviewed.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- The antiviral and DNA-cleaving activities of fullere derivatives have been reviewed. "The fullerene family, and especially C-60, has very appealing photo-, electro-chemical and physical properties,...

Inhibition of HIV integrase by styrylquinoline derivatives characterized.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- The inhibition of HIV IN by styrylquinoline derivatives (SQ) has been characterized. SQ "efficiently inhibit the 3'-processing activity of integrase (IN) with IC50 values of between 0.5 and 5...

Retrovirus vector-delivered RNA interference downregulates gene expression.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Retrovirus vector-delivered RNA interference downregulates gene expression. "RNA interference (RNAi) is the mechanism of sequence-specific, post-transcriptional gene silencing initiated by short...

Bayesian inference used to clarify evolutionary relationship of HIV, SIV.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- A novel Bayesian technique has been used to clarify the evolutionary relationship of HIV and its simian counterpart, SIV. "The most plausible origin of HIV-1 group M is an SIV lineage currently...

CXCR4 mediates gp120 neurotoxicity in cerebellar granule cells.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- CXCR4 mediates HIV gp120-induced neurotoxicity in cerebellar granule cells. "The human immunodeficiency virus type 1 (HIV-1) glycoprotein gp120 causes neuronal cell death; however, the molecular...

AIDS rising in black male college students.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- A sudden, surprising increase in HIV infections has been discovered among male black college students in North Carolina, and officials fear the same is probably happening across the South. The...

HIV rates, risk factors among different IDU types determined.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Patterns of HIV transmission among different classes of injection drug users have been characterized. In a recent study from the United States, the "prevalence of HIV and associated risk behaviors...

Novel gp41-derived peptides inhibit HIV cell entry.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Novel gp42-derived peptides inhibit strongly inhibit HIV-cell membrane fusion. According to a study from Germany, "As the limitations of antiretroviral drug therapy, such as toxicity and resistance,...

HIV among pregnant women at Mexican hospital much higher than reported earlier.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- HIV infection among pregnant women in labor at Tijuana General Hospital in Mexico is 14 times higher than previously reported by CONASIDA, the Mexican organization that tracks AIDS cases, according to a...

Enyzme immunoassay suitable for cryptosporidiosis diagnosis.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Cryptosporidiosis diagnosis through EIA appears to be feasible in HIV patients. Scientists in Brazil conducted a study "to verify the occurrence of Cryptosporidium infection in 52 human...

Prevalence and effects of P. jirovecii DHPS mutations determined.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- The frequency and clinical significance of P. jirovecii DHPS polymorphisms have been elucidated. According to published research from France, "Dihydropteroate synthase gene (DHPS) mutations at...

C-type lectin DC-SIGN microdomains enable HIV entry.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- C-type lectin DC-SIGN microdomains act as portals for HIV entry. "The C-type lectin dendritic cell (DC)-specific intercellular adhesion molecule grabbing non-integrin (DC-SIGN; CD209) facilitates...

Pol incorporation into Gag VLPs is independent of upstream Gag domain.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Pol incorporation into Gag VLPs is independent of the upstream Gag-Pol Gag domain. "By using particle-associated reverse transcriptase (RT) activity as an assay for Pol incorporation into human...

Protease activity regulates Env-mediated membrane fusion.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- HIV protease activity regulates Env-mediated membrane fusion. Evidence has been presented "for a direct interaction between the matrix (MA) domain of the human immunodeficiency virus type 1 (HIV-1)...

Social networks and oral testing improve minority HIV screening rates.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- The use of social networks and oral testing can improve minority HIV screening rates. In a recent study, public health researchers in Massachusetts evaluated a program designed "to boost HIV testing...

Nucleocapsid-RNA interactions crucial for stability, but not assembly.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- HIV nucleocapsid-RNA interactions are crucial for structural stability, but not for viral assembly. According to published research from the United States, the "process of RNA incorporation into...

Internalization and recycling mechanisms of CCR5 clarified.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- The internalization and recycling mechanisms of CCR5 have been characterized. "CCR5 is a G protein-coupled receptor that binds several natural chemokines but it is also a coreceptor for the entry of...

Effects of indinavir on sterol, fatty acid homeostasis clarified.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- The effects of indinavir on sterol and fatty acid homeostasis have been characterized. "Human immunodeficiency virus protease inhibitors induce hyperlipidemia in many patients treated with these...

Houston firm set to begin human trials of new HIV treatment.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Stratus Research Labs will soon begin human trials in Latin America of its treatment, A-221-HIV, on patients infected with the HIV virus. Stratus is a privately held company with offices in Houston,...

Injection drug use attenuates HAART benefits.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Injection drug use attenuates the benefits of HAART. "There is evidence that HIV-positive injecting drug users benefit less than other risk groups from highly active antiretroviral therapy that has...

Lipid membranes likely involved in enfuvirtide activity.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Lipid membranes are likely involved in the antiretroviral activity of enfuvirtide. According to recent research from Portugal, "Partition of the intrinsically fluorescent HIV fusion inhibitor...

Methamphetamines augment HIV replication in humans.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Meth use augments HIV replication in humans. "Abuse of methamphetamine (METH) is a frequent comorbidity among individuals infected with human immunodeficiency virus (HIV) type 1," scientists in the...

T-20 cross-reactive gp41 antibody does not reduce T-20 efficacy.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Enfuvirtide cross-reactive gp41 antibody has no significant effect on the outcome of enfuvirtide treatment. In a recent study, scientists in Canada "investigated the effect of enfuvirtide...

Two-drug regimen can reduce vertical transmission risk to below 2%.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Data from the Perinatal HIV Transmission Trial group (PHPT), a collaboration of researchers from Thailand, France, and the U.S., show that a simple two-drug regimen can reduce the risk of...

Measles virus expressing HIV proteins induces antibodies to HIV.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- A single injection of recombinant measles virus vaccines expressing human immunodeficiency virus (HIV) type 1 clade B envelope glycoproteins induces neutralizing antibodies and cellular immune responses...

Hepatitis C virus infection raises the risk for oral squamous cell carcinoma.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus infection raises the risk for oral squamous cell carcinoma. "The most important complication of oral lichen planus (OLP) is the development of oral squamous cell carcinoma (OSCC)...

Phase I study to begin for therapeutic vaccine for hepatitis.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Genencor International, Inc., (GCOR) will begin phase I safety and immunogenicity testing for its DNA-based therapeutic vaccine to treat hepatitis B. Trials are scheduled to begin under an...

Cucumber mosaic virus as carrier of a hepatitis C virus-derived epitope.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- The cucumber mosaic virus can be used as a carrier of a hepatitis C virus-derived epitope. "Cucumber mosaic virus (CMV) is a three component isodiametric plant virus which is common worldwide and...

IL-23 induces strong immune responses in hepatitis C DNA immunization.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- IL-23 induces stronger sustained CTL and Th1 immune responses than does IL-12 after hepatitis C virus envelope protein 2 DNA immunization. "IL-23 is a heterodimeric cytokine consisting of p19 and...

Mild infection will rapidly worsen in one in three people affected.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Mild hepatitis C infection will rapidly worsen in one in three of those affected, suggests new research. This is particularly likely in those who are older when first infected, and those who already...

Adenovirus expressing papillomavirus E2 protein eliminates infection.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Vaccination of rabbits with an adenovirus vector expressing the papillomavirus E2 protein leads to clearance of papillomas and infection. "Cervical cancer arises from lesions caused by infection...

CIEF-WCID may enhance norovirus testing.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- A novel assay may enhance norovirus detection in food and clinical isolates. In a recent study from Canada, "A capillary isoelectric focusing-whole column imaging detection (CIEF-WCID) method was...

Varicella infections in pregnant women require expeditious management.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Varicella infections in pregnant women require expeditious management. According to recent research from France, "varicella during pregnancy is a rare occurrence because of a high rate of...

Road traffic exhaust might be involved in childhood leukemia.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Children with more exposure to motor vehicle emissions had higher incidences of leukemia, researchers say. According to a study from Italy, "To assess the effect of road traffic exhaust on the risk...

Late CMV PRP reported after stem-cell transplantation.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- An incidence of late CMV PRP has been reported in a stem-cell transplant recipient. In a case described by physicians in Germany, a "55-year-old man with acute myeloid leukemia in second relapse...

Truncated hepatitis B virus X gene sequences associate with liver cancer.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Truncated hepatitis B virus X gene sequences associate with liver cancer. "Although the integration of hepatitis B virus (HBV) into human DNA has been found to be associated with the development of...

5-Fluorocytosine increases the toxicity of oncolytic viruses.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- 5-Fluorocytosine increases the toxicity of oncolytic viruses. "Clinical studies with oncolytic adenoviruses have shown that existing viruses are safe but lack efficacy. To selectively increase the...

Patent granted for EradicAide technology to diagnose, prevent, treat AIDS.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Adventrx Pharmaceuticals (AVRX) announced that its collaborators at the University of Texas M.D. Anderson Cancer Center have been issued United States Patent number 6,656,471 entitled "HIV-specific...

HAART induces abnormal bone metabolism, reduces BMD in children.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- HAART causes abnormal bone metabolism and reduces BMD in children. According to recent research from Italy, "Highly active antiretroviral therapy (HAART) may be a contributory factor for a...

Production of drug-sensitive HIV continues in children during successful HAART.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- HIV production continues in HAART-treated children with undetectable viremia, although the evolution of drug resistance is halted in these patients. "Highly active antiretroviral therapy (HAART) can...

Biomedical company announces new member of board of directors.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Response Biomedical Corp. (RBM) announced the appointment of Stan Yakatan, chairman of U.S.-based Katan Associates International, to the company's board of directors. The company also announced...

Biotechnology company appoints new member to board of directors.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- VIRxSYS Corporation announced the appointment of John P. Phair, MD, professor emeritus of medicine, Northwestern University, Feinberg School of Medicine, to serve on its board of directors. Dr....

Pharmacokinetics of emtricitabine in HIV-infected children determined.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Investigators report the pharmacokinetics of emtricitabine in HIV-infected children in a recent issue of Antimicrobial Agents and Chemotherapy. "Emtricitabine (FTC; Emtriva), a potent deoxycytidine...

Advances in species barrier in human and animal prion diseases reviewed.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Researchers review the advances in research on the species barrier in human and animal prion diseases in a recent issue of the journal Medycyna Weterynaryjna. According to published research from...

Brazilian ex-soccer players may have spread hepatitis C with shared needles.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Brazilian ex-soccer players may have spread hepatitis C with shared needles. According to recent research from Brazil, "in order to evaluate the significance of injecting vitamins complexes and...

Respiratory syncytial virus protein linked to cell membrane of infected cells.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- The matrix protein of respiratory syncytial virus is associated with the host cell membrane of infected cells. "The matrix protein of paramyxoviruses plays an important role in virus assembly...

2003 Outbreak of severe acute respiratory syndrome in Beijing summarized.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Researchers have summarized the 2003 outbreak of severe acute respiratory syndrome in Beijing in the journal Emerging Infectious Diseases. According to recent research from the United States and...

SARS vaccine phase I clinical testing commences.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Sinovac Biotech Ltd. (SNVBF) announced that the Chinese State Drug Administration (SFDA) has authorized its operating subsidiary in Beijing, Sinovac Biotech Co., Ltd., to select 30 volunteers for the...

Bio-insecticide applications show promise in controlling West Nile virus.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Terra Nostra Technology Ltd. (TNRL) announced promising results obtained from laboratory efficiency trials conducted on its fungal bio-insecticide, Tolypocladium sp., for control and elimination of the...

WNV infection in kidney transplant recipient reported.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- The first known case of West Nile virus (WNV) infection associated with kidney transplantation has been reported. According to recent research from the United States, WNV, "a mosquito-transmitted...

Dengue virus strains show promise for candidate vaccines.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- Scientists have identified dengue virus strains that show promise for candidate vaccines. According to a study from the United States, "Dengue (DENV) virus strains for each of the four DENY...

Report finds inactivated influenza virus vaccines effective in children.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- Every winter inevitably brings with it the flu season, but kids don't inevitably have to contract the flu. A new report, which reviews the results of multiple studies on the effects of influenza vaccine...

Safe and immunogenic monovalent attenuated dengue vaccines developed.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- Phase 1 studies have revealed safe and immunogenic monovalent attenuated dengue vaccines. According to published research from the United States, "We describe the results of initial safety testing...

Altered iron associates with mutations in those with chronic hepatitis C.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- Altered iron stores associate with mutations in those with chronic hepatitis C. According to published research from Germany, "hepatitis C virus infection is often associated with an elevation of...

IL-2 expression during RSV infection improves memory CD8 T cell development.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- IL-2 expression during experimental respiratory syncytial virus infection improves effector activity and memory CD8 T cell development. According to recent research from South Korea and the United...

gp64-Pseudotyped vectors are appealing because of narrower cell attraction.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- gp64-Pseudotyped vectors are appealing because of narrower cell attraction. According to a study from the United States, "the envelope glycoprotein from vesicular stomatitis virus (VSV-G) has been...

Data presented on potential new class of antiretroviral therapy.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- Bristol-Myers Squibb Company (BMY) presented data from study AI430-003 on BMS-488043, one of the compounds from its series of experimental HIV-1 attachment inhibitors - a potential new class of...

Bird flu not going away soon, WHO says.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- Bird flu is not going away anytime soon, the World Health Organization said, as South Asian health officials agreed to cooperate in preventing the disease from spreading. The officials adopted a...

Expert warns bird flu outbreak could evolve into SARS-like epidemic.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- Health experts February 19, 2004, urged Asian countries to step up vigilance against bird flu amid worries it has the ability to evolve into a SARS-like human epidemic that killed hundreds last year....

Infection-control company launches fight against avian flu.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- JohnsonDiversey, Inc., is partnering with its customers across the globe to launch an offensive against the spread of avian flu. The effort includes offering products that are registered by the...

New approach may provide prompt recovery from bird flu.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- GenoMed, Inc., (GMED) announced that its treatment approach to viruses, which tones down the host's immune response rather than trying to kill the virus, should be effective against the bird flu. ...

New research could lead to potential treatment for avian flu.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- With the re-emergence of SARS and another outbreak of avian influenza in Asia, many government officials are concerned the outbreaks will increase and a new epidemic will emerge. In response to...

South Asia health officials hold emergency meeting on avian influenza.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- Preventing the spread of bird flu in highly populous South Asia was the focus of a meeting February 16, 2004, in New Delhi of health officials from seven countries in the region, officials said. ...

U.S. senators want task force to deal with avian flu.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- U.S. Senators Robert C. Byrd and Jay Rockefeller have asked the U.S. Department of Agriculture to take steps to ensure the health of West Virginia's poultry industry. Byrd and Rockefeller, both...

Hepatitis C virus relies on cellular proliferation for genomic replication.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus relies on cellular proliferation for genomic replication. "Considerable controversy surrounds the impact of hepatitis C virus (HCV) protein expression on viability of host cells...

Atypical glandular cells in HPV+ patients may indicate serious disease.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- Human papilloma virus (HPV)-positive atypical glandular cells (AGS) may be helpful in evaluating patients with atypical endocervical cells. According to recent research from the United States,...

Cervical cancer prevention should include human papillomavirus testing.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- Researchers recommend ways to incorporate human papilloma virus (HPV) testing into clinical practice. "A clear causal relationship has been established between human papilloma virus (HPV) infection...

Meta-analysis suggests HPV testing helps identify potential cases.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- A test for infection with human papillomavirus (HPV) can more accurately predict whether a woman with an equivocal cervical abnormality found on a Pap smear is likely to develop invasive cancer compared...

Study characterizes gene silencing in precursor to disease.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- Researchers in the Netherlands have characterized gene silencing in a precursor to cervical cancer. Infection with high-risk human papillomavirus (HPV) types causes cervical cancer, and genetic and...

Effectiveness of vaccine decreases after 1 year.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- The effectiveness of the chickenpox vaccine decreases significantly in the first year after vaccination, and also appears lower if the vaccine is administered to children younger than 15 months of age,...

Glycoprotein B DNA vaccine prevents congenital cytomegalovirus transmission.
March 9, 2004... 2004 MAR 9 - (NewsRx.com & NewsRx.net) -- Preconception vaccination with a glycoprotein B (GB) DNA vaccine protects against cytomegalovirus (CMV) transmission in the guinea pig model of congenital CMV infection. "DNA vaccines expressing...