Virus Weekly articles from June 2003

Virus Weekly archives from June 2003

Study finds portion of population resistant to infectious Norwalk virus.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Noroviruses, which have been especially problematic in the cruise industry in recent years, cause digestive tract infection or irritation resulting in an estimated 23 million infections, 50,000...

Enterotoxin adjuvant protects mice against respiratory syncytial virus.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Immunization onto shaved skin with a bacterial enterotoxin adjuvant protected mice against respiratory syncytial virus. "This study evaluated the potential of the skin as a non invasive route for...

TAR RNA adaptable for metal ion entry.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- HIV TAR RNA can interact with a wide variety of metal ions. According to recent research from the United States, "metal ion-induced changes in HIV-1 TAR RNA internal dynamics were determined by the...

Strong association seen between penile SCC and the presence of HPV DNA.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- There is a strong association between penile SCC and the presence of HPV DNA. According to published research from France, "Human papillomaviruses (HPV) are thought to be involved in penile squamous...

Gene coexpression in hepatocytes alleviates the possibility of cytotoxicity.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Gene coexpression in hepatocytes alleviates the possibility of cytotoxicity. "Replication-deficient adenovirus (Ad vector) is one of the most effective gene transfer systems. However, its employment...

Hepatitis C virus IRES facilitates protein synthesis in tumor vessels.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus IRES facilitates protein synthesis in tumor vessels. According to a study from Japan, "the development of gene delivery systems for therapeutic use involves vectors (often...

Lymphoproliferative disorder can have EBV infection in both B and T cells.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Lymphoproliferative disorder having EBV infection in both B and T cells can occur as a result of bone marrow transplant. "Post-transplantation lymphoproliferative disorder (PTLD) is usually an...

Vaccine producer provides updates on corporate programs.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Acambis plc (ACAM) announced its results for the first quarter ended 31 March 2003. During the first quarter of 2003, there were a number of positive developments relating to our smallpox vaccine...

Virion core structure elucidated.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- The structure of the HIV virion core has been elucidated. "Mature, infectious HIV-1 particles contain a characteristic cone-shaped core that encases the viral RNA and replication proteins,"...

Distinguishing virus-specific T cells can be done with peptide-HLA-GFP complexes.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Circulating HTLV-I specific T cells can be identified by uptake of peptide-HLA-green fluorescent protein complexes. According to recent research from the United States, "Antigen-specific CD8+ T...

Data presented on next CoVal fusion in pipeline targeting HBV.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Stressgen Biotechnologies Corp. (SSB) presented its latest preclinical research results at the 6th annual Conference on Vaccine Research on its new CoVal fusion compound, HspBcor, designed to treat...

Antigen-specific T cells and memory cells have alternate roles in HBV activity.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Antigen-specific T cells and memory cells have alternate roles in HBV activity. "We analyzed the prevalence and longitudinal fluctuation of hepatitis B virus (HBV)-specific CD8 T cells in chronic...

RNA aptamers inhibit HCVNS3 protease.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- RNA aptamers inhibit HCVNS3 protease. "Non-structural protein 3 (NS3) of hepatitis C virus (HCV) has two distinct activities, protease and helicase, which are essential for HCV proliferation. In...

Cloned hepatitis delta virus genotype IIb thrives in cell cultures.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Cloned hepatitis delta virus genotype IIb thrives in cell cultures. According to recent research published in the journal Biochemical and Biophysical Research Communications, "analysis of hepatitis...

Counteracting loops explain immune response to hepatitis C virus infection.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Counteracting loops explain immune response to hepatitis C virus infection. According to published research from England, "Cellular immune responses play an important role in the control of...

Experts examine global progress in vaccines.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Many of the world's vaccine scientists met at the National Foundation for Infectious Diseases' (NFID) Sixth Annual Conference on Vaccine Research to present the latest research on vaccines against...

Imported oysters may spread Norwalk-like viruses in Switzerland.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Oysters imported into Switzerland may carry Norwalk-like viruses. "Molluscan shellfish are known to be carriers of viral and bacterial pathogens," microbiologists there noted. "The consumption of...

Novel molecular assay detects low levels of Norwalk-like viruses.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- A novel molecular assay can detect low levels of Norwalk-like viruses (NLVs). The reverse transcription polymerase chain reaction (RT-PCR)-based test "is highly sensitive to a broad range of NLVs,"...

Nasal vaccine delivery platform data presented at vaccine conference.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Carrington Laboratories, Inc., (CARN) announced that results of an initial study sponsored by its subsidiary DelSite Biotechnologies, Inc., were presented at the 6th Annual Conference of Vaccine...

Immunity to influenza boosted by H5N3 A/Duck/Singapore/97 vaccine.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Immunity to influenza H5N1 was boosted by using an MF59-adjuvanted H5N3 A/Duck/Singapore/97 vaccine in humans. "In 1997, influenza A/Hong Kong/97 (H5N1) emerged as a potential human threat. In...

Mannose-binding lectin mutation is linked with cardiovascular lesions in babies.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- In children "Kawasaki disease is an acute vasculitis of possible infectious cause, which in particular affects the coronary arteries. Young children rely mostly on their innate immune system for...

SARS pathogen detection, resequencing array released.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Affymetrix, Inc., (AFFX) announced it is taking orders for its new GeneChip brand CustomSeq SARS Pathogen Detection Resequencing Array, designed to enable scientists to rapidly resequence different...

Immune cells may help deliver cancer vaccines for children.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- In a finding that could lay the groundwork for future cancer vaccines for children, cancer researchers working in cell culture have shown that modified immune cells can efficiently deliver genetic...

Recombinant adeno-associated viruses effect hippocampal gene transfer.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Recombinant adeno-associated viruses effect hippocampal gene transfer. "Genetic modification of the gerbil hippocampal neuronal cells in vivo helps us understand the mechanisms of neuronal function...

Virus-specific CD8 cell function often impaired in young children.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- HIV-specific cytotoxic T-cell function is often impaired in young seropositive children with low CD4 cell counts. "The immunology of vertical HIV transmission differs from that of adult infection...

New data released on plague, strep vaccines.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- ID Biomedical has confirmed that nasal Proteosome-based vaccines protect against pneumonic Plague caused by lethal aerosol infection with virulent Plague bacteria in a mouse model of airborne...

Pretreatment drug for RSV-related wheezing also effective after symptoms set in.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Infectious disease specialists at the University at Buffalo have demonstrated a potentially effective treatment to prevent the frequently life-threatening complications that can develop in infants from...

Antiviral medicine sent to Chinese Hospitals for testing.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Randy Powers, president of Liddell Laboratories announced that the first shipment of its new antiviral medicine designed for SARS patients will arrive in China and Hong Kong this week for clinical...

China broadens usage of i-STAT system.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- i-STAT Corporation (STAT), a manufacturer of point-of-care diagnostic systems for blood analysis, announced it is making stepped-up shipments of the i-STAT System to China. The shipments are part...

Expert says treatment for slowing AIDS virus might help.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- The SARS virus apparently attacks people's cells in a manner similar to the AIDS virus, which may offer clues for finding the best drugs to treat the newly discovered disease, an AIDS researcher says....

Expert: Virus may mutate profoundly.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- The SARS virus does not appear to have mutated significantly in the weeks since it spread from Asia, but a leading expert says the virus still could evolve into a more dangerous form if it enters a race...

Modified cold drug may work.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- A laboratory study in Germany suggests that a drug now being tested for treating the common cold could be modified to treat SARS, which currently has no known treatment. In a study appearing in the...

Quarantine historically first defense against virus.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- In Milan in 1374, plague victims were ordered to a field outside the city, either to die or recover. Four hundred years later, Egyptian authorities sent the sick to pesthouses and shot heads of families...

Rothberg Institute using internet to mount computer-based effort against SARS.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- The Rothberg Institute for Childhood Diseases, a nonprofit research institute devoted to discovering and developing drugs for orphan childhood diseases, announced the addition of a recently discovered...

Variant gives clues to origin of infection.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- A genetic study of the SARS virus gives insight into the molecular behavior of the novel coronavirus responsible for SARS. Comparison of a virus isolate from Singapore with isolates from other...

Cidofovir effective but toxic for adenovirus-infected patients.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Cidofovir is effective but toxic for stem cell graft recipients with posttransplant adenovirus infections. "Adenovirus is an important cause of morbidity and mortality after allogeneic...

Cord blood grafts linked to heightened cytomegalovirus risk.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Umbilical cord blood-derived stem cell grafts carry a higher risk of cytomegalovirus (CMV) infection than adult grafts. In a recent study from Japan, CMV infection "in 28 adult patients after cord...

Vaccinia virus vaccine stable whether diluted or undiluted.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- The stability of the vaccinia virus vaccine Dryvax was similar whether it was stored diluted or undiluted. According to a study from the United States, "The stability of Dryvax vaccine was examined...

HAV RNA genotype-determining region is not linked to disease severity.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- HAV RNA genotype-determining region is not linked to disease severity. According to recent research published in the journal Hepatology Research, "although hepatitis A is still a considerable...

Clinical labs could use DNA microarray for detecting hepatitis B virus.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Clinical labs could use DNA microarray for detecting hepatitis B virus. "We have developed a sensitive and quantitative assay using a DNA microarray for the detection of hepatitis B virus (HBV) DNA...

Apoptotic signals in hepatitis C virus infection are contradictory.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Apoptotic signals in hepatitis C virus infection are contradictory. "Infection with hepatitis C virus (HCV) is characterized by inflammatory liver damage and a long viral persistence associated with...

Study finds AIDS virus strain crossed into humans by 1940.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- One form of the virus that causes AIDS made the jump from animals to people by 1940, a new analysis indicates. HIV-2 didn't spread across West Africa until the 1960s, perhaps spurred by a war in...

SIV from multiple lineages can infect human macrophages.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Simian immunodeficiency viruses from multiple lineages can infect human macrophages, indicating the potential for cross-species transmission. "Zoonotic transfer of simian immunodeficiency virus...

Researchers find potential drug screening target.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- Researchers at Children's Hospital Boston and Harvard Medical School have located a vulnerable pocket in the protein that coats the dengue virus, a potentially deadly mosquito-transmitted disease that...

Outbreaks could be 'bigger than SARS' in 2003.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- West Nile virus, which sickened 4156 people and resulted in 284 deaths in North America last year, could end up in 2003 having a considerably bigger human and nonhuman impact than that seen to date...

Heparan sulfate not sole mediator of TBE virus cell attachment.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- Heparan sulfate is not the only mediator of TBE virus cell attachment. In a recent study from Austria, "attachment of the flavivirus tick-borne encephalitis (TBE) virus to different permissive cell...

HDV infection persists without hepatitis B virus envelope protein carbohydrates.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- HDV infection persists without hepatitis B virus envelope protein carbohydrates. "Hepatitis delta virus (HDV) particles are coated with the large (L), middle (M), and small (S) hepatitis B virus...

Seronegative subjects retain T cell immunity to herpes simplex virus.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- Silent infection or acquired immunity may be the reason why seronegative subjects retain T cell immunity to the herpes simplex virus. "During the course of investigating T cell responses to HSV...

Two Harvard experts claim West Nile virus could be "bigger than SARS" in 2003.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- According to two Harvard experts, West Nile Virus, which sickened 4,156 people and resulted in 284 deaths in North America last year, could end up in 2003 having a considerably bigger human and...

Vaccine to be developed will be directed against multiple HIV antigens.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- BioVex announced that it has signed a letter of intent with the Vaccine Research Center at the National Institutes of Allergy and Infectious Disease, National Institutes of Health, in relation to the...

New cell lines allow scientists to study lamivudine-resistant hepatitis B.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Stable cell lines that express lamivudine-resistant strains of hepatitis B virus (HBV) have been developed by researchers at Glaxo Wellcome-Heritage Research...

CAR expression makes adenovirus-based therapy viable for osteosarcoma patients.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- CAR expression makes adenovirus-based therapy viable for osteosarcoma patients. According to a study from Japan, "recombinant adenovirus is used as a competent vector in a wide spectrum of cancer...

Therapeutic vaccine effective against EBV-associated cancers.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- A therapeutic LMP1 polyepitope vaccine has been developed for Epstein-Barr virus (EBV)-associated Hodgkin's disease and nasopharyngeal carcinoma. According to a study from Australia, "Development...

Letter to shareholders give corporate update on virus drugs.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- The following is a letter from Geert Kersten, CEO, and Maximilian de Clara, president, of Cel-Sci Corporation (CVM) to its shareholders: In our March 12, 2003, shareholder letter we outlined our...

CalbaTech submits proposal through BioSTAR program.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- CalbaTech, Inc., (CLBE) announced that the company has submitted a collaborative proposal with a prominent University of California researcher through the BioSTAR Program, which fosters research in...

Genetically engineered virus causes total regression of deadly brain cancer.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Scientists at the Mayo Clinic have evaluated a new genetically engineered measles virus with the ability to fight glioblastoma multiforme, a deadly form of...

Viral cytopathicity heightened in advanced disease.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- Viral cytopathicity increases with HIV disease progression. "The presence of only non-syncytium-inducing beta-chemokine receptor 5-restricted (R5/NSI) human immunodeficiency virus type 1 (HIV-1)...

Extended viral kinetic models may improve treatment efficacy.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- Extended models of HIV kinetics may improve the efficacy of antiretroviral therapy. "Clinical markers in the peripheral blood guide the treatment of human immunodeficiency virus type I (HIV-1),"...

HCV replication occurs on a membranous web in liver cancer cells.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- HCV replication occurs on a membranous web in liver cancer cells. According to a study from Germany, "Formation of a membrane-associated replication complex, composed of viral proteins,...

Light chain variability creates B cell diversity that prevents infections.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- Combinatorial immunoglobulin light chain variability creates sufficient B cell diversity to mount protective antibody responses against pathogen infections. According to published research from...

Ligands binding human prion proteins targeted.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- Scientists at Pathogen Removal and Diagnostic Technologies Inc. (PRDT), a joint venture company set up by the American Red Cross and ProMetic Life Sciences Inc., have selected seven ligands that bind...

Blood screening test detects other members of the West Nile virus family.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- Roche Diagnostics announced that U.S. and Canadian clinical trials for its new assay for detecting West Nile virus in donated blood are scheduled to being by July 1. While the trials are designed...

Hepatoma hepatitis B virus variants collect in B- and T-cell epitopes of HBx.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- Hepatoma hepatitis B virus variants collect in B- and T-cell epitopes of HBx. "Hepatitis B virus (HBV) X gene, encoding a pleotropic transactivator of HBx protein, has been associated with the...

Hepatitis C virus nonstructural proteins display complex interactions.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus nonstructural proteins display a variety of complex interactions. According to a study from France, "replication of the hepatitis C virus (HCV) genome has been proposed to take...

Alliance signed for SARS diagnostic test.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- Abbott Laboratories (ABT) announced a worldwide marketing and distribution agreement with German-based Artus GmbH for the first commercial test to detect a form of the coronavirus suspected of causing...

Compounds show "moderate" in vitro activity against SARS virus.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- A number of experimental compounds provided by Pfizer Inc to the U.S. government for testing against a strain of the coronavirus, which is associated with severe acute respiratory syndrome (SARS), have...

Virus researchers close in on the secret life of DNA.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- Z-DNA, a long-known but still mysterious alternate configuration of DNA, is involved in cellular defenses against viral attack according to the results of a series of experiments linking Z-DNA binding...

Hepatitis C drug market to grow to $9 billion in 2012.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- Decision Resources, Inc., one of the world's leading research and advisory firms focusing on pharmaceutical and healthcare issues, finds that the hepatitis C virus (HCV) drug market will grow from $2.5...

Genotype 1a subgenomic hepatitis C virus replicons advance viral analysis.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- "Recently, cell-based replicon systems for hepatitis C virus (HCV), in which the nonstructural proteins stably replicate subgenomic viral RNA in Huh? cells, were developed. To date, one limitation of...

Diverse treatment goals alter the way viral vectors can be used for therapy.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- Diverse therapeutic goals alter the way viral vectors can be used for therapy. "The idea of using viruses as gene vehicles to combat disease is tantalizing for the simplicity of its principle, and...

Protective gene mutation found in some HIV patients.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- Mayo Clinic researchers have identified a naturally occurring "good guy" for patients infected with HIV. It is a helpful gene mutation that impairs the HIV virus' cell-killing machinery, thus...

Reticuloendotheliosis viruses are suited for vector use in human gene therapy.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- Reticuloendotheliosis viruses are suited for vector use in human gene therapy. "The reticuloendotheliosis viruses (REV) spleen necrosis virus (SNV) and reticuloendotheliosis virus strain-A (REV-A)...

Scientists engineering better approach to HIV treatment with designer molecules.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- Ravi Kane, assistant professor of chemical engineering at Rensselaer Polytechnic Institute, is designing brand-new molecules that may one day fend off an HIV infection. Bolstering the body's...

The topology of hepatitis C virus protein NS4B suggests many shared functions.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- The topology of hepatitis C virus protein NS4B suggests many shared functions. According to recent research from Sweden, "hepatitis C virus (HCV) belongs to the Hepacivirus genus in the...

Other viral infections common among HIV-infected women.
June 10, 2003... 2003 JUN 10 - (NewsRx.com & NewsRx.net) -- Other viral infections are common among HIV-infected and high-risk HIV-uninfected women. According to a study from the United States, "Viruses that can persist in the host are of special concern...

Hepatitis C virus prevents HAART-induced immune deactivation.
June 17, 2003... 2003 JUN 17 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus (HCV) prevents immune deactivation in HIV patients treated with antiretroviral agents. The impact of HCV coinfection "on the kinetics of serum beta 2-microglobulin levels in...

Chest imaging studies play key role in SARS diagnosis.
June 17, 2003... 2003 JUN 17 - (NewsRx.com & NewsRx.net) -- At least until definitive tests are available, chest radiographs (x-rays) and computed tomography (CT) scans will play a critical role in the diagnosis of severe acute respiratory syndrome (SARS),...

Scientists uncover HIV escape route from drugs and vaccines.
June 17, 2003... 2003 JUN 17 - (NewsRx.com & NewsRx.net) -- Virologists at Jefferson Medical College may have discovered a new way by which HIV can evade both antiviral drugs and vaccines. Researchers had reported last summer that a protein called CEM15 is...

Nanoparticle-supported gene probes visualize HBV and HCV genotypes.
June 17, 2003... 2003 JUN 17 - (NewsRx.com & NewsRx.net) -- Nanoparticle-supported gene probes visualize HBV and HCV genotypes. "A visual gene-detecting technique using nanoparticle-supported gene probes is described. With the aid of gold...

Glycoprotein trafficking in hantaviruses investigated.
June 17, 2003... 2003 JUN 17 - (NewsRx.com & NewsRx.net) -- Glycoprotein trafficking in hantaviruses has been investigated. According to published research from the United States, "Sin Nombre virus (SNV) is a major representative of the New World...

Substitutions in the gamma(1)34.5 protein can eliminate IFN-alpha resistance.
June 17, 2003... 2003 JUN 17 - (NewsRx.com & NewsRx.net) -- The effector domain of the gamma(1)34.5 protein of herpes simplex virus 1 has a few substitution points that can create sensitivity to interferon-alpha. "The gamma(1)34.5 protein of herpes simplex...

Licensing agreement announced for antiviral compound MIV-210.
June 17, 2003... 2003 JUN 17 - (NewsRx.com & NewsRx.net) -- GlaxoSmithKline (GSK) and Medivir announced that they have signed a licensing agreement for MIV-210, a nucleoside analogue reverse transcriptase inhibitor (NRTI) that has recently begun phase I...

Interferon wipes out hepatitis C virus-associated cryoglobulinemia symptoms.
June 17, 2003... 2003 JUN 17 - (NewsRx.com & NewsRx.net) -- Interferon wipes out hepatitis C virus-associated cryoglobulinemia symptoms. "We describe a 54-year-old man with hepatitis C virus (HCV) infection-associated cryo-globulinemia type III. The patient...

Oncolytics announces issuance of seventh U.S. patent.
June 17, 2003... 2003 JUN 17 - (NewsRx.com & NewsRx.net) -- Oncolytics Biotech, Inc., (ONCY) announced that it has been granted U.S. patent 6,565,831 entitled "Method of Preventing Reovirus Recognition for the Treatment of Cellular Proliferative Disorders." ...