Virus Weekly articles from March 2003

Virus Weekly archives from March 2003

Modified amplification refractory mutation system useful for measles, mumps virus genotyping.(Brief Article)
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- Researchers in England have developed a novel assay for genotyping measles and mumps viruses during outbreaks. This test is "based on a modification of the amplification refractory mutation system...

Researchers discover how virus spreads through the body.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- Researchers from Imperial College London, University of Oxford, Kagoshima University (Japan), and University of the Ryukyus (Japan) have discovered the mechanism by which human T-lymphotropic virus type...

Resistance to syncytia is due to viral protein's truncation.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- "Human T-cell leukemia virus (HTLV) envelope (Env) glycoproteins induce fusion, leading to rampant syncytium formation in a broad range of cell lines. Here, we identified murine, hamster, canine, and...

Nipah virus infection affects spinal cord, eyes.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- Researchers in Singapore have provided new insight into the effects of Nipah virus infection. "The Nipah virus is a newly identified paramyxovirus responsible for an outbreak of fatal encephalitis...

SV5 and HPIV2 interacting proteins reveal complex including STAT1, STAT2, DDB1.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- "Signal transducer and activator of transcription (STAT) proteins are normally long-lived, but infection with certain Paramyxoviruses results in efficient loss of IFN-responsive STAT1 or STAT2. ...

L protein is an oligomer with multiple independent domains.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- "The RNA-dependent RNA polymerase of Sendai virus consists of two subunits, the L and P proteins, where L is thought to be responsible for all the catalytic activities necessary for viral RNA synthesis....

Many promising new drugs on the horizon.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- A variety of highly effective new AIDS drugs are on the horizon, experts say, easing worries that the fast-mutating virus will outstrip doctors' ability to treat it. Ever since combinations of AIDS...

Resistance data on mutation patterns can help predict future options.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- The results from a longitudinal study of the relative frequency of various types of HIV mutations associated with the use of antiretroviral therapy (ART) were presented recently at a meeting of leading...

E3 promoter responds to activation signals in human T cells.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- According to a study in the United States, "The group C adenoviruses typically cause acute respiratory disease in young children. In addition, a persistent phase of infection has been observed in which...

IL-28, IL-29 are induced by virus and act through an IL-10 receptor.(Brief Article)
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- "Cytokines play a critical role in modulating the innate and adaptive immune systems. Here, we have identified from the human genomic sequence a family of three cytokines, designated interleukin 28A...

Three IFN-lambdas act through a distinct class II cytokine receptor complex.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- Recent research from the United States reports "the identification of a ligand-receptor system that, upon engagement, leads to the establishment of an antiviral state. Three closely positioned genes on...

Adeno-associated virus production is optimized in roller bottles.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "adeno-associated viral (AAV) vectors are used for in vivo gene transfer in a number of preclinical models of genetic diseases (including...

Evidence and an animal model for herpesvirus pathology are proposed.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- According to a study from Hungary, "The gamma-herpes virus bovine herpes virus type 4 (BoHV-4) is distributed worldwide in cattle populations, with unknown pathogenicity. Bovine endothelial cells were...

Papillomavirus' E6 and E7 proteins differentially protect from cell apoptosis.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "Cervical cancer cells express high risk human papillomavirus (HPV) E6 and E7 proteins, and repression of HPV gene expression causes the cells to...

IE1 binds to HDAC-2 to undo suppression of viral transcription and replication.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "Herpesviruses start their transcriptional cascade at nuclear domain 10 (ND10). The deposition of virus genomes at these nuclear sites occurs due to the...

EBI3 plays role in Th2-type immune responses induction, inflammation development.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "Epstein-Barr virus-induced gene 3 (EBI3) is a widely expressed IL-12p40-related protein that associates as a heterodimer with either IL-12p35 or an IL-12p35...

Lytic reactivation in infected B cells selectively arrests host functions.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- Researchers in Japan report that "Productive infection and replication of herpesviruses usually occurs in growth arrested cells, but there has been no direct evidence in the case of Epstein-Barr virus...

vIL-10 inhibition of antigen-presenting function may help in EBV immune evasion.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- According to recent research in the United States, "Monocytes and macrophages play a central role in viral infections, as a target for viruses and in activation of both innate and adaptive immune...

Multiple herpesvirus infections have limited effect on progression rate.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- "The effects of herpesviruses infection on the progression of HIV disease remain controversial, with some studies showing accelerated progression and others showing no effect," according to recent...

Cytomegalovirus infection may have protective effect.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- Cytomegalovirus infection may protect against HIV-induced neurological damage, researchers in France say. "Within the brain, glial cells are target cells for human cytomegalovirus (HCMV) and HIV,"...

Glucocorticoid treatment needed for patients with adrenal insufficiency.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- "In human immunodeficiency virus infected individuals, human cytomegalovirus (CMV) remains a significant pathogen," according to a recent study from New York University. "The adrenal gland is a...

Furin linked to the maturation of hepatitis B antigen.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- Medical investigators have suggested that furin may be associated with the maturation of the hepatitis B e antigen. According to a study from France, "the hepatitis B virus P22 protein is a...

ICP10 PK-induced activation of ERK pathway results in Bag-1 upregulation.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "Herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) can trigger or block apoptosis in a cell type-dependent manner. "We have recently shown...

CXCR2 homologue enhances reactivation from latency.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- "The open reading frame (ORF) 74 of gamma-2-herpesviruses encodes a G protein-coupled receptor which is highly conserved in members of this subfamily and is homologous to the CXCR2 chemokine receptor....

Human CMV UL97, an antiviral drug target, is required at nuclear egress.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "Human cytomegalovirus encodes an unusual protein kinase, UL97, that activates the established antiviral drug ganciclovir and is specifically...

Many transcriptional activators participate in HTLV-I transcription regulation.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- According to a study in the United States, "The human T-cell leukemia virus (HTLV-I)-encoded Tax protein is a potent transcriptional activator that stimulates expression of the integrated provirus. ...

Coagulation, fibrinolysis may not affect dengue-virus infection outcome.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- "Despite efforts to elucidate the pathogenesis of dengue fever, the progression into severe disease remains poorly understood," according to a recent study from the Netherlands. "In vitro findings...

Homologous antibodies may protect against Norwalk-like viruses.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- "Host immune responses to human caliciviruses are difficult to study because of the lack of a clear definition of antigenic or serological types," according to recent research from the United States....

Genetics of influenza viruses reviewed.(Brief Article)
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- According to a recent review from the United States and England, "Influenza A viruses contain genomes composed of eight separate segments of negative-sense RNA. Circulating human strains are notorious...

Genetically modified H5N1 influenza A virus vaccine candidate developed.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States and England, "Avian influenza A H5N1 viruses similar to those that infected humans in Hong Kong in 1997 continue to circulate in waterfowl and have...

Epstein-Barr virus' LMP1 has a TRAF binding domain; it can activate JNK.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- According to a study from England, "The oncogenic Epstein-Barr virus (EBV) encoded latent infection membrane protein 1 (LMP1) mimics a constitutive active tumor necrosis factor (TNF) family receptor in...

Prevailing genotype changes frequently in Osaka.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- The predominant genotype of measles virus (MV) changes regularly and relatively frequently in Osaka, Japan, researchers there say. The genotypes of a group of 44 MV strains isolated in Osaka between...

Slower nsP1 processing may contribute to adult S.A.AR86 phenotype.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- According to a study in the United States, "The Sindbis-group alphavirus S.A.AR86 encodes a threonine at nonstructural protein 1 (nsP1) 538 that is associated with neurovirulence in adult mice. ...

Viral load could be used as a marker for risk of cervical cancer.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- "HPV infections are believed to be a cause of cervical cancer. Viral burden, as a surrogate indicator for persistence, may help predict risk of subsequent SIL. We used results of Ill test and cytology...

Five dead as virus outbreak, panic grip southern China.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- An unidentified virus that causes pneumonia has killed 5 people and left about 300 hospitalized in southern China. Rumors of a surging death toll prompted frightened residents to stock up on...

Pathogenesis is reduced following combined antiviral/immunomodulatory treatment.(Brief Article)
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- Recent research from the United States reports "the responses of mice with symptomatic pneumovirus infection to combined antiviral and specific immunomodulatory agents. Mice infected with pneumonia...

Specific hepatitis C virus genotype more common among people with coinfection.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- People coinfected with SEN virus and hepatitis C virus (HCV) may be more likely to be infected with HCV genotype 2a, according to researchers in Taiwan. "To clarify the influence that a recently...

HHV-7 infection may raise HHV-6 reactivation risk.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- Human herpesvirus (HHV)-7 may help mediate Roseolovirus (HHV-6) reactivation after hematopoietic stem cell transplantation, researchers in France say. HHV-6 and -7 viremia was "evaluated...

Complement component 3 required for expansion of CD8 cells in viral infections.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "In addition to its established role in innate immune mechanisms, complement component C3 is also of critical importance in B cell activation and T...

Mature glycoprotein (gp)E, enabled by gpI, is required for infectivity.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "The glycoprotein E (gE) of varicella zoster virus (VZV), encoded by ORF68, is the most abundant viral glycoprotein. In the current experiments, we...

Cytokine involvement with memory T cells during viral infection reviewed.(Brief Article)
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- "Much progress has been made in understanding the relationship between cytokines, T cell development, and the maintenance of memory T cells by examining the immune response to respiratory viral...

Adenoviruses ideal for assessing angiogenic genes in assays.(Brief Article)
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- Adenoviruses are excellent vectors for exploring the influence of angiogenic genes in chick chorioallantoic membrane assays, researchers in Germany say. "The chicken chorioallantoic membrane CAM...

Hybrid adenoretroviral vector exhibits better integration efficiency.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- A hybrid adenoviral vector has demonstrated better integration efficiency, government researchers in the United States report. "The frequency with which the hybrid vector AdLTR-luc mediates genomic...

Transcriptional inactivation of amphotropic murine leukemia virus replication in human cells.(Brief Article)
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- "Amphotropic murine leukemia virus (MLV) replicates in cells from various mammalian species including humans and is a potential contaminant in MLV vector preparations for human gene transfer studies....

A waterborne outbreak of Norwalk-like virus occurs among in Wyoming.(Brief Article)
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- According to a recent report from the United States, "In February 2001, episodes of acute gastroenteritis were reported to the Wyoming Department of Health from persons who had recently vacationed at a...

Small interfering RNAs clear replicating hepatitis C virus in cell culture.
March 4, 2003... 2003 MAR 4 - (NewsRx.com & NewsRx.net) -- Silencing RNAs offer a way to diminish hepatitis C virus RNA expression, according to researchers in the United States. "RNA interference is a cellular process of gene silencing in which small...

Emory researchers identify link between lipid abnormalities and AIDS therapy.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- Researchers from Emory University and the Atlanta Veterans Affairs (VA) Medical Center have used a lipid biomarker called apolipoprotein C-III (ApoC-III) to help establish the relationship between HIV...

No evidence for immune system overload after triple jab MMR.(Brief Article)
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- There is no evidence that the triple MMR (measles, mumps, and rubella) vaccine causes immune system overload and makes children more vulnerable to serious bacterial infection, finds a new study. If...

Virus DNA can be found in sera of children with respiratory infection.(Brief Article)
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- "Serum samples from 68 immunocompetent infants (mean age, 12.6 mo) with an acute adenovirus infection of the respiratory tract (39 experiencing their first adenovirus infection) were tested for the...

CMV infection is risk factor that should be considered before treatment.(Brief Article)
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- According to a study from Switzerland, "This case report describes a 63 yr old woman with a 15 yr history of Crohn disease. After a severe relapse with colitis she was treated with immunosuppressive...

Nucleic acid amplification assays detect equine encephalitis viruses.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- Nucleic acid amplification assays have been developed to detect North American eastern and western equine encephalitis viruses. "We have developed nucleic acid sequence-based amplification...

Replication is inhibited inversely to NO production of target cells.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "Nitric oxide (NO) is generated by recruited inflammatory cells and by pulmonary epithelial cells in response to respiratory virus infection, although the...

Preliminary data from CONTEXT trial presented.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- Preliminary 24-week data were presented from the CONTEXT trial, an open-label, multicenter study evaluating the safety and efficacy of once-a-day (QD) or twice-a-day (BID) dosing of the investigational...

Study demonstrates comparable antiviral efficacy of HIV drugs.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- Results of the 2NN study show no statistical difference between Viramune (nevirapine, Boehringer Ingelheim) and efavirenz (Sustiva, Bristol Myers Squibb Co.) in anti-HIV efficacy with respect to viral...

Immune response cells within the liver constrain hepatitis C virus load.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - New research indicates cytotoxic T lymphocytes (CTLs) localized within the liver are responsible for limiting viral replication in patients infected with...

Glycoprotein blocks antigen presentation by retaining class I molecules in ER.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- According to a study from South Korea, "US3 of human cytomegalovirus is an endoplasmic reticulum resident transmembrane glycoprotein that binds to major histocompatibility complex class I molecules and...

Antigens and immunoevasins are opponents in cytomegalovirus immune surveillance.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- Antigens and immunoevasins act as opponents in cytomegalovirus immune surveillance. According to recent research from Germany, "CD8+ T cells are the main effector cells for the immune control of...

Freeze-thaw cycles do not hinder detection of measles, mumps, rubella antibodies.(Brief Article)
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- A series of freeze-thaw cycles do not hinder the detection of measles, mumps, or rubella antibodies. "We investigated the effect of multiple freeze-thaw cycles on mumps, measles, and rubella virus...

Nuclear antigen leader protein (EBNA-LP) may also regulate apoptosis.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- According to a study from Japan, "Epstein-Barr virus (EBV) nuclear antigen leader protein (EBNA-LP) plays a critical role in EBV induced transformation. An earlier report by Kawaguchi showed that...

The lectins DC-SIGN and DC-SIGNR bind virus glycoproteins avidly.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "Ebola virus exhibits a broad cellular tropism in vitro. In humans and animal models, virus is found in most tissues and organs during the latter stages of...

Two-day doubling time measured in an immunosuppressed transplant patient.(Brief Article)
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- According to recent research from Italy, "The kinetics of Epstein-Barr virus (EBV) load was measured in peripheral blood mononuclear cells of a severely immunocompromised allogeneic bone marrow...

H. pylori CagA translocates into cells, binding SHP-2 in gastric mucosa.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- According to research from Japan, "Recent experiments have indicated that CagA of Helicobacter pylori is injected into epithelial cells via the type IV secretion system and undergoes tyrosine...

Gammadelta T cells cytotoxic to healthy T cells during infection.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- Gammadelta T cells become cytotoxic to healthy T cells during HIV infection. HIV disease progression in humans "is marked by declining CD4+ T-cell counts and increasing virus load (VL)," explained...

48-Week resistance data presented.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- Forty-eight week data were presented from two phase III studies (NEAT and SOLO) of treatment-naive patients with HIV infection, evaluating the resistance profile of the investigational protease...

Atazanavir may lead to increased viral susceptibility to other PIs.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- Bristol-Myers Squibb Co. (BMY) presented resistance data at a medical meeting in Boston from several phase II and phase III studies of atazanavir, an investigational protease inhibitor (PI) under...

Transgenic tobacco plants carry gene for hepatitis B virus surface antigen.(Brief Article)
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- Transgenic tobacco plants can carry the gene for hepatitis B virus surface antigen. According to recent research from Russia, "the plasmids carrying the gene encoding the hepatitis B surface...

Hepatitis C virus can infect and replicate in B cell lymphoma cell lines.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus can infect and replicate in B cell lymphoma cell lines. According to recent research from the United States, "hepatitis C virus (HCV) is a major cause of chronic hepatitis, liver...

Interferon treatment in chronic hepatitis C modulates thyroid autoimmunity.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- Interferon treatment in chronic hepatitis C modulates thyroid autoimmunity. According to a study from Italy, "interferon-alpha (IFN-alpha) treatment for chronic hepatitis C (CHC) has been...

Review covers recent progress in herpes simplex virus vaccine research.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- Recent progress in herpes simplex virus vaccine research has been been reviewed recently. According to researchers from the United States, "Herpes simplex virus types 1 and 2 (HSV-1 and HSV-2)...

Outbreaks in Africa underscore urgency for increased global surveillance.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- As the world's influenza experts gathered recently in Geneva to determine next year's vaccine composition, recent outbreaks in the Democratic Republic of the Congo and in Madagascar illustrate the...

Positive results from FluINsure challenge study announced.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- ID Biomedical announced that preliminary data from the most recent clinical study of its FluINsure intranasal, non-live, influenza vaccine showed positive results with respect to both the safety and...

New influenza vaccination recommendations issued for children and pregnant women.(Brief Article)
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- New recommendations for influenza vaccination for children and pregnant women have been issued recently. According to a recent report from the United States, "This year the Advisory Committee on...

Recognizing influenza may be difficult in older patients with COPD.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- Recognizing influenza in older patients with chronic obstructive pulmonary disease (COPD) can be difficult. According to a study from the United States, "A substudy analysis was conducted to...

A chronic Epstein-Barr virus infection can cause neuropathy and skin erythema.(Brief Article)
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- Researchers from Japan reported "a patient with leukocytoclastic-vasculitic neuropathy associated with chronic Epstein-Barr virus (EBV) infection. A 55 year old man had been suffering from chronic...

Association found between class I HLA-B alleles and antibody levels.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- An association between class IHLA alleles and antibody levels was found after a single dose of measles vaccine. According to recent research from the United States, "Despite the success of the...

EBV's LMP-1 has high prevalence of 30-bp deletion and Xho1 polymorphisms.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- According to recent research from Malaysia, "Nasopharyngeal carcinoma (NPC), a malignancy associated closely with Epstein-Barr virus (EBV), is prevalent among Chinese of Southern China origin....

Epidemiology in Hong Kong shows general reduction as well as sex differences.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- "Epidemiologic data from the Hong Kong Cancer Registry for the period 1980-99 were analyzed. Altogether, 21768 new cases of nasopharyngeal carcinoma (NPC) and 8664 related deaths were registered. In...

HPV evades innate immunity by blocking interferon and immune activation.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "HPV infections of the epidermis and anogenital tract occur frequently in healthy individuals, and high risk HPV types are a major risk factor for cervical...

Molecular assays can detect newly identified human metapneumovirus.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- Molecular assays can detect the newly identified human metapneumovirus. "The recent description of the respiratory pathogen human metapneumovirus (hMPV) has highlighted a deficiency in current...

Early myeloblasts express parvovirus B19 receptor.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- Early myeloblasts express the parvovirus B19 receptor. According to a study from the United States, "glycosphingolipids (GSLs) are complex macromolecules on cell membranes that have been shown to...

CNS may be cytomegalovirus sanctuary.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- The central nervous system may act as a cytomegalovirus sanctuary in stem cell graft recipients. "Preemptive ganciclovir therapy has reduced the occurrence of early cytomegalovirus (CMV) disease...

Invasiveness is caused by low antibody titer to capsular polysaccaride.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- According to recent research from Germany, "The immune response to pneumococcal capsular polysaccharides (CPSs) and to the pneumococcal surface protein's cell wall associated serine proteinase A...

New expression vector based on pseudorabies virus amplicons has potential.(Brief Article)
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- A new expression vector based on pseudorabies virus amplicons has shown significant potential. According to a study from Spain, "pseudorabies virus (PrV), a herpesvirus from the Alphaherpesvirinae...

Distinct effectors are responsible for viral persistence in nervous system.
March 11, 2003... 2003 MAR 11 - (NewsRx.com & NewsRx.net) -- Distinct effectors are responsible for viral persistence in the nervous system. According to recent research from the United States, "central nervous system infection by the neurotropic JHM strain...