Virus Weekly articles from June 2004

Virus Weekly archives from June 2004

High viral loads and diverse viremia characterize pediatric HCV infection.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- High viral loads and diverse viremia characterize pediatric HCV infection. "Hepatitis C virus (HCV) infection is uncommon in children, and its natural history is still unknown." The aim of this...

HSV-1 gingivostomatitis in last 2 trimesters of pregnancy doesn't harm fetus.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- A study from Israel reassures that primary herpes simplex virus type 1 gingivostomatitis occurring in women in the last two trimesters of pregnancy doesn't appear to cause problems for the fetus. ...

Murine herpesvirus-68 ORF73 critical for latency establishment and maintenance.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Murine herpesvirus-68 ORF73 is critical for latency establishment and maintenance. "In vitro studies have established that the latency-associated nuclear antigen encoded by human Kaposi's...

B7[superscript]+CTLA4[superscript]+ T cells engage in T-T cell interactions that mediate apoptosis.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- B7[superscript]+CTLA4[superscript]+ T cells engage in T-T cell interactions that mediate apoptosis. "Apoptosis in lymph node (LN) T cells of feline immunodeficiency virus (FIV)-infected cats is...

BK virus load correlates with clinical course of infection in renal transplants.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- BK virus load correlates with clinical course of infection in renal transplant patients. Scientists writing in the Journal of Clinical Microbiology wrote, "BK virus-allograft nephropathy (BKVAN) is...

Wild-type CCR5 confers HIV-1 cross-clade resistance.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Scientists describe risk associated HIV-1 cross-clade resistance of whole peripheral blood mononuclear cells from exposed uninfected individuals with wild-type CCR5. According to a study from the...

Maternal malaria and perinatal HIV transmission interaction complicated.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- The interaction between maternal malaria infection and perinatal HIV transmission is complicated. According to recent research from an international team of scientists, "To determine whether...

CTL ontogeny and viral escape have implications for HIV vaccine design.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Cytotoxic T lymphocyte (CTL) ontogeny and viral escape have implications for HIV vaccine design. According to recent research published in the journal Trends in Immunology, "The protective role of...

Components of HIV vaccine are recognized by T-helper cells.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Minor components of a multi-envelope HIV vaccine are recognized by type-specific T-helper cells. "HIV has thus far evaded control by vaccines, in part due to the high diversity among viral...

IL-15 may be beneficial for AIDS immunotherapy.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Interleukin-15 (IL-15) may be beneficial for AIDS immunotherapy. According to recent research published in the journal Trends in Immunology, "The current antiretroviral therapy has improved the...

Neutralizing antibodies against HIV-1 tat antigen characterized.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Scientists have characterized neutralizing human monoclonal antibodies against human immunodeficiency virus type 1 tat antigen. According to a study from France, "The human immunodeficiency virus...

Role of therapeutic vaccines for the control of HIV-1 reviewed.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Scientists review the role of therapeutic vaccines for the control of HIV-1 in a recent issue of the Journal of Antimicrobial Chemotherapy. According to recent research from England, "The recent...

Virus-like particles rich in HIV-1 envelope gp120 developed.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Researchers have developed virus-like particles rich in HIV-1 envelope gp120. "In order to improve the immunogenicity of HIV-1 envelope glycoproteins, we have fused gp120 to a carrier protein,...

Avian influenza may be new pandemic threat.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Avian influenza may be a new pandemic threat. According to a study from the United States, "In December 2003, the largest outbreak of highly pathogenic avian influenza H5N1 occurred among poultry...

New strain of bird flu found in Fraser Valley; school closed.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- A new strain of bird flu has been found in the Fraser Valley, different from anything seen in the area before, officials said. Scientists can't rule out the possibility the strain is the one...

Blood donors in Lagos, Nigeria, misinformed regarding safety of donating blood.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Blood donors in Lagos, Nigeria are misinformed regarding the safety of donating blood. "A total of 542 blood donors from Lagos State University Teaching Hospital (Lasuth), Ikeja, were interviewed...

Vaccination against cervical cancer reviewed.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Scientists review vaccines against cervical cancer in a recent issue of Hospital Medicine. According to recent research from Wales, "The link between human papillomavirus (HPV) and cervical cancer...

Phase III Ampligen trial meets primary endpoint for CFS.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Hemispherx Biopharma, Inc., (HEB) announced that its pivotal phase III chronic fatigue syndrome (CFS) trial of Ampligen met its primary endpoint with patients receiving Ampligen for 40 weeks. A...

Good management of hepatitis C requires thorough pretreatment evaluation.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Good management of hepatitis C requires thorough pretreatment evaluation. "Chronic hepatitis C virus infection is a common and serious disease. Although an estimated 2.7 million persons in the...

Cytomegalovirus glycoprotein elicits antibody response in macaques.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Rhesus cytomegalovirus glycoprotein B elicits an antibody response in naturally infected rhesus macaques. "Rhesus cytomegalovirus (RhCMV) exhibits strong parallels with human CMV (HCMV) in terms of...

Dendritic cell vaccine efficacy quantified using flow cytometry.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- The protective efficacy of dendritic cell based vaccines in a human papillomavirus type 16 murine challenge model was quantified using flow cytometry. According to recent research published in the...

Vaccine-derived poliovirus isolated from stream waters in Hispaniola.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Circulating type 1 vaccine-derived poliovirus was isolated from sewage and stream waters in Hispaniola. "Twenty-one cases of acute flaccid paralysis (AFP) were reported on the island of Hispaniola...

EBV nuclear antigen leader protein induces B-cell TARC expression.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- The Epstein-Barr virus nuclear antigen leader protein (EBNA-LP) induces TARC expression by B cells. The EBNA-LP "plays a critical role in transformation of primary B lymphocytes to continuously...

Actimmune maker reports reduced net losses during first quarter.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- InterMune, Inc., (ITMN) announced results from operations for the first quarter ended March 31, 2004. The company recorded a net loss for the first quarter of 2004 of $11.7 million, or $0.37 per...

In vivo gene delivery with regulatable lentivirus surveys neurogenic function.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- In vivo gene delivery with regulatable lentivirus surveys neurogenic function. "CD81, a tetraspanin transmembrane protein involved in cell adhesion, is up-regulated in the mesolimbic dopaminergic...

Cost-effectiveness analyses needed to evaluate HIV/AIDS prevention and care.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- More cost-effectiveness analyses is needed to evaluate HIV/AIDS prevention and care. "As more effective HIV therapies have become available, resource constraints and cost-effectiveness have...

HIV-1 viral load increase confers virus escape risk via recombination diversity.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- HIV-1 viral load increase confers a risk of virus escape via recombination diversity. "Genetic recombination is believed to assist HIV-1 diversification and escape from host immunity and antiviral...

ReceptoPharm completes HIV in-vitro studies at two universities.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Nutra Pharma Corp. (NPHC), a biotechnology holding company, announced that its minority owned subsidiary, ReceptoPharm, Inc., has achieved a milestone in investigating their lead drug compound's effects...

STD/HIV prevalence higher in men presenting at STD clinic compared to gay cohort.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- STD/HIV prevalence is higher in men presenting at an STD clinic compared to a gay cohort. "This study was performed to investigate whether men who have sex with men visiting the sexually transmitted...

V82F/184V mutation decreases binding affinity of HIV-1 protease inhibitors.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- V82F/184V mutation decreases the binding affinity of HIV-1 protease inhibitors. "The protease from type I human immunodeficiency virus (HIV-1) is a critical drug target against which many...

Education, age, and drinking associated with smoking status in HIV/AIDS.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Education, age, and drinking are associated with smoking status in an HIV/AIDS population. "The aim of this study was to describe smoking prevalence and smoking behavior in a multiethnic low-income...

HIV prevalence highest in teenage pregnancy compared with older pregnant women.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- HIV prevalence is highest in teenage pregnancy compared with older pregnant women. "National HIV prevalence rate is derived from the sentinel surveys, which are carried out once in two years and...

Amino acid variation and HIV-1 gp120 evolution linked with second receptor usage.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Amino acid variation and HIV-1 gp120 evolution are linked with usage of the second receptor. "To clarify the relationship between the amino acid variations of the gp120 of human immunodeficiency...

IKK2 inhibitor alleviates kidney and wasting diseases in murine AIDS model.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- IKK2 inhibitor alleviates kidney and wasting diseases in a murine human AIDS model. "Wasting and renal diseases are frequent complications of HIV (human immunodeficiency virus) infection and are...

RH116 differentially regulates cell growth, death and HIV-1 replication.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- RH116 differentially regulates cell growth, programmed cell death and HIV-1 replication. "In an effort to define novel cellular factors regulating human immunodeficiency virus type 1 (HIV-1)...

Knowledge of HIV postexposure prophylaxis lacking.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Knowledge of HIV postexposure prophylaxis is lacking. "Since 1998, French HIV guidelines have recommended use of HIV prophylaxis after unprotected sex (post-exposure prophylaxis, or PEP) with an...

Deep salvage with amprenavir and lopinavir/ritonavir partially effective.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Deep salvage with amprenavir and lopinavir/ritonavir is partially effective. "The safety, efficacy, and mutual interactions of combination amprenavir with lopinavir/ritonavir as deep salvage...

HLA-B*5701 and Hsp70-Hom M493T alleles necessary for abacavir hypersensitivity.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- HLA-B*5701 and Hsp70-Hom M493T alleles are necessary for development of abacavir hypersensitivity in HIV-1-infected patients. According to research in Australia, "Susceptibility to a clinically...

A new system shows adenoviruses elicit poor transduction in esophageal cancer.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- A new system shows adenoviruses elicit poor transduction in esophageal cancer. According to a study from the Netherlands, "adenoviral gene therapy might be a promising therapeutic strategy for...

Crimean-Congo hemorrhagic fever virus genome L RNA segment sequenced.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Scientists have determined the sequence of the Crimean-Congo hemorrhagic fever virus genome L RNA segment and encoded protein. "Sequence analysis of the L RNA genome segment and predicted encoded L...

Molecular epidemiology of hepatitis B and C infections in Asia reviewed.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Researchers review the molecular epidemiology of hepatitis B and C virus infections in Asia in a recent issue of Pediatrics International. "The present paper provides a review of the current...

Site provides information about hepatitis infection and therapy.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Researchers have developed an Internet site (Hep-Net) to provide information about hepatitis infection and therapy. "In Germany almost 1 million people are affected by chronic viral hepatitis....

Risk factors for hepatitis C in Alaska natives reported.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Researchers report the epidemiology and risk factors for hepatitis C in Alaska natives in a recent issue of the journal Hepatology. According to scientists in the United States, "Large cohorts of...

Immune responses in patients with hepatitis C and HIV described.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Scientists describe virus dynamics and immune responses during treatment in patients co-infected with hepatitis C and HIV. According to a study from the United States, "Mathematical modeling of the...

HCV compartmentalization in circulating B cells and monocytes is common.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- HCV compartmentalization in circulating B cells and monocytes is common. "Differences in the composition of the hepatitis C virus (HCV) quasispecies between plasma and blood mononuclear cells (BMC)...

MMF does not decrease viral load in chronic HCV liver transplant recipients.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Mycophenolate Mofetil does not decrease viral load in chronic hepatitis C virus liver transplant recipients. "It has been suggested that Mycophenolate Mofetil (MMF) may have an antiviral effect in...

Chronic liver disease mortality in the United States reported.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Researchers report the prevalence of chronic liver disease mortality in the United States in a recent issue of the journal Hepatology. "In 1998, chronic liver disease (CLD) was the tenth leading...

Human herpesvirus-8 oral shedding higher without antiretroviral therapy.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Human herpesvirus-8 oral shedding is higher among HIV-infected men who are not receiving highly active antiretroviral therapy than among those receiving therapy. "Human herpesvirus-8 (HHV-8) is...

Interferon and immune cell interactions in HSV-1 infection characterized.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- The interactions between interferons and immune cells during HSV-1 infection have been characterized. In a recent study from Switzerland, the "essential components of the immune system that control...

Vaccinia virus encoding T-cell chemoattractant is attenuated in vivo.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- A recombinant vaccinia virus encoding the interferon-inducible T-cell alpha chemoattractant is attenuated in vivo. According to recent research from Australia, "Murine interferon-inducible T-cell...

DNA vaccine offers protection against infectious bursal disease virus.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- DNA-mediated vaccination with the VP2 capsid protein and chicken IL-2 genes provided partial protection against infectious bursal disease virus. "Several DNA vaccination experiments were performed...

Pandemic influenza can be contained with antiviral agents.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Pandemic influenza can be contained with antiviral agents. According to recent research published in the American Journal of Epidemiology, "For the first wave of pandemic influenza or a...

Guillain-Barre coexists with pericarditis after influenza vaccination.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Guillain-Barre syndrome can coexist with pericarditis or nephrotic syndrome after influenza vaccination. According to a study from Taiwan, "A 68-year-old woman and a 72-year-old man presented with...

Intranasal influenza vaccine causes facial paralysis.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- The intranasal influenza vaccine caused facial paralysis in a working population in Switzerland. According to recent research from Switzerland, "In the present study, we assessed the incidence of...

Trivalent inactivated influenza vaccine in young children reviewed.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Researchers review the safety and efficacy of trivalent inactivated influenza vaccine in young children in a recent issue of the Pediatric Infectious Disease Journal. "Increasing use of influenza...

MEK inhibition impairs influenza virus without emergence of resistance.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- MEK inhibition impairs influenza B virus propagation without emergence of resistant variants. "Influenza A and B viruses are still a major worldwide threat. We demonstrate that influenza B virus...

Most hepatocellular carcinoma in West Africa caused by hepatitis B.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Most cases of hepatocellular carcinoma in West Africa are caused by infection with hepatitis B virus. According to an international team of researchers, "Hepatocellular carcinoma (HCC) is the most...

Human metapneumovirus infection similar in severity to RSV in children.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Human metapneumovirus infection is similar in severity to respiratory syncytial virus (RSV) among children hospitalized with acute respiratory illness. According to published research from the...

Norovirus virus-like particles induce specific immune responses.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Recombinant virus-like particles of a norovirus (Genogroup II strain) administered intranasally and orally with mucosal adjuvants LT and LT(R192G) in BALB/c mice induce specific humoral and cellular...

Bovine parainfluenza virus type 3 vaccine shows promise in monkeys.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Bovine parainfluenza virus type 3 (PIV-3) vaccine shows promise in studies in rhesus monkeys. According to recent research published in the Journal of General Virology, "Restricted replication in...

Patent granted for CMX001, an orally-active smallpox therapeutic.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Chimerix, Inc., and the University of California, San Diego (UCSD) announced the issuance of U.S. Patent No. 6,716,825 entitled "Phosphonate Compounds" by the U.S. Patent and Trademark Office. The...

Antigens of abnormal isoform of prion protein characterized.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Researchers characterized the antigens of an abnormal isoform of prion protein using a new diverse panel of monoclonal antibodies. "We established a panel of monoclonal antibodies (mAbs) against...

Prion diseases provide insights on brain targeting.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Information gained from studying prion diseases has led to insights about brain targeting through the autonomous nervous system. According to a study from France, "The human central nervous system...

Prnp transfection suppress CVB3 replication in prion protein gene-deficient cell.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Prnp transfection suppresses CVB3 replication in prion protein gene-deficient cells. "The susceptibility of prion protein gene (Prnp)-null cells to coxsackievirus B3 (CVB3) was investigated. Primary...

PTEN transfection sensitizes prostate cancer cells to radiation therapy.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- PTEN transfection sensitizes prostate cancer cells to radiation therapy. "Bcl-2 is associated with resistance to radiotherapy in prostate cancer. It was recently demonstrated that transduction of...

Yaba-like disease virus protein is cell-surface receptor for chemokine.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Yaba-like disease virus protein 7L is a cell-surface receptor for chemokine CCL1. According to a study from England, "Yaba-like disease virus (YLDV) genes 7L and 145R are located on opposite ends of...

Close association between immune response and SIV encephalitis in macaques.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- There is a close association between immune response and SIV encephalitis in macaques. "Infection of pig-tailed macaques with the simian immunodeficiency virus (SIV) isolate SIVsmmFGb frequently...

HTLV-1 Tax directly transactivates immediately-early gene ETR101.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- HTLV-1 Tax directly transactivates the immediately-early gene ETR101. "Human T-cell leukemia virus type I (HTLV-I) Tax regulates viral and cellular gene expression through interactions with multiple...

Human T-lymphotropic virus type 1 can spread directly between lymphocytes.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Human T-lymphotropic virus type 1 can spread directly between lymphocytes. "Human T-lymphotropic virus type 1 (HTLV-1) varies little in sequence compared with human immunodeficiency virus type 1...

Rubella in developing countries still causing blindness and deafness.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Rubella in developing countries continues to cause blindness and deafness. According to a study from England, "Maternal rubella is now rare in many developed countries that have rubella vaccination...

Fear of SARS had strong impact on access to health care.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- A fear of SARS had a strong impact on access to healthcare. "Using interrupted time-series analysis and National Health Insurance data between January 2000 and August 2003, this study assessed the...

DNA vaccine induces SARS coronavirus protective immunity in mice.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice. "Public health measures have successfully identified and contained outbreaks of the severe acute respiratory...

Passive transfer of antibody prevents SARS replication.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Prior infection and passive transfer of neutralizing antibody prevent replication of severe acute respiratory syndrome coronavirus in the respiratory tract of mice. According to a study from the...

Method developed to monitor immune response against vaccinia virus.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Scientists have developed a high-throughput method to monitor the humoral immune response against vaccinia virus. According to published research from Germany and Sweden, "Vaccination against...

Prevalence of dermatologic reactions to smallpox vaccine reported.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Researchers report the prevalence of benign dermatologic reactions to smallpox vaccination in adults in a recent issue of Clinical Infectious Diseases. "A phase 1 smallpox vaccine trial involving...

GVHD associated with lower relapse after ALL hematopoietic stem cell transplant.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Graft-versus-host disease is associated with lower relapse after hematopoietic stem cell transplantation in acute lymphoblastic leukemia patients. "To determine the graft-versus-leukemia effect...

T cell immunity achieved using transgenic B lymphocytes.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- T cell immunity was achieved using transgenic B lymphocytes. "Adaptive immunity exists in all vertebrates and plays a defense role against microbial pathogens and tumors. T cell responses begin...

Smallpox vaccine might benefit those who can't use other vaccines.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Researchers at Saint Louis University are testing a smallpox vaccine that could be useful for people who are HIV-positive, undergoing chemotherapy or otherwise unable to use the existing vaccine,...

Carrier cells mediate the transfer of oncolytic parvovirus to metastatic tumors.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Carrier cells mediate the transfer of oncolytic parvovirus to metastatic tumors. According to a study from Germany, "over the last few years, naturally occurring or genetically manipulated oncolytic...

The DF3/MUC1 promoter gives oncolytic virus a boost.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- The DF3/MUC1 promoter gives oncolytic virus a boost. According to a study from the United States, "replication-conditional viruses destroy tumors in a process referred to as viral oncolysis. An...

Dual HHV8 and HCV infection induced Kaposi sarcoma in a female patient.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Dual HHV8 and HCV infection induced Kaposi sarcoma in a female patient. "Iatrogenic Kaposi's sarcoma develops in patients undergoing immunosuppressive treatment and is considered to be induced by...

Health officials fear complacency as another bout with West Nile begins.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Health officials are nearly as worried about complacency as mosquitoes, heading into Illinois' fourth summer of the deadly West Nile virus. An outbreak in 2002 infected 884 people, including 66...

Wild-type yellow fever virus linked to 17DD vaccine characterized.
June 1, 2004... 2004 JUN 1 - (NewsRx.com & NewsRx.net) -- Researchers have characterized a wild-type yellow fever virus in cases temporally associated with 17DD vaccination during an outbreak of yellow fever in Brazil. "A mass vaccination was carried out...

A new rapid molecular assay detects at least four strains of the SEN virus.
June 8, 2004... 2004 JUN 8 - (NewsRx.com & NewsRx.net) -- A new rapid molecular assay detects at least four strains of the SEN virus. "SEN viruses (SENV) are newly discovered blood-borne single-stranded circular DNA viruses that may play a role in liver...